公开(公告)号：US20200172853A1

公开(公告)日：2020-06-04

申请号：US16774991

申请日：2020-01-28

Applicant: Calysta, Inc.

Inventor： Luan Thanh NGUYEN ,  Arild Johannessen ,  Graham Ian Aylen ,  Joshua A. Silverman

IPC: C12M1/00 ,  C12M1/42 ,  C12M1/34 ,  C12N1/30

Abstract: Reactors, systems and processes for the production of biomass by culturing microorganisms in aqueous liquid culture medium circulating inner loop reactor which utilize nonvertical pressure reduction zones are described. Recovery and processing of the culture microorganisms to obtain products, such as proteins or hydrocarbons is described.

公开(公告)号：US10538730B2

公开(公告)日：2020-01-21

申请号：US16405587

申请日：2019-05-07

Applicant: Calysta, Inc.

Inventor： Luan Thanh Nguyen ,  Arild Johannessen ,  Graham Ian Aylen ,  Joshua A. Silverman

IPC: C12N1/30 ,  C12M1/34 ,  C12M1/42 ,  C12M1/00

Abstract: Reactors, systems and processes for the production of biomass by culturing microorganisms in aqueous liquid culture medium circulating inner loop reactor which utilize nonvertical pressure reduction zones are described. Recovery and processing of the culture microorganisms to obtain products, such as proteins or hydrocarbons is described.

公开(公告)号：US20190048308A1

公开(公告)日：2019-02-14

申请号：US16102448

申请日：2018-08-13

Applicant: Calysta, Inc.

Inventor： Luan Thanh NGUYEN ,  Joshua A. Silverman ,  Graham Ian Aylen

IPC: C12M1/00 ,  C12M1/107 ,  C12M1/12

Abstract: Reactors, systems and processes for the production of biomass by culturing microorganisms in aqueous liquid culture medium circulating inner loop reactor which utilize nonvertical pressure reduction zones are described. Recovery and processing of the culture microorganisms to obtain products, such as proteins or hydrocarbons is described.

公开(公告)号：US10190123B2

公开(公告)日：2019-01-29

申请号：US15821510

申请日：2017-11-22

Applicant: CALYSTA, INC.

Inventor： Joshua A. Silverman ,  Effendi Leonard ,  Renee M. Saville

IPC: C12N15/52 ,  C12N1/20 ,  C12N9/00 ,  C12N9/12 ,  C12N9/04

Abstract: The present disclosure relates to genetically engineered methanotrophic bacteria with the capability of growing on a multi-carbon substrate (e.g., glucose) as a primary or sole carbon source and methods for growing methanotrophic bacteria on the multi-carbon substrate.

公开(公告)号：US10113188B2

公开(公告)日：2018-10-30

申请号：US15877747

申请日：2018-01-23

Applicant: Calysta, Inc.

Inventor： Joshua A. Silverman

IPC: C12P7/64 ,  C12N9/00 ,  C12P7/24 ,  C12N9/16 ,  C12P7/42 ,  C12P7/44 ,  C12N15/52 ,  C12N9/02 ,  C12N9/06 ,  C12N9/04

Abstract: The present disclosure provides compositions and methods for biologically producing fatty acid derivatives, such as fatty alcohols, from recombinant C1 metabolizing microorganisms that utilize C1 substrates such as methane or natural gas as a feedstock.

公开(公告)号：US20180251800A1

公开(公告)日：2018-09-06

申请号：US15882393

申请日：2018-01-29

Applicant: Calysta, Inc.

Inventor： Joshua A. Silverman ,  Sol M. Resnick ,  Michael Mendez ,  Renee M. Saville ,  Sungwon Lee ,  Luan Nguyen

IPC: C12P7/64 ,  C10G3/00 ,  C12N15/74 ,  C12N15/52 ,  C10G47/00 ,  C12R1/01 ,  C12N9/00 ,  C12N9/16 ,  C10L1/04 ,  C10L1/02 ,  C12N1/20 ,  C12N9/10 ,  C12N1/16 ,  C12P5/00

CPC classification number: C12P7/6409 ,  C10G3/00 ,  C10G3/50 ,  C10G47/00 ,  C10G2300/1014 ,  C10L1/02 ,  C10L1/04 ,  C10L2200/0469 ,  C10L2270/02 ,  C10L2270/04 ,  C10L2290/26 ,  C12N1/16 ,  C12N1/20 ,  C12N9/1029 ,  C12N9/16 ,  C12N9/93 ,  C12N15/52 ,  C12N15/74 ,  C12P5/00 ,  C12P7/6463 ,  C12P7/649 ,  C12R1/01 ,  C12Y203/01039 ,  C12Y301/02 ,  C12Y602/01003 ,  C12Y604/01002 ,  Y02E50/13 ,  Y02E50/343 ,  Y02P20/52 ,  Y02P30/20

Abstract: The present disclosure relates to bioengineering approaches for producing biofuel and, in particular, to the use of a C1 metabolizing microorganism reactor system for converting C1 substrates, such as methane or methanol, into biomass and subsequently into biofuels, bioplastics, or the like.

公开(公告)号：US09816111B2

公开(公告)日：2017-11-14

申请号：US14429327

申请日：2013-09-18

Applicant: Calysta, Inc.

Inventor： Joshua A. Silverman ,  Thomas Joseph Purcell

IPC: C12P5/02 ,  C12N1/20

CPC classification number: C12P5/026 ,  C12N1/20 ,  C12N9/16 ,  C12N9/88 ,  Y02E50/343

Abstract: The present disclosure relates to biosynthetic methods for producing propylene and to genetically engineered organisms having propylene biosynthesis capability.

公开(公告)号：US20170298315A1

公开(公告)日：2017-10-19

申请号：US15639120

申请日：2017-06-30

Applicant: Calysta, Inc.

Inventor： Joshua A. Silverman ,  Sol M. Resnick ,  Drew D. Regitsky

IPC: C12M1/00 ,  C12M1/12 ,  C12P17/02 ,  C12P7/42 ,  C12P7/18 ,  C12P7/16 ,  C12M1/02 ,  C12M1/08 ,  C12P5/02 ,  C12P7/40

CPC classification number: C12M29/08 ,  C12M23/06 ,  C12M23/34 ,  C12M27/24 ,  C12M29/06 ,  C12M41/24 ,  C12P5/02 ,  C12P7/16 ,  C12P7/18 ,  C12P7/40 ,  C12P7/42 ,  C12P17/02 ,  Y02E50/343 ,  Y02P20/582

Abstract: A fermenter can have at least one hollow fluid conduit disposed at least partially within a vessel. An external circumference of the hollow fluid conduit and an interior circumference of the vessel can define a downward flow path through which a multi-phase mixture including a liquid media and compressed gas substrate bubbles flows. An interior circumference of the hollow fluid conduit can defined an upward flow path which is in fluid communication with the downward flow path. The multi-phase liquid can flow through the upward flow path and exit the fermenter. Cooling may be provided in the hollow fluid conduit or the vessel. One or more backpressor generators can be used to maintain a backpressure on the fermenter. One or more fluid movers can be used to variously create an induced and/or forced flow in the downward and upward flow paths.

公开(公告)号：US20160040198A1

公开(公告)日：2016-02-11

申请号：US14886983

申请日：2015-10-19

Applicant: Calysta, Inc.

Inventor： Joshua A. Silverman ,  Sol M. Resnick ,  Michael Mendez

IPC: C12P7/64 ,  C10G47/00 ,  C10L1/04 ,  C10G3/00

CPC classification number: C12P7/6409 ,  C10G3/00 ,  C10G3/50 ,  C10G47/00 ,  C10G2300/1014 ,  C10L1/02 ,  C10L1/04 ,  C10L2200/0469 ,  C10L2270/02 ,  C10L2270/04 ,  C10L2290/26 ,  C12N1/16 ,  C12N1/20 ,  C12N9/1029 ,  C12N9/16 ,  C12N9/93 ,  C12N15/52 ,  C12N15/74 ,  C12P5/00 ,  C12P7/6463 ,  C12P7/649 ,  C12R1/01 ,  C12Y203/01039 ,  C12Y301/02 ,  C12Y602/01003 ,  C12Y604/01002 ,  Y02E50/13 ,  Y02E50/343 ,  Y02P20/52 ,  Y02P30/20

Abstract: The present disclosure relates to bioengineering approaches for producing biofuel and, in particular, to the use of a C1 metabolizing microorganism reactor system for converting C1 substrates, such as methane or methanol, into biomass and subsequently into biofuels, bioplastics, or the like.

公开(公告)号：US20150353971A1

公开(公告)日：2015-12-10

申请号：US14813804

申请日：2015-07-30

Applicant: Calysta, Inc.

Inventor： Joshua A. Silverman ,  Sol M. Resnick ,  Michael Mendez ,  Renee M. Saville ,  Sungwon Lee ,  Luan Nguyen

IPC: C12P7/64 ,  C12N9/10 ,  C12N9/00 ,  C12N9/16

CPC classification number: C12P7/6409 ,  C10G3/00 ,  C10G3/50 ,  C10G47/00 ,  C10G2300/1014 ,  C10L1/02 ,  C10L1/04 ,  C10L2200/0469 ,  C10L2270/02 ,  C10L2270/04 ,  C10L2290/26 ,  C12N1/16 ,  C12N1/20 ,  C12N9/1029 ,  C12N9/16 ,  C12N9/93 ,  C12N15/52 ,  C12N15/74 ,  C12P5/00 ,  C12P7/6463 ,  C12P7/649 ,  C12R1/01 ,  C12Y203/01039 ,  C12Y301/02 ,  C12Y602/01003 ,  C12Y604/01002 ,  Y02E50/13 ,  Y02E50/343 ,  Y02P20/52 ,  Y02P30/20

Abstract: The present disclosure relates to bioengineering approaches for producing biofuel and, in particular, to the use of a C1 metabolizing microorganism reactor system for converting C1 substrates, such as methane or methanol, into biomass and subsequently into biofuels, bioplastics, or the like.

Abstract translation: 本公开涉及用于生产生物燃料的生物工程方法，特别是使用C1代谢微生物反应器系统来将C1底物如甲烷或甲醇转化为生物质，随后转化为生物燃料，生物塑料等。