公开(公告)号：US10005848B2

公开(公告)日：2018-06-26

申请号：US14725412

申请日：2015-05-29

Applicant: Genentech, Inc.

Inventor： Jackson G Egen ,  Jo-Anne Hongo ,  Steven Kauder ,  Robert A Lazarus ,  Lydia Santell ,  Yan Wu ,  Meredith Hazen ,  Wei-Ching Liang

IPC: C07K16/40 ,  C07K14/705 ,  C07K16/28 ,  C07K14/52 ,  C12Q1/68 ,  G01N33/74 ,  C12Q1/6883 ,  A61K39/00

CPC classification number: C07K16/40 ,  A61K2039/505 ,  C07K14/52 ,  C07K14/70596 ,  C07K16/2863 ,  C07K2317/55 ,  C07K2317/74 ,  C07K2317/75 ,  C07K2317/76 ,  C07K2317/92 ,  C07K2319/30 ,  C12Q1/6883 ,  C12Q2600/106 ,  C12Q2600/156 ,  G01N33/74 ,  G01N2333/71 ,  G01N2333/912 ,  G01N2800/065 ,  G01N2800/20 ,  G01N2800/52

Abstract: This invention relates to RON compositions, in particular RON composition comprising a RON agonist, and methods of using the compositions for the treatment of diseases. The invention also relates to diagnosis of RON-associated or MSP-associated diseases.