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公开(公告)号:US20190048097A1
公开(公告)日:2019-02-14
申请号:US16168503
申请日:2018-10-23
Applicant: Genentech, Inc.
Inventor: Robert F. Kelley , Daniel K. Kirchhofer , Joyce Lai , Chingwei V. Lee , Wei-Ching Liang , Michael T. Lipari , Kelly M. Loyet , Tao Sai , Menno Van Lookeren Campagne , Yan Wu , Germaine Fuh
CPC classification number: C07K16/40 , A61K39/3955 , A61K2039/507 , C07K2317/24 , C07K2317/34 , C07K2317/53 , C07K2317/55 , C07K2317/76 , C07K2317/92 , C07K2317/94
Abstract: The present invention provides anti-HtrA1 antibodies (including bispecific anti-HtrA1 anti-Factor D antibodies) and methods of making and using the same, for example, in methods of treating HtrA1-associated disorders, ocular disorders, and/or complement-associated disorders.
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公开(公告)号:US10059768B2
公开(公告)日:2018-08-28
申请号:US14851003
申请日:2015-09-11
Applicant: Genentech, Inc.
Inventor: Steven R. Leong , Andrew Polson , Paul Polakis , Yan Wu , Wei-Ching Liang , Ron Firestein
IPC: C07K16/28 , C07K16/30 , A61K31/404 , A61K31/5517 , A61K31/706 , A61K38/05 , G01N33/574 , A61K47/68
CPC classification number: C07K16/2827 , A61K31/404 , A61K31/5517 , A61K31/706 , A61K38/05 , A61K47/6803 , A61K47/6809 , A61K47/6855 , A61K47/6869 , A61K2039/505 , C07K16/3015 , C07K16/3069 , C07K2317/21 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/565 , C07K2317/567 , C07K2317/73 , C07K2317/77 , C07K2317/92 , G01N33/57492
Abstract: The invention provides anti-B7-H4 antibodies and immunoconjugates and methods of using the same.
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公开(公告)号:US20160159910A1
公开(公告)日:2016-06-09
申请号:US14851003
申请日:2015-09-11
Applicant: GENENTECH, INC.
Inventor: Steven R. Leong , Andrew Polson , Paul Polakis , Yan Wu , Wei-Ching Liang , Ron Firestein
IPC: C07K16/28 , A61K31/5517 , A61K31/706 , G01N33/574 , A61K47/48 , C07K16/22 , A61K51/10 , A61K38/05 , A61K31/404
CPC classification number: C07K16/2827 , A61K31/404 , A61K31/5517 , A61K31/706 , A61K38/05 , A61K47/6803 , A61K47/6809 , A61K47/6855 , A61K47/6869 , A61K2039/505 , C07K16/3015 , C07K16/3069 , C07K2317/21 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/565 , C07K2317/567 , C07K2317/73 , C07K2317/77 , C07K2317/92 , G01N33/57492
Abstract: The invention provides anti-B7-H4 antibodies and immunoconjugates and methods of using the same.
Abstract translation: 本发明提供抗B7-H4抗体和免疫缀合物及其使用方法。
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公开(公告)号:US20160017040A1
公开(公告)日:2016-01-21
申请号:US14773334
申请日:2014-03-13
Applicant: GENENTECH, INC.
Inventor: Steven R. Leong , Andrew Polson , Paul Polakis , Yan Wu , Wei-Ching Liang , Ron Firestein
IPC: C07K16/28 , A61K47/48 , G01N33/569 , A61K39/395 , A61K51/10 , C07K16/30 , A61K38/08
CPC classification number: C07K16/2827 , A61K38/08 , A61K39/39558 , A61K47/65 , A61K47/6801 , A61K47/6809 , A61K47/6849 , A61K47/6855 , A61K51/1027 , A61K51/1051 , A61K2039/505 , C07K16/3015 , C07K2317/24 , C07K2317/33 , C07K2317/56 , C07K2317/73 , C07K2317/77 , C07K2317/92 , G01N33/56972
Abstract: The disclosure provides anti-B7-H4 antibodies and immunoconjugates and methods of using the same.
Abstract translation: 本公开提供抗B7-H4抗体和免疫缀合物及其使用方法。
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公开(公告)号:US09175089B2
公开(公告)日:2015-11-03
申请号:US13853620
申请日:2013-03-29
Applicant: GENENTECH INC.
Inventor: Jo-Anne Hongo , Weiguang Mao , Paul Polakis , Andrew Polson , Rajesh Vij , Yan Wu , Wei-Ching Liang
CPC classification number: C07K16/28 , A61K47/6803 , A61K47/6809 , A61K47/6817 , A61K47/6849 , A61K47/6859 , A61K47/6863 , A61K2039/505 , C07K16/30 , C07K16/3046 , C07K2317/24 , C07K2317/33 , C07K2317/73 , C07K2317/92 , G01N33/6893
Abstract: The invention provides anti-LgR5 antibodies and immunoconjugates and methods of using the same.
Abstract translation: 本发明提供抗LgR5抗体和免疫缀合物及其使用方法。
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36.Anti-CD22 antibodies and immunoconjugates and methods of use 有权
Title translation: 抗CD22抗体和免疫缀合物及其使用方法公开(公告)号:US08968741B2
公开(公告)日:2015-03-03
申请号:US13760751
申请日:2013-02-06
Applicant: Genentech, Inc.
Inventor: Allen J. Ebens , Alane M. Gray , Wei-Ching Liang , Yan Wu , Shang-Fan Yu
IPC: C07K16/28 , A61K47/48 , C07K16/30 , A61K39/395 , A61K45/06
CPC classification number: C07K16/3061 , A61K39/39558 , A61K45/06 , A61K47/6803 , A61K47/6849 , A61K47/6855 , C07K16/2803 , C07K16/2896 , C07K2317/24 , C07K2317/56 , C07K2317/77 , C07K2317/92
Abstract: Anti-CD22 antibodies and immunoconjugates thereof are provided. Methods of using anti-CD22 antibodies and immunoconjugates thereof are provided.
Abstract translation: 提供抗CD22抗体及其免疫偶联物。 提供了使用抗CD22抗体及其免疫偶联物的方法。
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公开(公告)号:US11919948B2
公开(公告)日:2024-03-05
申请号:US17205663
申请日:2021-03-18
Applicant: Genentech, Inc.
Inventor: Wei-Ching Liang , Joseph R. Arron , Daryle Depianto , Wendy Green Halpern , WeiYu Lin , Patrick J. Lupardus , Thirumalai Rajan Ramalingam , Dhaya Seshasayee , Tianhe Sun , Tulika Tyagi , Jia Wu , Yan Wu , Jian Ping Yin
IPC: C07K16/22 , A61K39/00 , A61K39/395 , A61P11/00 , C07K16/46
CPC classification number: C07K16/22 , A61P11/00 , C07K16/464 , A61K39/39533 , A61K39/39566 , A61K2039/505 , C07K2317/24 , C07K2317/31 , C07K2317/41 , C07K2317/565 , C07K2317/76 , C07K2317/92
Abstract: The invention provides isoform-selective anti-TGFβ antibodies and methods of using the same. In particular, isoform-selective anti-TGFβ2, anti-TGFβ3, and anti-TGFβ2/3 monoclonal antibodies are provided, e.g., for the treatment of fibrosis and other TGFβ-related disorders.
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公开(公告)号:US20190241663A1
公开(公告)日:2019-08-08
申请号:US16167000
申请日:2018-10-22
Applicant: Genentech, Inc.
Inventor: Steven R. Leong , Andrew Polson , Paul Polakis , Yan Wu , Wei-Ching Liang , Ron Firestein
IPC: C07K16/28 , A61K47/68 , C07K16/30 , A61K51/10 , G01N33/569 , A61K39/395 , A61K38/08 , A61K47/65
CPC classification number: C07K16/2827 , A61K38/08 , A61K39/39558 , A61K47/65 , A61K47/6801 , A61K47/6809 , A61K47/6849 , A61K47/6855 , A61K51/1027 , A61K51/1051 , A61K2039/505 , C07K16/3015 , C07K2317/24 , C07K2317/33 , C07K2317/56 , C07K2317/73 , C07K2317/77 , C07K2317/92 , G01N33/56972
Abstract: The invention provides anti-B7-H4 antibodies and immunoconjugates and methods of using the same.
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公开(公告)号:US10005848B2
公开(公告)日:2018-06-26
申请号:US14725412
申请日:2015-05-29
Applicant: Genentech, Inc.
Inventor: Jackson G Egen , Jo-Anne Hongo , Steven Kauder , Robert A Lazarus , Lydia Santell , Yan Wu , Meredith Hazen , Wei-Ching Liang
IPC: C07K16/40 , C07K14/705 , C07K16/28 , C07K14/52 , C12Q1/68 , G01N33/74 , C12Q1/6883 , A61K39/00
CPC classification number: C07K16/40 , A61K2039/505 , C07K14/52 , C07K14/70596 , C07K16/2863 , C07K2317/55 , C07K2317/74 , C07K2317/75 , C07K2317/76 , C07K2317/92 , C07K2319/30 , C12Q1/6883 , C12Q2600/106 , C12Q2600/156 , G01N33/74 , G01N2333/71 , G01N2333/912 , G01N2800/065 , G01N2800/20 , G01N2800/52
Abstract: This invention relates to RON compositions, in particular RON composition comprising a RON agonist, and methods of using the compositions for the treatment of diseases. The invention also relates to diagnosis of RON-associated or MSP-associated diseases.
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公开(公告)号:US20180044420A1
公开(公告)日:2018-02-15
申请号:US15657471
申请日:2017-07-24
Applicant: Genentech, Inc.
Inventor: Bing Zheng , Andrew Polson , Cecilia Chiu , Wei-Ching Liang , Yan Wu
IPC: C07K16/28 , A61K47/68 , A61K51/10 , A61K31/706 , G01N33/574 , C07K16/30 , A61K31/5517
CPC classification number: C07K16/2851 , A61K31/5517 , A61K31/706 , A61K47/68 , A61K47/6817 , A61K47/6867 , A61K47/6889 , A61K51/1069 , A61K51/1093 , C07K16/3061 , C07K2317/14 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/52 , C07K2317/76 , C07K2317/77 , C07K2317/92 , C07K2317/94 , G01N33/57426 , G01N2333/7056
Abstract: The invention provides anti-CLL-1 antibodies and immunoconjugates and methods of using the same.
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