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    Container visual inspection assembly and method
    31.
    发明授权
    Container visual inspection assembly and method 有权

    公开(公告)号：US12169177B2

    公开(公告)日：2024-12-17

    申请号：US17786742

    申请日：2020-12-17

    Applicant: AMGEN INC.

    Inventor： Graham F. Milne ,  Dmitry Fradkin

    IPC: G01N21/88 ,  G01N21/90 ,  G02B5/30

    Abstract: Assemblies (10), devices, and methods are described herein that allow an examiner to inspect a container (12) of liquid product (14) through a bottom wall (18) of the container using a line-of-sight diversion member (28, e.g. beam splitter, mirror or prism). In some forms, the assemblies described herein can be provided with mounts and connecting arms to couple the devices to inspection booths.

    Anti-Sclerostin Antibodies and Their Use to Treat Bone Disorders as Part of a Regimen
    32.
    发明申请
    Anti-Sclerostin Antibodies and Their Use to Treat Bone Disorders as Part of a Regimen 有权

    公开(公告)号：US20240400664A1

    公开(公告)日：2024-12-05

    申请号：US18514269

    申请日：2023-11-20

    Applicant: AMGEN INC. ,  UCB PAHRMA S.A.

    Inventor： Martyn K. Robinson ,  Michael S. Ominsky ,  Xiaodong Li ,  Hua Zhu Ke

    IPC: C07K16/22 ,  A61K39/00 ,  A61K39/395 ,  A61K45/06 ,  A61P19/08 ,  A61P19/10

    Abstract: The invention relates to the treatment of bone disorders. In particular, the invention provides an approach involving administration of a high initial dose or doses of an sclerostin antibody to bring about a rapid increase in bone formation, followed by administration of lowers doses of the antibody to give a sustained lower rate of bone formation after the initial burst of bone formation. The invention also provides an approach involving decreasing dosing frequency with such an antibody to control bone formation. The approaches may be used in particular in those subjects who would benefit most from such an initial rapid burst of bone formation. Examples of such subjects include subjects who have been recently diagnosed or are experiencing severe symptoms of the disorder, as well as those subjects who have been administered a different treatment for the bone disorder which is proving ineffective. The approaches may be used in combination with each other.

    INSERTION MECHANISM FOR DRUG DELIVERY DEVICE
    33.
    发明申请
    INSERTION MECHANISM FOR DRUG DELIVERY DEVICE 有权

    公开(公告)号：US20240382673A1

    公开(公告)日：2024-11-21

    申请号：US18642384

    申请日：2024-04-22

    Applicant: AMGEN INC.

    Inventor： Adam B. McCullough ,  Erich Coiner ,  Alan D. Payne

    IPC: A61M5/142

    Abstract: An insertion mechanism for a drug delivery device including a trocar, a housing, and a manifold in fluid communication with a fluid pathway connector and movable relative to the housing between a first manifold position adjacent to a proximal end of the housing and a second manifold position adjacent to a distal end of the housing. A hub carrying the trocar or hollow delivery needle is removably connected to the manifold, the hub being movable relative to the housing between a first hub position adjacent to the proximal end of the housing and a second hub position adjacent to the distal end of the housing. A power source is configured to generate rotational motion. A motion conversion mechanism operatively connects the power source and the hub, and is configured to convert the rotational motion into linear motion of the hub.

    Packaging label
    36.
    发明授权
    Packaging label 有权

    公开(公告)号：US12136359B2

    公开(公告)日：2024-11-05

    申请号：US17916124

    申请日：2021-03-30

    Applicant: AMGEN INC.

    Inventor： Diogo Ferreira

    IPC: G09F3/02

    Abstract: A carton closure label is provided. The carton closure includes a first layer having a first adhesion value and a perforated portion extending at least substantially across a dimension of the first layer. The carton closure also includes a second layer removably coupled with the first layer, the second layer having a second adhesion value that is less than the first adhesion value.

    Handheld drug delivery device
    39.
    外观设计
    Handheld drug delivery device 有权

    公开(公告)号：USD1049367S1

    公开(公告)日：2024-10-29

    申请号：US29909619

    申请日：2023-08-08

    Applicant: AMGEN INC.

    Designer： Jakob Halkjaer Kvist ,  Joshua Jay Dudman

    Abstract: FIG. 1 is a perspective view showing a new design for a handheld drug delivery device with its needle shield in an extended position;
    FIG. 2 is a front view of the handheld drug delivery device of FIG. 1;
    FIG. 3 is a rear view of the handheld drug delivery device of FIG. 1;
    FIG. 4 is a right-side view of the handheld drug delivery device of FIG. 1;
    FIG. 5 is a left-side view of the handheld drug delivery device of FIG. 1;
    FIG. 6 is a top view of the handheld drug delivery device of FIG. 1;
    FIG. 7 is a bottom view of the handheld drug delivery device of FIG. 1;
    FIG. 8 is a perspective view of the handheld drug delivery device of FIG. 1 with its needle shield in a retracted position;
    FIG. 9 is a front view of the handheld drug delivery device of FIG. 8;
    FIG. 10 is a rear view of the handheld drug delivery device of FIG. 8;
    FIG. 11 is a right-side view of the handheld drug delivery device of FIG. 8;
    FIG. 12 is a left-side view of the handheld drug delivery device of FIG. 8;
    FIG. 13 is a top view of the handheld drug delivery device of FIG. 8;
    FIG. 14 is a bottom view of the handheld drug delivery device of FIG. 8;
    FIG. 15 is a perspective view showing a new design for a handheld drug delivery device with its needle shield in an extended position;
    FIG. 16 is a front view of the handheld drug delivery device of FIG. 15;
    FIG. 17 is a rear view of the handheld drug delivery device of FIG. 15;
    FIG. 18 is a right-side view of the handheld drug delivery device of FIG. 15;
    FIG. 19 is a left-side view of the handheld drug delivery device of FIG. 15;
    FIG. 20 is a top view of the handheld drug delivery device of FIG. 15;
    FIG. 21 is a bottom view of the handheld drug delivery device of FIG. 15;
    FIG. 22 is a perspective view of the handheld drug delivery device of FIG. 15 with its needle shield in a retracted position;
    FIG. 23 is a front view of the handheld drug delivery device of FIG. 22;
    FIG. 24 is a rear view of the handheld drug delivery device of FIG. 22;
    FIG. 25 is a right-side view of the handheld drug delivery device of FIG. 22;
    FIG. 26 is a left-side view of the handheld drug delivery device of FIG. 22;
    FIG. 27 is a top view of the handheld drug delivery device of FIG. 22; and,
    FIG. 28 is a bottom view of the handheld drug delivery device of FIG. 22.
    The broken lines are included for the purpose of illustrating portions of the design that form no part of the claimed design.

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