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    In vivo use of water absorbent polymers
    37.
    发明授权
    In vivo use of water absorbent polymers 失效
    体内使用吸水性聚合物

    公开(公告)号：US08263112B2

    公开(公告)日：2012-09-11

    申请号：US10840112

    申请日：2004-05-06

    Applicant: Jaime Simon ,  Alan D. Strickland

    Inventor： Jaime Simon ,  Alan D. Strickland

    IPC: A61K9/16

    CPC classification number: A61K31/78 ,  A61K9/00 ,  A61K9/1635 ,  A61K9/5073 ,  A61K31/715 ,  A61K31/716 ,  A61K31/74 ,  A61K47/32

    Abstract: The subject invention is a method and material for removing fluid from the intestinal tract of a host and may be useful in treating animals or human patients suffering from fluid overload states. In one embodiment, the subject method involves ingesting an enterically coated non-systemic, non-toxic, non-digestible, water absorbing polymer which absorbs fluid while passing through the intestinal tract. The polymer is excreted in the feces wherein the polymer and absorbed fluid is removed from the body. Preferred polymers include super absorbent acrylic acid polymers, preferably provided in bead form. The polymers may include functional groups for selectively removing blood borne waste products, e.g. urea, from the G.I. tract.

    Abstract translation: 本发明是用于从宿主的肠道中除去流体的方法和材料，并且可用于治疗患有流体过载状态的动物或人类患者。 在一个实施方案中，本发明方法涉及摄取肠道内涂覆的非全身性，无毒性，不可消化的吸水聚合物，其在通过肠道时吸收流体。 聚合物在粪便中排出，其中聚合物和吸收的流体从身体移除。 优选的聚合物包括优选以珠粒形式提供的超吸收性丙烯酸聚合物。 聚合物可以包括用于选择性地去除血液传播的废物的功能基团，例如。 尿素，来自G.I. 道。

    INJECTABLE FILLER FOR PODIATRIC AND ORTHOPEDIC USES
    38.
    发明申请
    INJECTABLE FILLER FOR PODIATRIC AND ORTHOPEDIC USES 审中-公开
    用于牙科和正畸用途的注射灌肠器

    公开(公告)号：US20120207792A1

    公开(公告)日：2012-08-16

    申请号：US13349873

    申请日：2012-01-13

    Applicant: Ayman Boutros

    Inventor： Ayman Boutros

    IPC: A61K31/78 ,  A61K31/785 ,  A61K9/14 ,  A61P43/00 ,  A61P25/00

    CPC classification number: A61K31/78 ,  A61K9/0019 ,  A61K31/785

    Abstract: A podiatric filler composition comprising a pliable biocompatible material and a physiologically acceptable suspending agent. The podiatric filler compositions may be used in methods for treating fat pad atrophy, foot pain, plantar faciitis, metatarsalgia, injury, and rheumatoid arthritis.

    Abstract translation: 一种足部填充剂组合物，其包含柔韧的生物相容性材料和生理上可接受的悬浮剂。 足部填充剂组合物可用于治疗脂肪垫萎缩，足部疼痛，足底肌炎，跖痛，损伤和类风湿性关节炎的方法。

    COMBINATION THERAPY WITH GLATIRAMER ACETATE AND RASAGILINE FOR THE TREATMENT OF MULTIPLE SCLEROSIS
    40.
    发明申请
    COMBINATION THERAPY WITH GLATIRAMER ACETATE AND RASAGILINE FOR THE TREATMENT OF MULTIPLE SCLEROSIS 审中-公开
    用于治疗多发性硬化症的乙酰胆碱酯酶和RASAGILINE的联合治疗

    公开(公告)号：US20120027718A1

    公开(公告)日：2012-02-02

    申请号：US13198229

    申请日：2011-08-04

    Applicant: Rivka Kreitman ,  Liat Hayardeny ,  Ruth Levy ,  Eran Blaugrund

    Inventor： Rivka Kreitman ,  Liat Hayardeny ,  Ruth Levy ,  Eran Blaugrund

    IPC: A61K31/785 ,  A61P37/02 ,  A61P25/00

    CPC classification number: A61K31/78 ,  A61K31/135 ,  A61K31/137 ,  A61K31/785 ,  A61K38/02 ,  A61K45/06 ,  A61K2300/00

    Abstract: The subject invention provides a method of treating a subject afflicted with a form of multiple sclerosis comprising periodically administering to the subject an amount of glatiramer acetate and an amount of rasagiline or the pharmaceutically acceptable salt thereof, wherein the amounts when taken together are effective to alleviate a symptom of the form of multiple sclerosis in the subject so as to thereby treat the subject. The subject invention also provides a package comprising glatiramer acetate, rasagiline or the pharmaceutically acceptable salt thereof and instructions for use of the together to alleviate a symptom of a form of multiple sclerosis in a subject. The subject invention further provides a pharmaceutical combination comprising separate dosage forms of an amount of glatiramer acetate and an amount of rasagiline or the pharmaceutically acceptable salt thereof, which combination is useful to alleviate a symptom of a form of multiple sclerosis in a subject.

    Abstract translation: 本发明提供了治疗患有多发性硬化症形式的受试者的方法，其包括向受试者定期施用一定量的醋酸格拉司定和一定量的雷沙吉兰或其药学上可接受的盐，其中一起使用的量有效缓解 在受试者中多发性硬化形式的症状，从而治疗受试者。 本发明还提供了一种包含醋酸格拉默，雷沙吉兰或其药学上可接受的盐的包装，以及用于一起减轻受试者中多发性硬化症状的症状的说明书。 本发明进一步提供药物组合，其包含一定量的醋酸格拉司定的单独剂量形式和一定量的雷沙吉兰或其药学上可接受的盐，该组合可用于减轻受试者中多发性硬化形式的症状。

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