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    Perfume composition, with a continuous aqueous phase, having a high concentration of perfume
    12.
    发明授权
    Perfume composition, with a continuous aqueous phase, having a high concentration of perfume 失效
    香料组合物，具有连续的水性相，具有高浓度的香气

    公开(公告)号：US5079227A

    公开(公告)日：1992-01-07

    申请号：US561464

    申请日：1990-08-01

    申请人： Rose-Marie Handjani ,  Arlette Zabotto ,  Alain Ribier ,  Jacqueline Griat

    发明人： Rose-Marie Handjani ,  Arlette Zabotto ,  Alain Ribier ,  Jacqueline Griat

    IPC分类号： A61K8/00 ,  A61K8/14 ,  A61Q13/00

    CPC分类号： A61Q13/00 ,  A61K8/14

    摘要： A perfume composition, with an aqueous phase, having a high concentration of perfume, which contains:a) vesicles which are obtained from at least one non-ionic lipid derived from a linear or branched polyglycerol, associated with a stabilizer present in a proportion of 1 to 10% by weight based on the lipid, the vesicles having an average diameter of between 0.01 .mu. and 1 .mu. and the lipids which form the vesicles representing 0.2 to 4% by weight of the total composition; andb) a perfume in the form of droplets having an average diameter of between 0.1 .mu. and 1 .mu. and being present in the composition in amounts of between 3 and 20% by weight based on the total composition, the total ratio of the lipid or lipids of the vesicles to the perfume being between 0.05 and 0.2.

    摘要翻译： 一种具有水相的具有高浓度香料的香料组合物，其包含：a）囊泡，其由至少一种衍生自直链或支链聚甘油的非离子脂质获得，所述非离子脂质与稳定剂相关，所述稳定剂以一定比例 1至10重量％，基于脂质，囊泡的平均直径为0.01至1微米，形成囊泡的脂质占总组合物的0.2-4重量％ 和b）平均直径为0.1至1微米的液滴形式的香料，并且基于总组合物，基于总组合物的总脂肪比例或组合物的总比例存在于组合物中的量为3至20重量％ 囊泡对香料的脂质在0.05至0.2之间。

    Anhydrous cosmetic makeup composition containing a fatty phase
    13.
    发明授权
    Anhydrous cosmetic makeup composition containing a fatty phase 失效
    含有脂肪相的无水化妆品组合物

    公开(公告)号：US06572870B2

    公开(公告)日：2003-06-03

    申请号：US09905938

    申请日：2001-07-17

    申请人： Alain Ribier ,  Jean-Thierry Simmonet ,  Dolores Miguel

    发明人： Alain Ribier ,  Jean-Thierry Simmonet ,  Dolores Miguel

    IPC分类号： A61K900

    CPC分类号： A61Q1/02 ,  A61K8/14 ,  A61K2800/31 ,  A61Q1/06 ,  Y10S514/844

    摘要： An anhydrous cosmetic makeup composition contains in addition to a fatty phase formed from oils, fatty bodies and surfactants, and optionally waxes, a vesicular lipidic phase that contains at least one ionic or nonionic amphiphilic lipid and optionally additives. The anhydrous composition also preferably contains at least one cosmetically and/or dermopharmaceutically active material. In the presence of an aqueous phase these compositions release vesicles of the vesicular lipidic phase and potentialize the activity of the cosmetically and/or dermopharmaceutically active material of the composition.

    摘要翻译： 除了由油，脂肪体和表面活性剂形成的脂肪相以及任选的蜡，包含至少一种离子或非离子两亲性脂质和任选的添加剂的囊状脂质相外，无水化妆品组合物还含有。 无水组合物还优选含有至少一种美容和/或医药活性材料。 在水相的存在下，这些组合物释放囊泡脂质相的囊泡并且可能化合物的美容和/或皮肤药物活性物质的活性。

    Oily phase in aqueous phase dispersion stabilized by cubic gel particles and method of making
    14.
    发明授权
    Oily phase in aqueous phase dispersion stabilized by cubic gel particles and method of making 失效
    油相中的水相分散体用立方凝胶颗粒稳定化及制备方法

    公开(公告)号：US6071524A

    公开(公告)日：2000-06-06

    申请号：US989853

    申请日：1997-12-12

    申请人： Alain Ribier ,  Bruno Biatry

    发明人： Alain Ribier ,  Bruno Biatry

    IPC分类号： A61K47/16 ,  A61K8/02 ,  A61K8/04 ,  A61K8/06 ,  A61K8/34 ,  A61K8/42 ,  A61K8/68 ,  A61K9/127 ,  A61Q19/00 ,  A61Q19/08 ,  B01J13/00 ,  C07C31/22 ,  C07C271/12 ,  A61K7/00 ,  A01N25/04

    CPC分类号： A61K8/042 ,  A61K8/06 ,  A61K8/062 ,  A61K8/345 ,  A61K8/42 ,  A61K8/68 ,  A61K9/1274 ,  A61Q19/00 ,  A61Q19/08 ,  Y10S514/846 ,  Y10S514/847 ,  Y10S514/939 ,  Y10S516/90

    摘要： A composition in the form a dispersion for cosmetic, dermatological or pharmaceutical use containing: (a) 60 to 98% by weight of an aqueous phase and (b) 2 to 40% by weight of an oily phase dispersed in the aqueous phase, said oily phase being dispersed and stabilized by using cubic gel particles, said particles being essentially formed of: ( ) 0.1 to 15% by weight relative to the total weight of the composition of at least one unsaturated fatty acid monoglyceride having a C.sub.16 -C.sub.22 unsaturated fatty chain in a mixture with phytanetriol, and 0.05 to 3% by weight relative to the total weight of the composition of a dispersing and stabilizing agent, said agent being a surface active substance, water-soluble at room temperature, containing a linear or branched, saturated or unsaturated, fatty chain having 8 to 22 carbon atoms. Also claimed are methods of making said compositions.

    摘要翻译： 形式为化妆品，皮肤病学或药物用途的分散体的组合物，其包含：（a）60-98重量％的水相和（b）2〜40重量％的分散在水相中的油相，所述 油相通过使用立方凝胶颗粒分散和稳定，所述颗粒基本上由以下组成：（）相对于组合物的总重量为0.1至15重量％的至少一种具有C16-C22不饱和脂肪酸的不饱和脂肪酸单甘油酯 链与植烷三醇的混合物，相对于组合物的分散稳定剂的总重量为0.05-3重量％，所述试剂是在室温下为水溶性的含有直链或支链的表面活性物质， 饱和或不饱和的，具有8至22个碳原子的脂肪链。 还要求的是制备所述组合物的方法。

    Process for preparing lipid vesicles by vaporisation of solvents
    19.
    发明授权
    Process for preparing lipid vesicles by vaporisation of solvents 失效
    通过溶剂蒸发制备脂质囊泡的方法

    公开(公告)号：US4608211A

    公开(公告)日：1986-08-26

    申请号：US587653

    申请日：1984-03-08

    申请人： Rose-Marie Handjani ,  Alain Ribier ,  Manlio M. Maurelli

    发明人： Rose-Marie Handjani ,  Alain Ribier ,  Manlio M. Maurelli

    IPC分类号： A61K9/133 ,  A61K9/127 ,  B01J13/02 ,  A61K9/50 ,  A61K9/64

    CPC分类号： A61K9/1277 ,  Y10S436/829 ,  Y10T428/2984

    摘要： A process for preparing large unilamellar lipid vesicles is disclosed which process comprises preparing unilamellar lipid vesicles having an average diameter of at least 1,000 .ANG., each of these vesicles consisting of a spheroidal lipid lamella containing a substance to be encapsulated, which process comprises dissolving one or more lipids intended to form the lamella of the vesicles in at least one water-insoluble solvent, conditioning the resulting lipid solution at a pressure P.sub.1 and at a temperature .theta..sub.1, dissolving the substance to be encapsulated in water to obtain an aqueous phase, conditioning said aqueous phase at a pressure P.sub.2 and a temperature .theta..sub.2, injecting the lipid solution into the aqueous phase at a low flow rate so as initially to form droplets and so that solvent of the lipid solution vaporises on coming into contact with the said aqueous phase, the pressure P.sub.2 being less than P.sub.1 and less than the vapor pressure of the solvent in the said droplets at the temperature .theta..sub.2.

    摘要翻译： 公开了一种制备大单层脂质囊泡的方法，该方法包括制备平均直径至少为1000的单层脂质小泡，这些囊泡由包含待包被物质的球状脂质薄片组成，该方法包括将一个或多个 更多的脂质旨在在至少一种水不溶性溶剂中形成泡囊的薄片，在压力P1和温度θ下调节所得脂质溶液，将待包封的物质溶解在水中以获得水相，调理 所述水相在压力P2和温度θ2下，以低流速将脂质溶液注入水相中，以便最初形成液滴，使得脂质溶液的溶剂在与所述水相接触时蒸发 压力P2小于P1且小于t处所述液滴中溶剂的蒸气压 温度θ2。