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公开(公告)号：US20220241298A1
公开(公告)日：2022-08-04
申请号：US17471858
申请日：2021-09-10
IPC分类号： A61K31/635 , A61K47/14 , A61K47/44 , A61K9/00 , A61K9/08 , A61K47/10 , A61K9/10 , A61K31/415 , A61K47/26
摘要： The present invention relates to a stable oral liquid pharmaceutical composition of celecoxib or its pharmaceutically acceptable salts thereof. The celecoxib present in the compositions as described herein do not show any precipitation when subjected in Fasted-State Simulated Gastric Fluid (FaSSGF) at pH 2.0, temperature of 37° C.±0.5° C. and under stirring at a speed of 50 rpm at least for 60 minutes. It also relates to the process of preparing and method of using said composition of celecoxib.
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公开(公告)号：US11103517B2
公开(公告)日：2021-08-31
申请号：US15093673
申请日：2016-04-07
摘要： The present application relates to a method of orally administering once daily tablet of minocycline to a subject in need thereof, wherein said tablet is substantially free of lactose. The present application also relates to processes for preparing said once daily tablet of minocycline that provides reduced stock keeping units with improved inventory by supplying multiple doses of minocycline in single tablet.
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公开(公告)号：US10799517B2
公开(公告)日：2020-10-13
申请号：US15922353
申请日：2018-03-15
IPC分类号： A61K31/415 , A61K31/635 , A61K47/14 , A61K47/44 , A61K9/00 , A61K9/08 , A61K47/10 , A61K9/10 , A61K47/26 , C07D231/12
摘要： The present invention relates to a stable oral liquid pharmaceutical composition of celecoxib or its pharmaceutically acceptable salts thereof. The celecoxib present in the compositions as described herein do not show any precipitation when subjected in Fasted-State Simulated Gastric Fluid (FaSSGF) at pH 2.0, temperature of 37° C.±0.5° C. and under stirring at a speed of 50 rpm at least for 60 minutes. It also relates to the process of preparing and method of using said composition of celecoxib.
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公开(公告)号：US20200085775A1
公开(公告)日：2020-03-19
申请号：US16690789
申请日：2019-11-21
发明人： Yogesh Bapurao PAWAR , Kailas KHOMANE , Saurabh SRIVASTAVA , Bijay Kumar PADHI , Rajeev Singh RAGHUVANSHI
摘要： The present application relates to pharmaceutical compositions comprising retinoic acid or its derivatives such as isotretinoin and processes for preparing thereof. It also provides methods for treating acne by administering such pharmaceutical composition to a patient in need thereof.
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公开(公告)号：US20190209584A1
公开(公告)日：2019-07-11
申请号：US16242562
申请日：2019-01-08
发明人： Udhumansha UBAIDULLA , Sateesh KANDAVILLI , Ajay Sunil VAIRALE , Jeffrey A. WAYNE , Vijendra NALAMOTHU , Mistry MEGHAL , Refika Isil PAKUNLU
IPC分类号： A61K31/573 , A61K47/22 , B05B15/30 , A61K47/26 , A61K47/44 , A61K47/38 , A61K47/36 , A61K47/32 , A61K47/14 , A61K47/10 , A61K31/58 , A61K31/575 , A61K31/56 , A61K9/70 , A61K9/00 , B05B11/00 , B05B1/02 , B05B1/30 , A61K9/107
CPC分类号： A61K31/573 , A61K9/0014 , A61K9/107 , A61K9/7015 , A61K31/56 , A61K31/575 , A61K31/58 , A61K47/10 , A61K47/14 , A61K47/22 , A61K47/26 , A61K47/32 , A61K47/36 , A61K47/38 , A61K47/44 , B05B1/02 , B05B1/30 , B05B11/3045 , B05B15/30
摘要： The application provides formulations for the topical administration of an active agent comprising at least one steroid, in the form of topical sprays that are propellant-free, and/or substantially non-foaming, and/or alcohol-free. The present application also provides processes for preparing such compositions and methods of using them in management of skin diseases or disorders such as psoriasis, dermatoses, and other associated skin diseases or disorders.
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![Substituted Pyrazolo[1,5-a] Pyridine As Tropomyosin Receptor Kinase (trk) Inhibitors](/abs-image/US/2018/12/13/US20180354951A1/abs.jpg.150x150.jpg)
公开(公告)号：US20180354951A1
公开(公告)日：2018-12-13
申请号：US16101753
申请日：2018-08-13
发明人： Pradip Kumar Sasmal , Shahadat Ahmed , Ashok Tehim , Vidyadhar Paradkar , Prasanna M. Dattatreya , Nanjegowda Jagadeesh Mavinahalli
IPC分类号： C07D471/04 , A61K31/444 , A61K31/4995 , A61K31/4545 , A61K31/4725 , A61K31/496 , A61K31/4985 , A61K31/635 , A61K31/506 , A61K31/5377 , A61K31/55 , A61K31/437 , C07D519/00
CPC分类号： C07D471/04 , A61K31/437 , A61K31/444 , A61K31/4545 , A61K31/4725 , A61K31/496 , A61K31/4985 , A61K31/4995 , A61K31/506 , A61K31/5377 , A61K31/55 , A61K31/635 , C07D519/00 , Y02A50/414
摘要： The present application relates to a series of substituted pyrazolo[1,5-a]pyridine compounds, their use as tropomyosin receptor kinase (Trk) family protein kinase inhibitors, method of making and pharmaceutical compositions comprising such compounds.
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公开(公告)号：US10064875B2
公开(公告)日：2018-09-04
申请号：US15928332
申请日：2018-03-22
发明人： Udhumansha Ubaidulla , Sateesh Kandavilli , Ajay Sunil Vairale , Jeffrey A. Wayne , Vijendra Nalamothu , Mistry Meghal , Refika Isil Pakunlu
IPC分类号： A61K8/02 , A61K31/573 , B05B11/00 , B05B1/30 , B05B1/02 , A61K31/58 , A61K47/38 , A61K47/14 , A61K47/44 , A61K47/10 , A61K9/00 , A61K47/36 , B05B15/30
CPC分类号： A61K31/573 , A61K9/0014 , A61K9/107 , A61K9/7015 , A61K31/56 , A61K31/575 , A61K31/58 , A61K47/10 , A61K47/14 , A61K47/22 , A61K47/26 , A61K47/32 , A61K47/36 , A61K47/38 , A61K47/44 , B05B1/02 , B05B1/30 , B05B11/3045 , B05B15/30
摘要： The application provides formulations for the topical administration of an active agent comprising at least one steroid, in the form of topical sprays that are propellant-free, and/or substantially non-foaming, and/or alcohol-free. The present application also provides processes for preparing such compositions and methods of using them in management of skin diseases or disorders such as psoriasis, dermatoses, and other associated skin diseases or disorders.
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公开(公告)号：US20180221581A1
公开(公告)日：2018-08-09
申请号：US15941224
申请日：2018-03-30
发明人： Rajesh Kumar , Anil Namboodiripad
CPC分类号： A61M5/2033 , A61M5/3129 , A61M5/31546 , A61M5/31548 , A61M5/31553 , A61M5/31555 , A61M5/3156 , A61M5/31591 , A61M5/321 , A61M5/50 , A61M2005/206 , A61M2005/2073 , A61M2005/208 , A61M2005/3126 , A61M2205/581 , A61M2205/582 , A61M2205/583
摘要： An auto-injector device for administering a liquid pharmaceutical composition, in which an end-user can select between doses that the device is capable of delivering. The end-user choices that translate into the selected doses can be based on end-user perceived severity of symptoms, end-user weight and other such factors. In some embodiments the auto-injector is configured to administer the one chosen dose only. In other embodiments, the auto-injector can deliver second and subsequent doses up to full dose of the pharmaceutical composition disposed in the injector. The auto-injector can provide visual, audio, and tactile feedback, alone or in combination, to the user to indicate the dose selected, instructions for use, and when the dose has been administered.
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公开(公告)号：US20180008619A1
公开(公告)日：2018-01-11
申请号：US15712415
申请日：2017-09-22
CPC分类号： A61K31/635 , A61K9/0053 , A61K9/0095 , A61K9/08 , A61K9/10 , A61K31/415 , A61K47/10 , A61K47/14 , A61K47/26 , A61K47/44
摘要： The present invention relates to a stable oral liquid pharmaceutical composition of celecoxib or its pharmaceutically acceptable salts thereof. The celecoxib present in the compositions as described herein do not show any precipitation when subjected in Fasted-State Simulated Gastric Fluid (FaSSGF) at pH 2.0, temperature of 37° C.±0.5° C. and under stirring at a speed of 50 rpm at least for 60 minutes. It also relates to the process of preparing and method of using said composition of celecoxib.
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10.发明授权公开(公告)号：US09765030B2
公开(公告)日：2017-09-19
申请号：US14052954
申请日：2013-10-14
发明人： Anima Baruah , Dibyendu De , Ish Kumar Khanna , Sivaram Pillarisetti , Santanu Maitra , Christopher W. Alexander , Jennepalli Sreenu , Indu Dager , Shanavas Alikunju
IPC分类号： C07D471/04 , A61K31/437 , C07D213/73 , C07D213/74 , C07D401/12 , C07D215/38 , C07D241/20 , C07D498/04 , C07D417/12 , C07D215/14 , C07D403/12 , C07D401/04 , C07D413/12 , C07D239/78 , C07D221/04 , A61K31/47 , A61K31/4709
CPC分类号： C07D215/14 , C07D213/73 , C07D213/74 , C07D215/38 , C07D241/20 , C07D401/04 , C07D401/12 , C07D403/12 , C07D413/12 , C07D417/12 , C07D471/04 , C07D498/04
摘要： The present invention provides, among other things, new benzylamine compounds, compositions comprising benzylamine compounds, methods of making benzylamine compounds, and methods of using benzylamine compounds for treating or preventing a variety of conditions or diseases associated with lipoprotein metabolism.
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