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公开(公告)号：US20180251567A1
公开(公告)日：2018-09-06
申请号：US15983361
申请日：2018-05-18
Applicant: Genentech, Inc.
Inventor： Mark Dennis , Bonnee Rubinfeld , Paul Polakis
IPC: C07K16/30 , G01N33/574 , A61K47/68 , A61K31/537 , A61K45/06 , C07K16/18 , C07K16/28 , A61K39/00
CPC classification number: C07K16/30 , A61K31/537 , A61K45/06 , A61K47/6803 , A61K47/6809 , A61K47/6813 , A61K47/6817 , A61K47/6849 , A61K47/6851 , A61K47/6857 , A61K47/6869 , A61K2039/505 , C07K16/18 , C07K16/28 , C07K16/3023 , C07K16/3069 , C07K2317/14 , C07K2317/24 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/73 , C07K2317/76 , C07K2317/77 , C07K2317/92 , G01N33/57423 , G01N33/57449 , G01N33/57492
Abstract: The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
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公开(公告)号：US09994643B2
公开(公告)日：2018-06-12
申请号：US15341261
申请日：2016-11-02
Applicant: Genentech, Inc.
Inventor： Mark Dennis , Bonnee Rubinfeld , Paul Polakis
IPC: C07K16/30 , A61K47/48 , C07K16/28 , G01N33/574 , A61K45/06 , C07K16/18 , A61K31/537 , A61K39/00
CPC classification number: C07K16/30 , A61K31/537 , A61K45/06 , A61K47/6803 , A61K47/6809 , A61K47/6813 , A61K47/6817 , A61K47/6849 , A61K47/6851 , A61K47/6857 , A61K47/6869 , A61K2039/505 , C07K16/18 , C07K16/28 , C07K16/3023 , C07K16/3069 , C07K2317/14 , C07K2317/24 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/73 , C07K2317/76 , C07K2317/77 , C07K2317/92 , G01N33/57423 , G01N33/57449 , G01N33/57492
Abstract: The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
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公开(公告)号：US09632091B2
公开(公告)日：2017-04-25
申请号：US14919388
申请日：2015-10-21
Applicant: Genentech, Inc.
Inventor： Siminder Atwal , Jo-Anne Hongo , Mark Lackner , Elizabeth Punnoose , Bonnee Rubinfeld , Rajesh Vij
IPC: G01N33/53 , G01N33/574 , C07K16/30 , C12N5/09
CPC classification number: G01N33/57434 , C07K16/3069 , C12N5/0693 , C12Y116/01 , C12Y301/03048 , G01N33/57492 , G01N2333/4742 , G01N2333/70596 , G01N2333/90287 , G01N2333/916 , G01N2800/52
Abstract: The invention provides methods for diagnosing prostate cancer. The invention also provides novel anti-STEAP-1 antibodies and uses thereof.
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公开(公告)号：US20170073424A1
公开(公告)日：2017-03-16
申请号：US15341261
申请日：2016-11-02
Applicant: Genentech, Inc.
Inventor： Mark Dennis , Bonnee Rubinfeld , Paul Polakis
IPC: C07K16/30 , A61K47/48 , A61K31/537 , G01N33/574
CPC classification number: C07K16/30 , A61K31/537 , A61K45/06 , A61K47/6803 , A61K47/6809 , A61K47/6813 , A61K47/6817 , A61K47/6849 , A61K47/6851 , A61K47/6857 , A61K47/6869 , A61K2039/505 , C07K16/18 , C07K16/28 , C07K16/3023 , C07K16/3069 , C07K2317/14 , C07K2317/24 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/73 , C07K2317/76 , C07K2317/77 , C07K2317/92 , G01N33/57423 , G01N33/57449 , G01N33/57492
Abstract: The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
Abstract translation: 本发明涉及用于哺乳动物肿瘤诊断和治疗的物质组合物，以及使用这些物质组合物的方法。
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公开(公告)号：US09556267B2
公开(公告)日：2017-01-31
申请号：US14466794
申请日：2014-08-22
Applicant: Genentech, Inc.
Inventor： Eric Bourhis , Rick Carano , Andrea Cochran , Mike Costa , Venita DeAlmeida , James Ernst , Yan Gong , Rami Hannoush , Paul Polakis , Bonnee Rubinfeld , Mark Solloway , Yan Wu
IPC: A61K39/395 , C07K16/28 , A61K39/00
CPC classification number: C07K16/28 , A61K39/3955 , A61K2039/505 , A61K2039/507 , C07K16/2863 , C07K2317/21 , C07K2317/31 , C07K2317/34 , C07K2317/526 , C07K2317/55 , C07K2317/75 , C07K2317/76 , C07K2317/92 , C07K2319/00
Abstract: The invention provides anti-LRP6 antibodies and methods of using the same. A particular aspect of the invention provides for bispecific anti-LRP6 antibodies that inhibit signaling by multiple Wnt isoforms.
Abstract translation: 本发明提供抗LRP6抗体及其使用方法。 本发明的一个特定方面提供了抑制多种Wnt同种型的信号通路的双特异性抗LRP6抗体。
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Patent Agency Ranking
公开(公告)号：US09029511B2
公开(公告)日：2015-05-12
申请号：US13963269
申请日：2013-08-09
Applicant: Genentech, Inc.
Inventor： Mark Dennis , Bonnee Rubinfeld , Paul Polakis
CPC classification number: C07K16/30 , A61K31/537 , A61K45/06 , A61K47/6803 , A61K47/6809 , A61K47/6813 , A61K47/6817 , A61K47/6849 , A61K47/6851 , A61K47/6857 , A61K47/6869 , A61K2039/505 , C07K16/18 , C07K16/28 , C07K16/3023 , C07K16/3069 , C07K2317/14 , C07K2317/24 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/73 , C07K2317/76 , C07K2317/77 , C07K2317/92 , G01N33/57423 , G01N33/57449 , G01N33/57492
Abstract: The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
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17.发明申请公开(公告)号：US20150056132A1
公开(公告)日：2015-02-26
申请号：US14287826
申请日：2014-05-27
Applicant: Genentech, Inc.
Inventor： Mark DENNIS , Jan Marik , Paul Polakis , Bonnee Rubinfeld , Simon Williams
CPC classification number: C07K16/40 , A61K47/6811 , A61K47/6871 , A61K51/1072 , A61K51/1075 , A61K51/1093 , A61K51/1096 , A61K2039/505 , C07B59/008 , C07B2200/05 , C07K16/3069 , C07K2317/24 , C07K2317/565 , C07K2317/92 , G01N33/534 , G01N33/57492 , G01N33/60 , G01N33/6893
Abstract: Anti-STEAP-1 antibodies and immunoconjugates thereof are provided. Methods of using anti-STEAP-1 antibodies and immunoconjugates thereof are provided. Methods of detecting or determining the presence of STEAP-1 proteins are provided.
Abstract translation: 提供抗STEAP-1抗体及其免疫偶联物。 提供了使用抗STEAP-1抗体及其免疫偶联物的方法。 提供检测或确定STEAP-1蛋白存在的方法。
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公开(公告)号：US20140079721A1
公开(公告)日：2014-03-20
申请号：US13963269
申请日：2013-08-09
Applicant: Genentech, Inc.
Inventor： Mark Dennis , Bonnee Rubinfeld , Paul Polakis
CPC classification number: C07K16/30 , A61K31/537 , A61K45/06 , A61K47/6803 , A61K47/6809 , A61K47/6813 , A61K47/6817 , A61K47/6849 , A61K47/6851 , A61K47/6857 , A61K47/6869 , A61K2039/505 , C07K16/18 , C07K16/28 , C07K16/3023 , C07K16/3069 , C07K2317/14 , C07K2317/24 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/73 , C07K2317/76 , C07K2317/77 , C07K2317/92 , G01N33/57423 , G01N33/57449 , G01N33/57492
Abstract: The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
Abstract translation: 本发明涉及用于哺乳动物肿瘤诊断和治疗的物质组合物，以及使用这些物质组合物的方法。
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公开(公告)号：US20130316402A1
公开(公告)日：2013-11-28
申请号：US13766150
申请日：2013-02-13
Applicant: GENENTECH, INC.
Inventor： Mark S. Dennis , Bonnee Rubinfeld , Paul Polakis , Aya Jakobovits
IPC: C07K16/30
CPC classification number: G01N33/57434 , A61K38/05 , A61K39/39558 , A61K45/06 , A61K47/6851 , A61K47/6869 , A61K47/6871 , A61K49/0002 , A61K49/0058 , A61K51/1045 , A61K51/1072 , A61K2039/505 , C07K16/30 , C07K16/3069 , C07K16/40 , C07K17/00 , C07K2317/24 , C07K2317/31 , C07K2317/515 , C07K2317/54 , C07K2317/55 , C07K2317/565 , C07K2317/567 , C07K2317/622 , C07K2317/92
Abstract: Anti-STEAP-1 antibodies and immunoconjugates thereof are provided. Methods of using anti-STEAP-1 antibodies and immunoconjugates thereof are provided.
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公开(公告)号：US20130157289A1
公开(公告)日：2013-06-20
申请号：US13692888
申请日：2012-12-03
Applicant: Genentech, Inc.
Inventor： Mark Dennis , Jan Marik , Paul Polakis , Bonnee Rubinfeld , Simon Williams
CPC classification number: C07K16/40 , A61K47/6811 , A61K47/6871 , A61K51/1072 , A61K51/1075 , A61K51/1093 , A61K51/1096 , A61K2039/505 , C07B59/008 , C07B2200/05 , C07K16/3069 , C07K2317/24 , C07K2317/565 , C07K2317/92 , G01N33/534 , G01N33/57492 , G01N33/60 , G01N33/6893
Abstract: Anti-STEAP-1 antibodies and immunoconjugates thereof are provided. Methods of using anti-STEAP-1 antibodies and immunoconjugates thereof are provided. Methods of detecting or determining the presence of STEAP-1 proteins are provided.
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