公开(公告)号：US20160016170A1

公开(公告)日：2016-01-21

申请号：US14335027

申请日：2014-07-18

Applicant: Tecan Trading AG

Inventor： Tiffany LAY ,  Daniel HOFFMEYER ,  Anne R. KOPF-SILL

IPC: B01L3/00 ,  G01N1/10

CPC classification number: B01L3/502792 ,  B01L3/0275 ,  B01L3/50273 ,  B01L2200/027 ,  B01L2300/0816 ,  B01L2300/161 ,  B01L2400/0427

Abstract: A disposable cartridge configured as a digital microfluidics system for manipulating samples in liquid portions having a cartridge accommodation site and a central control unit for controlling selection of individual electrodes of an electrode array located at the site and for providing plural electrodes with individual voltage pulses for manipulating liquid portions by electrowetting. The cartridge has a hydrophobic working surface and a rigid cover with a second hydrophobic surface, the hydrophobic surfaces facing each other and being separated in parallel planes by a gap. The cartridge has plural pipetting guides for safe entering/withdrawing liquids into/from the gap with a pipette tip. At least one of the pipetting guides provides an abutting surface sealingly admittable by a counter surface of a pipette tip, located at a pipetting orifice that reaches through the rigid cover, and configured to prevent a pipette tip from touching the hydrophobic working surface.

Abstract translation: 一种被配置为数字微流体系统的一次性盒，用于在具有盒容纳位置的液体部分中操作样品，并且控制中央控制单元，用于控制位于该位置处的电极阵列的各个电极的选择，并且为多个电极提供用于操纵的各个电压脉冲 液体部分通过电润湿。 所述筒具有疏水性工作表面和具有第二疏水性表面的刚性盖，所述疏水性表面彼此相对并且在平行的平面上被间隔开。 药筒具有多个移液引导件，用于以移液管吸头将液体安全地进入/从间隙排出。 移液引导件中的至少一个提供了通过移液管尖端的相对表面密封地附着的邻接表面，该移液管尖端位于移动孔口处，该移液孔口通过刚性覆盖物，并且构造成防止移液管尖端接触疏水性工作表面。

公开(公告)号：US20150331428A1

公开(公告)日：2015-11-19

申请号：US14710206

申请日：2015-05-12

Applicant: TECAN Trading AG

Inventor： Rainer KERKMANN ,  Pascal STAEHELI ,  Ho THE VINH

IPC: G05D7/06 ,  G05B19/19 ,  G06F3/0484 ,  G01N35/10 ,  G01N35/00

CPC classification number: G05D7/0623 ,  G01N35/00722 ,  G01N35/1009 ,  G01N35/1011 ,  G01N2035/0091 ,  G05B19/19 ,  G05B19/409 ,  G05B2219/2601 ,  G05B2219/40188 ,  G06F3/04842

Abstract: A method for defining an automated process which is to be carried out in a liquid handling system, wherein the liquid handling system comprises an outlet element (e.g. a pipette) for aspirating and/or dispensing a liquid volume, a numerically controlled movement apparatus for carrying out movements in connection with the aspiration/and or dispensing, and a controller for controlling the process, having the following steps: using a graphic user interface in order to enable the user to predetermine parameters which are to be used by the liquid handling system when carrying out one or several substeps of the process, wherein at least a first parameter is dependent on a second parameter in such a way that the first parameter is adjusted automatically by the system if the second parameter changes.

Abstract translation: 一种用于限定要在液体处理系统中进行的自动化过程的方法，其中所述液体处理系统包括用于吸入和/或分配液体体积的出口元件（例如移液管），用于承载的数控运动装置 以及用于控制过程的控制器，具有以下步骤：使用图形用户界面，以便使用户能够预先确定由液体处理系统使用的参数，当时 执行该过程的一个或多个子步骤，其中至少第一参数取决于第二参数，使得如果第二参数改变，则第一参数由系统自动调整。

公开(公告)号：US09120096B2

公开(公告)日：2015-09-01

申请号：US14571914

申请日：2014-12-16

Applicant: TECAN TRADING AG

Inventor： Marc N. Feiglin ,  Joseph A. Mamone ,  Michael Franklin ,  Timothy Francis Lee

IPC: G01N27/447 ,  B01L3/00 ,  B01L3/02 ,  B01F13/00 ,  B01L7/00 ,  C12Q1/68 ,  G01N27/453

CPC classification number: B01L3/502792 ,  B01F13/0071 ,  B01F13/0076 ,  B01F2215/0037 ,  B01L3/0268 ,  B01L3/502715 ,  B01L3/527 ,  B01L7/525 ,  B01L2200/027 ,  B01L2200/0605 ,  B01L2200/10 ,  B01L2200/16 ,  B01L2300/0636 ,  B01L2300/0819 ,  B01L2300/1822 ,  B01L2300/1883 ,  B01L2400/0409 ,  B01L2400/0415 ,  B01L2400/0427 ,  B01L2400/0475 ,  C12Q1/686 ,  G01N27/447 ,  G01N27/44756 ,  G01N27/453 ,  C12Q2563/143 ,  C12Q2563/149 ,  C12Q2563/159

Abstract: A biological sample processing system (1) includes a liquid droplet manipulation instrument (20) with an electrode array (21) for inducing a movement of a liquid droplet (19) by electrowetting; a substrate (22); and a control unit (23). An electrode selector (34) of the control unit (23) is configured to individually select and provide each electrode (35) of the electrode array (21) with a voltage. The control unit (23) includes a central processing unit (36) for individually selecting at least one electrode (35) and for providing the selected electrode(s) (35) with an individual voltage pulse. The biological sample processing system (1) also includes a cartridge (40) with a container (2).

Abstract translation: 生物样品处理系统（1）包括具有电极阵列（21）的液滴操作仪器（20），用于通过电润湿来诱导液滴（19）的移动; 衬底（22）; 和控制单元（23）。 控制单元（23）的电极选择器（34）被配置为单独地选择并提供电极阵列（21）的每个电极（35）。 控制单元（23）包括一个中央处理单元（36），用于分别选择至少一个电极（35），并为所选择的电极（35）提供一个单独的电压脉冲。 生物样品处理系统（1）还包括具有容器（2）的盒（40）。

公开(公告)号：US20140200683A1

公开(公告)日：2014-07-17

申请号：US13739455

申请日：2013-01-11

Applicant: TECAN TRADING AG

Inventor： Mark MA

IPC: G05B15/02

CPC classification number: G05B15/02 ,  B01L3/0293 ,  G01N35/1011 ,  G01N35/109 ,  G01N2035/1076 ,  G05B19/0426 ,  G05B2219/25482

Abstract: A laboratory system and a method for controlling a laboratory system comprises multiple subsystems; each subsystem being configured to receive and carry out a command; and a master control device configured to process command groups and/or command(s) within the same command group simultaneously; to process command groups and/or command(s) of different command groups sequentially; and within a command group, to process command group(s) and/or command(s) grouped into a command group before processing other commands command group(s) and/or command(s).

Abstract translation: 实验室系统和控制实验室系统的方法包括多个子系统; 每个子系统被配置为接收和执行命令; 以及主控制装置，被配置为同时处理同一命令组内的命令组和/或命令; 按顺序处理不同命令组的命令组和/或命令; 并在命令组内处理在处理其他命令组和/或命令之前分组到命令组中的命令组和/或命令。

公开(公告)号：US20140036070A1

公开(公告)日：2014-02-06

申请号：US13954158

申请日：2013-07-30

Applicant: Tecan Trading AG

Inventor： Simon M. Eckard ,  Nikolaus Ingenhoven

IPC: G06K9/00

CPC classification number: G06K9/00624 ,  G06T7/74 ,  G06T2207/20104

Abstract: A method of detecting an original arrangement of laboratory articles of a laboratory work station records reference digital images with a digital camera. An image is displayed and visible regions with characteristic features are selected by a user within an input device. Reference image sections and corresponding reference image parameter files are produced and stored. A current arrangement of laboratory articles is compared with a previously recorded original arrangement. Detection of the current arrangement occurred by recording current digital images with a digital camera and creating current image sections defined by X/Y parameters of the reference image parameter files from the current digital images. A computer-based comparison of the processed current image sections with the processed reference image sections occurred and an analysis of this comparison and the display of agreements, deviations and errors is found.

Abstract translation: 检测实验室工作站的实验室物品的原始布置的方法用数字照相机记录参考数字图像。 显示图像，并且用户在输入设备内选择具有特征特征的可见区域。 生成并存储参考图像部分和对应的参考图像参数文件。 将现有的实验室物品安排与以前记录的原始安排进行比较。 通过使用数字照相机记录当前数字图像并且从当前数字图像创建由参考图像参数文件的X / Y参数定义的当前图像部分来发生当前布置的检测。 发生了处理过的当前图像部分与经处理的参考图像部分的基于计算机的比较，并且发现了该比较的分析以及协议，偏差和错误的显示。

公开(公告)号：US20130126552A1

公开(公告)日：2013-05-23

申请号：US13736658

申请日：2013-01-08

Applicant: Tecan Trading AG

Inventor： Nikolaus INGENHOVEN ,  Robert LIEBHARD ,  Adi ZUPPIGER ,  Werner HALG

IPC: G01N1/14

CPC classification number: G01N1/14 ,  B01L3/021 ,  B01L2200/143 ,  B01L2200/146 ,  B01L2400/0487 ,  G01N35/1016 ,  G01N2035/1025 ,  Y10T436/11 ,  Y10T436/113332 ,  Y10T436/115831 ,  Y10T436/2575

Abstract: A method of selecting pipetting parameters of a pipetting device for dispensing or pipetting a specific volume of a liquid sample, includes a fluid column of a fluid chamber of the pipetting device set into oscillation at the beginning of the aspiration, the pressure is monitored with the pressure transducer in the fluid chamber, and the pressure changes generated during aspiration into measuring signals are recorded. These measuring signals are processed by a computer or micro-processor and reproduced as a pressure curve, which is characteristic for the fluid column with the aspirated liquid sample, and which is compared with known pressure curves. Based on this comparison, pipetting parameters of the pipetting device are selected for the dispense or for pipetting a specific volume of the liquid sample. Selectable pipetting parameters include a speed of a movement of a pump piston of the pipetting device.

Abstract translation: 选择用于分配或吸移特定体积的液体样品的移液装置的移液参数的方法包括在抽吸开始时设置成振荡的移液装置的流体室的流体柱，压力由 记录在流体室中的压力传感器，并且记录在抽吸期间产生的测量信号中的压力变化。 这些测量信号由计算机或微处理器处理并作为压力曲线再现，该压力曲线是具有吸入液体样品的流体柱的特征，并且与已知的压力曲线进行比较。 基于该比较，选择移液装置的移液参数用于分配或吸移特定体积的液体样品。 可选择的移液参数包括移液装置的泵活塞的移动速度。

公开(公告)号：US20030152491A1

公开(公告)日：2003-08-14

申请号：US10378795

申请日：2003-03-04

Applicant: Tecan Trading AG.

Inventor： Gregory J. Kellogg ,  Bruce L. Carvalho

IPC: G01N001/00 ,  B01F001/00 ,  B01L003/02

CPC classification number: B01L3/50273 ,  A63B63/083 ,  B01F5/0647 ,  B01F13/0059 ,  B01F15/0201 ,  B01F15/0233 ,  B01L3/5025 ,  B01L3/5027 ,  B01L3/502715 ,  B01L3/502723 ,  B01L3/502738 ,  B01L7/00 ,  B01L7/525 ,  B01L2200/0605 ,  B01L2300/0806 ,  B01L2300/0864 ,  B01L2300/0867 ,  B01L2300/0874 ,  B01L2300/10 ,  B01L2300/1805 ,  B01L2400/0406 ,  B01L2400/0409 ,  B01L2400/0677 ,  B01L2400/0688 ,  B01L2400/088 ,  G01N21/07 ,  G01N35/00069 ,  G01N2035/00495 ,  G01N2035/00504 ,  G01N2035/00514 ,  G01N2035/00524 ,  Y10T436/111666

Abstract: This invention relates to methods and apparatus for performing microanalytic and microsynthetic analyses and procedures. The invention particularly provides microsystem platforms for achieving efficient mixing of one or a plurality of fluids on the surface of the platform when fluid flow is motivated by centripetal force produce by rotation.

公开(公告)号：US12290804B2

公开(公告)日：2025-05-06

申请号：US17294853

申请日：2018-12-20

Applicant: TECAN TRADING AG

Inventor： Patrick Kinney ,  Sujata Iyer ,  Philipp Ott ,  Adrian Sager

IPC: B01L3/02 ,  C12Q1/6806 ,  G01N1/28 ,  G01N1/30 ,  G01N35/10 ,  G01N1/31

Abstract: A method of treating an isolated area of a sample with a liquid is disclosed. The method has the steps of generating an isolated area of a sample by a first fluid reservoir where the first fluid reservoir enclosing a distal end of a second fluid reservoir and the isolated area of the sample being sealed towards the remaining area of the sample, bringing the isolated area of the sample into fluid connection with the second fluid reservoir, dispensing a fluid from the second fluid reservoir into the first fluid reservoir thereby generating a fluid flow on the sample at the isolated area in a first direction, and aspirating the fluid from the first fluid reservoir into the second fluid reservoir thereby generating a fluid flow on the sample at the isolated area in a second direction.

公开(公告)号：US20250093376A1

公开(公告)日：2025-03-20

申请号：US18888828

申请日：2024-09-18

Applicant: Tecan Trading AG

Inventor： Luca Frei ,  Fred Schinzel ,  Dominic Erb ,  Philipp Ott

IPC: G01N35/10 ,  G01N35/04

Abstract: A guiding frame for a laboratory automation device comprises: a bottom side for placing the guiding frame on a component of the laboratory automation device; a top side with a position detection area; and an opening for accessing a port of the component, which opening is arranged besides the position detection area. The position detection area has two recesses, each recess having two straight edges, which from a view direction onto the top side are arranged inclined with respect to each other. The bottom side comprises alignment means for aligning the guiding frame with respect to the component, the alignment means comprising a base surface for contacting a top surface of the component and/or guiding surfaces for contacting walls of the component.

公开(公告)号：USD1038431S1

公开(公告)日：2024-08-06

申请号：US29861332

申请日：2022-11-29

Applicant: Tecan Trading AG

Designer： Adrian Sager

Abstract: FIG. 1 is a side perspective view of a pipetting tip according to a first embodiment of my new design;
FIG. 2 is a top and side perspective view thereof;
FIG. 3 is a bottom plan view thereof;
FIG. 4 is a top plan view thereof;
FIG. 5 is front elevation view thereof;
FIG. 6 is a rear elevation view thereof;
FIG. 7 is a left side elevation view thereof;
FIG. 8 is a right side elevation view thereof;
FIG. 9 is a side perspective view of a pipetting tip according to a second embodiment my new design;
FIG. 10 is a top and side perspective view thereof;
FIG. 11 is a bottom plan view thereof;
FIG. 12 is a top plan view thereof;
FIG. 13 is front elevation view thereof;
FIG. 14 is a rear elevation view thereof;
FIG. 15 is a left side elevation view thereof; and,
FIG. 16 is a right side elevation view thereof.