METHOD FOR MAKING COATED SILICONE HYDROGEL CONTACT LENSES

    公开(公告)号:US20200172756A1

    公开(公告)日:2020-06-04

    申请号:US16426506

    申请日:2019-05-30

    Applicant: Alcon Inc.

    Abstract: The invention is generally related to a method for producing coated silicone hydrogel contact lenses each of which has a hydrogel coating thereon and a relative high resistance to uptakes of polycationic antimicrobials as characterized by having a polyquaternium-1-uptake of less than 0.40 micrograms/lens. The hydrogel coating is formed by covalently attached a hydrophilic polymeric material onto a base coating of a polyanionic polymer on a SiHy contact lens. In this method, lower polyquaternium-1-uptake is achieved by using a rinse solution with a higher pH and/or a higher ionic strength (higher salt concentration) for rinsing a treated silicone hydrogel contact lens with a base coating of polyanionic polymer.

    METHOD FOR APPLYING A COATING ONTO A NON-SILICONE HYDROGEL LENS

    公开(公告)号:US20220372391A1

    公开(公告)日:2022-11-24

    申请号:US17659972

    申请日:2022-04-20

    Applicant: Alcon Inc.

    Abstract: The present invention generally relates to a method for applying a coating of hydrophilic polymers onto polyvinylalcohol-based hydrogel contact lenses to improve lubricity. In particular, the present invention is directed to a method for forming a coating on a contact lens, preferably a polyvinylalcohol-based hydrogel contact lens, directly in the primary package and maintaining the coated contact lens within said primary package until insertion of the coated contact lens in the eye of the contact lens user. The resultant polyvinylalcohol-based hydrogel contact lens has a coating with improved lubricity and good durability and also can be used directly from the lens package by a patient without washing and/or rinsing.

    Method for producing coated silicone hydrogel contact lenses

    公开(公告)号:US11099300B2

    公开(公告)日:2021-08-24

    申请号:US16426451

    申请日:2019-05-30

    Applicant: Alcon Inc.

    Abstract: The invention is generally related to a method for producing, in a consistent manner, SiHy contact lenses each having an intact durable coating thereon, wherein the coating is a hydrogel coating formed by covalently attached a hydrophilic polymeric material onto a base coating of a polyanionic polymer on a SiHy contact lens. In this method, the base coating is formed by having two solution coating steps separated by at least one rinsing step with a buffered saline or pH controlled solution. The durability of the hydrogel coatings on resultant silicone hydrogel contact lenses can be improved significantly and will not vary with the optical power (i.e., the center thickness) of the SiHy contact lens under coating.

    METHOD FOR PRODUCING COATED CONTACT LENSES
    16.
    发明申请

    公开(公告)号:US20200324314A1

    公开(公告)日:2020-10-15

    申请号:US16843989

    申请日:2020-04-09

    Applicant: Alcon Inc.

    Abstract: The invention is generally related to a method for producing, in a consistent manner, contact lenses each having an intact durable coating thereon, wherein the coating is a hydrogel coating formed by covalently attached a hydrophilic polymeric material having azetidinium groups onto a base coating of a polyanionic polymer on a contact lens at a relatively low temperature (e.g., from about 40° C. to about 60° C.). The coating temperature for forming a durable hydrogel coating on top of the base coating of a contact lens can be significantly lowered by raising, in situ, the pH (to about 9.5 or higher) of a reactive coating solution which contains the hydrophilic polymeric material having azetidinium groups.

    METHOD FOR COATED SILICONE HYDROGEL CONTACT LENSES

    公开(公告)号:US20200174160A1

    公开(公告)日:2020-06-04

    申请号:US16426451

    申请日:2019-05-30

    Applicant: Alcon Inc.

    Abstract: The invention is generally related to a method for producing, in a consistent manner, SiHy contact lenses each having an intact durable coating thereon, wherein the coating is a hydrogel coating formed by covalently attached a hydrophilic polymeric material onto a base coating of a polyanionic polymer on a SiHy contact lens. In this method, the base coating is formed by having two solution coating steps separated by at least one rinsing step with a buffered saline or pH controlled solution. The durability of the hydrogel coatings on resultant silicone hydrogel contact lenses can be improved significantly and will not vary with the optical power (i.e., the center thickness) of the SiHy contact lens under coating.

    CONTACT LENSES WITH SURFACES HAVING DIFFERENT SOFTNESS

    公开(公告)号:US20240377654A1

    公开(公告)日:2024-11-14

    申请号:US18777289

    申请日:2024-07-18

    Applicant: Alcon Inc.

    Abstract: The invention is related to a contact lens, especially a SiHy contact lens, which comprises a lens bulk material covered with an outer surface hydrogel layer thereon and has a posterior surface and an opposite anterior surface. The outer surface hydrogel layer consists of an anterior outer hydrogel layer and a posterior outer hydrogel layer. A contact lens of the invention is characterized by having a difference in surface softness between its poterior (BC) and anterior (FC) surfaces.

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