知搜-全球专利检索

  1. Login
  2. Sign Up

Search Results

49 records (took 0.022 seconds)

    Wide dynamic range chemical array reader
    31.
    发明授权
    Wide dynamic range chemical array reader 失效
    宽动态范围化学阵列阅读器

    公开(公告)号：US07463357B2

    公开(公告)日：2008-12-09

    申请号：US11290100

    申请日：2005-11-29

    Applicant: John C. Kralik ,  Tariq N. Faiz

    Inventor： John C. Kralik ,  Tariq N. Faiz

    IPC: G01J3/30

    CPC classification number: G01J3/30 ,  G01J3/02 ,  G01J3/0218 ,  G01J3/06 ,  G01J3/4406 ,  G01N21/6445 ,  G01N21/6452 ,  G01N2021/6421 ,  G01N2021/6439 ,  G01N2021/6471 ,  G01N2201/1241

    Abstract: A system for detecting a predetermined wavelength of light emitted from an area on the surface of a chemical array is provided. Aspects of the system include: a beam splitter for splitting emitted light into two or more light beams and a detector for detecting photons in each of the two produced light beams. Methods of detecting light using the subject system, programming for performing the subject methods and an array reader containing the subject system are also provided.

    Abstract translation: 提供一种用于检测从化学阵列表面上的区域发射的预定波长的光的系统。 该系统的方面包括：用于将发射的光分成两个或更多个光束的分束器和用于检测两个产生的光束中的每一个中的光子的检测器。 还提供了使用主题系统检测光的方法，用于执行主题方法的编程以及包含该主题系统的阵列阅读器。

    Inspection Systems and Methods for Extending the Detection Range of an Inspection System by Forcing the Photodetector into the Non-Linear Range
    32.
    发明申请
    Inspection Systems and Methods for Extending the Detection Range of an Inspection System by Forcing the Photodetector into the Non-Linear Range 有权
    检测系统和方法通过强制光检测器进入非线性范围来扩展检测系统的检测范围

    公开(公告)号：US20080291454A1

    公开(公告)日：2008-11-27

    申请号：US11751293

    申请日：2007-05-21

    Applicant: Zhongping Cai ,  Alexander Slobodov ,  Anatoly Romanovsky ,  Christian H. Wolters

    Inventor： Zhongping Cai ,  Alexander Slobodov ,  Anatoly Romanovsky ,  Christian H. Wolters

    IPC: G01N21/55

    CPC classification number: G01N21/9501 ,  G01N21/8851 ,  G01N2201/1241 ,  G01N2201/12769 ,  H01J43/18 ,  H01J43/30

    Abstract: An inspection system and method is provided herein for increasing the detection range of the inspection system. According to one embodiment, the inspection system may include a photodetector having a plurality of stages, which are adapted to convert light scattered from a specimen into an output signal, and a voltage divider network coupled for extending the detection range of the photodetector (and thus, the detection range of the inspection system) by saturating at least one of the stages. This forces the photodetector to operate in a non-linear manner. However, measurement inaccuracies are avoided by calibrating the photodetector output to remove any non-linear effects that may be created by intentionally saturating the at least one of the stages. In one example, a table of values may be generated during a calibration phase to convert the photodetector output into an actual amount of scattered light.

    Abstract translation: 本文提供了一种用于增加检查系统的检测范围的检查系统和方法。 根据一个实施例，检查系统可以包括具有多个级的光电检测器，其适于将从样本散射的光转换成输出信号，以及耦合的用于扩展光电检测器的检测范围的分压器网络 ，检查系统的检测范围）通过饱和至少一个级。 这迫使光电探测器以非线性方式工作。 然而，通过校准光电检测器输出以消除可能通过故意饱和至少一个级而产生的任何非线性效应来避免测量不准确。 在一个示例中，可以在校准阶段期间生成值表，以将光电检测器输出转换成实际的散射光量。

    Biopolymeric array scanners capable of automatic scale factor selection for a plurality of different dyes, and methods for making and using the same
    33.
    发明授权
    Biopolymeric array scanners capable of automatic scale factor selection for a plurality of different dyes, and methods for making and using the same 失效
    能够对多种不同染料进行自动比例因子选择的生物聚合物阵列扫描器及其制造和使用方法

    公开(公告)号：US07331511B2

    公开(公告)日：2008-02-19

    申请号：US10328109

    申请日：2002-12-23

    Applicant: John F. Corson ,  Scott D. Connell ,  Srinka Ghosh

    Inventor： John F. Corson ,  Scott D. Connell ,  Srinka Ghosh

    IPC: G06F17/00

    CPC classification number: G01N21/6452 ,  G01N21/6428 ,  G01N2201/1241

    Abstract: Biopolymeric array scanners that are capable of automatically selecting a dye specific scale factor to employ for a plurality of different dyes, as wells as methods for making and using the same, are provided. In many embodiments, the actual dye specific scale factor automatically selected by the scanner is one that is equal to a preset “master” scale factor, so that the scanner reads any supported dye using the same constant scale factor. The dye specific scale factor selection is typically made by reference to a collection of nominal scale factors for each member of the plurality of dyes. In using the subject scanners, a user simply inputs the one or more dyes being used in a given array assay, and the scanner automatically reads the array using an automatically chosen dye specific scale factor for the selected dyes. Also provided are methods of obtaining collections of nominal scale factors and computer readable mediums comprising the same. The subject invention finds use in a variety of different applications, including both genomics and proteomics applications.

    Abstract translation: 提供了能够自动选择染料比例因子以用于多种不同染料的生物聚合物阵列扫描仪，作为制备和使用它们的方法的孔。 在许多实施例中，由扫描仪自动选择的实际染料特异性比例因子等于预设的“主”比例因子，使得扫描器使用相同的恒定比例因子读取任何支持的染料。 染料比例因子选择通常参考多个染料中每个成员的标称比例因子的集合来进行。 在使用主题扫描仪时，用户只需输入在给定阵列测定中使用的一种或多种染料，并且扫描仪使用所选染料的自动选择的染料比例因子自动读取阵列。 还提供了获得标称比例因子的集合的方法以及包括其的计算机可读介质。 本发明可用于各种不同的应用，包括基因组学和蛋白质组学应用。

    Wide dynamic range chemical array reader
    34.
    发明申请
    Wide dynamic range chemical array reader 失效
    宽动态范围化学阵列阅读器

    公开(公告)号：US20070121110A1

    公开(公告)日：2007-05-31

    申请号：US11290100

    申请日：2005-11-29

    Applicant: John Kralik ,  Tariq Faiz

    Inventor： John Kralik ,  Tariq Faiz

    IPC: G01J3/30

    CPC classification number: G01J3/30 ,  G01J3/02 ,  G01J3/0218 ,  G01J3/06 ,  G01J3/4406 ,  G01N21/6445 ,  G01N21/6452 ,  G01N2021/6421 ,  G01N2021/6439 ,  G01N2021/6471 ,  G01N2201/1241

    Abstract: A system for detecting a predetermined wavelength of light emitted from an area on the surface of a chemical array is provided. Aspects of the system include: a beam splitter for splitting emitted light into two or more light beams and a detector for detecting photons in each of the two produced light beams. Methods of detecting light using the subject system, programming for performing the subject methods and an array reader containing the subject system are also provided.

    Abstract translation: 提供一种用于检测从化学阵列表面上的区域发射的预定波长的光的系统。 该系统的方面包括：用于将发射的光分成两个或更多个光束的分束器和用于检测两个产生的光束中的每一个中的光子的检测器。 还提供了使用主题系统检测光的方法，用于执行主题方法的编程以及包含该主题系统的阵列阅读器。

    Fluorimeter and detection method
    36.
    发明授权
    Fluorimeter and detection method 失效
    荧光计和检测方法

    公开(公告)号：US5894347A

    公开(公告)日：1999-04-13

    申请号：US75700

    申请日：1998-05-11

    Applicant: Stuart Gilmour MacDonald

    Inventor： Stuart Gilmour MacDonald

    IPC: C12Q1/68 ,  G01J3/10 ,  G01N21/64 ,  G01N21/75

    CPC classification number: G01N21/64 ,  G01J3/10 ,  G01N21/645 ,  G01N2201/0696 ,  G01N2201/1241

    Abstract: A method and fluorimeter for flashing a target at several different levels for detection of fluorescence by a PMT without blinding the PMT at the highest level. Two lamps are provided each of which is powered to flash at two different levels that are staged in energy from the lowest of four to the highest of four levels, and a shutter is provided to close off the PMT from exposure when an acceptable, detectable level of fluorescence is detected by the PMT.

    Abstract translation: 一种用于在几个不同的水平闪烁目标的方法和荧光计，用于通过PMT检测荧光，而不会使最高水平的PMT发生眩晕。 提供两个灯，每个灯被供电以两个不同的电平闪光，这两个电平从四个电平中的最低到四个电平的能量分级，并且当可接受的可检测电平提供快门以关闭PMT以防曝光 的荧光被PMT检测到。

    Real-time soil organic matter sensor
    37.
    发明授权
    Real-time soil organic matter sensor 失效
    实时土壤有机物传感器

    公开(公告)号：US5044756A

    公开(公告)日：1991-09-03

    申请号：US325698

    申请日：1989-03-13

    Applicant: Lawrence D. Gaultney ,  George E. Van Scoyoc ,  Darrell G. Schulze ,  Jason L. Shonk

    Inventor： Lawrence D. Gaultney ,  George E. Van Scoyoc ,  Darrell G. Schulze ,  Jason L. Shonk

    IPC: G01N21/47 ,  G01N21/85 ,  G01N33/24

    CPC classification number: G01N21/8507 ,  G01N21/4738 ,  G01N33/24 ,  G01N2021/855 ,  G01N2201/0216 ,  G01N2201/0621 ,  G01N2201/069 ,  G01N2201/1241

    Abstract: An apparatus for attachment to a vehicle for sensing the organic matter content of soil at a soil scene as it is moved through the soil by the vehicle has a probe including a housing, a light source and a light sensor. The light sensor senses the light reflected from the soil scene and produces an output signal which is related to the organic matter content of the soil at the soil scene. The housing is attached to the vehicle so that as it is moved through the soil the soil scene that is observed by the light sensor is beneath the surface of the surrounding soil and the housing shields the soil scene from ambient light. The apparatus also includes a processor which processes the signal from the light sensor using data predetermined from a particular landscape which includes the soil to be sensed.

    Abstract translation: 一种用于附接到车辆的装置，用于感测土壤场面当土壤通过车辆移动时的土壤的有机物含量，其具有包括壳体，光源和光传感器的探针。 光传感器感测从土壤场景反射的光，并产生与土壤场面土壤有机质含量有关的输出信号。 外壳附着在车辆上，使得当它被移动通过土壤时，由光传感器观察到的土壤场景在周围土壤的表面之下，并且外壳将土壤场景遮蔽环境光。 该装置还包括处理器，其使用从包括要感测的土壤的特定景观预定的数据处理来自光传感器的信号。

    Phase fraction measurement using light source adjusted in discrete steps
    38.
    发明授权
    Phase fraction measurement using light source adjusted in discrete steps 有权

    公开(公告)号：US09995725B2

    公开(公告)日：2018-06-12

    申请号：US15194853

    申请日：2016-06-28

    Applicant: SCHLUMBERGER TECHNOLOGY CORPORATION

    Inventor： Arifin Arifin ,  Cheng-Gang Xie

    IPC: G01N33/28 ,  G01N21/31 ,  G01F1/74

    CPC classification number: G01N33/2823 ,  G01F1/7086 ,  G01F1/74 ,  G01N21/314 ,  G01N21/359 ,  G01N21/532 ,  G01N2201/0694 ,  G01N2201/1241

    Abstract: Disclosed herein is an apparatus including a structure containing a multiphase fluid and having a transparent window. A collimated light source emits light through the transparent window structure at a wavelength at which a component of a desired phase of the multiphase fluid is absorptive. A photodetector is positioned such that the emitted light passes through the multiphase fluid in the structure and out through the transparent window structure to impinge upon the photodetector. The photodetector has an actual dynamic range for light detection. Processing circuitry adjusts a power of the collimated light source in a series of steps dependent upon a relationship between an output level of the photodetector and a threshold to cause measurement of the emitted light over an effective dynamic range greater than the actual dynamic range. Properties of the multiphase fluid are determined as a function of the measured emitted light.

Patent Agency Ranking