摘要:
A process of preparing taurine-containing peptides of formula (I): ##STR1## comprises reacting a protected aminoacid with cysteamine or cystamine in the presence of a condensing agent, oxidizing the resulting compound and deprotection.
摘要:
Benzylidene derivatives of the formula: ##STR1## wherein n represents an integer from 1 through 4, R represents an amino radical, a monoalkylamino group containing 1 through 4 carbon atoms in the alkyl radical, a dialkylamino group containing 1 through 4 carbon atoms in each alkyl radical, or when n represents 2, 3 or 4 a group ##STR2## in which m represents 4 or 5, or a group --OM in which M represents an alkali metal or alkaline earth metal, and X.sub.1 X.sub.2, X.sub.3 and X.sub.4 each represent a hydrogen atom, a halogen atom, or an alkyl radical containing 1 through 6 carbon atoms, are new therapeutically useful compounds. They possess antidepressant, anticonvulsant, anxiolytic, analgesic, anti-inflammatory, ulcer-inhibiting, gastric antisecretory and antihypertensive properties.
摘要:
Water-soluble or water-dispersible resinous salts are prepared by `tipping` an epoxy resin with a phenol, then carrying out a Mannich reaction with an aldehyde (usually formaldehyde) and an aminosulfonic or aminophosphonic acid, followed by salt formation on the free acid groups, preferably using an aliphatic amino alcohol, e.g., 2-dimethylaminopropan-1-ol.Such salts may be crosslinked by heating in the presence of an aminoplast, a phenol-formaldehyde resin or a blocked polyisocyanate or, when the salts contain free methylol groups, by heating alone. They can be used for preparing coating compositions.
摘要:
A process for the preparation of 2-methoxy-5-methylaniline-4-sulphonic acid by contacting optionally acylated 2-methoxy-5-methylaniline with sulfuric acid or a mixture of sulfuric acid and oleum at an elevated temperature.
摘要:
A 2-alkoxyalkoxy-5-aminobenzenesulfonic acid represented by the following general formula (I): ##STR1## wherein R.sup.1 represents an alkylene group having 2 or more carbon atoms; and R.sup.2 represents an alkyl group. The compound can be used as an intermediate in the production of a dye releasing redox compound.
摘要:
Disclosed are benzidine derivatives substituted in each of the 3,3'-positions by the substituent ##STR1## wherein W is hydrogen or an alkali metal, the subscript n is zero when A is the divalent branched chain alkylene having from 2 to about 7 carbon atoms, and n is one when A is straight chain divalent alkylene with 3 or 4 carbons. Also disclosed are the corresponding derivatives wherein the sulfonyl group is replaced by the carbonyl group. Further disclosed are chromogen-reactive indicator compositions having as their chromogen constituent one of the foregoing benzidine derivatives. These compositions (1) are useful to test for a substance for which there exists a specific oxygen-oxidoreductase, such as a sugar, an amino acid, uric acid, and the like, and thus (2) contain also a peroxidase, a hydrogen-peroxide-oxidoreductase, and a specific oxygen-oxidoreductase for the specific material in the testing of which the composition is to be used.
摘要:
This invention relates to a process for the manufacture sulphonated compounds. Aromatically unsaturated amines are reacted with sulphamic acid or its derivatives at temperatures between 20.degree. and 250.degree.C in the presence of an aprotic solvent and a catalyst.
IN WHICH R IS -OH OR -NH2 ARE PREPARED BY NITRATING 1-NITRONAPHTHALENE-5-SULFONIC ACID IN OLEUM TO GIVE 1,7DINITRONAPHTHALENE-5-SULFONIC ACID, REDUCING THE LATTER TO 1,7-DIAMINONAPHTHALENE-5-SULFONIC ACID AND OPTIONALLY EXCHANGING IN KNOWN MANNER THE 1-POSITIONED AMINO GROUP FOR A HYDROXY GROUP. THESE COMPOUNDS ARE USEFUL AS INTERMEDIATES IN THE PREPARATION OF AZOMETHINE DYESTUFFS, E.G. BY CONDENSATION WITH AROMATIC ALDEHYDES.
摘要:
The invention relates to a process for the preparation of 1-amino-8-naphthol-4,6-disulphonic acid (K-acid) as the mono-alkali metal salt by reacting a mixture of naphthylaminetrisulphonic acids and/or salts thereof with an alkali metal salt solution and separating the K-acid as the mono-alkali metal salt, by acidification and crystallization. The product is a known valuable dyestuff intermediate.
摘要:
A method for removing residual cresidine from impure p-cresidine sulfonic acid which impure p-cresidine sulfonic acid contains from above two parts per billion to about 1500 parts per million of cresidine. The method comprises contacting an aqueous solution of the p-cresidine sulfonic acid with a sufficient quantity of particles of a crosslinked lipophilic porous resin for a sufficient time to reduce the concentration of p-cresidine in the cresidine sulfonic acid to less than 2 parts per billion.