公开(公告)号：US07339170B2

公开(公告)日：2008-03-04

申请号：US10892740

申请日：2004-07-16

申请人： Shrenik Deliwala

发明人： Shrenik Deliwala

IPC分类号： G01J5/00

CPC分类号： G01J3/2823 ,  G01J3/02 ,  G01J3/021 ,  G01J3/0229 ,  G01J3/2889 ,  G01J3/433 ,  G01N21/211 ,  G01N2021/213

摘要： The invention features methods including: (i) modulating multiple components (e.g., different spatial regions, different wavelengths, or both) of electromagnetic (EM) radiation emerging from an object with different time-varying functions; (ii) measuring at least one time-varying signal derived from the modulated EM radiation emerging from the object; and (iii) reconstructing information about the object based on the measured signal and the time-varying functions.

摘要翻译： 本发明的特征在于方法包括：（i）调制从具有不同时变功能的物体出射的电磁（EM）辐射的多个分量（例如，不同的空间区域，不同的波长或两者） （ii）测量从所述对象中出现的经调制的EM辐射得到的至少一个时变信号; 和（iii）基于所测量的信号和随时间变化的功能重建关于对象的信息。

公开(公告)号：US20070285658A1

公开(公告)日：2007-12-13

申请号：US11452129

申请日：2006-06-12

申请人： Ricardo Claps ,  Bradley A. Smith

发明人： Ricardo Claps ,  Bradley A. Smith

IPC分类号： G01J3/44 ,  G01N21/65

CPC分类号： G01J3/44 ,  G01J3/0218 ,  G01J3/0227 ,  G01J3/1895 ,  G01J3/26 ,  G01J3/2889 ,  G01J3/32 ,  G01J2003/123 ,  G01N21/65

摘要： A new architecture for implementing a time-resolved Raman spectrometer is 2-3 orders of magnitude faster than current systems. The system additionally is compact, environmentally rugged, low cost and can detect multiple components of a sample simultaneously. In one embodiment, the invention employs a rotating optical switch to time multiplex an input signal through multiple bandpass filters and into a single optical detector which is electrically activated only when the filtered input light pulse is about to impact it.The combination of time-multiplexing the input signal through multiple optical filters and time-sequencing the optical detector enables the device to detect and analyze 2-3 orders of magnitude faster than current designs, processing spectra within milliseconds instead of seconds. The system can process multiple material samples (25+) simultaneously, instead of sequentially, and its mechanical ruggedness and simplicity enables using the system in harsh physical environments when traditional spectrometers can not be used reliably.

摘要翻译： 实现时间分辨拉曼光谱仪的新架构比现有系统快2-3个数量级。 该系统还具有结构紧凑，环境坚固，成本低，可同时检测样品的多个成分。 在一个实施例中，本发明采用旋转光学开关来将输入信号经过多个带通滤波器进行时间复用，并进入单个光学检测器，只有当滤波后的输入光脉冲即将影响时才能电激活。 通过多个光学滤波器对输入信号进行时间复用和对光学检测器进行时间排序的组合使得该器件能够比目前的设计更快地检测和分析2-3个数量级，在几毫秒而不是几秒内处理光谱。 该系统可以同时处理多个材料样品（25+），而不是依次加工，并且其机械坚固性和简单性使得在传统光谱仪不能可靠地使用恶劣的物理环境中使用该系统。

公开(公告)号：US07294842B2

公开(公告)日：2007-11-13

申请号：US10492003

申请日：2002-10-04

申请人： Wolfgang Biel ,  Alfred Scholl ,  Norbert Sandri ,  Gerd Telemann ,  Dietmar Brinkmann

发明人： Wolfgang Biel ,  Alfred Scholl ,  Norbert Sandri ,  Gerd Telemann ,  Dietmar Brinkmann

IPC分类号： G01T5/08

CPC分类号： G01J1/58 ,  G01J3/2803 ,  G01J3/2889

摘要： An apparatus for measuring the transport time of impurity particles in a plasma includes a spectrometer, a system for the spatially-resolving conversion into charge of light exiting the spectrometer, an integrator circuit for the spatially-resolving integration of the charge, as well as a display screen that presents the integrated charge as a series of spectral lines. The integrator circuit is assembled from discrete components. Thus, the transport of plasma impurities can be properly measured.

摘要翻译： 用于测量等离子体中的杂质颗粒的传输时间的装置包括光谱仪，用于空间分辨转换成离开光谱仪的光的电荷的系统，用于电荷的空间分辨一体化的积分器电路，以及 将集成电荷呈现为一系列光谱线的显示屏幕。 积分器电路由分立元件组装。 因此，可以适当地测量等离子体杂质的输送。

公开(公告)号：US20070085998A1

公开(公告)日：2007-04-19

申请号：US11369158

申请日：2006-03-06

申请人： Mordechai Brestel ,  Michael Gaft ,  Uzi Sharon

发明人： Mordechai Brestel ,  Michael Gaft ,  Uzi Sharon

IPC分类号： G01J3/44 ,  G01J3/30 ,  G01N21/65

CPC分类号： G01N21/6456 ,  G01J3/2889 ,  G01J3/44 ,  G01J3/4406 ,  G01N21/6408 ,  G01N21/65 ,  G01N21/658

摘要： A system for detecting controlled substances on an object including at least one laser for illuminating at least part of an object with laser energy and either a second harmonic detector or a luminescence controlled substance detector, or both. Additionally, a system also including a Raman scattering controlled substance detector is disclosed.

摘要翻译： 一种用于检测物体上的受控物质的系统，包括用于用激光能量照射至少一部分物体的至少一个激光器，以及二次谐波检测器或发光受控物质检测器或两者。 另外，还公开了一种还包括拉曼散射控制物质检测器的系统。

公开(公告)号：US20070046946A1

公开(公告)日：2007-03-01

申请号：US11153361

申请日：2005-06-16

申请人： Mitsuru Namiki

发明人： Mitsuru Namiki

IPC分类号： G01J3/45 ,  G01B9/02

CPC分类号： G01J3/2889 ,  G01J3/02 ,  G01J3/0208 ,  G01J3/453 ,  G02B21/16

摘要： An apparatus capable of observing an extremely small region and at the same time observing physical phenomena that occur in extremely short time spans on the order of, for example, several tens of picoseconds to femtoseconds, is provided. The apparatus includes a microscope, and a time-resolved spectroscopy unit, a first light-guiding unit for guiding light from the spectroscopy unit into the microscope, a second light-guiding unit for guiding the light from the microscope into the spectroscopy unit. The microscope includes an illuminating optical system and an observing optical system. The time-resolved spectroscopy unit includes an ultrashort optical pulse source, a beam splitter for splitting the ultrashort optical pulse into a reference beam and another beam, an optical system for generating a pump beam and a probe beam from the beam other than the reference beam, and an imaging device for time-resolved spectroscopy for capturing an interference pattern formed by the light guided by the second light-guiding unit and the reference beam. A two-dimensional lightwave conversion optical system is interposed between the second light-guiding unit and the imaging device.

摘要翻译： 提供了一种能够观察极小区域并同时观察在极短时间内发生的例如几十皮秒到飞秒的物理现象的装置。 该装置包括显微镜和时间分辨光谱单元，用于将来自光谱单元的光引导到显微镜中的第一导光单元，用于将来自显微镜的光引导到光谱单元中的第二导光单元。 显微镜包括照明光学系统和观察光学系统。 时间分辨光谱单元包括超短光脉冲源，用于将超短光脉冲分裂成参考光束的分束器和另一光束，用于从除了参考光束之外的光束产生泵浦光束和探测光束的光学系统 以及用于捕获由第二导光单元和参考光束引导的光形成的干涉图案的用于时间分辨光谱的成像装置。 二维光波转换光学系统介于第二导光单元和成像装置之间。

公开(公告)号：US20060262301A1

公开(公告)日：2006-11-23

申请号：US10545393

申请日：2004-02-13

申请人： Hirohiko Watanabe ,  Motoyuki Watanabe ,  Takayuki Inoue

发明人： Hirohiko Watanabe ,  Motoyuki Watanabe ,  Takayuki Inoue

IPC分类号： G01J3/30 ,  G01N21/64

CPC分类号： G01N21/6456 ,  G01J3/2803 ,  G01J3/2823 ,  G01J3/2889 ,  G01J3/4406 ,  G01J2003/2813 ,  G01J2003/282 ,  G01N21/645 ,  G01N2021/6417 ,  G01N2021/6423 ,  H04N5/3454 ,  H04N5/372

摘要： A fluorescence correlation spectroscopy analyzer 1 is equipped with an excitation light illuminating optical system 21, a fluorescence imaging optical system 22, a CCD camera 15, and a data analyzer 16. The excitation light illuminating optical system 21 illuminates excitation light onto a predetermined region of a measured sample S. The fluorescence imaging optical system 22 images the fluorescence generated at the measured sample S onto the photodetection surface of the CCD camera 15. The CCD camera 15 performs photoelectric conversion of the fluorescence made incident onto the photodetection surface in accordance with the respective pixels and outputs the charges generated by the photoelectric conversion as detection signals from an output terminal. The data analyzer 16 inputs the detection signals based on the charges generated at the pixels, among the pixels of the CCD camera 15, that belong to an analyzed pixel set and computes autocorrelation functions of the input detection signals according to each pixel. A fluorescence correlation spectroscopy analyzer, which is enabled to perform fluorescence correlation spectroscopy analysis on multiple points of a measured sample simultaneously and at high speed, is thus provided.

摘要翻译： 荧光相关光谱分析仪1配备有激发光照明光学系统21，荧光成像光学系统22，CCD照相机15和数据分析器16。 激发光照射光学系统21将激发光照射到测量样品S的预定区域上。荧光成像光学系统22将在测量样品S处产生的荧光图像到CCD照相机15的光电检测表面上。 CCD摄像机15根据各像素对入射到光检测面上的荧光进行光电转换，并将从光电转换产生的电荷作为检测信号从输出端子输出。 数据分析器16基于在CCD摄像机15的像素中产生的属于分析像素组的像素产生的电荷输入检测信号，并根据每个像素计算输入检测信号的自相关函数。 因此，提供了可以同时进行高速度地对多个点进行荧光相关光谱分析的荧光相关光谱分析仪。

公开(公告)号：US20060124863A1

公开(公告)日：2006-06-15

申请号：US10529653

申请日：2003-10-01

申请人： Tadashi Maruno ,  Fumio Iwase ,  Taiga Sato

发明人： Tadashi Maruno ,  Fumio Iwase ,  Taiga Sato

IPC分类号： H05B33/00

CPC分类号： G01J3/4406 ,  G01J3/2889 ,  G01N21/64 ,  H04N5/321

摘要： The invention relates to a fluorescence measuring apparatus to which a CCD camera capable of measuring fluorescent components emitted from a specimen corresponding to excitation pulse components emitted at regular intervals toward the specimen is applied. The fluorescence measuring apparatus has at least a CCD and a controller. The CCD includes photoelectric converters for implementing photoelectric conversion of the fluorescent components emitted from the specimen, and charge storage elements for storing and transferring charges resulting from the photoelectric conversion by the photoelectric converters. The controller outputs an electronic shutter signal for sweeping away the charge resulting from the photoelectric conversion by each photoelectric converter, a readout signal for reading the charge resulting from the photoelectric conversion, to the charge storage element, and a transfer signal for sequentially transferring the charge thus read. In particular, the controller outputs the electronic shutter signal corresponding to generation of each excitation pulse component, outputs the readout signal corresponding to output of the electronic shutter signal, and outputs the transfer signal per predetermined number of readout signals outputted.

摘要翻译： 本发明涉及一种荧光测量装置，其中应用能够测量从样本发射的荧光成分的CCD照相机，所述荧光成分对应于以规则间隔向样本发射的激发脉冲分量。 荧光测量装置至少具有CCD和控制器。 CCD包括用于实现从样本发射的荧光成分的光电转换的光电转换器，以及用于存储和转移由光电转换器进行光电转换的电荷的电荷存储元件。 控制器输出电子快门信号，用于扫除由光电转换器产生的光电转换所产生的电荷，用于读取由光电转换产生的电荷的读出信号到电荷存储元件，以及用于依次传送电荷的转印信号 因此阅读。 特别地，控制器输出与每个激励脉冲分量的产生相对应的电子快门信号，输出与电子快门信号的输出相对应的读出信号，并且输出每预定数量的读出信号的传送信号。

公开(公告)号：US20060119856A1

公开(公告)日：2006-06-08

申请号：US11293931

申请日：2005-12-05

申请人： Jun Koshoubu

发明人： Jun Koshoubu

IPC分类号： G01B9/02

CPC分类号： G01J3/453 ,  G01J3/2889 ,  G02B21/0096

摘要： A microscope comprising: a light sampler for collecting light from a measurement area of a sample; a multi-element detector having a plurality of photoelectric elements, for detecting the light collected by the light sampler, each photoelectric element corresponding to a minute measurement region in the measurement area with one-to-one correspondence; a Fourier transform spectrophotometer as a spectroscope; a data sampler for concurrently sampling intensity data sent from each photoelectric element of the multi-element detector at a timing determined by the Fourier transform spectrophotometer; and a data processor for obtaining time-resolved spectrum data for each minute measurement region according to temporally changed interference light data obtained by the data sampler.

摘要翻译： 一种显微镜，包括：用于收集来自样品的测量区域的光的光采样器; 具有多个光电元件的多元件检测器，用于检测由光采样器收集的光，每个光电元件对应于测量区域中的微小测量区域与一一对应; 傅里叶变换分光光度计作为分光镜; 数据采样器，用于在由傅里叶变换分光光度计确定的时刻同时采样从多元素检测器的每个光电元件发送的强度数据; 以及数据处理器，用于根据由数据采样器获得的时间上改变的干涉光数据，为每个微小测量区域获得时间分辨的光谱数据。

公开(公告)号：US20060092422A1

公开(公告)日：2006-05-04

申请号：US10522726

申请日：2003-07-30

申请人： Stephane Mottin

发明人： Stephane Mottin

IPC分类号： G01N21/59

CPC分类号： G01J3/2889 ,  G01N21/49 ,  G01N21/59

摘要： According to the invention, to analyse a non-limpid medium, this medium is lit by at least one light pulse, a spectral and temporal transmission image, in counting mode, is acquired from the lit medium, and the image and derivatives thereof are processed so as to acquire information about the non-limpid medium. The invention applies to the analysis of diffusing and absorbing media, for example milk.

摘要翻译： 根据本发明，为了分析不透明介质，从照明介质获取该介质中的至少一个光脉冲，光谱和时间透射图像，并且其图像及其衍生物被处理 以获取关于非清洁介质的信息。 本发明适用于扩散和吸收介质（例如牛奶）的分析。

公开(公告)号：US07002149B2

公开(公告)日：2006-02-21

申请号：US10496571

申请日：2002-11-25

申请人： Hidemi Shigekawa ,  Osamu Takeuchi ,  Mikio Yamashita ,  Ryuji Morita

发明人： Hidemi Shigekawa ,  Osamu Takeuchi ,  Mikio Yamashita ,  Ryuji Morita

IPC分类号： H01J37/00

CPC分类号： G01J3/433 ,  G01J3/2889 ,  G01J2001/4242 ,  G01N21/6408 ,  G01N21/6458 ,  G01N2021/6415 ,  G01Q30/02 ,  G01Q60/12 ,  Y10S977/85

摘要： Disclosed is a measuring apparatus for a physical phenomenon by photoexcitation, in particular a delay time modulated and time-resolved, scanning probe microscope apparatus providing an ultimate resolution both temporal and spatial. The apparatus comprises an ultrashort laser pulse generator (2); a delay time modulating circuit (6) which splits an ultrashort laser pulse (3) produced by the ultrashort laser pulse generator (2) into two and which also modulates a delay time td between the two ultrashort laser pulses (4 and 5) with a frequency (ω); a scanning probe microscope (7); and a lock-in detection unit (8) which performs lock-in detection with the delay time modulation frequency (ω) of a probe signal (11) from the scanning probe microscope (7). It can detect the delay time dependency of the probe signal (11) as its differential coefficient to the delay time, with no substantial influence from fluctuations in the intensity of ultrashort laser pulses (3) while preventing the probe apex (19) from thermal expansion and shrinkage by repeated irradiation with ultrashort laser pulses (3). A photoexcited physical phenomenon dependent on a delay time between ultrashort laser pulses can thus be measured at a temporal resolution in the order of femtoseconds and at a spatial resolution in the order of angstroms.

摘要翻译： 公开了一种通过光激发的物理现象的测量装置，特别是延迟时间调制和时间分辨的扫描探针显微镜装置，其提供了时间和空间上的最终分辨率。 该装置包括超短激光脉冲发生器（2）; 延迟时间调制电路（6），其将由超短激光脉冲发生器（2）产生的超短激光脉冲（3）分成两个，并且还调制两个超短激光器之间的延迟时间t 具有频率（ω）的脉冲（4和5）; 扫描探针显微镜（7）; 以及锁定检测单元（8），其利用来自扫描探针显微镜（7）的探测信号（11）的延迟时间调制频率（ω）执行锁定检测。 探测信号（11）的延迟时间依赖性可以作为其延迟时间的微分系数，而不会因为超短激光脉冲（3）的强度的波动带来实质的影响，同时防止探头顶点（19）的热膨胀 以及通过用超短激光脉冲（3）重复照射来收缩。 因此，依赖于超短激光脉冲之间的延迟时间的光激发物理现象可以以飞秒级的时间分辨率和以埃的空间分辨率测量。