公开(公告)号：US10346989B2

公开(公告)日：2019-07-09

申请号：US15535763

申请日：2015-12-11

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Jingping Xu ,  Kongkuo Lu ,  William Tao Shi ,  Christopher Stephen Hall

IPC: G06T7/38 ,  G06T7/20 ,  G06T7/246

Abstract: The invention relates to a method of calculating a displacement of an object of interest comprising a step of calculating (101) a displacement model of said object of interest from adjacent images of a set of pre-acquired images of said object of interest, said displacement model reflects the position of said object of interest along the time. The method is characterized in that the method further comprises the following. A step of determining (102) a first sub-set of images (S1) from said set of pre acquired images within one periodical time cycle of said set of pre-acquired images on the basis of the displacement model. A first step of identifying (103) a second sub-set of images (S2) from newly-acquired images, wherein images in said second sub-set of images (S2) are consecutive and have the same most similar image in said first sub-set of images (S1), wherein a first set of similarity levels is determined by comparing a given image in said newly acquired images with each image of said first sub-set of images (S1), and wherein said most similar image has the largest similarity level in said first set of similarity levels. A first step of selecting (104) a given image in said second sub-set of images (S2) as a first reference image (I1). A second step of identifying (105) a third sub-set of images (S3) from said newly-acquired images, wherein images in said third sub-set of images (S3) are consecutive and have the same most similar image in said first sub-set of images (S1), wherein a set of similarity levels is determined by comparing a given image in said newly acquired images with each image of said first sub-set of images (S1), and wherein said most similar image has the largest similarity level in said set of similarity levels. A second step of selecting (106) a given image in said third sub-set of images (S3) as a second reference image (I2). A step of calculating (107) the displacement between said second reference image (I2) and said first reference image (I1). The invention also relates to a corresponding system of displacement calculation.

公开(公告)号：US10265544B2

公开(公告)日：2019-04-23

申请号：US14411115

申请日：2013-06-18

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Shyam Bharat ,  Christopher Stephen Hall

IPC: A61B5/00 ,  A61N5/10 ,  A61B5/1455 ,  A61B5/026 ,  A61B8/08 ,  A61B34/30 ,  A61B5/145

Abstract: A system and method for perfusion imaging includes an imaging device (122) configured to collect perfusion information from a target area. A processing module (110) is configured to determine perfusion levels of the target area based on the perfusion information. A planning module (114) is configured to provide a treatment plan for the target area by correlating the perfusion levels with treatment activities for the target area, wherein the treatment activities are adjusted based upon characteristics of the perfusion levels in the target area.

公开(公告)号：US20140343571A1

公开(公告)日：2014-11-20

申请号：US14361943

申请日：2012-11-27

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Aleksandra Popovic ,  Haytham Elhawary ,  Christopher Stephen Hall

IPC: A61B19/00

CPC classification number: C07J43/003 ,  A61B1/0005 ,  A61B8/12 ,  A61B8/4218 ,  A61B34/30 ,  A61B90/361 ,  A61B2034/301 ,  A61B2090/3782 ,  A61B2090/3784 ,  A61K9/107 ,  A61K47/26 ,  A61K47/28 ,  C07J9/00 ,  C07J31/006 ,  C07J41/0061 ,  C07J51/00 ,  C07K1/145

Abstract: Systems and methods for surgical robotic guidance include a robotic system (124) having a robot (122) configured to pass to a target through a port (134). The robotic system includes a visual component (102) employed in guiding the robot along a path to a location. The location is defined in accordance with a position and orientation of the robot. An ultrasonic probe (125) is guided by the robot to the location to permit engagement of the probe to collect ultrasonic images at the location.

Abstract translation: 用于外科手术引导的系统和方法包括机器人系统（124），其具有被配置为通过端口（134）传递到目标的机器人（122）。 机器人系统包括用于沿着到达位置的路径引导机器人的视觉部件（102）。 该位置根据机器人的位置和方向来定义。 超声波探头（125）由机器人引导到位置，以允许探针接合以在该位置收集超声波图像。

公开(公告)号：US20140243737A1

公开(公告)日：2014-08-28

申请号：US14349496

申请日：2012-09-25

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Todd Nicholas Erpelding ,  Ralf Seip ,  Christopher Stephen Hall ,  Balasundar Iyyavu Raju

IPC: A61M37/00

CPC classification number: A61M37/0092 ,  A61B5/14546 ,  A61B5/4839 ,  A61B5/6805 ,  A61B6/032 ,  A61B6/037 ,  A61B8/08 ,  A61B8/4227 ,  A61M2037/0007

Abstract: Ultrasound mediated delivery (USMD), real-time quantitative feedback derived (S264) therefrom, and proceeding by the system based on the feedback all are, in some embodiments, operable automatically and without need for user intervention. USMD may occur in a clinical setting accompanied by assays (S276) or real-time feedback, or by means of a wearable device that, based on feedback, regulates USMD in real time. Optionally, the user is provided an indication (S281) as to progress or success, of a treatment. Electrodes (128) may be attached across tissue in which transient pores are produced via sonoporation in the USMD procedure, and in vivo measurement is taken of an electrical parameter responsive to permeability. Therapeutic agent (S202) may be administered after particles activated for sonoporation are cleared from the circulation, to avoid, when it might exist, adverse interaction between the particles and agent.

Abstract translation: 在一些实施例中，超声介导递送（USMD），从其导出的实时定量反馈（S264）以及由系统基于反馈进行的所有这些都是可自动操作的，而不需要用户干预。 USMD可能发生在伴随测定（S276）或实时反馈的临床设置中，或者通过基于反馈实时调节USMD的可穿戴设备发生。 可选地，向用户提供关于治疗的进展或成功的指示（S281）。 电极（128）可以穿过在USMD程序中经由声孔产生瞬时孔的组织，并且体内测量响应于渗透性的电参数。 治疗剂（S202）可以在用于进行超声波活化的颗粒从循环中清除之后施用，以避免在可能存在的情况下颗粒和试剂之间的不利相互作用。

公开(公告)号：US11617623B2

公开(公告)日：2023-04-04

申请号：US15110421

申请日：2015-01-04

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Christopher Stephen Hall ,  Bharat Ramachandran ,  Molly Lara Flexman ,  Aleksandra Popovic

IPC: A61B8/12 ,  A61B34/20 ,  A61B8/08 ,  A61B8/00 ,  A61B5/06 ,  A61B8/14 ,  G06T19/00 ,  G06T7/30 ,  G06T7/70 ,  A61B34/30

Abstract: A system for providing a perspective for a virtual image includes an intraoperative imaging system (110) having a transducer (146) configured to generate an image data set for a region. A shape sensing enabled device (102) is configured to have at least a portion of the shape sensing enabled device positioned relative to the region. The shape sensing enabled device has a coordinate system registered with a coordinate system of the intraoperative imaging system. An image generation module (148) is configured to render a virtual image (152) of at least a portion of the region using the image data set wherein the virtual image includes a vantage point relative to a position on the shape sensing enabled device.

公开(公告)号：US11583697B2

公开(公告)日：2023-02-21

申请号：US14424282

申请日：2013-08-15

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Jochen Kruecker ,  Shyam Bharat ,  Cynthia Ming-Fu Kung ,  Christopher Stephen Hall ,  Falk Uhlemann

IPC: A61B8/00 ,  A61N5/10 ,  A61B17/34 ,  A61B34/20 ,  A61B17/00

Abstract: A system with integrated tracking includes a procedure-specific hardware component (112 or 116) disposed at or near a region of interest. A field generator (114) is configured to generate a field with a field of view covering the region of interest. A mounting device (115) is connected to the field generator and is coupled to the procedure-specific hardware. The field generator is fixedly positioned by the mounting device to permit workflow access to the region of interest without interfering with the field generator and to provide a known position of the field generator relative to the region of interest. A tracking device (110) is configured to be inserted in or near the region of interest to be tracked within the field of view of the field generator to generate tracking data.

公开(公告)号：US20150216619A1

公开(公告)日：2015-08-06

申请号：US14424282

申请日：2013-08-15

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Jochen Kruecker ,  Shyam Bharat ,  Cynthia Ming-fu Kung ,  Christopher Stephen Hall ,  Falk Uhlemann

IPC: A61B19/00 ,  A61N5/10

CPC classification number: A61N5/1001 ,  A61B17/3403 ,  A61B34/20 ,  A61B2017/00274 ,  A61B2017/3411 ,  A61B2034/2051 ,  A61B2034/2072 ,  A61N5/1007 ,  A61N5/1049 ,  A61N2005/1012 ,  A61N2005/1051 ,  A61N2005/1058

Abstract: A system with integrated tracking includes a procedure-specific hardware component (112 or 116) disposed at or near a region of interest. A field generator (114) is configured to generate a field with a field of view covering the region of interest. A mounting device (115) is connected to the field generator and is coupled to the procedure-specific hardware. The field generator is fixedly positioned by the mounting device to permit workflow access to the region of interest without interfering with the field generator and to provide a known position of the field generator relative to the region of interest. A tracking device (110) is configured to be inserted in or near the region of interest to be tracked within the field of view of the field generator to generate tracking data.

Abstract translation: 具有集成跟踪的系统包括设置在感兴趣区域处或附近的特定于程序的硬件组件（112或116）。 场发生器（114）被配置为产生具有覆盖感兴趣区域的视场的场。 安装装置（115）连接到场发生器并且耦合到程序特定的硬件。 场发生器通过安装装置固定地定位，以允许工作流程进入感兴趣区域而不干扰场发生器，并提供现场发电机相对于感兴趣区域的已知位置。 跟踪装置（110）被配置为插入到场发生器的视野内要跟踪的感兴趣区域中或附近，以产生跟踪数据。

公开(公告)号：US20150150536A1

公开(公告)日：2015-06-04

申请号：US14403375

申请日：2013-05-27

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Bharat Ramachandran ,  Christopher Stephen Hall

IPC: A61B8/08 ,  A61B8/12 ,  A61B8/00 ,  A61B5/00

CPC classification number: A61B8/485 ,  A61B5/0051 ,  A61B5/0095 ,  A61B5/085 ,  A61B8/085 ,  A61B8/12 ,  A61B8/4444 ,  A61B8/445 ,  G01S7/52042 ,  G01S15/899

Abstract: A system for pulmonary elastography includes an ultrasound probe (120) configured to evaluate tissue of a target area by transmitting a signal and receiving a response. A contact device (126) is coupled to the ultrasound probe to provide contact between the ultrasound probe and the tissue. An image processing module (110) is configured to output one or more elastograms according to the response.

Abstract translation: 用于肺弹性成像的系统包括被配置为通过发送信号并接收响应来评估目标区域的组织的超声波探头（120）。 接触装置（126）耦合到超声波探头以提供超声波探针与组织之间的接触。 图像处理模块（110）被配置为根据响应输出一个或多个弹性图。

公开(公告)号：US20150146951A1

公开(公告)日：2015-05-28

申请号：US14402185

申请日：2013-05-23

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Lyubomir Georgiev Zagorchev ,  Stewart Young ,  Christopher Stephen Hall

IPC: G06T7/00

CPC classification number: G06T7/0012 ,  G01R33/5608 ,  G06T7/11 ,  G06T7/149 ,  G06T2207/10081 ,  G06T2207/10088 ,  G06T2207/10132 ,  G06T2207/20128 ,  G06T2207/30016

Abstract: A system and method for receiving a medical image, receiving an adaptation of a model of a physical structure, the adaptation relating to the medical image, determining an image quantity of the medical image at each of a plurality of vertices of the adaptation and aggregating the plurality of image quantities to determine an evaluation metric.

Abstract translation: 一种用于接收医学图像的系统和方法，接收物理结构的模型的适应，与医学图像相关的适应，在适应的多个顶点中的每一个上确定医学图像的图像量，并且聚合 多个图像量以确定评估度量。

公开(公告)号：US20140301618A1

公开(公告)日：2014-10-09

申请号：US14353776

申请日：2012-10-19

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Aleksandra Popovic ,  Haytham Elhawary ,  Christopher Stephen Hall

IPC: G06T3/00 ,  G06T7/00 ,  G06T19/00 ,  A61B1/00

CPC classification number: G06T3/0068 ,  A61B1/00009 ,  A61B34/30 ,  A61B90/37 ,  A61B2090/365 ,  A61B2090/367 ,  G06T7/0012 ,  G06T19/00 ,  G06T2207/10068 ,  G06T2207/30101

Abstract: An image registration system an endoscope (12) and an endoscope controller (22). In operation, the endoscope (12) generates an intra-operative endoscopic image (14) of a vessel tree (e.g., an arterial tree or a venous tree) within an anatomical region, and the endoscope controller (22) image registers the intra-operative endoscopic image (14) of the vessel tree to a pre-operative three-dimensional image (44) of the vessel tree within the anatomical region. The image registration includes an image matching of a graphical representation of each furcation of the vessel tree within the intra-operative endoscopic image (14) of the vessel tree to a graphical representation of each furcation of the vessel tree within the pre-operative three-dimensional image (44) of the vessel tree.

Abstract translation: 图像配准系统，内窥镜（12）和内窥镜控制器（22）。 在操作中，内窥镜（12）在解剖区域内生成血管树（例如动脉树或静脉树）的手术内窥镜图像（14），内窥镜控制器（22） 血管树的手术内窥镜图像（14）到解剖区域内的血管树的手术前三维图像（44）。 图像配准包括血管树的术中内窥镜图像（14）内的血管树的每个分叉的图形表示与术前三维血管内血管树的每个分叉的图形表示的图像匹配， 容器树的三维图像（44）。