公开(公告)号：US20240299054A1

公开(公告)日：2024-09-12

申请号：US18437279

申请日：2024-02-09

申请人： K1MED GLOBAL INC.

发明人： Sangsik KIM

IPC分类号： A61B17/225 ,  A61B17/00 ,  B06B1/06

CPC分类号： A61B17/2251 ,  B06B1/0637 ,  A61B2017/0046 ,  A61B2017/2253 ,  B06B2201/76

摘要： A multi-focal shockwave output handle unit for an extracorporeal shockwave therapy device using a multi-piezoelectric configuration includes a high-intensity focused ultrasound generator that is provided on a front end part of a handle that is provided to be gripped by a user, and generates high-intensity focused ultrasound (HIFU) on the basis of an applied electric signal; a cover unit that is connected to the front end part of the handle; a radiation-surface base unit that is connected to a front end part of the cover unit; a piezoelectric ceramic unit that includes a plurality of piezoelectric ceramic members arranged on the front inner curved surface of the cover unit or the rear outer curved surface of the radiation-surface base unit; and a gel pad unit that is connected to a front end part of the radiation-surface base unit.

公开(公告)号：US09878506B2

公开(公告)日：2018-01-30

申请号：US14970704

申请日：2015-12-16

申请人： Massachusetts Institute of Technology

发明人： Xuanhe Zhao ,  Shaoting Lin ,  Hyunwoo Yuk

IPC分类号： A61K9/00 ,  B29C71/00 ,  A61K49/22 ,  A61B8/00 ,  C08J3/075 ,  C08J3/24 ,  B29K105/00 ,  A61B17/225

CPC分类号： B29C71/0009 ,  A61B8/4281 ,  A61B2017/2253 ,  A61K49/226 ,  B29K2105/0061 ,  B29K2995/0078 ,  C08J3/075 ,  C08J3/246 ,  C08J2300/14 ,  C08J2300/208 ,  C08J2333/26

摘要： Method for making a tough and compliant hydrogel. A precursor hydrogel is made of a first polymer selected to maintain high elasticity and a second polymer selected to dissipate mechanical energy. The precursor hydrogel is stretched to a multiple of its original length to form a pre-stretched hydrogel. The pre-stretched hydrogel is allowed to relax and is soaked in a biocompatible solvent to reach equilibrium swelling of the pre-stretched hydrogel whereby shear modulus of the hydrogel is reduced.

公开(公告)号：US20170151708A1

公开(公告)日：2017-06-01

申请号：US15415543

申请日：2017-02-16

申请人： Ethicon LLC

发明人： Timothy G. Dietz ,  Foster B. Stulen ,  William A. Olson ,  William D. Dannaher ,  John W. Willis ,  Sora Rhee ,  Juergen Burger ,  Phillippe Margairaz ,  Robert Lockhart ,  Franz Friedrich ,  Danik Brand ,  Herbert Keppner ,  Jean-Paul Sandoz

IPC分类号： B29C65/48 ,  A61M37/00 ,  B29C65/00 ,  A61N7/02

CPC分类号： A61N7/00 ,  A61B8/4272 ,  A61B2017/00473 ,  A61B2017/00964 ,  A61B2017/2253 ,  A61B2017/306 ,  A61B2017/32007 ,  A61B2017/320073 ,  A61B2017/320084 ,  A61B2017/320088 ,  A61B2017/320089 ,  A61B2017/320098 ,  A61B2217/005 ,  A61B2217/007 ,  A61M37/0092 ,  A61M2207/00 ,  A61N7/02 ,  A61N2007/0034 ,  A61N2007/0078 ,  A61N2007/0082 ,  B06B3/00 ,  B29C65/48 ,  B29C66/01 ,  B29L2031/753 ,  G10K11/24 ,  Y10T156/10 ,  Y10T156/1062

摘要： Ultrasound surgical apparatus are disclosed, including: medical ultrasound handpieces with proximally mounted ultrasound radiators configured to create a distally-focused beam of ultrasound energy, in combination with distal guide members for control of focal point depth; medical ultrasound handpieces with proximally mounted ultrasound radiators configured to create a distally-focused beam of ultrasound energy, in combination with distal rolling members for manipulability and control of focal point depth; medical ultrasound handpiece assemblies with coupled end effectors providing a probe with a probe dilation region configured to have an average outside diameter that is equal to or greater than the average outside diameter of a probe tip and neck; as well as junctions to an ultrasonically inactive probe sheath; medical ultrasound handpiece assemblies with coupled end effectors having positionable, ultrasonically inactive probe sheath ends slidably operable to both cover and expose at least a probe tip; and ultrasound transducer cores including a transducer structure affixed to a longitudinally elongated, generally planar, single crystal or polycrystalline material waveguide.

公开(公告)号：US09526923B2

公开(公告)日：2016-12-27

申请号：US14746692

申请日：2015-06-22

申请人： HISTOSONICS, INC ,  THE REGENTS OF THE UNIVERSITY OF MICHIGAN

发明人： Russell C. Jahnke ,  James A. Bertolina ,  William W. Roberts ,  Charles A. Cain ,  Dejan Teofilovic ,  Thomas W. Davison

IPC分类号： A61B8/00 ,  A61N7/00 ,  A61B8/12 ,  A61B17/225 ,  A61B17/00 ,  A61B18/00

CPC分类号： A61N7/00 ,  A61B8/12 ,  A61B8/4272 ,  A61B8/4281 ,  A61B8/445 ,  A61B17/2251 ,  A61B17/2256 ,  A61B2017/00274 ,  A61B2017/2253 ,  A61B2018/00547 ,  A61B2090/378 ,  A61N2007/0039 ,  A61N2007/0043

摘要： A medical imaging and therapy device is provided that may include any of a number of features. One feature of the device is that it can acoustically couple an ultrasound therapy transducer to a patient. In some embodiments, the medical imaging and therapy device is configured to conform to the anatomy of a patient's perineal area to acoustically couple an ultrasound therapy transducer to the patient for treatment of BPH. The medical imaging and therapy device can be used in therapeutic applications such as Histotripsy, Lithotripsy, and HIFU, for example. Methods associated with use of the medical imaging and therapy device are also covered.

公开(公告)号：US09492687B2

公开(公告)日：2016-11-15

申请号：US13519954

申请日：2011-01-03

申请人： George K. Lewis, Jr.

发明人： George K. Lewis, Jr.

IPC分类号： A61N7/00 ,  A61B8/00 ,  A61B17/225

CPC分类号： A61N7/00 ,  A61B8/4227 ,  A61B8/4236 ,  A61B8/4281 ,  A61B8/44 ,  A61B8/4427 ,  A61B17/2251 ,  A61B2017/00734 ,  A61B2017/2253 ,  A61N2007/006 ,  A61N2007/0078 ,  A61N2007/0091 ,  A61N2007/0095 ,  Y10T29/49005

摘要： The present invention relates to a low-profile ultrasound transducer. The low-profile ultrasound transducer includes a piezoelectric component operative to receive a driving signal from an energy generating module and to emit the driving signal as ultrasonic energy. The piezoelectric component has a front surface and a back surface, and the energy generating module includes a plurality of electronic components. The low-profile ultrasound transducer also includes a lens component directly or indirectly deposited on the front surface of the piezoelectric component. The lens component includes a lens portion and a support portion. The lens portion of the lens component is configured to control the direction and wave pattern of the ultrasonic energy emitted from the piezoelectric component. The support portion of the lens component is configured to hold the piezoelectric component in place and to provide a chamber for housing at least one electronic component of the energy generating module. Methods of use and related devices are also disclosed.

摘要翻译： 本发明涉及一种低调超声波换能器。 低调超声波换能器包括压电元件，其操作以接收来自能量产生模块的驱动信号，并且以超声能量发射驱动信号。 压电元件具有前表面和后表面，能量产生模块包括多个电子部件。 低剖面超声波换能器还包括直接或间接沉积在压电元件的前表面上的透镜部件。 透镜部件包括透镜部分和支撑部分。 透镜部件的透镜部分被配置为控制从压电元件发射的超声波能量的方向和波形图案。 透镜部件的支撑部分构造成将压电部件保持就位并提供用于容纳能量产生模块的至少一个电子部件的室。 还公开了使用方法和相关装置。

公开(公告)号：US20160022294A1

公开(公告)日：2016-01-28

申请号：US14874650

申请日：2015-10-05

申请人： SANUWAVE, INC.

发明人： Iulian CIOANTA ,  Christopher M. CASHMAN

IPC分类号： A61B17/22

CPC分类号： A61B17/22012 ,  A61B17/22 ,  A61B17/22004 ,  A61B17/2202 ,  A61B17/22022 ,  A61B17/22029 ,  A61B17/225 ,  A61B17/2255 ,  A61B18/245 ,  A61B18/26 ,  A61B2017/00867 ,  A61B2017/22014 ,  A61B2017/22024 ,  A61B2017/22025 ,  A61B2017/22039 ,  A61B2017/22051 ,  A61B2017/22054 ,  A61B2017/22067 ,  A61B2017/22079 ,  A61B2017/22082 ,  A61B2017/22084 ,  A61B2017/2212 ,  A61B2017/2253 ,  A61H9/0057 ,  A61H23/008 ,  A61H2201/14 ,  A61H2201/1664 ,  A61N2007/0008 ,  G10K11/28

摘要： An intracorporeal pressure shock wave device to provide treatment within blood vessels artificial vessels and grafts that includes a frontal pressure shock wave reflector positioned at the distal end of an intracorporeal catheter to direct shock waves toward a treatment target, such as an occlusion and clot.

摘要翻译： 一种体内压力冲击波装置，用于在血管内提供人造血管和移植物，其包括位于体内导管远端的正面压力冲击波反射器，以将冲击波引向治疗目标，例如闭塞和凝块。

公开(公告)号：US09061131B2

公开(公告)日：2015-06-23

申请号：US12858242

申请日：2010-08-17

申请人： Russell C. Jahnke ,  James A. Bertolina ,  William W. Roberts ,  Charles A. Cain ,  Dejan Teofilovic ,  Thomas W. Davison

发明人： Russell C. Jahnke ,  James A. Bertolina ,  William W. Roberts ,  Charles A. Cain ,  Dejan Teofilovic ,  Thomas W. Davison

IPC分类号： A61B8/00 ,  A61N7/00 ,  A61B8/12 ,  A61B17/225 ,  A61B17/00 ,  A61B18/00 ,  A61B19/00

CPC分类号： A61N7/00 ,  A61B8/12 ,  A61B8/4272 ,  A61B8/4281 ,  A61B8/445 ,  A61B17/2251 ,  A61B17/2256 ,  A61B2017/00274 ,  A61B2017/2253 ,  A61B2018/00547 ,  A61B2090/378 ,  A61N2007/0039 ,  A61N2007/0043

摘要： A medical imaging and therapy device is provided that may include any of a number of features. One feature of the device is that it can acoustically couple an ultrasound therapy transducer to a patient. In some embodiments, the medical imaging and therapy device is configured to conform to the anatomy of a patient's perineal area to acoustically couple an ultrasound therapy transducer to the patient for treatment of BPH. The medical imaging and therapy device can be used in therapeutic applications such as Histotripsy, Lithotripsy, and HIFU, for example. Methods associated with use of the medical imaging and therapy device are also covered.

摘要翻译： 提供了可以包括许多特征中的任何一个的医学成像和治疗装置。 该装置的一个特点是它可以将超声治疗换能器声学耦合到患者。 在一些实施例中，医学成像和治疗装置被配置为符合患者的会阴区域的解剖结构，以便将超声治疗换能器声学耦合到患者以治疗BPH。 医学成像和治疗装置可用于治疗应用，例如组织切除术，碎石术和HIFU。 还涉及与使用医学成像和治疗装置相关的方法。

公开(公告)号：US09028471B2

公开(公告)日：2015-05-12

申请号：US13509895

申请日：2010-11-23

申请人： Thierry Pechoux

发明人： Thierry Pechoux

IPC分类号： A61B18/04 ,  A61B19/02 ,  A61B8/00 ,  A61N7/02 ,  A61B17/00 ,  A61B17/225 ,  A61B18/00

CPC分类号： A61B19/02 ,  A61B8/4422 ,  A61B50/00 ,  A61B2017/00084 ,  A61B2017/2253 ,  A61B2018/00023 ,  A61N7/02

摘要： This invention concerns a cover member, especially for a HIFU head, comprising a peripheral outer wall, an open first side configured to partially cover an ultrasound head and a closed second side comprising a flexible membrane adapted for contact with a patient's skin, characterized in that the cover member is removeably attachable to the tip of said ultrasound probe.

摘要翻译： 本发明涉及一种盖构件，特别是用于HIFU头，其包括外围外壁，开放的第一侧，构造成部分地覆盖超声波头，封闭的第二侧包括适于与患者皮肤接触的柔性膜，其特征在于： 盖构件可移除地附接到所述超声波探头的尖端。

公开(公告)号：US20150073311A1

公开(公告)日：2015-03-12

申请号：US14020857

申请日：2013-09-08

申请人： Moshe Ein-Gal

发明人： Moshe Ein-Gal

IPC分类号： A61H23/00

CPC分类号： A61H23/008 ,  A61B17/2251 ,  A61B2017/2253 ,  A61F7/007 ,  A61F2007/0059 ,  A61H2201/0111 ,  A61H2201/105 ,  A61N7/02 ,  A61N2007/0017 ,  A61N2007/0034

摘要： Apparatus includes a treatment bag configured to at least partially encapsulate a body portion to be treated, the treatment bag being generally leak-proof and transparent to acoustic waves and at least partially filled with a shockwave transmission liquid. An acoustic wave device includes a transducer operative to generate acoustic waves. A focusing device focuses the acoustic waves toward a focus. The acoustic wave device is placed near or against the treatment bag and arranged with respect to a target in the body portion, which it is desired to treat, so that the acoustic waves generated by the transducer propagate towards the focus via the shockwave transmission liquid in the bag.

摘要翻译： 设备包括处理袋，其被配置为至少部分地包封待处理的主体部分，所述处理袋通常对声波是防泄漏和透明的，并且至少部分地填充有冲击波传输液体。 声波装置包括可产生声波的换能器。 聚焦装置将声波聚焦成焦点。 声波装置放置在治疗袋附近或靠近处理袋并且相对于所需体内部分中的目标被布置，这是希望处理的，使得由换能器产生的声波通过冲击波传输液体朝向焦点传播 袋子。

公开(公告)号：US20140323864A1

公开(公告)日：2014-10-30

申请号：US14327881

申请日：2014-07-10

申请人： Guided Therapy Systems, LLC

发明人： Peter G. Barthe ,  Michael H. Slayton ,  T Douglas Mast ,  Inder Raj S. Makin ,  Jeffrey D. Messerly ,  Waseem Faidi ,  Megan M. Runk

IPC分类号： A61B8/00 ,  A61N7/00 ,  A61B8/12

CPC分类号： A61B8/4272 ,  A61B8/12 ,  A61B8/4281 ,  A61B8/4444 ,  A61B8/546 ,  A61B2017/2253 ,  A61N7/00 ,  A61N7/022 ,  A61N2007/0052

摘要： An ultrasound medical system has an end effector including a medical ultrasound transducer and an acoustic coupling medium. The acoustic coupling medium has a transducer-proximal surface and a transducer-distal surface. The medical ultrasound transducer is positioned to emit medical ultrasound through the acoustic coupling medium from the transducer-proximal surface to the transducer-distal surface. The end effector is adapted to change a property (such as the shape and/or the temperature) of the acoustic coupling medium during emission, and/or between emissions, of medical ultrasound from the medical ultrasound transducer during a medical procedure on a patient. In one example, such changes are used to change the focus and/or beam angle of the emitted ultrasound during the medical procedure.

摘要翻译： 超声波医疗系统具有包括医用超声波换能器和声耦合介质的末端执行器。 声耦合介质具有换能器近侧表面和换能器远侧表面。 医疗超声换能器被定位成通过声耦合介质从换能器近端表面到换能器远侧表面发射医用超声波。 端部执行器适于在医疗超声波换能器在患者的医疗过程期间改变声学耦合介质在发射期间和/或发射之间的医疗超声波的性质（例如形状和/或温度）。 在一个示例中，这样的改变用于在医疗过程期间改变发射的超声的焦点和/或束角。