公开(公告)号：US20230015713A1

公开(公告)日：2023-01-19

申请号：US17934585

申请日：2022-09-23

Applicant: AMGEN INC.

Inventor： Zhe Huang ,  Jennitte LeAnn Stevens ,  Greg Flynn ,  Szilan Fodor ,  Mark Daris

IPC: C07K16/22 ,  A61K47/12 ,  A61K47/26

Abstract: The invention generally relates to anti-sclerostin antibodies having C-terminal modifications, and compositions comprising such antibodies.

公开(公告)号：US10202616B2

公开(公告)日：2019-02-12

申请号：US15519820

申请日：2015-10-14

Applicant: AMGEN INC.

Inventor： Mark Daris ,  Jennitte LeAnn Stevens ,  Chi-Ming Kevin Li ,  Huanying Ge

IPC: C12N15/85 ,  C12N9/88 ,  C12N9/02 ,  C07K14/47

Abstract: Disclosed are a recombinant expression vector and a host cell that contains the vector.

公开(公告)号：US20240352112A1

公开(公告)日：2024-10-24

申请号：US18525130

申请日：2023-11-30

Applicant: AMGEN INC.

Inventor： Zhe Huang ,  Jennitte LeAnn Stevens ,  Greg Flynn ,  Szilan Fodor ,  Mark Daris

IPC: C07K16/22 ,  A61K39/00 ,  A61K47/12 ,  A61K47/26

CPC classification number: C07K16/22 ,  A61K47/12 ,  A61K47/26 ,  A61K2039/505 ,  C07K2317/24

Abstract: The invention generally relates to anti-sclerostin antibodies having C-terminal modifications, and compositions comprising such antibodies.

公开(公告)号：US11858983B2

公开(公告)日：2024-01-02

申请号：US17934585

申请日：2022-09-23

Applicant: AMGEN INC.

Inventor： Zhe Huang ,  Jennitte LeAnn Stevens ,  Greg Flynn ,  Szilan Fodor ,  Mark Daris

IPC: A61K39/395 ,  C07K16/22 ,  A61K47/12 ,  A61K47/26 ,  A61K39/00

CPC classification number: C07K16/22 ,  A61K47/12 ,  A61K47/26 ,  A61K2039/505 ,  C07K2317/24

Abstract: The invention generally relates to anti-sclerostin antibodies having C-terminal modifications, and compositions comprising such antibodies.

公开(公告)号：US20210079082A1

公开(公告)日：2021-03-18

申请号：US16971590

申请日：2019-03-29

Applicant: AMGEN INC.

Inventor： Zhe Huang ,  Jennitte LeAnn Stevens ,  Greg Flynn ,  Szilan Fodor ,  Mark Daris

IPC: C07K16/22 ,  A61K47/12 ,  A61K47/26

Abstract: The invention generally relates to anti-sclerostin antibodies having C-terminal modifications, and compositions comprising such antibodies.

公开(公告)号：US11466079B2

公开(公告)日：2022-10-11

申请号：US16971590

申请日：2019-03-29

Applicant: AMGEN INC.

Inventor： Zhe Huang ,  Jennitte LeAnn Stevens ,  Greg Flynn ,  Szilan Fodor ,  Mark Daris

IPC: A61K39/395 ,  C07K16/22 ,  A61K47/12 ,  A61K47/26 ,  A61K39/00

Abstract: The invention generally relates to anti-sclerostin antibodies having C-terminal modifications, and compositions comprising such antibodies.