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公开(公告)号:US10981987B2
公开(公告)日:2021-04-20
申请号:US15803495
申请日:2017-11-03
Applicant: GENENTECH, INC.
Inventor: Yvonne Chen , Mark Dennis , Kristi Elkins , Jagath Reddy Junutula , Andrew Polson , Bing Zheng
IPC: A61K51/00 , A61K39/395 , A61K39/40 , C07K16/28 , C07K16/30 , A61K51/10 , A61K47/68 , C07K16/00 , C12P21/08 , A61K39/00
Abstract: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
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公开(公告)号:US10556966B2
公开(公告)日:2020-02-11
申请号:US16170819
申请日:2018-10-25
Applicant: Genentech, Inc.
Inventor: Xiaocheng Chen , Mark Dennis , Jagath Reddy Junutula , Gail Lewis Phillips , Thomas Harden Pillow , Mark X. Sliwkowski
IPC: C07K16/32 , A61K47/68 , A61K39/395 , C07K16/28 , G01N33/574 , A61K31/5517 , A61K31/675 , A61K31/704 , A61K49/00 , C07K16/30
Abstract: The invention provides anti-HER2 antibodies and immunoconjugates and methods of using the same.
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公开(公告)号:US10022452B2
公开(公告)日:2018-07-17
申请号:US15486832
申请日:2017-04-13
Applicant: Genentech, Inc.
Inventor: Mark Dennis , Suzanna J. Scales , Susan D. Spencer , Yin Zhang
IPC: A61K51/10 , C07K16/30 , A61K31/7068 , A61K45/06 , A61K39/395 , A61K38/08 , A61K47/48 , A61K39/00
Abstract: The invention provides anti-mesothelin antibodies and immunoconjugates and methods of using the same.
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公开(公告)号:US20170274092A1
公开(公告)日:2017-09-28
申请号:US15438418
申请日:2017-02-21
Applicant: GENENTECH, INC.
Inventor: Xiaocheng Chen , Mark Dennis , Jagath Reddy Junutula , Gail Lewis Phillips , Thomas Harden Pillow , Mark X. Sliwkowski
IPC: A61K47/48 , C07K16/00 , A61K39/395 , C07K16/32 , A61K31/5517 , C07K19/00 , C07D487/16
CPC classification number: A61K31/5517 , A61K39/39558 , A61K47/6803 , A61K47/6855 , A61K47/6869 , C07K16/005 , C07K16/32 , C07K2317/24 , C07K2317/92
Abstract: The invention provides immunoconjugates comprising anti-HER2 antibodies and methods of using the same.
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公开(公告)号:US20140363873A1
公开(公告)日:2014-12-11
申请号:US14273308
申请日:2014-05-08
Applicant: Genentech, Inc.
Inventor: Mark Dennis , Bonnee Rubinfeld , Paul Polakis
IPC: C07K16/30
CPC classification number: C07K16/30 , A61K31/537 , A61K45/06 , A61K47/6803 , A61K47/6809 , A61K47/6813 , A61K47/6817 , A61K47/6849 , A61K47/6851 , A61K47/6857 , A61K47/6869 , A61K2039/505 , C07K16/18 , C07K16/28 , C07K16/3023 , C07K16/3069 , C07K2317/14 , C07K2317/24 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/73 , C07K2317/76 , C07K2317/77 , C07K2317/92 , G01N33/57423 , G01N33/57449 , G01N33/57492
Abstract: The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
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公开(公告)号:US08871911B2
公开(公告)日:2014-10-28
申请号:US13963286
申请日:2013-08-09
Applicant: Genentech, Inc.
Inventor: Mark Dennis , Bonnee Rubinfeld , Paul Polakis
CPC classification number: C07K16/30 , A61K31/537 , A61K45/06 , A61K47/6803 , A61K47/6809 , A61K47/6813 , A61K47/6817 , A61K47/6849 , A61K47/6851 , A61K47/6857 , A61K47/6869 , A61K2039/505 , C07K16/18 , C07K16/28 , C07K16/3023 , C07K16/3069 , C07K2317/14 , C07K2317/24 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/73 , C07K2317/76 , C07K2317/77 , C07K2317/92 , G01N33/57423 , G01N33/57449 , G01N33/57492
Abstract: The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
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公开(公告)号:US10544218B2
公开(公告)日:2020-01-28
申请号:US15349964
申请日:2016-11-11
Applicant: Genentech, Inc.
Inventor: Yvonne Chen , Mark Dennis , David Dornan , Kristi Elkins , Jagath Reddy Junutula , Andrew Polson , Bing Zheng
IPC: A61K39/395 , A61K39/40 , A61K39/42 , C07K16/28 , A61K38/05 , A61K31/537 , C07K16/30 , A61K51/10 , G01N33/574 , A61K45/06 , A61K47/68 , C07K16/00 , C12P21/08 , A61K39/00
Abstract: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
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公开(公告)号:US20190276550A9
公开(公告)日:2019-09-12
申请号:US13973669
申请日:2013-08-22
Applicant: Genentech, Inc.
Inventor: Yvonne Chen , Mark Dennis , David Dornan , Kristi Elkins , Jagath Reddy Junutula , Andrew Polson , Bing Zheng
IPC: C07K16/28 , A61K39/395 , A61K45/06
Abstract: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
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公开(公告)号:US20180362620A1
公开(公告)日:2018-12-20
申请号:US15821062
申请日:2017-11-22
Applicant: Genentech, Inc.
Inventor: Mark Dennis , Mary Mathieu
Abstract: The present invention relates to anti-Ebola virus envelope glycoprotein antibodies. The invention further relates to diagnostic methods which utilize the anti-Ebola virus glycoprotein antibodies and to pharmaceutical compositions which employ these antibodies therapeutically and prophylactically.
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公开(公告)号:US09803191B2
公开(公告)日:2017-10-31
申请号:US13934570
申请日:2013-07-03
Applicant: Genentech, Inc.
Inventor: Devin Tesar , Xiaocheng Chen , Mark Dennis , Isidro Hotzel
CPC classification number: C12N15/1037 , C07K16/00 , C07K2319/02 , C07K2319/40 , C07K2319/735 , C12N15/70 , C12N15/74 , C12N15/85 , C12N2820/10 , C12N2820/55 , C12N2820/85 , C12N2830/42 , C12N2830/55 , C12N2830/85 , C12P21/02
Abstract: The invention provides an expression and secretion system, and methods of using the same, for the expression and secretion of one fusion protein in prokaryotic cells and a second fusion protein in eukaryotic cells. Also provided herein are nucleic acid molecules, vectors and host cells comprising such vectors and nucleic acid molecules.
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