公开(公告)号：US07236434B2

公开(公告)日：2007-06-26

申请号：US10975605

申请日：2004-10-28

Applicant: Masahiko Tsukuda ,  Shinya Abe ,  Morio Tomiyama ,  Shuji Sato ,  Eiichi Ito

Inventor： Masahiko Tsukuda ,  Shinya Abe ,  Morio Tomiyama ,  Shuji Sato ,  Eiichi Ito

IPC: G11B7/26 ,  G11B7/135

CPC classification number: G11B7/261 ,  G11B7/128 ,  G11B7/1378

Abstract: Apparatus and method for exposing an optical disk master having a laser source, a deflector for deflecting a recording laser beam based on the laser beam of the laser source and an objective lens for focusing the recording laser beam on an optical disk master, including a liquid crystal plate provided between the laser source and the deflector, a parallel flat plate provided between the deflector and the objective lens, a photodetector that detects reflected light from the parallel flat plate, and an adjusting device for adjusting a voltage applied to the liquid crystal plate based on information on wavefront fluctuation of the recording laser beam detected by the photodetector.

Abstract translation: 用于曝光具有激光源的光盘主机的装置和方法，用于基于激光源的激光束偏转记录激光束的偏转器和用于将记录激光束聚焦在包括液体的光盘主机的物镜 设置在激光源和偏转器之间的晶体板，设置在偏转器和物镜之间的平行平板，检测来自平行平板的反射光的光电检测器，以及用于调节施加到液晶板的电压的调节装置 基于由光电检测器检测的记录激光束的波前波动的信息。

公开(公告)号：US20070092821A1

公开(公告)日：2007-04-26

申请号：US11401968

申请日：2006-04-12

Applicant: Shuji Sato ,  Shigeru Hayashi ,  Katsumi Daimon

Inventor： Shuji Sato ,  Shigeru Hayashi ,  Katsumi Daimon

IPC: G03G9/08

CPC classification number: G03G9/08755 ,  G03G9/0806 ,  G03G9/0819 ,  G03G9/0827 ,  G03G9/08795 ,  G03G9/08797

Abstract: The present invention relates to a toner for electrostatic image development, comprising a crystalline ester compound synthesized by polymerizing a carboxylic acid component with an alcohol component, a non-crystalline resin, a colorant and a releasing agent, wherein the weight-average molecular weight of the crystalline ester compound is 5000 or less, and the number of carbon atoms in at least one component selected from the carboxylic acid component and the alcohol component is 10 or more.

Abstract translation: 本发明涉及一种用于静电图像显影的调色剂，其包含通过使羧酸组分与醇组分，非结晶树脂，着色剂和脱模剂聚合而合成的结晶酯化合物，其中重均分子量 结晶酯化合物为5000以下，选自羧酸成分和醇成分中的至少一种成分中的碳原子数为10以上。

公开(公告)号：US07202040B2

公开(公告)日：2007-04-10

申请号：US10499172

申请日：2002-12-13

Applicant: Masaaki Mori ,  Tomoko Chikatsu ,  Shuji Sato ,  Toshimi Nagi ,  Tsukasa Sugo

Inventor： Masaaki Mori ,  Tomoko Chikatsu ,  Shuji Sato ,  Toshimi Nagi ,  Tsukasa Sugo

IPC: G01N33/53 ,  G01N33/00 ,  C12Q1/68 ,  C12N15/00 ,  A61K38/02 ,  A61K38/16

CPC classification number: C07K14/705 ,  A61K31/00 ,  G01N2500/02 ,  Y10S435/975

Abstract: The present invention relates to a screening method/screening kit for screening a compound or its salt that changes the binding properties of (a) a protein containing the same or substantially the same amino acid sequence as the amino acid sequence represented by SEQ ID NO: 1 or SEQ ID NO: 19, its partial peptides, or salts thereof, and (b) a ligand capable of binding specifically to the protein; compounds obtained by the screening or salts thereof; pharmaceuticals comprising the compounds or salts thereof; a protein containing the same or substantially the same amino acid sequence as the amino acid sequence represented by SEQ ID NO: 19; etc. The compounds obtained by the screening of the present invention are useful as agents for the prevention/treatment of, for example, neurodegenerative diseases, immunological diseases, edema, acid indigestion, etc.

Abstract translation: 本发明涉及一种用于筛选化合物或其盐的筛选方法/筛选试剂盒，其改变（a）含有与SEQ ID NO：1所示的氨基酸序列相同或基本相同的氨基酸序列的蛋白质的结合特性。 1或SEQ ID NO：19，其部分肽或其盐，和（b）能够特异性结合蛋白质的配体; 通过筛选获得的化合物或其盐; 包含其化合物或其盐的药物; 含有与SEQ ID NO：19所示的氨基酸序列相同或基本相同的氨基酸序列的蛋白质; 通过本发明的筛选获得的化合物可用作预防/治疗例如神经变性疾病，免疫疾病，水肿，酸消化不良等的试剂。

公开(公告)号：US20060110393A1

公开(公告)日：2006-05-25

申请号：US10540394

申请日：2003-12-25

Applicant: Eiji Sunahara ,  Takafumi Ishi ,  Koji Yamamoto ,  Shuji Sato

Inventor： Eiji Sunahara ,  Takafumi Ishi ,  Koji Yamamoto ,  Shuji Sato

IPC: A61K48/00 ,  C12Q1/68 ,  G01N33/574 ,  A61K39/395 ,  C07K14/82 ,  C07K16/30

CPC classification number: C07K14/47

Abstract: Compounds that inhibit the expression of a protein comprising the same or substantially the same amino acid sequence as the amino acid sequence represented by SEQ ID NO: 1, SEQ ID NO: 4, SEQ ID NO: 7 or SEQ ID NO: 10 or the expression of a gene for the protein, the antisense polynucleotide comprising the entire or part of a base sequence complementary or substantially complementary to DNA encoding the protein or its partial peptide, the antibody to the protein or its partial peptide, etc. are useful as prophylactic/therapeutic agents for cancer, etc., apoptosis promoters, etc.

Abstract translation: 抑制包含与SEQ ID NO：1，SEQ ID NO：4，SEQ ID NO：7或SEQ ID NO：10所示的氨基酸序列相同或基本相同的氨基酸序列的蛋白质的表达的化合物或 表达蛋白质的基因，包含与编码蛋白质或其部分肽的DNA互补或基本上互补的碱基序列的全部或部分的反义多核苷酸，对蛋白质或其部分肽的抗体等可用作预防性 癌症治疗剂等，细胞凋亡启动子等

公开(公告)号：US06998186B2

公开(公告)日：2006-02-14

申请号：US10445348

申请日：2003-05-22

Applicant: Shuji Sato ,  Masahiro Ise ,  Koji Okazaki

Inventor： Shuji Sato ,  Masahiro Ise ,  Koji Okazaki

IPC: H01M8/04 ,  H01M2/00 ,  H01M2/14

CPC classification number: H01M8/04074 ,  H01M8/0263 ,  H01M8/0267 ,  H01M8/0271 ,  H01M8/04007 ,  H01M8/04014 ,  H01M8/04029 ,  H01M8/241 ,  H01M8/2457 ,  H01M8/2483 ,  H01M2250/20 ,  Y02T90/32

Abstract: A fuel cell stack includes power generation cells, terminal plates, first cooling cells, and second cooling cells. The terminal plates are electrically connected to the power generation cells. The first cooling cells are interposed between the terminal plates, and a cooling liquid is supplied to the first cooling cells for cooling the power generation cells. The second cooling cells are interposed between the terminal plates. A predetermined number of power generation cells are interposed between the first cooling cell and the second cooling cell. A cooling air is supplied to the second cooling cell for cooing the power generation cells.

Abstract translation: 燃料电池堆包括发电单元，端子板，第一冷却单元和第二冷却单元。 端子板电连接到发电单元。 将第一冷却单元插入端子板之间，向第一冷却单元供给冷却液，以冷却发电单元。 第二冷却单元插在端子板之间。 预定数量的发电单元被插入在第一冷却单元和第二冷却单元之间。 向第二冷却单元供应冷却空气以冷却发电单元。

公开(公告)号：US06978172B2

公开(公告)日：2005-12-20

申请号：US10335641

申请日：2002-12-30

Applicant: Kenji Mori ,  Iwao Nozawa ,  Shuji Sato

Inventor： Kenji Mori ,  Iwao Nozawa ,  Shuji Sato

IPC: A61N1/30 ,  A61N1/32

CPC classification number: A61N1/0424 ,  A61N1/042 ,  A61N1/044 ,  A61N1/0444 ,  A61N1/327

Abstract: Electroporation electrodes are laminated to a permeable membrane to form an electrode membrane. Such an electrode membrane is useful for a continuous controlled delivery of a therapeutic agent through the skin or mucosa, when placed in direct contact with the skin or mucosa and by application of electric field pulses at specified intervals. An electrode membrane can be assembled such that it incorporates an iontophoretic electrode in the same device. This device can be jointly utilized for electroporation and iontophoretic drug delivery through the skin and mucosal membrane.

Abstract translation: 将电穿孔电极层压到可渗透膜上以形成电极膜。 当与皮肤或粘膜直接接触并且以规定的间隔施加电场脉冲时，这种电极膜可用于连续控制递送治疗剂通过皮肤或粘膜。 可以组装电极膜，使得其在同一装置中并入离子电渗电极。 该装置可以共同用于通过皮肤和粘膜的电穿孔和离子电渗药物递送。

公开(公告)号：US20050266286A1

公开(公告)日：2005-12-01

申请号：US10445348

申请日：2003-05-22

Applicant: Shuji Sato ,  Masahiro Ise ,  Koji Okazaki

Inventor： Shuji Sato ,  Masahiro Ise ,  Koji Okazaki

IPC: H01M8/00 ,  H01M8/02 ,  H01M8/04 ,  H01M8/10 ,  H01M8/24

CPC classification number: H01M8/04074 ,  H01M8/0263 ,  H01M8/0267 ,  H01M8/0271 ,  H01M8/04007 ,  H01M8/04014 ,  H01M8/04029 ,  H01M8/241 ,  H01M8/2457 ,  H01M8/2483 ,  H01M2250/20 ,  Y02T90/32

Abstract: A fuel cell stack includes power generation cells, terminal plates, first cooling cells, and second cooling cells. The terminal plates are electrically connected to the power generation cells. The first cooling cells are interposed between the terminal plates, and a cooling liquid is supplied to the first cooling cells for cooling the power generation cells. The second cooling cells are interposed between the terminal plates. A predetermined number of power generation cells are interposed between the first cooling cell and the second cooling cell. A cooling air is supplied to the second cooling cell for cooing the power generation cells.

Abstract translation: 燃料电池堆包括发电单元，端子板，第一冷却单元和第二冷却单元。 端子板电连接到发电单元。 将第一冷却单元插入端子板之间，向第一冷却单元供给冷却液，以冷却发电单元。 第二冷却单元插在端子板之间。 预定数量的发电单元被插入在第一冷却单元和第二冷却单元之间。 向第二冷却单元供应冷却空气以冷却发电单元。

公开(公告)号：US20050177092A1

公开(公告)日：2005-08-11

申请号：US10512442

申请日：2002-04-25

Applicant: Hirotoshi Adachi ,  Naruhito Higo ,  Shuji Sato ,  Aarti Naik ,  Yogeshvar Kalia ,  Richard Guy

Inventor： Hirotoshi Adachi ,  Naruhito Higo ,  Shuji Sato ,  Aarti Naik ,  Yogeshvar Kalia ,  Richard Guy

IPC: A61N1/30

CPC classification number: A61N1/30

Abstract: A device and assembly for administering antimicrobial for killing resident microorganisms on human skin and thereby effectively preventing infections caused by the microorganisms, are provided. The device for administering antimicrobial of the invention uses iontophoresis, and it comprises: a donor electrode (100) containing an antimicrobial; a reference electrode (110) provided as a counter electrode of the donor electrode; and a power unit (120) for applying current between the donor electrode and the reference electrode in such a manner as to allow the total amount of current applied to be 1 to 30 mA·min/cm2. The area on the skin to which the donor electrode (100) is applied is suitably 1 to 100 cm2. Thus, the catheter or injection needle insertion site on human skin is disinfected.

Abstract translation: 提供了一种用于施用抗微生物剂以杀死人皮肤上的驻留微生物并因此有效防止由微生物引起的感染的装置和组件。 用于施用本发明的抗微生物剂的装置使用离子电渗疗法，并且其包括：含有抗微生物剂的供体电极（100） 设置为供体电极的对电极的参考电极（110）; 以及用于以允许施加的电流总量为1至30mA.min / cm 2的方式在施主电极和参考电极之间施加电流的功率单元（120）。 施加施主电极（100）的皮肤上的面积适当地为1〜100cm 2。 因此，人体皮肤上的导管或注射针插入部位被消毒。

公开(公告)号：US20050175920A1

公开(公告)日：2005-08-11

申请号：US10929678

申请日：2004-08-31

Applicant: Yosuke Tsurumi ,  Hiroshi Nakazawa ,  Kazufumi Tomita ,  Shuji Sato ,  Akira Matsumoto

Inventor： Yosuke Tsurumi ,  Hiroshi Nakazawa ,  Kazufumi Tomita ,  Shuji Sato ,  Akira Matsumoto

IPC: G03G9/08 ,  G03G9/087

CPC classification number: G03G9/08782 ,  G03G9/0819 ,  G03G9/0821 ,  G03G9/0827 ,  G03G9/08795 ,  G03G9/08797

Abstract: An electrophotographic toner contains a resin, a colorant and a releasing agent. The releasing agent has a solidifying point of from 79° C. to 109° C., and one peak in an endothermic curve measured by a differential scanning calorimeter. A difference between temperature to give a maximum endothermic peak of the releasing agent and an end-set temperature of the releasing agent is within 10° C. A melt viscosity of the releasing agent at 110° C. is in a range of from 4 mPa.s to 9 mPa.s. The releasing agent in one particle of the toner forms 3 or more domains. Domains having a ratio of a major axis to a minor axis which is in a range of from 5 to 15 occupy 90% or more by number based on the total number of domains.

Abstract translation: 电子照相调色剂含有树脂，着色剂和脱模剂。 脱模剂的固化点为79℃〜109℃，通过差示扫描量热计测定吸热曲线中的一个峰。 脱模剂的最高吸热峰的温度与脱模剂的终止温度的差在10℃以内。脱模剂在110℃下的熔融粘度为4mPa .s至9 mPa.s. 调色剂的一个颗粒中的脱模剂形成3个或更多个结构域。 具有5至15范围内的长轴与短轴的比例的畴占总数的90％以上。

公开(公告)号：US20050169976A1

公开(公告)日：2005-08-04

申请号：US10510694

申请日：2003-03-28

Applicant: Kenji Mori ,  Naruhito Higo ,  Seiji Tokumoto ,  Shuji Sato ,  Kenji Sugibayashi

Inventor： Kenji Mori ,  Naruhito Higo ,  Seiji Tokumoto ,  Shuji Sato ,  Kenji Sugibayashi

IPC: A61K9/08 ,  A61K9/10 ,  A61K38/28 ,  A61K47/32 ,  A61K47/36 ,  A61M1/36 ,  A61N1/30 ,  A61N1/32 ,  A61P3/10

CPC classification number: A61N1/0416 ,  A61K38/28 ,  A61N1/0424 ,  A61N1/0432 ,  A61N1/044 ,  A61N1/30 ,  A61N1/327

Abstract: The present invention provides an insulin-administering device enabling the effective administration of insulin via a percutaneous or submucous administration route. The present device is used to percutaneously or transmucosally administer an insulin lispro represented by the structural formula indicated below, or a pharmaceutically acceptable salt thereof, using iontophoresis and electroporation.

Abstract translation: 本发明提供了能够通过经皮或粘膜下给药途径有效施用胰岛素的胰岛素给药装置。 本发明的装置用于使用离子电渗疗法和电穿孔来经皮或经粘膜内施用由下述结构式表示的赖脯胰岛素或其药学上可接受的盐。