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公开(公告)号:US20230365873A1
公开(公告)日:2023-11-16
申请号:US18026196
申请日:2021-09-15
IPC分类号: C10G29/22 , C07C43/178 , C07C39/11 , C02F1/68
CPC分类号: C10G29/22 , C07C43/1783 , C07C39/11 , C02F1/683 , C10G2300/202 , C10G2300/80 , C02F2101/101
摘要: In a reaction product of at least one phenol compound with aldehyde(s), the phenol compound(s) reply to formula (II): wherein-R represents a hydrogen atom or a hydrocarbyl group comprising from 1 to 30 carbon atoms, -x is 1 or 2, -R1 is a linear alkyl or alkenyl group having 15 carbon atoms if x is 1, -R1 is hydrogen if x is 2, -R2 represents a hydrogen atom or a hydrocarbyl group comprising from 1 to 30 carbon atoms, and its use as a hydrogen sulphide and/or mercaptans scavenger in hydrocarbon compositions and in water-based compositions such as water-based drilling fluids.
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公开(公告)号:US10942146B2
公开(公告)日:2021-03-09
申请号:US15477747
申请日:2017-04-03
申请人: Robert Bosch GmbH
发明人: Christopher Johnson , Sam Kavusi , Nadezda Fomina , Habib Ahmad , Autumn Maruniak , Christoph Lang , Ashwin Raghunathan
IPC分类号: G01N27/416 , C07C39/11 , C07C39/10 , C07C43/225 , C07C43/23 , C07C43/178 , C07C43/205 , C07C37/07 , C07C45/42 , C07C41/30 , C07C41/24 , C07C41/01 , C07C46/06 , C07C37/00 , G01N27/30 , G01N27/327 , C12Q1/00 , G01N33/543 , C07C49/82 , C07C49/84
摘要: Device and methods for use in a biosensor comprising a multisite array of test sites, the device and methods being useful for modulating the binding interactions between a (biomolecular) probe or detection agent and an analyte of interest by modulating the pH or ionic gradient near the electrodes in such biosensor. An electrochemically active agent that is suitable for use in biological buffers for changing the pH of the biological buffers. Method for changing the pH of biological buffers using the electrochemically active agents. The methods of modulating the binding interactions provided in a biosensor, analytic methods for more accurately controlling and measuring the pH or ionic gradient near the electrodes in such biosensor, and analytic methods for more accurately measuring an analyte of interest in a biological sample.
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公开(公告)号:US10941098B2
公开(公告)日:2021-03-09
申请号:US16380769
申请日:2019-04-10
申请人: Unigen, Inc.
发明人: Sandip K. Nandy , Jiyun Liu , Alexandre Mikhailovitch Nesterov , Carmen Hertel , Abeysinghe Arrachchigae Papmapiya
IPC分类号: C07C43/295 , A23B7/154 , A23L3/3481 , A61K8/49 , A61Q19/02 , C07C39/11 , C07C39/15 , C07C43/23 , C07C45/67 , C07C45/74 , C07C49/83 , C07D213/30 , C07D307/12 , C07D307/42 , C07D317/54 , A61K8/34 , A61K31/09 , A61K31/341 , A61K31/357 , A61K31/4406 , A61Q19/08 , C07D213/64 , C07D263/57
摘要: The present invention is directed to inhibitors of tyrosinase, pharmaceutical compositions comprising such tyrosinase inhibitors, and methods of making and using the same. Specifically, included in the present invention are compositions of matter comprised of at least one 2,4-dihydroxybenzene analog, which inhibit the activity of tyrosinase and which inhibit the overproduction of melanin.
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公开(公告)号:US10457619B2
公开(公告)日:2019-10-29
申请号:US16061913
申请日:2016-12-08
申请人: L'OREAL
发明人: Xavier Marat , Amélie Gueguiniat
摘要: The present invention relates to a compound of formula (I), in particular for the use thereof for depigmenting, lightering and/or bleaching the skin. (I) In which R1 and R2, which may be identical or different, denote hydrogen, or a COR5 radical in which R5 denotes a linear C1-C10 or branched C3-C10 alkyl radical, preferably a linear C1-C6 or branched C3-C6 alkyl radical, more preferentially a linear C1-C4 alkyl radical, R3 denotes a linear C1-C6 or branched C3-C6 alkyl radical, preferably a linear C1-C4 or branched C3-C4 alkyl radical, and R4 denotes H, a linear C1-C6 or branched C3-C6 alkyl radical, or a COR5 radical, and also the salts thereof, the solvates thereof and the optical isomers thereof, and the racemic mixtures thereof, alone or as a mixture. The present invention also relates to the novel compounds (I) and also to the process for preparing same and to a cosmetic process for depigmenting the skin using such compounds (I).
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公开(公告)号:US10370315B2
公开(公告)日:2019-08-06
申请号:US15322866
申请日:2015-06-17
发明人: Elias Feghali , Thibault Cantat
摘要: A method of depolymerizing lignin and to the use of this method in the production of fuels, electronic components, plastic polymers, rubber, medicines, vitamins, cosmetic products, perfumes, foodstuffs, synthetic threads and fibers, synthetic leathers, adhesives, pesticides and fertilizers is provided. It also relates to a method of producing fuels, electronic components, plastic polymers, rubber, medicines, vitamins, cosmetic products, perfumes, foodstuffs, synthetic threads and fibers, synthetic leathers, adhesives, pesticides and fertilizers, including a step of depolymerizing lignin using the method according to the invention.
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公开(公告)号:US10259764B2
公开(公告)日:2019-04-16
申请号:US15620395
申请日:2017-06-12
申请人: Unigen, Inc.
发明人: Sandip K. Nandy , Jiyun Liu , Alexandre Mikhailovitch Nesterov , Carmen Hertel , Abeysinghe Arrachchigae Papmapiya
IPC分类号: C07C43/295 , A61K8/34 , A61K8/49 , C07C39/15 , C07C39/11 , A61Q19/02 , C07D213/64 , A61Q19/08 , C07D263/57 , A61K31/09 , A61K31/341 , A61K31/357 , A61K31/4406 , A23L3/3481 , A23B7/154 , C07D307/42 , C07D307/12 , C07D213/30 , C07C49/83 , C07C45/74 , C07C45/67 , C07C43/23 , C07D317/54
摘要: The present invention is directed to inhibitors of tyrosinase, pharmaceutical compositions comprising such tyrosinase inhibitors, and methods of making and using the same. Specifically, included in the present invention are compositions of matter comprised of at least one 2,4-dihydroxybenzene analog, which inhibit the activity of tyrosinase and which inhibit the overproduction of melanin.
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公开(公告)号:US10011549B2
公开(公告)日:2018-07-03
申请号:US14792553
申请日:2015-07-06
申请人: Robert Bosch GmbH
发明人: Christopher Johnson , Sam Kavusi , Nadezda Fomina , Habib Ahmad , Autumn Maruniak , Christoph Lang , Ashwin Raghunathan
IPC分类号: G01N27/327 , C07C49/84 , C12Q1/00 , G01N33/543 , C07C37/07 , C07C39/10 , C07C41/24 , C07C41/30 , C07C43/178 , C07C43/205 , C07C45/42 , C07C49/82 , G01N27/30 , C07C39/11 , C07C43/225 , C07C43/23
CPC分类号: G01N27/4167 , C07C37/00 , C07C37/07 , C07C39/10 , C07C39/11 , C07C41/01 , C07C41/24 , C07C41/30 , C07C43/1783 , C07C43/2055 , C07C43/225 , C07C43/23 , C07C45/42 , C07C46/06 , C07C49/82 , C07C49/84 , C12Q1/001 , C12Q1/004 , G01N27/302 , G01N27/327 , G01N27/3275 , G01N27/4163 , G01N33/5438
摘要: Device and methods for use in a biosensor comprising a multisite array of test sites, the device and methods being useful for modulating the binding interactions between a (biomolecular) probe or detection agent and an analyte of interest by modulating the pH or ionic gradient near the electrodes in such biosensor. An electrochemically active agent that is suitable for use in biological buffers for changing the pH of the biological buffers. Method for changing the pH of biological buffers using the electrochemically active agents. The methods of modulating the binding interactions provided in a biosensor, analytic methods for more accurately controlling and measuring the pH or ionic gradient near the electrodes in such biosensor, and analytic methods for more accurately measuring an analyte of interest in a biological sample.
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公开(公告)号:US08017815B2
公开(公告)日:2011-09-13
申请号:US12528554
申请日:2008-02-28
申请人: Manfred Breuninger , Marcel Joray
发明人: Manfred Breuninger , Marcel Joray
CPC分类号: C07C45/64 , C07C37/002 , C07C39/11 , C07C45/46 , C07C45/80 , C07C45/81 , C07C49/825 , C07C49/82
摘要: Process for the preparation of hydroxytyrosol, characterized by reacting 4-chloroacetyl-catechol with a metal formate and formic acid in an aqueous solvent optionally containing a lower alkanol and catalytically hydrogenating the 4-hydroxyacetyl-catechol obtained in the presence of a precious metal, preferably on a carrier.
摘要翻译: 羟基酪醇的制备方法,其特征在于使4-氯乙酰基邻苯二酚与金属甲酸盐和甲酸在含有低级链烷醇的水性溶剂中反应,并在贵金属存在下催化氢化得到的4-羟基乙酰基邻苯二酚 在运营商
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公开(公告)号:US20100324343A1
公开(公告)日:2010-12-23
申请号:US12528554
申请日:2008-02-28
申请人: Manfred Breuninger , Marcel Joray
发明人: Manfred Breuninger , Marcel Joray
IPC分类号: C07C39/11 , C07C29/136 , C07C39/10
CPC分类号: C07C45/64 , C07C37/002 , C07C39/11 , C07C45/46 , C07C45/80 , C07C45/81 , C07C49/825 , C07C49/82
摘要: Process for the preparation of hydroxytyrosol, characterized by reacting 4-chloroacetyl-catechol with a metal formate and formic acid in an aqueous solvent optionally containing a lower alkanol and catalytically hydrogenating the 4-hydroxyacetyl-catechol obtained in the presence of a precious metal, preferably on a carrier.
摘要翻译: 羟基酪醇的制备方法,其特征在于使4-氯乙酰基邻苯二酚与金属甲酸盐和甲酸在含有低级链烷醇的水性溶剂中反应,并在贵金属存在下催化氢化得到的4-羟基乙酰基邻苯二酚 在运营商
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公开(公告)号:US20100130621A1
公开(公告)日:2010-05-27
申请号:US12595984
申请日:2008-04-17
CPC分类号: A23L2/52 , A23L33/105 , A23V2002/00 , A23V2200/302 , A23V2250/2132
摘要: The present invention is directed to the use of (a composition comprising) hydroxytyrosol as anti-aging agent. The composition, to which the present invention is also directed, does essentially not comprise resveratrol and is administered orally to animals. The present invention is further directed to anti-aging methods. “Anti-aging” meaning in the context of the present invention: retarding the aging processes in said animals, improving age-related physiological deficits in said animals and/or promoting a healthy aging in said animals.
摘要翻译: 本发明涉及(含有羟基酪醇的组合物)作为抗老化剂的用途。 本发明也涉及的组合物基本上不包含白藜芦醇,并且经口给予动物。 本发明进一步涉及抗衰老方法。 在本发明的上下文中,“抗衰老”意义:延缓所述动物的老化过程,改善所述动物的年龄相关生理缺陷和/或促进所述动物的健康老化。
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