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    Confocal microscope
    21.
    发明授权
    Confocal microscope 失效
    共焦显微镜

    公开(公告)号：US5847867A

    公开(公告)日：1998-12-08

    申请号：US892380

    申请日：1997-07-14

    Applicant: Yumiko Sugiyama ,  Takeo Tanaami ,  Kenta Mikuriya ,  Katsumi Isozaki

    Inventor： Yumiko Sugiyama ,  Takeo Tanaami ,  Kenta Mikuriya ,  Katsumi Isozaki

    IPC: G02B21/00

    CPC classification number: G02B21/0044

    Abstract: A confocal microscope comprising a confocal laser scanner which rotates a Nipkow disk at high speed together with microlenses wherein a beam splitter of a plate type is disposed between two integrated disks, in each of which a plurality of microlenses and minute openings are arranged with the same pattern in an array, and wherein the axis of incident light is tilted by a significant angle to the vertical incident axis of the microlenses, so that the light axis shift generated by the plate beam splitter is cancelled and the incident light to the relevant microlense is caused to be focused to the corresponding minute opening thereby improving light use efficiency.

    Abstract translation: 一种共聚焦显微镜，其包括共聚焦激光扫描仪，该共聚焦激光扫描仪将Nipkow盘与微透镜一起高速旋转，其中板型分束器设置在两个集成的盘之间，其中多个微透镜和微小孔与其相同 并且其中入射光的轴线相对于微透镜的垂直入射轴线倾斜了一个有效的角度，从而消除了由板式分光器产生的光轴偏移，并且到相关微透镜的入射光为 引起聚焦到相应的微小开口，从而提高光的使用效率。

    Confocal optical scanner
    22.
    发明授权
    Confocal optical scanner 失效
    共焦光学扫描仪

    公开(公告)号：US5633751A

    公开(公告)日：1997-05-27

    申请号：US626014

    申请日：1996-03-22

    Applicant: Takeo Tanaami ,  Kenta Mikuriya

    Inventor： Takeo Tanaami ,  Kenta Mikuriya

    IPC: G02B3/00 ,  G02B3/08 ,  G02B21/00 ,  G02B21/06

    CPC classification number: G02B3/0056 ,  G02B21/0044 ,  G02B21/0064 ,  G02B3/08 ,  G02B3/0006

    Abstract: A confocal optical scanner which realizes optical scanning without nonuniformity of brightness at the inside and outside periperies of the pinhole disk by arraying the pinholes along spiral tracks at the same pitch; which allows adjustment of decentering to be readily performed by disposing pinholes so that stripes do not occur even when decentering is large; which allows more incident light to be collected at the pinholes through a plurality of collector means by disposing the pinholes at focal points of the collector means; which improves luminous utilization efficacy by reducing the illumination area of light by adopting the collector means to focus outside of the aperture pupil; which prevents decrease of confocal resolution due to pinhole diameter by causing the light reflected from the sample to not enter a collector disk; and which reduces stray light from the pinhole disk by covering non-collector portions of the collector disk with a shading film.

    Abstract translation: 一种共焦光学扫描仪，通过以相同的间距沿着螺旋轨道排列针孔，实现光学扫描，而不会在针孔盘的内侧和外侧的亮度不均匀; 这允许通过布置针孔来容易地进行偏心调节，使得即使在偏心较大时也不会发生条纹; 这允许通过将针孔设置在收集器装置的焦点处，通过多个收集器装置在针孔处收集更多的入射光; 通过采用收集器装置聚焦在孔径光瞳外部，通过减少光的照明面积来提高发光效率; 通过使得从样品反射的光不进入集电盘，防止由于针孔直径引起的共聚焦分辨率降低; 并且通过用遮光膜覆盖收集盘的非集电器部分来减少来自针孔盘的杂散光。

    METHOD FOR MEASURING FLUORESCENT LIGHT AMOUNT OR LIGHT ABSORPTION AMOUNT AND DEVICE FOR MEASURING THE SAME
    24.
    发明申请
    METHOD FOR MEASURING FLUORESCENT LIGHT AMOUNT OR LIGHT ABSORPTION AMOUNT AND DEVICE FOR MEASURING THE SAME 有权
    用于测量荧光体积或光吸收量的方法和用于测量其的装置

    公开(公告)号：US20110031410A1

    公开(公告)日：2011-02-10

    申请号：US12848596

    申请日：2010-08-02

    Applicant: Takeo TANAAMI ,  Hidetoshi AOKI ,  Yumiko SUGIYAMA ,  Souichirou SHIMODA ,  Muneki ARARAGI

    Inventor： Takeo TANAAMI ,  Hidetoshi AOKI ,  Yumiko SUGIYAMA ,  Souichirou SHIMODA ,  Muneki ARARAGI

    IPC: G01J1/58 ,  G01N21/00

    CPC classification number: G01N21/6452 ,  G01N21/6428

    Abstract: An amount of fluorescent light generated from the specimen is quantitatively measured as “a light-amount value per unit area traceable to the national standard” instead of in terms of a ratio (a ratio value) as in the past. A method for measuring a fluorescent light amount, whereby a specimen is irradiated with excitation light, and fluorescent light generated from the specimen is measured by a light-receiving element via a receiving optical system, said method comprising the steps of irradiating the specimen with excitation light having a light-amount value per specified unit area traceable to the national standard, and designated on the surface of the specimen beforehand, causing the light-receiving element to measure the fluorescent light generated from the specimen via the receiving optical system, and computing a fluorescent light-amount as measured by the light-receiving element via the receiving optical system on the basis of an excitation light-amount per the specified unit area, optical coefficients of the receiving optical system, and the acceptance coefficient of the light-receiving element, thereby working out a light amount value per the unit area traceable to the national standard.

    Abstract translation: 从样本产生的荧光量定量测量为“可追溯到国家标准的每单位面积的光量值”，而不是像过去的比率（比值）。 一种用于测量荧光量的方法，其中用激发光照射样本，并且通过接收光学系统由光接收元件测量从样本产生的荧光，所述方法包括以下步骤：用激发照射样本 具有可追溯到国家标准的每个指定单位面积的光量值的光，并且预先在样品表面上指定，使得光接收元件经由接收光学系统测量从样本产生的荧光，并计算 基于每个指定单位面积的激发光量，由受光元件经由接收光学系统测量的荧光量，接收光学系统的光学系数和光接收的接收系数 从而计算出可追溯到国家标准的单位面积的光量值。

    Chemical reaction cartridge
    26.
    发明授权
    Chemical reaction cartridge 有权
    化学反应筒

    公开(公告)号：US07794669B2

    公开(公告)日：2010-09-14

    申请号：US12014184

    申请日：2008-01-15

    Applicant: Katsumori Gyonouchi ,  Takeo Tanaami

    Inventor： Katsumori Gyonouchi ,  Takeo Tanaami

    IPC: B01J10/02 ,  B01L3/00 ,  G01N31/22 ,  A61M1/00

    CPC classification number: B01L3/502 ,  B01L2200/0689 ,  B01L2300/0887 ,  B01L2300/123 ,  B01L2400/0481 ,  B01L2400/0655

    Abstract: Disclosed is a chemical reaction cartridge including a substrate which is a rigid body and an elastic body, and a flow path and two or more chambers connected by the flow path are formed inside the cartridge, the cartridge is structured so as to move or block a fluid substance in the flow path or the chamber by partially sealing the flow path, the chamber or the both of the flow path and the chamber by applying external force to the elastic body from outside, and the substrate includes convex portions which protrude further than the elastic body at a surface of the substrate, on which the elastic body is formed.

    Abstract translation: 公开了一种化学反应盒，其包括刚性体和弹性体的基底，并且流体路径和通过流路连接的两个或更多个室形成在药筒内部，药筒被构造成移动或阻塞 流体物质通过从外部向弹性体施加外力而部分地密封流路，腔室或流路和腔室两者，并且衬底包括突出部分 弹性体在其上形成有弹性体的基板的表面。

    CHEMICAL REACTION APPARATUS
    28.
    发明申请
    CHEMICAL REACTION APPARATUS 审中-公开
    化学反应装置

    公开(公告)号：US20100150783A1

    公开(公告)日：2010-06-17

    申请号：US12713259

    申请日：2010-02-26

    Applicant: Muneki ARARAGI ,  Takeo TANAAMI ,  Nobuyuki KAKURYU ,  Masakatsu NOGUCHI

    Inventor： Muneki ARARAGI ,  Takeo TANAAMI ,  Nobuyuki KAKURYU ,  Masakatsu NOGUCHI

    IPC: B01J19/00 ,  G05B1/00

    CPC classification number: B01L3/50273 ,  B01L2300/0816 ,  B01L2300/0864 ,  B01L2300/0867 ,  B01L2400/0481 ,  B01L2400/0655

    Abstract: A chemical reaction apparatus in which a chemical reaction of solutions is carried out by transferring the solutions includes moving units to seal or move the solutions in a flow passage or a plurality of chambers of a container by applying an external force to an elastic body of the container by moving on a surface of the elastic body while the moving units contact with the surface of the elastic body, the moving units being movable independently from each other with respect to a cartridge including the container which is at least partially structured with the elastic body, the container including the plurality of chambers to contain the solutions and the flow passage to connect the plurality of chambers, and a detection unit to detect a state of solution pool in the flow passage or the chamber.

    Abstract translation: 通过转移溶液来进行溶液的化学反应的化学反应装置包括移动单元，以通过向外部的弹性体施加外力来将溶液密封或移动到容器的流路或多个室中 容器通过在弹性体的表面上移动而移动单元与弹性体的表面接触，移动单元可相对于包括至少部分地由弹性体构成的容器彼此独立地移动 所述容器包括用于容纳所述溶液的所述多个室和用于连接所述多个室的流路;以及检测单元，用于检测所述流路或所述室中的溶液池的状态。

    CHEMICAL REACTION CARTRIDGE
    29.
    发明申请
    CHEMICAL REACTION CARTRIDGE 审中-公开
    化学反应盒

    公开(公告)号：US20090263294A1

    公开(公告)日：2009-10-22

    申请号：US12426554

    申请日：2009-04-20

    Applicant: Hidetoshi AOKI ,  Takeyuki MOGI ,  Takeo TANAAMI

    Inventor： Hidetoshi AOKI ,  Takeyuki MOGI ,  Takeo TANAAMI

    IPC: B01J14/00

    CPC classification number: B01L3/50273 ,  B01L2200/141 ,  B01L2300/0636 ,  B01L2300/0816 ,  B01L2400/0481 ,  B01L2400/0655

    Abstract: Disclosed is a chemical reaction cartridge including an elastic body as a construction material and a flow path and two or more chambers connected by the flow path formed inside the cartridge, and the cartridge is structured so as to move or block a fluid material in the flow path or the chambers by partially sealing the flow path, the chambers or both the flow path and the chambers by applying external force to the elastic body from outside, as one of the chambers, the cartridge has a reaction chamber, the reaction chamber is a chamber in which a chemical reaction of a reaction liquid to be introduced in the reaction chamber is carried out, and a specific liquid to fill a space in the reaction chamber is filled in the reaction chamber before the reaction liquid is introduced in the reaction chamber.

    Abstract translation: 公开了一种化学反应盒，其包括作为构造材料的弹性体和流路以及通过形成在筒内部的流动路径连接的两个或更多个室，并且盒被构造成移动或阻挡流体中的流体材料 路径或室，通过从外部向弹性体施加外力，通过部分地密封流动路径，腔室或两者的流动路径和腔室，作为其中一个腔室，盒具有反应室，反应室为 其中进行反应室中引入的反应液体的化学反应的室，并且在将反应液体引入反应室之前，将填充反应室中的空间的特定液体填充在反应室中。

    CHEMICAL REACTION CARTRIDGE
    30.
    发明申请
    CHEMICAL REACTION CARTRIDGE 有权
    化学反应盒

    公开(公告)号：US20080187469A1

    公开(公告)日：2008-08-07

    申请号：US12014184

    申请日：2008-01-15

    Applicant: Katsumori GYONOUCHI ,  Takeo Tanaami

    Inventor： Katsumori GYONOUCHI ,  Takeo Tanaami

    IPC: B01J19/00

    CPC classification number: B01L3/502 ,  B01L2200/0689 ,  B01L2300/0887 ,  B01L2300/123 ,  B01L2400/0481 ,  B01L2400/0655

    Abstract: Disclosed is a chemical reaction cartridge including a substrate which is a rigid body and an elastic body, and a flow path and two or more chambers connected by the flow path are formed inside the cartridge, the cartridge is structured so as to move or block a fluid substance in the flow path or the chamber by partially sealing the flow path, the chamber or the both of the flow path and the chamber by applying external force to the elastic body from outside, and the substrate includes convex portions which protrude further than the elastic body at a surface of the substrate, on which the elastic body is formed.

    Abstract translation: 公开了一种化学反应盒，其包括刚性体和弹性体的基底，并且流体路径和通过流路连接的两个或更多个室形成在药筒内部，药筒被构造成移动或阻塞 流体物质通过从外部向弹性体施加外力而部分地密封流路，腔室或流路和腔室两者，并且衬底包括突出部分 弹性体在其上形成有弹性体的基板的表面。

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