公开(公告)号：US20230218562A1

公开(公告)日：2023-07-13

申请号：US18124697

申请日：2023-03-22

申请人： SK BIOPHARMACEUTICALS CO., LTD.

发明人： Young-Soon KANG ,  Jin-Yong CHUNG ,  Cheol-Young MAENG ,  Han-Ju YI ,  Ki-Ho LEE ,  Joon HEO ,  Eun-Hee CHAE ,  Yu-Jin SHIN

IPC分类号： C07C275/60 ,  A61K45/06 ,  A61P25/26

CPC分类号： C07C275/60 ,  A61K45/06 ,  A61P25/26

摘要： The present disclosure provides a compound represented by Formula (I) and a pharmaceutically acceptable salt which are effective as a dopamine reuptake inhibitor and a method of using the compound:






wherein X is independently halo, alkyl, alkoxy or nitro; m is 0, 1, 2, 3 or 4; n is 1 or 2; R1 and R2 are independently H— or alkyl; R3 is H—, alkyl or aralkyl; and R4 is H— or aryl.

公开(公告)号：US11492441B2

公开(公告)日：2022-11-08

申请号：US16190637

申请日：2018-11-14

申请人： CANON KABUSHIKI KAISHA

发明人： Seiji Okada

IPC分类号： C08G18/81 ,  C07C275/60 ,  C08G18/38 ,  C07C275/14 ,  B33Y70/00 ,  C08G18/67 ,  C08G18/48 ,  C08G18/24 ,  C08G18/78 ,  C08G18/28 ,  C08F290/06 ,  C08G18/73 ,  C08G18/10 ,  C08G18/32 ,  C08G18/44 ,  C08G18/42 ,  B29K96/04 ,  B29C64/135 ,  B33Y10/00 ,  B29K75/00

摘要： Provided is a photo-curable composition capable of creating a three-dimensional object excellent in both of: stiffness and strength; and toughness. Specifically, provided is a photo-curable composition including: a blocked isocyanate represented by the general formula (1); a chain extender; and a photo-radical generator: wherein, in the general formula (1), A1 to A4 each independently represent a structure represented by the following general formula (2), and B represents a structure represented by the following general formula (3)

公开(公告)号：US10888542B2

公开(公告)日：2021-01-12

申请号：US16654168

申请日：2019-10-16

申请人： SK BIOPHARMACEUTICALS CO., LTD.

发明人： Young-Soon Kang ,  Jin-Yong Chung ,  Cheol-Young Maeng ,  Han-Ju Yi ,  Ki-Ho Lee ,  Joon Heo ,  Eun-Hee Chae ,  Yu-Jin Shin

IPC分类号： A61K31/325 ,  C07C275/60 ,  A61K9/00 ,  A61K31/27 ,  A61P25/00 ,  A61K45/06

摘要： The present disclosure provides a compound represented by Formula (I) and a pharmaceutically acceptable salt which are effective as a dopamine reuptake inhibitor and a method of using the compound: wherein X is independently halo, alkyl, alkoxy or nitro; m is 0, 1, 2, 3 or 4; n is 1 or 2; R1 and R2 are independently H— or alkyl; R3 is H—, alkyl or aralkyl; and R4 is H— or aryl.

公开(公告)号：US20190247356A1

公开(公告)日：2019-08-15

申请号：US16395422

申请日：2019-04-26

申请人： SK BIOPHARMACEUTICALS CO., LTD.

发明人： Young-Soon KANG ,  Jin-Yong CHUNG ,  Cheol-Young MAENG ,  Han-Ju YI ,  Ki-Ho LEE ,  Joon HEO ,  Eun-Hee CHAE ,  Yu-Jin SHIN

IPC分类号： A61K31/325 ,  A61P25/00 ,  A61K9/00 ,  C07C275/60 ,  A61K45/06 ,  A61K31/27

CPC分类号： A61K31/325 ,  A61K9/0053 ,  A61K31/27 ,  A61K45/06 ,  A61P25/00 ,  C07C275/60

摘要： The present disclosure provides a compound represented by Formula (I) and a pharmaceutically acceptable salt which are effective as a dopamine reuptake inhibitor and a method of using the compound: wherein X is independently halo, alkyl, alkoxy or nitro; m is 0, 1, 2, 3 or 4; n is 1 or 2; R1 and R2 are independently H— or alkyl; R3 is H—, alkyl or aralkyl; and R4 is H— or aryl.

公开(公告)号：US20180085337A1

公开(公告)日：2018-03-29

申请号：US15805293

申请日：2017-11-07

申请人： SK BIOPHARMACEUTICALS CO., LTD.

发明人： Young-Soon KANG ,  Jin-Yong CHUNG ,  Cheol-Young MAENG ,  Han-Ju YI ,  Ki-Ho LEE ,  Joon HEO ,  Eun-Hee CHAE ,  Yu-Jin SHIN

IPC分类号： A61K31/325 ,  A61K31/27 ,  A61K45/06 ,  C07C275/60 ,  A61K9/00

CPC分类号： A61K31/325 ,  A61K9/0053 ,  A61K31/27 ,  A61K45/06 ,  A61P25/00 ,  C07C275/60

摘要： The present disclosure provides a compound represented by Formula (I) and a pharmaceutically acceptable salt which are effective as a dopamine reuptake inhibitor and a method of using the compound: wherein X is independently halo, alkyl, alkoxy or nitro; m is 0, 1, 2, 3 or 4; n is 1 or 2; R1 and R2 are independently H— or alkyl; R3 is H—, alkyl or aralkyl; and R4 is H— or aryl.

公开(公告)号：US09394244B2

公开(公告)日：2016-07-19

申请号：US14430934

申请日：2013-10-22

申请人： BASF SE

发明人： Eugene Valentine Sitzmann ,  David Trumbo ,  Mervin Wood

IPC分类号： C08F2/50 ,  C08F2/46 ,  C08G61/04 ,  C07C275/60 ,  C07D401/14 ,  C07C273/18 ,  C07D211/94 ,  C07D251/24 ,  C08F222/22 ,  C09D135/02 ,  C07D249/20 ,  C07D307/62

CPC分类号： C07C275/60 ,  C07C273/1854 ,  C07D211/94 ,  C07D249/20 ,  C07D251/24 ,  C07D307/62 ,  C07D401/14 ,  C08F222/22 ,  C08G18/282 ,  C08G18/2825 ,  C08G18/73 ,  C08G18/755 ,  C08G18/7837 ,  C08G18/8166 ,  C09D135/02

摘要： Disclosed are functional polyallophanate oligomers comprising ethylenically unsaturated groups and polymer stabilizer groups selected from hindered amine light stabilizers, ultraviolet light absorbers, antioxidants and dihydrocarbylhydroxylamines. The ethylenically unsaturated groups and the polymer stabilizer groups are bound to the polyallophanate oligomers through allophanate and/or carbamate groups. The polyallophanate oligomers are useful in curable coatings, inks and varnishes. The present polyallophanate oligomers are derived from a) organic polyisocyanates, b) compounds containing at least one isocyanate reactive group and at least one ethylenically unsaturated group and c) polymer stabilizers containing at least one isocyanate reactive group.

摘要翻译： 公开了包含烯键式不饱和基团和选自受阻胺光稳定剂，紫外光吸收剂，抗氧化剂和二烃基羟胺的聚合物稳定剂基团的官能化聚山梨酸酯低聚物。 烯属不饱和基团和聚合物稳定剂基团通过脲基甲酸酯和/或氨基甲酸酯基团结合到多聚叶酸酯低聚物。 聚对苯二甲酸乙二醇酯低聚物可用于可固化涂料，油墨和清漆。 本发明的聚阴离子低聚物衍生自a）有机多异氰酸酯，b）含有至少一个异氰酸酯反应性基团和至少一个烯键式不饱和基团的化合物，和c）含有至少一个异氰酸酯反应性基团的聚合物稳定剂。

公开(公告)号：US20150246874A1

公开(公告)日：2015-09-03

申请号：US14633388

申请日：2015-02-27

申请人： SK BIOPHARMACEUTICALS CO., LTD.

发明人： Young-Soon KANG ,  Jin-Yong CHUNG ,  Cheol-Young MAENG ,  Han-Ju YI ,  Ki-Ho LEE ,  Joon HEO ,  Eun-Hee CHAE ,  Yu-Jin SHIN

IPC分类号： C07C275/60 ,  A61K31/27 ,  A61K45/06

CPC分类号： A61K31/325 ,  A61K9/0053 ,  A61K31/27 ,  A61K45/06 ,  C07C275/60

摘要： The present disclosure provides a compound represented by Formula (I) and a pharmaceutically acceptable salt which are effective as a dopamine reuptake inhibitor and a method of using the compound: wherein X is independently halo, alkyl, alkoxy or nitro; m is 0, 1, 2, 3 or 4; n is 1 or 2; R1 and R2 are independently H— or alkyl; R3 is H—, alkyl or aralkyl; and R4 is H— or aryl.

摘要翻译： 本公开内容提供了作为多巴胺再摄取抑制剂有效的由式（I）表示的化合物和药学上可接受的盐以及使用该化合物的方法：其中X独立地为卤素，烷基，烷氧基或硝基; m为0,1,2,3或4; n为1或2; R1和R2独立地为H或烷基; R3是H，烷基或芳烷基; R4是H或芳基。

公开(公告)号：US07268202B2

公开(公告)日：2007-09-11

申请号：US10489913

申请日：2002-09-17

申请人： Shinichiro Watanabe ,  Kunio Naoi

发明人： Shinichiro Watanabe ,  Kunio Naoi

IPC分类号： C08G18/78 ,  C08G18/79 ,  C08G18/80 ,  C09D175/04 ,  C07C275/60

CPC分类号： C09D175/04 ,  C08G18/6229 ,  C08G18/7837 ,  C08G18/8016 ,  C08G18/8064 ,  Y10T428/31551

摘要： A polyisocyanate composition comprising an allophanate group, which is obtained from an aliphatic diisocyanate(s), wherein in a state substantially free of a solvent and the aliphatic diisocyanate(s), (i) the content of components having a molecular weight of 700 or less is 20-60 weight %, (ii) the ratio of weight average molecular weight to number average molecular weight is 1.20-5.00, (iii) the ratio of viscosity (unit: mPa·s) of the polyisocyanate composition at 25° C. to the number average number of functional groups of isocyanate groups is represented by the following expression: viscosity(mPa·s)/number average number of functional groups≦240.

摘要翻译： 包含由脂族二异氰酸酯获得的脲基甲酸酯基的多异氰酸酯组合物，其中在基本上不含溶剂和脂族二异氰酸酯的状态下，（i）分子量为700的组分的含量或 少于20-60重量％，（ii）重均分子量与数均分子量之比为1.20-5.00，（iii）多异氰酸酯组合物在25℃下的粘度（单位：mPa.s）的比例 相对于异氰酸酯基的官能团的数均数由下列表达式表示：<？in-line-formula description =“In-line Formulas”end =“lead”？> viscosity（mPa.s）/ number average 功能组数<= 240。<？in-line-formula description =“In-line Formulas”end =“tail”？>

公开(公告)号：US06991746B2

公开(公告)日：2006-01-31

申请号：US11072762

申请日：2005-03-04

申请人： William E. Slack ,  Hersel T. Kemp, II ,  William E. Miller

发明人： William E. Slack ,  Hersel T. Kemp, II ,  William E. Miller

IPC分类号： C07C275/60 ,  C07C269/02 ,  C07C271/66 ,  C07C273/00 ,  C07C275/62

CPC分类号： C08G18/7837

摘要： The present invention relates to a new high functionality MDI. In particular, this invention relates to polymeric allophanates based on diphenylmethane diisocyanate having an NCO group content of 12 to 30%, prepolymers thereof, and processes for the production of these compositions. The prepolymers are stable liquids having NCO group contents of about 10 to about 28%.

摘要翻译： 本发明涉及一种新的高功能MDI。 特别地，本发明涉及基于NCO基团含量为12-30％的二苯基甲烷二异氰酸酯的聚合物脲基甲酸酯，其预聚物，以及这些组合物的制备方法。 预聚物是具有约10至约28％的NCO基团含量的稳定液体。

公开(公告)号：US06878841B2

公开(公告)日：2005-04-12

申请号：US10182528

申请日：2001-01-24

申请人： Heinz-Peter Rink ,  Jochem Henkelmann ,  Werner-Alfons Jung ,  Paul J. Harris ,  Swaminathan Ramesh

发明人： Heinz-Peter Rink ,  Jochem Henkelmann ,  Werner-Alfons Jung ,  Paul J. Harris ,  Swaminathan Ramesh

IPC分类号： C07C269/04 ,  C07C271/12 ,  C07C275/60 ,  C08K5/205 ,  C08K5/21 ,  C09D179/00 ,  C09D201/02 ,  C09J7/02 ,  C09J179/00 ,  C09J201/02 ,  C07C261/00

CPC分类号： C08K5/21 ,  C07C271/12 ,  C07C275/60 ,  C08K5/205

摘要： Positionally isomeric diethyloctanediol dicarbamates and diethyloctanediol diallophanates, processes for preparing them, and their use as synthesis building blocks and constituents of adhesives, sealing compounds, and coating materials.

摘要翻译： 位置异构的二乙基辛二醇二氨基甲酸酯和二乙二醇二环戊二酸酯，它们的制备方法，以及它们作为粘合剂，密封化合物和涂料的合成结构单元和成分的用途。