公开(公告)号：US20240295556A1

公开(公告)日：2024-09-05

申请号：US18270659

申请日：2022-01-03

Applicant: VETALL LABORATORIES ,  ABC CIRCLE CO., LTD.

Inventor： Jihyun KIM ,  Miyoung YANG ,  Jeongmi KIM ,  Inseo PARK ,  Jaejun LEE

IPC: G01N33/569 ,  G01N33/543

CPC classification number: G01N33/56961 ,  G01N33/54388 ,  G01N33/56911 ,  G01N2333/195 ,  G01N2333/37 ,  G01N2469/10

Abstract: The present invention provides a simultaneous diagnosis method and a simultaneous diagnosis kit for Erwinia carotovora and Phytophthora infestans in the soil using semi-quantitative lateral flow immunoassay, for early identification and prevention of causative organisms that may cause a plant soft rot disease and a plant blight disease in the soil around a plant growth environment using semi-quantitative lateral flow immunoassay.

公开(公告)号：US20240151613A1

公开(公告)日：2024-05-09

申请号：US18281405

申请日：2022-03-11

Applicant: GOLDSWORTHY, Robert ,  GOLDSWORTH, Susan

Inventor： Robert John Goldsworthy ,  Susan Goldsworthy

IPC: G01N1/38 ,  G01N1/28 ,  G01N1/40 ,  G01N33/569

CPC classification number: G01N1/38 ,  G01N1/286 ,  G01N33/56961 ,  G01N2001/386 ,  G01N2001/4061

Abstract: A method to extract a mycotoxin, or a plurality of mycotoxins, from a sample carrier into a solvent solution. The mycotoxin may have been an initially airborne mycotoxin initially captured by a filter that functions as the sample carrier. The method may generally include the steps of at least partially immersing or wetting the sample carrier within a solvent solution carried by a vessel; agitating the sample carrier within the solvent solution to extract at least some of the mycotoxin from the sample carrier; and removing the sample carrier from the vessel.

公开(公告)号：US11754547B2

公开(公告)日：2023-09-12

申请号：US17323205

申请日：2021-05-18

Applicant: Government of the United States, as represented by the Secretary of the Air Force

Inventor： Oscar N. Ruiz ,  Thusitha S Gunasekera ,  Osman Radwan

IPC: C07K7/06 ,  G01N33/28 ,  G01N33/569 ,  G01N21/64 ,  C07K17/14

CPC classification number: G01N33/2835 ,  C07K7/06 ,  C07K17/14 ,  G01N21/6458 ,  G01N33/56911 ,  G01N33/56961

Abstract: A biorecognition element for rapid detection of fuel biocontamination. The biorecognition element is a biorecognition element selected from SEQ. ID No. 2 through SEQ. ID No. 24, SEQ. ID No. 22 through SEQ. ID No. 44, SEQ. ID No. 46 through SEQ. ID No. 57, SEQ. ID No. 59 through SEQ. ID No. 196 or SEQ. ID No. 198 through SEQ. ID No. 332.

公开(公告)号：US11740238B2

公开(公告)日：2023-08-29

申请号：US15756807

申请日：2016-09-02

Applicant: PIONEER HI-BRED INTERNATIONAL, INC.

Inventor： Kristi Ruth Harkins ,  Aaron Joseph Walck

IPC: G01N33/569 ,  G01N33/543

CPC classification number: G01N33/56961 ,  G01N33/54313

Abstract: Disclosed herein are methods and assays for the detection and/or quantification of one or more proteins or substances of interest in a sample, such as a plant, human, insect, microorganism or mammalian sample.

公开(公告)号：US20190062412A1

公开(公告)日：2019-02-28

申请号：US16172175

申请日：2018-10-26

Applicant: Dynamiker Biotechnology (Tianjin) Co., Ltd.

Inventor： Chunlong LIU ,  Jie PENG ,  Zhou ZHANG ,  Shuanzhu ZHAI ,  Ning LI ,  Yan SU ,  Zeqi ZHOU

IPC: C07K16/14 ,  G01N33/569

CPC classification number: C07K16/14 ,  C07K16/44 ,  C07K2317/31 ,  C07K2317/54 ,  C07K2317/55 ,  C07K2317/622 ,  C07K2317/626 ,  G01N33/56961 ,  G01N2333/38

Abstract: The present invention provides a hybridoma cell under the accession number CGMCC No. 13827. The hybridoma cell is capable of producing a monoclonal antibody against Aspergillus galactomannan antigen and a kit is prepared using the same. The kit provided by the present invention can specifically bind to the GM antigen, has both sensitivity and specificity of more than 95%, a detection limit of 0.85 ng/mL compared to 1 ng/mL of the existing product, and high compliance rate between the detection result and the reference reagent, and can provide more accurate and reliable detection results, so that IA can be detected early in the course of the disease and the patients can receive treatment in timely and effective manner, thereby improving the survival rate of patients. Moreover, the kit has simple and convenient operation, rapid and sensitive detection, which provides an effective tool for the quantitative detection of Aspergillus GM antigen.

公开(公告)号：US20180209974A1

公开(公告)日：2018-07-26

申请号：US15924170

申请日：2018-03-16

Applicant: DYNAMIKER BIOTECHNOLOGY (TIANJIN) CO.,LTD

Inventor： JIE PENG ,  DONGDONG SHI ,  NING LI ,  YAN SU ,  ZEQI ZHOU

IPC: G01N33/569 ,  C08B37/00 ,  C12P19/04 ,  G01N33/535

CPC classification number: G01N33/56961 ,  B01D15/3809 ,  C08B37/0003 ,  C12P19/04 ,  G01N30/02 ,  G01N33/535 ,  G01N2333/39

Abstract: The present invention discloses a preparation method of crytococcus neoformans capsular polysaccharide GXM as well as a GXM antigen immunoassay kit and an application thereof. The preparation method of the crytococcus neoformans capsular polysaccharide GXM effectively avoids the use of a toxic chemical reagent, ensures safety of operators, and also avoids environmental pollution, has high specificity, and can prepare a high-purity crytococcus neoformans capsular polysaccharide while simplifying a preparation process. The GXM antigen immunoassay kit adopts a competition method, has good sensitivity, specificity, repeatability and stability, has high recovery rate of a target compound and may provide more accurate and reliable inspection results. The kit is simple and feasible in use and operation, rapid and sensitive in detection and low in price and provides an effective tool for clinical detection of GXM.

公开(公告)号：US10000733B2

公开(公告)日：2018-06-19

申请号：US14745365

申请日：2015-06-19

Applicant: The Arizona Board of Regents on Behalf of the University of Arizona

Inventor： Anne Elizabeth Arnold ,  Kayla Arendt ,  David A. Baltrus

IPC: C12N1/14 ,  C12N1/20 ,  C12Q1/26 ,  C12Q1/34 ,  G01N33/569

CPC classification number: C12N1/14 ,  C12N1/20 ,  C12Q1/26 ,  C12Q1/34 ,  G01N33/56961 ,  G01N2333/37 ,  G01N2333/942

Abstract: Described herein are methods for the alteration and/or transfer of fungal functional traits, e.g., phenotypic activity, via the controlled transfer of endohyphal symbionts, e.g., bacteria, among fungal species. Also described are methods for the identification of endohyphal bacterial symbionts as determinants of cellulase and ligninase activity in fungi, and the use of endohyphal bacterial symbionts to alter the activity, including cellulase and ligninase activities, of the fungi. In particular, the fungi described herein are endophytic fungi, that is, fungi which colonize living, and subsequently senescent, plant tissue.

公开(公告)号：US09778259B2

公开(公告)日：2017-10-03

申请号：US13846900

申请日：2013-03-18

Applicant: Bio-Rad Innovations ,  Centre Hospitalier Universitaire de Lille ,  Universite Lille 2 Droit et Sante

Inventor： Sebastien Damiens ,  Chantal Fradin ,  Daniel Poulain ,  Boualem Sendid ,  Marc Charles Victor Tabouret

IPC: G01N33/569

CPC classification number: G01N33/56961

Abstract: The present invention concerns an in vitro method for diagnosing invasive candidiasis (IC) in a subject which comprises detecting the presence of a Candida glycan and detecting the presence of antibody directed against a protein selected from the group consisting of fructose bisphosphate aldolase (Fba1), enolase 1 (Eno1), heat shock protein 90 (Hsp90), hyphal wall protein (Hwp1), and mannoprotein 65 (Mp65) in a blood, plasma or serum sample of the subject. The invention also relates to a method of determining a suitable treatment regimen for a patient and to a kit for implanting the methods described herein.

公开(公告)号：US20170276677A1

公开(公告)日：2017-09-28

申请号：US15320283

申请日：2015-06-22

Applicant: Queensland University of Technology

Inventor： Janet Davies

IPC: G01N33/569 ,  C07K14/415 ,  G01N33/68 ,  C07K16/16 ,  A61K39/36 ,  G01N33/577

CPC classification number: G01N33/56961 ,  A61K39/36 ,  C07K14/415 ,  C07K16/16 ,  C07K2317/72 ,  G01N33/577 ,  G01N33/68 ,  G01N2800/24

Abstract: Detection of grass pollen proteins such as Pas n 1, Sor h 1 and/or Cyn d 1 for the purpose of batch standardization of compositions comprising these grass pollen proteins, such as used for desensitization to these allergenic proteins. The methods may also be suitable for detecting or measuring levels of grass pollen proteins such as Pas n 1, Sor h 1 and/or Cyn d 1 in environmental samples such as air or water. Also provided is an antibody or antibody fragment engineered to bind Pas n 1 and one or a plurality of other grass pollen proteins such as Sor h 1 and/or Cyn d 1.

公开(公告)号：US09709576B2

公开(公告)日：2017-07-18

申请号：US15248106

申请日：2016-08-26

Applicant: Hiroshima University

Inventor： Michihiro Hide ,  Takaaki Hiragun ,  Kaori Ishii ,  Shoji Mihara ,  Makiko Hiragun ,  Jens-M Schroeder

IPC: A61K39/02 ,  C07K16/14 ,  G01N33/68 ,  C07K14/375 ,  A61K39/00 ,  G01N33/569 ,  A61K38/00

CPC classification number: G01N33/6854 ,  A61K38/00 ,  A61K39/0002 ,  A61K2039/577 ,  C07K14/375 ,  C07K16/14 ,  C07K2317/76 ,  C07K2319/30 ,  G01N33/56961 ,  G01N2333/37 ,  G01N2800/20 ,  G01N2800/202 ,  G01N2800/24

Abstract: Provided are a sweat allergy antigen, an antibody capable of binding to the antigen specifically, and others, which are produced utilizing a microorganism-originated protein that exists in sweat allergy patient in a dissolved state or a partial peptide of the protein.