公开(公告)号：US11459479B2

公开(公告)日：2022-10-04

申请号：US16426506

申请日：2019-05-30

Applicant: Alcon Inc.

Inventor： Yongxing Qiu ,  Chung-Yuan Chiang ,  Newton T. Samuel ,  Richard Govan ,  Ciara Dauenhauer

IPC: C09D133/02 ,  B29D11/00 ,  B29K683/00 ,  G02C7/04

Abstract: The invention is generally related to a method for producing coated silicone hydrogel contact lenses each of which has a hydrogel coating thereon and a relative high resistance to uptakes of polycationic antimicrobials as characterized by having a polyquaternium-1-uptake of less than 0.40 micrograms/lens. The hydrogel coating is formed by covalently attached a hydrophilic polymeric material onto a base coating of a polyanionic polymer on a SiHy contact lens. In this method, lower polyquaternium-1-uptake is achieved by using a rinse solution with a higher pH and/or a higher ionic strength (higher salt concentration) for rinsing a treated silicone hydrogel contact lens with a base coating of polyanionic polymer.

公开(公告)号：US20200172756A1

公开(公告)日：2020-06-04

申请号：US16426506

申请日：2019-05-30

Applicant: Alcon Inc.

Inventor： Yongxing Qiu ,  Chung-Yuan Chiang ,  Newton T. Samuel ,  Richard Govan ,  Ciara Dauenhauer

IPC: C09D133/02 ,  B29D11/00

Abstract: The invention is generally related to a method for producing coated silicone hydrogel contact lenses each of which has a hydrogel coating thereon and a relative high resistance to uptakes of polycationic antimicrobials as characterized by having a polyquaternium-1-uptake of less than 0.40 micrograms/lens. The hydrogel coating is formed by covalently attached a hydrophilic polymeric material onto a base coating of a polyanionic polymer on a SiHy contact lens. In this method, lower polyquaternium-1-uptake is achieved by using a rinse solution with a higher pH and/or a higher ionic strength (higher salt concentration) for rinsing a treated silicone hydrogel contact lens with a base coating of polyanionic polymer.