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公开(公告)号：US20250017825A1
公开(公告)日：2025-01-16
申请号：US18577029
申请日：2022-06-23
Applicant: AMGEN INC.
Inventor： Todd Neslund , Stephen Karl Shutt , Eunah Choi , Alberto David Herrera , Jordan Ray Fine , Thomas Clark Pearson
Abstract: A system for dispensing, inspecting, and/or processing drug includes a tray adapted to be operably coupled with a workstation, a handle member operably coupled with the tray, and a funnel region operably coupled with the tray. The tray has a body defining a recessed region and a sidewall positioned adjacent to the recessed region. The handle member is positioned at or near a first corner of the tray. The funnel region is positioned at or near a second corner of the tray. The first corner is opposite the second corner.
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公开(公告)号：US20240344920A1
公开(公告)日：2024-10-17
申请号：US18685086
申请日：2022-08-22
Applicant: AMGEN INC.
Inventor： Al Patrick Goodwin , Joseph Peter Bermacki , Thomas Clark Pearson , Graham F. Milne , Jonathan Parsons , Corey Bishop , Barry Donohoe , Osvaldo Perez-Varela
CPC classification number: G01M3/38 , G01B11/2522 , G01N21/909 , G01N2201/0612
Abstract: An apparatus, system, or method for vial seal inspection may be based on three-dimensional data that is representative of at least a portion of a vial seal. More particularly, apparatuses, systems, and methods for vial seal inspection may include at least one laser triangulation sensor.
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公开(公告)号：US20240314190A1
公开(公告)日：2024-09-19
申请号：US18577109
申请日：2022-07-20
Applicant: AMGEN INC.
Inventor： Tyler Bellenfant , Jeremy S. Conner , Sarah Whetstone , Thomas Clark Pearson
IPC: H04L65/80 , H04N21/236 , H04N21/472 , H04N23/62 , H04N23/661
CPC classification number: H04L65/80 , H04N21/236 , H04N21/472 , H04N23/62 , H04N23/661
Abstract: A telepresence system may include at least one telepresence device including a digital camera having camera control inputs and a video feed output. The system may also include at least one remote device having a web browser. The camera control inputs may be communicated from the remote device to the at least one telepresence device via an embedded webserver. The video feed output may be communicated to the remote device via a video server configured to transmit real-time video data from the digital camera, over a secure socket connection, to the remote device.
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公开(公告)号：US20230139131A1
公开(公告)日：2023-05-04
申请号：US18089109
申请日：2022-12-27
Applicant: AMGEN INC.
Inventor： Thomas Clark Pearson , Graham F. Milne , Dmitry Fradkin , Erwin Freund
Abstract: In a method for imaging a container holding a sample, the container is illuminated with a laser sheet of a first color, and one or more images of the container are capturing by a first imager configured to filter out colors other than the first color. Simultaneously with illuminating the container with the laser sheet of the first color, the container is illuminated with light of a second color different than the first color, wherein the light of the second color illuminates at least a majority of an entire volume of the container. One or more additional imagers of the container are captured by a second imager configured to filter out colors other than the second color. The one or more images and the one or more additional images are analyzed to detect particles within, and/or on an exterior surface of, the container.
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公开(公告)号：US10539773B2
公开(公告)日：2020-01-21
申请号：US16113489
申请日：2018-08-27
Applicant: AMGEN INC.
Inventor： Dmitry Fradkin , Graham F. Milne , Thomas Clark Pearson
Abstract: A system is described to facilitate the characterization of particles within a fluid contained in a vessel using an illumination system that directs source light through each vessel. One or more optical elements may be implemented to refract the source light and to illuminate the entire volume of the vessel. As the refracted source light passes through the vessel and interacts with particles suspended in the fluid, scattered light is produced and directed to an imager, while the refracted source light is diverted away from the imager to prevent the source light from drowning out the scattered light. The system can therefore advantageously utilize an imager with a large depth of field to accurately image the entire volume of fluid at the same time, facilitating the determination of the number and size of particles suspended in the fluid.
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Patent Agency Ranking
公开(公告)号：US20250130176A1
公开(公告)日：2025-04-24
申请号：US18835139
申请日：2023-02-07
Applicant: AMGEN INC.
Inventor： Thomas Clark Pearson , Graham F. Milne
IPC: G01N21/88 , G01N21/958
Abstract: An automated visual inspection (AVI) system may include at least one profile view imager having an optical axis that passes through an inspection object, a proximal polarizing film axially aligned with the optical axis, a liquid crystal device axially aligned with the optical axis, a distal polarizing film axially aligned with the optical axis, and at least one light source oriented to emit illumination toward the distal polarizing film. Alternatively, or additionally, an AVI system may include a profile view imager having an optical axis that enters a container through a side wall of the container, and a ring light that is coaxially aligned with a central axis of the container, below the container, and oriented to emit light toward a bottom of the container. The AVI system may also include a bottom imager coaxially aligned with the central axis and oriented to view the bottom of the container.
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公开(公告)号：US11900540B2
公开(公告)日：2024-02-13
申请号：US17616548
申请日：2020-06-02
Applicant: AMGEN INC.
Inventor： Graham F. Milne , Dmitry Fradkin , Thomas Clark Pearson
CPC classification number: G06T17/20 , G01N15/0227 , G01N15/06 , G06T7/20 , G06T15/06 , G06V10/763 , H04N5/06 , G01N2015/0693 , G06T2200/08 , G06T2207/30242
Abstract: A method for 3D imaging of a sample, in a vessel having a longitudinal axis orthogonal to a horizontal plane, includes capturing, by at least three cameras located at different positions around the vessel, respective 2D images of the sample. Each image comprises pixels having associated pixel values. The optical axis of a first camera is inclined or declined at a first angle relative to the horizontal plane, with the first angle being greater than or equal to zero degrees. The optical axis of a second camera is inclined or declined at a second, larger angle relative to the horizontal plane. The method also includes generating a 3D image of the sample based on the pixel values associated with the 2D image pixels, and one or more look-up tables that collectively indicate, for pixels in each image, expected paths for light traversing the vessel and the sample.
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公开(公告)号：US11592403B2
公开(公告)日：2023-02-28
申请号：US17414544
申请日：2019-12-16
Applicant: AMGEN INC.
Inventor： Thomas Clark Pearson , Graham F. Milne , Dmitry Fradkin , Erwin Freund
Abstract: In a method for imaging a container holding a sample, the container is illuminated with a laser sheet that impinges upon the container in a first direction corresponding to a first axis. A plane of the laser sheet is defined by the first axis and a second axis orthogonal to the first axis. The method also includes capturing, by a camera having an imaging axis that is substantially orthogonal to at least the first axis, an image of the container. The method further includes analyzing, by one or more processors, the image of the container to detect particles within, and/or on an exterior surface of, the container.
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公开(公告)号：US20220230394A1
公开(公告)日：2022-07-21
申请号：US17616548
申请日：2020-06-02
Applicant: AMGEN INC.
Inventor： Graham F. Milne , Dmitry Fradkin , Thomas Clark Pearson
Abstract: A method for 3D imaging of a sample, in a vessel having a longitudinal axis orthogonal to a horizontal plane, includes capturing, by at least three cameras located at different positions around the vessel, respective 2D images of the sample. Each image comprises pixels having associated pixel values. The optical axis of a first camera is inclined or declined at a first angle relative to the horizontal plane, with the first angle being greater than or equal to zero degrees. The optical axis of a second camera is inclined or declined at a second, larger angle relative to the horizontal plane. The method also includes generating a 3D image of the sample based on the pixel values associated with the 2D image pixels, and one or more look-up tables that collectively indicate, for pixels in each image, expected paths for light traversing the vessel and the sample.
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公开(公告)号：US20200338271A1
公开(公告)日：2020-10-29
申请号：US16761149
申请日：2018-11-06
Applicant: AMGEN INC.
Inventor： Justin Harris , Matthew Wayne Janke , Wael Mismar , Jerome Olivas , Thomas Clark Pearson , Sudeshna Dutta Ray , Ryan M. Agard , Alexis Dechelette , Michael Gammelager , Mads Hansen , Valerio Mazzon , Owen Ryan , Clive Smith
Abstract: Fill-finish assemblies facilitating the manufacture of a drug delivery device are disclosed. The fill-finish assembly may include a container, an insertion mechanism, a fluid pathway connection assembly disposed between the container and the insertion mechanism, and a carrier. The insertion mechanism may include a delivery member and an insertion mechanism housing. The insertion mechanism may be configured to move the delivery member from a retracted position inside the insertion mechanism housing to a deployed position outside the insertion mechanism housing. The fluid pathway connection assembly may be selectively activatable to establish fluid communication between the container and the delivery member. The carrier may have a hollow interior containing at least a portion of each of the container, the insertion mechanism, and the fluid pathway connection assembly. The carrier may be configured to hold the container, the insertion mechanism, and the fluid pathway connection assembly in alignment with each other.
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