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公开(公告)号：US3728030A
公开(公告)日：1973-04-17
申请号：US3728030D
申请日：1970-06-22
Applicant: CARY INSTRUMENTS
Inventor： HAWES R
CPC classification number: G01J3/4537 , G01N21/19
Abstract: Fourier spectroscopy is used in the measurement of circular dichroism, the method involving the use of an interference polarization modulator which is characterized by production of negligible amplitude modulation in the absence of dichroism in the optical train that follows the modulator and in the detector. Either linear or circular dichroism in that region of the instrument will convert the polarization modulation into amplitude modulation. The polarization modulation is characterized by a different frequency for each wavelength of the radiation, thus the signals caused by the interaction of the radiation with dichroic sample may all be recorded simultaneously and may subsequently be ''''unscrambled'''' to derive the inverse Fourier transform of the ensemble of frequencies constituting the complete signal, and thus obtaining a transmission spectrum corresponding to the dichroism. The transmission spectrum in turn, in the case of the circular dichroism, may be converted into dichroism by dividing by the ordinary transmission spectrum (corresponding to ordinary absorption) which may be derived by ordinary Fourier spectroscopy.
Abstract translation: 傅立叶光谱法用于测量圆二色性，该方法涉及使用干涉偏振调制器，其特征在于在跟随调制器和检测器的光学列中不存在二色性的情况下产生可忽略的幅度调制。 仪器区域中的线性或圆二色性将将偏振调制转换为幅度调制。 偏振调制的特征在于对于辐射的每个波长的不同频率，因此由辐射与二向色样本的相互作用引起的信号可以同时被记录，并且可以随后被“解扰”以导出整体的逆傅立叶变换 的频率构成完整信号，从而获得对应于二色性的透射光谱。 在圆二色性的情况下，透射光谱又可以通过除以通过普通傅立叶光谱法得到的普通透射光谱（对应于普通吸收）而转换为二色性。
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公开(公告)号：US11668603B2
公开(公告)日：2023-06-06
申请号：US17339067
申请日：2021-06-04
Applicant: Rapid Phenotyping Pty Limited
Inventor： Selene Rodd-Routley
CPC classification number: G01J3/4537 , G01J3/14 , G01J9/02 , G01J2009/0284 , G01J2009/0288
Abstract: Embodiments are disclosed relating to a refractively-scanning interferometer comprising an aperture that receives an incident light beam at a receiving angle, a beam splitter configured to split the incident light beam into a first beam and a second beam, a first and a second reflector arranged to reflect the first beam and second beam, respectively, towards a combining optical element, and a refractive Optical Path Difference (rOPD) assembly interposed between the beam splitter and the first reflector, wherein the rOPD Assembly refracts the first light beam an even number of times with induced phase discrepancy being a vector sum of a first phase discrepancy induced by a first refraction and a second phase discrepancy induced by a second refraction, the rOPD Assembly being configured such that the first phase discrepancy is substantially opposite in direction to the second phase discrepancy, a portion of the first and second phase discrepancies cancelling one another out to decrease magnitude of the phase discrepancy.
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23.发明申请公开(公告)号：US20160084763A1
公开(公告)日：2016-03-24
申请号：US14890530
申请日：2014-05-13
Applicant: THE GENERAL HOSPITAL CORPORATION
Inventor： Johannes F. de Boer , Mattijs De Groot
IPC: G01N21/64
CPC classification number: G01N21/6458 , G01J3/0218 , G01J3/433 , G01J3/4406 , G01J3/453 , G01J3/4532 , G01J3/4537 , G01N21/4795 , G01N21/6486 , G01N2021/6463 , G01N2021/6484
Abstract: Systems and methods according to exemplary embodiments of the present disclosure can be provided that can efficiently detect the amplitude and phase of a spectral modulation. Such exemplary scheme can be combined with self-interference fluorescence to facilitate a highly sensitive depth localization of self-interfering radiation generated within a sample. The exemplary system and method can facilitate a scan-free depth sensitivity within the focal depth range for microscopy, endoscopy and nanoscopy.
Abstract translation: 可以提供根据本公开的示例性实施例的系统和方法，其可以有效地检测频谱调制的幅度和相位。 这种示例性方案可以与自身干涉荧光结合，以促进在样品内产生的自干扰辐射的高度敏感的深度定位。 示例性系统和方法可以在显微镜，内窥镜检查和纳米镜检查的焦深范围内促进无扫描深度灵敏度。
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公开(公告)号：US20140139924A1
公开(公告)日：2014-05-22
申请号：US14117396
申请日：2012-04-04
Applicant: Yoshihisa Warashina , Tomofumi Suzuki , Kohei Kasamori
Inventor： Yoshihisa Warashina , Tomofumi Suzuki , Kohei Kasamori
CPC classification number: G02B26/001 , G01B9/02051 , G01B9/02056 , G01J3/4535 , G01J3/4537 , G02B5/08 , G02B26/0833
Abstract: An optical module includes a first plate-shaped member having a light transmissive optical component which is formed by applying etching to a silicon region, and a second plate-shaped member having light reflective optical components (mirrors) for reflecting light transmitting through the light transmissive optical component. The first and second plate-shaped members are bonded to one another, and an optical path for light transmitting through the light transmissive optical component is along a component forming surface of the first plate-shaped member and a principal surface of the second plate-shaped member. Thereby, realizing an optical module in which it is possible to dispose the light reflective optical component and the light transmissive optical component close to one another, and a manufacturing method for the optical module.
Abstract translation: 光学模块包括具有通过对硅区域进行蚀刻形成的透光光学部件的第一板状部件和具有反射透过透光性的光的反射光学部件（反射镜）的第二板状部件 光学元件。 第一和第二板状构件彼此接合，并且用于透过透光性光学构件的光的光路沿着第一板状构件的构件形成表面，并且第二板状构件的主表面 会员。 由此，实现了可以将光反射型光学部件和透光性光学部件配置成彼此靠近的光学模块，以及光学模块的制造方法。
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公开(公告)号：US07480058B2
公开(公告)日：2009-01-20
申请号：US11656222
申请日：2007-01-19
Applicant: Yonghua Zhao , Jay Wei
Inventor： Yonghua Zhao , Jay Wei
IPC: G01B9/02
CPC classification number: G01B9/02044 , G01B9/02068 , G01B9/02087 , G01B9/02091 , G01J3/02 , G01J3/0289 , G01J3/45 , G01J3/4537
Abstract: A Fourier-domain optical coherence tomography (OCT) imager is presented. An OCT imager according to the present invention can have an auto-alignment process. The auto-alignment process automatically adjusts at least one optical component of a spectrometer of the imager so that the spectrometer is aligned during an imaging session. In addition to the auto-alignment process, OCT spectra are normalized for background spectra and for noise characteristics in order to provide a more accurate and clear OCT image.
Abstract translation: 提出了傅里叶域光学相干断层扫描（OCT）成像仪。 根据本发明的OCT成像器可以具有自动对准过程。 自动对准过程自动调整成像仪的光谱仪的至少一个光学组件，使得光谱仪在成像会话期间对准。 除了自动对准过程之外，为了提供更精确和更清晰的OCT图像，将OCT光谱归一化用于背景光谱和噪声特性。
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Patent Agency Ranking
公开(公告)号：US20070188765A1
公开(公告)日：2007-08-16
申请号：US11656222
申请日：2007-01-19
Applicant: Yonghua Zhao , Jay Wei
Inventor： Yonghua Zhao , Jay Wei
CPC classification number: G01B9/02044 , G01B9/02068 , G01B9/02087 , G01B9/02091 , G01J3/02 , G01J3/0289 , G01J3/45 , G01J3/4537
Abstract: A Fourier-domain optical coherence tomography (OCT) imager is presented. An OCT imager according to the present invention can have an auto-alignment process. The auto-alignment process automatically adjusts at least one optical component of a spectrometer of the imager so that the spectrometer is aligned during an imaging session. In addition to the auto-alignment process, OCT spectra are normalized for background spectra and for noise characteristics in order to provide a more accurate and clear OCT image.
Abstract translation: 提出了傅里叶域光学相干断层扫描（OCT）成像仪。 根据本发明的OCT成像器可以具有自动对准过程。 自动对准过程自动调整成像仪的光谱仪的至少一个光学组件，使得光谱仪在成像会话期间对准。 除了自动对准过程之外，为了提供更精确和更清晰的OCT图像，将OCT光谱归一化用于背景光谱和噪声特性。
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公开(公告)号：US06519040B1
公开(公告)日：2003-02-11
申请号：US09463796
申请日：2000-05-08
Applicant: William Bradshaw Amos
Inventor： William Bradshaw Amos
IPC: G01B902
CPC classification number: G01J3/4537 , G01J3/2823
Abstract: Fourier Transform Spectroscopy is performed using a birefringent device to vary path difference systematically for all regions of an image simultaneously, so that a separate interferogram is collected for each image region by combining intensity values in multiple images. The optics may allow a theoretical efficiency of 100% in light throughout.
Abstract translation: 使用双折射装置进行傅立叶变换光谱，以同时对图像的所有区域进行系统地改变路径差，从而通过组合多个图像中的强度值来为每个图像区域收集单独的干涉图。 光学元件可以使光线的理论效率达到100％。
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28.发明授权
公开(公告)号：US5313269A
公开(公告)日：1994-05-17
申请号：US82427
申请日：1993-06-28
Applicant: Fred H. Ponce , D. Warren Vidrine , Carlos H. Pareja
Inventor： Fred H. Ponce , D. Warren Vidrine , Carlos H. Pareja
CPC classification number: G01J3/4537
Abstract: A wedge-type interferometer is disclosed that is supported three-dimensionally by a cast inner shell, which contains a readily removable optical cartridge supporting the fixed and movable wedge-shape prisms of the interferometer. The fixed prism is supported from one side of a centerpiece of the cartridge while the movable prism is supported from the other side of the centerpiece for linear, scanning movement. The cartridge may be mechanically and optically aligned prior to insertion into the inner shell, and is easily removed if additional adjustments are required. A first corner cube mirror is supported by a plate secured to one wall of the inner shell and is aligned by micropositioner adjustment in the X-axis. A second corner cube mirror is supported by a plate secured to another wall of the inner shell and is aligned by micropositioner adjustment in the Y-axis. After alignment, the micrometers are removed, and the inner shell may be mounted in an outer, hermetically-sealed casting.
Abstract translation: 公开了一种楔形干涉仪，其由铸造内壳三维地支撑，该内壳包含支撑干涉仪的固定和可移动的楔形棱镜的容易移除的光学盒。 固定棱镜从墨盒的中心件的一侧支撑，而可动棱镜从中心件的另一侧被支撑，用于线性扫描运动。 在插入内壳之前，盒可以机械地和光学对准，并且如果需要额外的调整则容易去除。 第一个角立方反射镜由固定到内壳的一个壁上的板支撑，并通过X轴上的微定位器调节来对准。 第二个角立方反射镜由固定在内壳的另一个壁上的板支撑，并且通过在Y轴上的微定位器调节来对准。 在对准之后，去除微米，并且内壳可以安装在外部气密密封的铸件中。
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公开(公告)号：US4983041A
公开(公告)日：1991-01-08
申请号：US261855
申请日：1988-10-25
Applicant: Fumio Inaba
Inventor： Fumio Inaba
CPC classification number: G01J3/4537 , G01N21/76 , G01N21/763
Abstract: The present invention relates to a photo-counting Fourier spectroscopic apparatus which enables spectroscopic detection of extremely fine emission light seen in a living-body specimen or the like as bioluminescence, chemiluminescence, and fluoroescence from a living-body specimen. A light from a specimen which emits an extremely faint light is guided to an interferometer. A two-dimensional photon counter is used as an interference fringe detector. The two-dimensional photo counting device counts the number of incident photons to form an image. The obtained image is subjected to Fourier analysis to thereby obtain spectral information about the incident light. A double beam interferometer, a triangular common path interferometer, a Michelson interferometer and other interferometers are used.
Abstract translation: 本发明涉及一种能够从活体样本等中观察到的极细发光的生物发光，化学发光和荧光的光计数傅里叶分光装置。 来自发出非常微弱的光的样本的光被引导到干涉仪。 二维光子计数器用作干涉条纹检测器。 二维照片计数装置对入射光子数进行计数以形成图像。 对所获得的图像进行傅立叶分析，从而获得关于入射光的光谱信息。 使用双光束干涉仪，三角共通路径干涉仪，迈克尔逊干涉仪和其他干涉仪。
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公开(公告)号：US4265540A
公开(公告)日：1981-05-05
申请号：US80287
申请日：1979-10-01
Applicant: Walter M. Doyle
Inventor： Walter M. Doyle
CPC classification number: G01J3/4537
Abstract: A refractively scanned interferometer, of the type in which a wedge-shaped prism is moved across one interferometer arm for scanning purposes, in which a similarly shaped fixed prism in the other arm provides optical compensation to avoid aberration problems. The beamsplitter surface is on the fixed wedge-shaped prism, and the two wedge-shaped prisms constitute the only refractive elements in the interferometer arms.
Abstract translation: 折射扫描干涉仪，其中楔形棱镜通过一个干涉仪臂移动以用于扫描目的，其中另一个臂中的类似形状的固定棱镜提供光学补偿以避免像差问题。 分束器表面在固定的楔形棱镜上，两个楔形棱镜构成干涉仪臂中唯一的折射元件。
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