公开(公告)号：US11773414B2

公开(公告)日：2023-10-03

申请号：US17407892

申请日：2021-08-20

申请人： Firmenich SA

发明人： Pan Li ,  Qi Wang ,  Xiu-Feng He ,  Olivier Haefliger

IPC分类号： C12N9/88 ,  C12N15/29 ,  C12N15/60 ,  C12P7/02 ,  C12P5/00

CPC分类号： C12P7/02 ,  C12N9/88 ,  C12P5/007 ,  C12Y402/03126

摘要： The present application relates to a method of producing drimenol and/or drimenol derivatives by comprising contacting at least one polypeptide with farnesyl diphosphate (FPP). The method may be performed in vitro or in vivo. Also provided are amino acid sequences of polypeptides useful in the methods and nucleic acids encoding the polypeptides described. The method further provides host cells or organisms genetically modified to express the polypeptides and useful to produce drimenol and/or derivatives of drimenol.

公开(公告)号：US10266840B2

公开(公告)日：2019-04-23

申请号：US15067641

申请日：2016-03-11

申请人： The United States of America, as represented by the Secretary of Agriculture ,  Cold Spring Harbor Laboratory

发明人： Zhanguo Xin ,  Gloria B. Burow ,  Chad M Hayes ,  John J. Burke ,  Doreen Ware ,  Yinping Jiao

IPC分类号： C12N15/29 ,  C12N15/82

摘要： The present disclosure provides nucleic acids that confer a multi-seeded phenotype when expressed in plants and uses thereof.

公开(公告)号：US10260073B2

公开(公告)日：2019-04-16

申请号：US14368556

申请日：2012-12-26

申请人： Evogene Ltd.

发明人： Avital Adato ,  Hagai Karchi

IPC分类号： C12N15/29 ,  C12N15/82 ,  C07K14/415

摘要： Provided are isolated polynucleotides and nucleic acid constructs which comprise a nucleic acid sequence at least 80% identical to a nucleic acid sequence selected form the group consisting of SEQ ID NOs: 1-219, 367-5628, 9688-9700, and 9709-9752; and isolated polypeptides which comprise an amino acid sequence at least 80% homologous to an amino acid sequence selected from the group consisting of SEQ ID NOs: 220-366, 5629-9400, 9701-9708, and 9753-9796. Also provided are transgenic cells and plants expressing same and methods of using same for increasing yield, growth rate, biomass, vigor, oil content, seed yield, fiber yield, fiber quality, nitrogen use efficiency, and/or abiotic stress of a plant.

公开(公告)号：US10227602B2

公开(公告)日：2019-03-12

申请号：US15404236

申请日：2017-01-12

申请人： OKANAGAN SPECIALTY FRUITS INC.

发明人： John Armstrong ,  William David Lane

IPC分类号： C12N9/02 ,  C12N15/82 ,  C12N15/29

摘要： A genetically modified fruit-producing plant, said plant having sufficiently reduced total Polyphenol Oxidase (PPO) activity relative to a wild type of said plant to reduce browning in the fruit of said plant relative to said wild type, wherein the reduced total PPO activity results from a reduction in activity of at least two PPO isoenzymes in said plant relative to said wild type, or a cell, seed, seedling, part, tissue, cell, fruit or progeny of said plant.

公开(公告)号：US10106586B2

公开(公告)日：2018-10-23

申请号：US14747094

申请日：2015-06-23

申请人： Ceres, Inc.

发明人： Nickolai Alexandrov ,  Vyacheslav Brover ,  Kenneth Feldmann

IPC分类号： C12N15/29 ,  C07K14/415 ,  C12N15/82 ,  C12N15/11

摘要： The present invention provides DNA molecules that constitute fragments of the genome of a plant, and polypeptides encoded thereby. The DNA molecules are useful for specifying a gene product in cells, either as a promoter or as a protein coding sequence or as an UTR or as a 3′ termination sequence, and are also useful in controlling the behavior of a gene in the chromosome, in controlling the expression of a gene or as tools for genetic mapping, recognizing or isolating identical or related DNA fragments, or identification of a particular individual organism, or for clustering of a group of organisms with a common trait.

公开(公告)号：US09879276B2

公开(公告)日：2018-01-30

申请号：US14116759

申请日：2012-05-09

申请人： Chuanqing Sun ,  Xia Zhang ,  Fengxia Liu ,  Na Wang ,  Zhen Su ,  Lubin Tan ,  Zuofeng Zhu ,  Yongcai Fu ,  Daoxin Xie

发明人： Chuanqing Sun ,  Xia Zhang ,  Fengxia Liu ,  Na Wang ,  Zhen Su ,  Lubin Tan ,  Zuofeng Zhu ,  Yongcai Fu ,  Daoxin Xie

IPC分类号： C12N15/29 ,  C12N15/82 ,  C07K14/415 ,  C12Q1/68

CPC分类号： C12N15/8273 ,  C07K14/415 ,  C12Q1/6876

摘要： The present invention provides a drought tolerance associated protein, DT1, a nucleic acid molecule encoding the DT1 protein and application thereof.

公开(公告)号：US09856512B2

公开(公告)日：2018-01-02

申请号：US14388089

申请日：2013-03-26

申请人： The Governing Council of the University of Toronto

发明人： Dario Torquato Bonetta ,  Peter John McCourt ,  Danielle Vidaurre ,  George Stamatiou

IPC分类号： C12N15/82 ,  C12N15/29 ,  C12N15/52 ,  C12Q1/54 ,  A01N37/30 ,  A01N47/34 ,  G01N33/50 ,  C12Q1/68 ,  C07K14/415

CPC分类号： C12Q1/54 ,  A01N37/30 ,  A01N47/34 ,  C07K14/415 ,  C12N15/8245 ,  C12N15/8274 ,  C12Q1/6895 ,  C12Q2600/13 ,  C12Q2600/156 ,  G01N33/5097 ,  G01N2333/91114 ,  Y02E50/17 ,  A01N25/00 ,  A01N2300/00

摘要： Described herein are compositions comprising at least one auxin transport inhibitor for pre-treating a plant or seed to increase saccharification, or saccharide release by hydrolysis, the at least one auxin transport inhibitor being in an amount effective to increase sugar release from a plant tissue by hydrolysis. Also described are plant mutations, and methods to screen for such plant mutations, having an improved sugar release phenotype. The described compositions, methods and plant mutations are particularly useful for producing biofuel crops, such as maize, to improve sugar extractability from lignocellulosic biomass and hence, the efficiency of bioethanol production overall.

公开(公告)号：US09845481B2

公开(公告)日：2017-12-19

申请号：US15055880

申请日：2016-02-29

申请人： Duke University

发明人： Matthew S. Marengo ,  Mariano A. Garcia-Blanco

IPC分类号： C12P21/06 ,  C12N15/85 ,  C12N5/04 ,  C12N5/07 ,  C12N15/00 ,  C12N15/09 ,  C12N15/11 ,  C12N15/12 ,  C12N15/29 ,  C12N15/82

CPC分类号： C12N15/85 ,  C12N2800/30 ,  C12N2830/008 ,  C12N2840/007

摘要： Synthetic regulation of gene expression is provided. In some embodiments, synthetic regulatory constructs are provided. In some embodiments, a synthetic regulatory construct expresses a heterologous gene in a selected cell type. In some embodiments, methods of expressing a heterologous gene in a selected cell type are provided.

公开(公告)号：US09732352B2

公开(公告)日：2017-08-15

申请号：US13799831

申请日：2013-03-13

申请人： Cold Spring Harbor Laboratory

发明人： Zachary Lippman ,  Soon-Ju Park

IPC分类号： C12N15/29 ,  C12N15/82 ,  A01H5/08 ,  C07K14/415 ,  A01H1/02

CPC分类号： C12N15/827 ,  A01H1/02 ,  A01H5/08 ,  C07K14/415 ,  C12N15/8261

摘要： Provided herein are genetically-altered Solanaceae plants, compositions related to the Solanaceae plants, and methods of making the Solanaceae plants.

公开(公告)号：US09708672B2

公开(公告)日：2017-07-18

申请号：US14114945

申请日：2012-05-02

申请人： Sally Ann Mackenzie ,  Roberto De la Rosa Santamaria

发明人： Sally Ann Mackenzie ,  Roberto De la Rosa Santamaria

IPC分类号： C12N15/29 ,  C12N15/82 ,  C12Q1/68 ,  A01H1/04 ,  C12N15/113

CPC分类号： C12Q1/6895 ,  A01H1/04 ,  C12N15/113 ,  C12N15/8218 ,  C12N15/8241 ,  C12N15/8261 ,  C12Q2600/13 ,  C12Q2600/154 ,  C12Q2600/156 ,  C12Q2600/158

摘要： The present invention provides methods for obtaining plants that exhibit useful traits by transient suppression of the MSH1 gene of the plants. Methods for identifying genetic loci that provide for useful traits in plants and plants produced with those loci are also provided. In addition, plants that exhibit the useful traits, parts of the plants including seeds, and products of the plants are provided as well as methods of using the plants.