公开(公告)号：US20180126677A1

公开(公告)日：2018-05-10

申请号：US15846301

申请日：2017-12-19

申请人： Massachusetts Institute of Technology

发明人： Xuanhe Zhao ,  Shaoting Lin ,  Hyunwoo Yuk

IPC分类号： B29C71/00 ,  C08J3/075 ,  A61K49/22 ,  A61B8/00 ,  C08J3/24 ,  A61B17/225 ,  B29K105/00

CPC分类号： B29C71/0009 ,  A61B8/4281 ,  A61B2017/2253 ,  A61K49/226 ,  B29K2105/0061 ,  B29K2995/0078 ,  C08J3/075 ,  C08J3/246 ,  C08J2300/14 ,  C08J2300/208 ,  C08J2333/26

摘要： A method for making a tough and compliant hydrogel. A precursor hydrogel is made of a first polymer selected to maintain high elasticity and a second polymer selected to dissipate mechanical energy. The precursor hydrogel is stretched to a multiple of its original length to form a pre-stretched hydrogel. The pre-stretched hydrogel is allowed to relax and is soaked in a biocompatible solvent to reach equilibrium swelling of the pre-stretched hydrogel whereby shear modulus of the hydrogel is reduced.

公开(公告)号：US20180001113A1

公开(公告)日：2018-01-04

申请号：US15198641

申请日：2016-06-30

申请人： L'OREAL

发明人： John STREETER

IPC分类号： A61N7/00 ,  A61M35/00 ,  A61M37/00

CPC分类号： A61N7/00 ,  A61B17/2251 ,  A61B2017/2253 ,  A61M35/00 ,  A61M37/0092 ,  A61M2205/058 ,  A61N7/02 ,  A61N2007/0034

摘要： A dermal device for providing ultrasound therapy to skin is provided including: a transducer assembly including housing structure having an inner surface defining a void and configured to contact an outer portion of an area of skin of a user without contacting an inner portion of the area of skin; and an ultrasound transducer supported by the housing and configured to be disposed proximate the void, wherein the ultrasound transducer is configured to provide ultrasound energy with a focal point towards the skin.

公开(公告)号：US20160176128A1

公开(公告)日：2016-06-23

申请号：US14970704

申请日：2015-12-16

申请人： Massachusetts Institute of Technology

发明人： Xuanhe Zhao ,  Shaoting Lin ,  Hyunwoo Yuk

IPC分类号： B29C71/00 ,  A61K49/22

CPC分类号： B29C71/0009 ,  A61B8/4281 ,  A61B2017/2253 ,  A61K49/226 ,  B29K2105/0061 ,  B29K2995/0078 ,  C08J3/075 ,  C08J3/246 ,  C08J2300/14 ,  C08J2300/208 ,  C08J2333/26

摘要： Method for making a tough and compliant hydrogel. A precursor hydrogel is made of a first polymer selected to maintain high elasticity and a second polymer selected to dissipate mechanical energy. The precursor hydrogel is stretched to a multiple of its original length to form a pre-stretched hydrogel. The pre-stretched hydrogel is allowed to relax and is soaked in a biocompatible solvent to reach equilibrium swelling of the pre-stretched hydrogel whereby shear modulus of the hydrogel is reduced.

摘要翻译： 制造坚韧和顺应性水凝胶的方法。 前体水凝胶由选择为保持高弹性的第一聚合物和选择用于耗散机械能的第二聚合物制成。 将前体水凝胶拉伸至其原始长度的倍数以形成预拉伸的水凝胶。 使预拉伸的水凝胶松弛并浸泡在生物相容性溶剂中以达到预拉伸水凝胶的平衡溶胀，从而降低水凝胶的剪切模量。

公开(公告)号：US09199096B2

公开(公告)日：2015-12-01

申请号：US13519951

申请日：2011-01-03

申请人： George K. Lewis, Jr.

发明人： George K. Lewis, Jr.

IPC分类号： A61B5/05 ,  A61N7/00 ,  A61B8/00 ,  A61B17/225

CPC分类号： A61N7/00 ,  A61B8/4227 ,  A61B8/4236 ,  A61B8/4281 ,  A61B8/44 ,  A61B8/4427 ,  A61B17/2251 ,  A61B2017/00734 ,  A61B2017/2253 ,  A61N2007/006 ,  A61N2007/0078 ,  A61N2007/0091 ,  A61N2007/0095 ,  Y10T29/49005

摘要： The present invention relates to a portable ultrasound system that can be used for a wide range of ultrasound applications. The portable ultrasound system includes an energy generating module operative to generate a driving signal that can be transformed into ultrasonic energy, where the energy generating module includes a power source, an oscillator, and a driver component. The portable ultrasound system also includes an ultrasound transducer having a piezoelectric component and a lens component. The ultrasound transducer is operative to receive the driving signal from the energy generating module, to transform the driving signal into ultrasonic energy, and to control the direction of the ultrasonic energy emitted from the ultrasound transducer. Also disclosed are devices containing the portable therapeutic ultrasound system of the present invention, as well as methods of using the system.

摘要翻译： 便携式超声波系统技术领域本发明涉及可用于大范围超声应用的便携式超声系统。 便携式超声系统包括能量产生模块，其可操作以产生可转换成超声能量的驱动信号，其中能量产生模块包括电源，振荡器和驱动器部件。 便携式超声系统还包括具有压电元件和透镜部件的超声换能器。 所述超声波换能器用于接收来自所述能量产生模块的驱动信号，以将所述驱动信号转换成超声波能量，并控制从所述超声换能器发射的超声能量的方向。 还公开了包含本发明的便携式治疗超声系统的装置以及使用该系统的方法。

公开(公告)号：US20150290477A1

公开(公告)日：2015-10-15

申请号：US14746692

申请日：2015-06-22

申请人： Russell C. JAHNKE ,  James A. BERTOLINA ,  William W. ROBERTS ,  Charles A. CAIN ,  Dejan TEOFILOVIC ,  Thomas W. DAVISON

发明人： Russell C. JAHNKE ,  James A. BERTOLINA ,  William W. ROBERTS ,  Charles A. CAIN ,  Dejan TEOFILOVIC ,  Thomas W. DAVISON

IPC分类号： A61N7/00

CPC分类号： A61N7/00 ,  A61B8/12 ,  A61B8/4272 ,  A61B8/4281 ,  A61B8/445 ,  A61B17/2251 ,  A61B17/2256 ,  A61B2017/00274 ,  A61B2017/2253 ,  A61B2018/00547 ,  A61B2090/378 ,  A61N2007/0039 ,  A61N2007/0043

摘要： A medical imaging and therapy device is provided that may include any of a number of features. One feature of the device is that it can acoustically couple an ultrasound therapy transducer to a patient. In some embodiments, the medical imaging and therapy device is configured to conform to the anatomy of a patient's perineal area to acoustically couple an ultrasound therapy transducer to the patient for treatment of BPH. The medical imaging and therapy device can be used in therapeutic applications such as Histotripsy, Lithotripsy, and HIFU, for example. Methods associated with use of the medical imaging and therapy device are also covered.

摘要翻译： 提供了可以包括许多特征中的任何一个的医学成像和治疗装置。 该装置的一个特点是它可以将超声治疗换能器声学耦合到患者。 在一些实施例中，医学成像和治疗装置被配置为符合患者的会阴区域的解剖结构，以便将超声治疗换能器声学耦合到患者以治疗BPH。 医学成像和治疗装置可用于治疗应用，例如组织切除术，碎石术和HIFU。 还涉及与使用医学成像和治疗装置相关的方法。

公开(公告)号：US09144421B1

公开(公告)日：2015-09-29

申请号：US12641248

申请日：2009-12-17

申请人： Michael P. H. Lau ,  David P. Nelson

发明人： Michael P. H. Lau ,  David P. Nelson

IPC分类号： A61B8/00 ,  A61B17/00 ,  A61B17/42

CPC分类号： A61B17/00 ,  A61B17/42 ,  A61B2017/00084 ,  A61B2017/00557 ,  A61B2017/00902 ,  A61B2017/00915 ,  A61B2017/2253 ,  A61B2017/4216 ,  A61B2017/4225 ,  A61B2018/00559 ,  A61B2090/0472 ,  A61B2090/064 ,  A61N7/02 ,  A61N2007/0069

摘要： A method and apparatus for treating uterine tissue with ultrasound energy. The method manipulates the position of the patient's uterus to decrease its distance from an ultrasound therapy transducer while simultaneously engaging a partially filled bladder such that the bladder is compressed to force any bowel tissue out of an acoustic window between the patient's abdominal wall and uterus. Ultrasound energy is then applied to the uterine tissue.

摘要翻译： 一种用超声能量治疗子宫组织的方法和装置。 该方法操纵患者子宫的位置以减小其与超声治疗换能器的距离，同时同时接合部分填充的膀胱，使得膀胱被压缩以迫使任何肠组织离开患者的腹壁和子宫之间的声窗口。 然后将超声能量施加到子宫组织。

公开(公告)号：US08834416B2

公开(公告)日：2014-09-16

申请号：US13793518

申请日：2013-03-11

申请人： Boston Scientific Scimed Inc.

发明人： Ronald A. Sahatjian ,  Arthur Madenjian ,  William R. Little

IPC分类号： A61F7/12 ,  A61L26/00 ,  A61M5/32 ,  A61B17/22 ,  A61M5/178 ,  A61B17/221 ,  A61M5/20 ,  A61L27/52 ,  A61L31/14 ,  A61M25/00 ,  A61B17/00 ,  A61B17/225 ,  A61B17/34 ,  A61B19/00

CPC分类号： A61B17/221 ,  A61B17/00491 ,  A61B17/22 ,  A61B17/22004 ,  A61B17/22012 ,  A61B17/3478 ,  A61B2017/2253 ,  A61B2090/0815 ,  A61L26/008 ,  A61L27/52 ,  A61L31/145 ,  A61M5/178 ,  A61M5/20 ,  A61M5/32 ,  A61M25/00

摘要： Stabilizing an object in the body of a patient involves the injection of a lower critical solution temperature (LCST) material or other flowable material into the body of the patient so that the material contacts the object. The LCST material or other flowable material then forms a gel in the body such that the object is contained at least partially within the gel and thereby stabilized by the gel such that the object can then be easily fragmented within the body and/or retrieved from the body.

公开(公告)号：US20140257108A1

公开(公告)日：2014-09-11

申请号：US14181130

申请日：2014-02-14

申请人： G. Chad MORGAN

发明人： G. Chad MORGAN

IPC分类号： A61B8/00

CPC分类号： A61B8/4281 ,  A61B8/4455 ,  A61B2017/2253 ,  A61N7/00 ,  A61N2007/0078

摘要： Embodiments associated with ultrasound conductive medium are described. In one embodiment, an ultrasound conductive medium is formed into a preconfigured shape that is a structure configured to attach over a head of an ultrasound device.

摘要翻译： 描述了与超声波导电介质相关的实施例。 在一个实施例中，超声波导电介质形成为预配置形状，其是被配置为附接在超声装置的头部上的结构。

公开(公告)号：US20130131704A1

公开(公告)日：2013-05-23

申请号：US13509895

申请日：2010-11-23

申请人： Thierry Pechoux

发明人： Thierry Pechoux

IPC分类号： A61B19/02 ,  A61N7/02

CPC分类号： A61B19/02 ,  A61B8/4422 ,  A61B50/00 ,  A61B2017/00084 ,  A61B2017/2253 ,  A61B2018/00023 ,  A61N7/02

摘要： This invention concerns a cover member, especially for a HIFU head, comprising a peripheral outer wall, an open first side configured to partially cover an ultrasound head and a closed second side comprising a flexible membrane adapted for contact with a patient's skin, characterized in that the cover member is removeably attachable to the tip of said ultrasound probe.

摘要翻译： 本发明涉及一种盖构件，特别是用于HIFU头，其包括外围外壁，开放的第一侧，构造成部分地覆盖超声波头，封闭的第二侧包括适于与患者皮肤接触的柔性膜，其特征在于： 盖构件可移除地附接到所述超声波探头的尖端。

公开(公告)号：US08414472B2

公开(公告)日：2013-04-09

申请号：US12338770

申请日：2008-12-18

申请人： Ulrich Hagelauer

发明人： Ulrich Hagelauer

IPC分类号： A61B1/00 ,  A61B1/04 ,  A61B6/00 ,  A61M37/00 ,  A61N2/00

CPC分类号： A61B17/2256 ,  A61B17/2258 ,  A61B90/36 ,  A61B2017/2253 ,  A61B2034/2051 ,  A61B2090/061 ,  A61B2090/376 ,  A61B2090/3954 ,  A61B2090/3958

摘要： The invention generally relates to apparatuses and methods for shock wave treatment of the human body. In particular, the invention relates to navigational aspects of the shock wave treatments, including apparatuses and methods which enable accurate focusing of shock waves.

摘要翻译： 本发明一般涉及人体冲击波治疗的装置和方法。 特别地，本发明涉及冲击波处理的导航方面，包括能够精确地聚焦冲击波的装置和方法。