公开(公告)号：US11957864B2

公开(公告)日：2024-04-16

申请号：US16673347

申请日：2019-11-04

申请人： B. Braun Medical Inc.

发明人： Mike Janders ,  Mariano Mumpower ,  Benjamin R. Lane

IPC分类号： A61J3/00 ,  A61M39/22 ,  A61M39/24 ,  B01F23/45 ,  B01F23/451 ,  B01F25/00 ,  B01F25/30 ,  B01F25/31 ,  B01F33/30 ,  B01F33/301 ,  B01F33/84 ,  B01F35/71 ,  B65B3/12 ,  F16K5/04 ,  F16K11/085 ,  F16K11/22 ,  F16K31/04 ,  F16K99/00 ,  B01F101/00 ,  B01F101/06 ,  B01F101/22

CPC分类号： A61M39/223 ,  A61J3/002 ,  A61M39/24 ,  B01F23/45 ,  B01F23/451 ,  B01F25/1051 ,  B01F25/30 ,  B01F25/31 ,  B01F33/30 ,  B01F33/3017 ,  B01F33/84 ,  B01F33/846 ,  B01F35/7176 ,  B01F35/717611 ,  B01F35/71805 ,  B65B3/12 ,  F16K5/04 ,  F16K5/0407 ,  F16K5/0414 ,  F16K11/085 ,  F16K11/22 ,  F16K31/041 ,  F16K99/0013 ,  F16K99/0042 ,  A61J2200/70 ,  A61M39/22 ,  A61M2039/229 ,  B01F2101/06 ,  B01F2101/22 ,  B01F2101/2202 ,  B01F2101/2204 ,  F16K11/0856 ,  F16K2099/0084

摘要： An exemplary pharmaceutical compounding system and device for mixing materials from at least two distinct material sources can include a transfer set and junction structure that has a junction body, a first inlet port located at a first portion of the junction body, a second inlet port located at a second portion of the junction body, and an outlet port located at a third portion of the junction body. The junction structure can be configured to mix fluid received from both the first inlet port and second inlet port and to deliver the fluid to the outlet port. The junction structure can also include attachment structure located on the junction body and configured to attach the junction structure to the housing of the compounding device at a location downstream of a pump system.

公开(公告)号：US11788647B2

公开(公告)日：2023-10-17

申请号：US17259123

申请日：2019-07-11

申请人： Agilent Technologies, Inc.

发明人： Manfred Berndt

IPC分类号： F16K99/00 ,  G01N30/20 ,  F16K11/074 ,  F16K31/04

CPC分类号： F16K99/0042 ,  F16K99/0013 ,  G01N30/20 ,  F16K11/0743 ,  F16K31/043 ,  F16K2099/0084 ,  G01N2030/202

摘要： A valve arrangement includes a valve module and a base module. The valve module includes a stator and a rotor, which is rotatable relative to the stator such that at least one fluid connection is formable between the stator and the rotor. The base module includes at least a part of a force control mechanism for selectively implementing a force-releasing or force-coupling of the rotor and the stator, whereby the valve module and the base module are selectively coupleable to or decoupleable from each other.

公开(公告)号：US09970572B2

公开(公告)日：2018-05-15

申请号：US14919953

申请日：2015-10-22

申请人： DunAn Microstaq, Inc.

发明人： Parthiban Arunasalam ,  E. Nelson Fuller ,  Joe A. Ojeda, Sr.

IPC分类号： F16K31/126 ,  F16K99/00

CPC分类号： F16K99/0059 ,  F16K31/126 ,  F16K99/0042

摘要： A valve assembly is configured to regulate the flow of an isolated fluid therethrough and includes a first valve stage configured to control the flow of a first fluid through a first fluid circuit, and a second valve stage configured to control the flow of a second fluid through a second fluid circuit. The first valve stage is connected to the second valve stage such that the first fluid acts on the second valve stage to move the second valve stage between open and closed positions. The second fluid flowing through the second valve stage is also isolated from the first fluid flowing through the first valve stage.

公开(公告)号：US20180100601A1

公开(公告)日：2018-04-12

申请号：US15289170

申请日：2016-10-08

申请人： Zepto Life Technology, LLC

发明人： Gerson R. Aguirre ,  Belachew Feyssa

IPC分类号： F16K31/02 ,  B41C1/14 ,  B41F15/12 ,  B41F15/08 ,  C23C14/20 ,  C23C14/30 ,  C23C14/34 ,  F16K99/00

CPC分类号： F16K31/02 ,  A61B5/14507 ,  A61B5/14546 ,  A61B5/1468 ,  A61B2562/028 ,  A61B2562/12 ,  B01L1/00 ,  B01L3/502738 ,  B01L2300/0816 ,  B01L2400/0677 ,  B41F15/0804 ,  B41F15/12 ,  C23C14/205 ,  C23C14/30 ,  F16K99/0015 ,  F16K99/003 ,  F16K99/0042 ,  F16K2099/0073 ,  F16K2099/0074 ,  F16K2099/0084

摘要： An electrolytic membrane valve and method of its manufacture are provided. The valve includes a substrate comprising an opening and a conductive membrane impermeable to a conductive media and sealing the opening, as well as a cathode on the substrate and in communication with the membrane through the conductive media, and an anode on the substrate directly contacting the membrane. The anode is at least partially protected from electrochemical corrosion, and upon application of an electrical potential between the anode and the cathode, the membrane ruptures to allow flow of the conductive media through the opening.

公开(公告)号：US20180065097A1

公开(公告)日：2018-03-08

申请号：US15797808

申请日：2017-10-30

申请人： B. Braun Medical Inc.

发明人： Karl Konrad, JR. ,  Joel Bartholomew ,  Mike Janders ,  Linda M. Ammermann ,  Benjamin R. Lane ,  Mariano Mumpower ,  Aaron S. Pearl

IPC分类号： B01F15/02 ,  F16K99/00 ,  A61M39/22 ,  A61M39/24 ,  B01F3/08 ,  B01F5/00 ,  B01F5/04 ,  A61J3/00 ,  F16K31/04 ,  F16K11/22 ,  F16K5/04 ,  B65B3/12 ,  B01F13/10 ,  B01F13/00 ,  F16K11/085

CPC分类号： B01F15/0243 ,  A61J3/002 ,  A61J2200/70 ,  A61M39/223 ,  A61M39/24 ,  A61M2039/229 ,  B01F3/0861 ,  B01F3/0865 ,  B01F5/008 ,  B01F5/04 ,  B01F5/0403 ,  B01F13/0059 ,  B01F13/0064 ,  B01F13/1055 ,  B01F13/1066 ,  B01F15/0245 ,  B01F15/026 ,  B01F2215/0014 ,  B01F2215/0032 ,  B01F2215/0034 ,  B01F2215/0036 ,  B65B3/12 ,  F16K5/04 ,  F16K11/0856 ,  F16K11/22 ,  F16K31/041 ,  F16K99/0013 ,  F16K99/0042 ,  F16K2099/0084

摘要： An exemplary manifold for a pharmaceutical ingredient compounding device can include a housing, at least one primary intake port including a primary valve to permit or block passage of at least one primary ingredient through the manifold, and a plurality of secondary intake ports. A first channel can be in fluid communication with the at least one primary valve and include an outlet port configured to outlet the at least one primary ingredient from the manifold. A second channel can be in fluid communication with a plurality of secondary valves and include an outlet port configured to outlet at least one of a plurality of secondary ingredients from the manifold. The first channel and second channel can be in fluid isolation from each other such that the at least one primary ingredient does not mix with the plurality of secondary ingredients within the manifold.

公开(公告)号：US09709179B2

公开(公告)日：2017-07-18

申请号：US14834870

申请日：2015-08-25

申请人： Boehringer Ingelheim Vetmedica GmbH

发明人： Katja Friedrich ,  Walter Gumbrecht ,  Peter Paulicka

IPC分类号： F16K11/065 ,  F16K11/16 ,  F16K7/16 ,  F16K27/00 ,  F16K31/524 ,  F16K99/00 ,  G01N35/00 ,  B01L3/00 ,  G01N35/10

CPC分类号： F16K11/065 ,  B01L3/502738 ,  B01L2300/0636 ,  B01L2300/0816 ,  B01L2300/123 ,  B01L2400/06 ,  B01L2400/0655 ,  B01L2400/0661 ,  B01L2400/082 ,  F16K7/16 ,  F16K11/161 ,  F16K27/003 ,  F16K31/52483 ,  F16K99/0001 ,  F16K99/0015 ,  F16K99/0042 ,  F16K2099/008 ,  F16K2099/0084 ,  G01N35/1097 ,  G01N2035/00158 ,  G01N2035/00237 ,  Y10T137/0396 ,  Y10T137/86445 ,  Y10T137/86919 ,  Y10T137/87

摘要： An array of valves are arranged in n columns and m lines and which are each designed to control a fluid flow in an associated flow channel in a lab-on-a-chip system. The array includes at least two valves, every column having not more than one valve and every line having from zero to n valves. A device is used for actuating the valves. The valves are pressure-actuated. To produce the device, the flow channels are arranged in accordance with the arrangement of the valves. Which valves are actuated being changeable by movement of projections relative to array of valves so as to change which valves the projections are pressed against.

公开(公告)号：US09651166B2

公开(公告)日：2017-05-16

申请号：US14632324

申请日：2015-02-26

申请人： The Charles Stark Draper Laboratory, Inc.

发明人： Mark J. Mescher ,  Jason O. Fiering ,  Erin E. Swan

IPC分类号： F16K99/00 ,  A61M5/142 ,  G05D7/01 ,  A61M31/00 ,  A61M39/22 ,  A61M5/14 ,  A61M5/168

CPC分类号： F16K99/0015 ,  A61M5/141 ,  A61M5/14276 ,  A61M5/16809 ,  A61M5/16813 ,  A61M31/002 ,  A61M39/22 ,  A61M2039/226 ,  A61M2205/0244 ,  A61M2206/22 ,  F16K99/0001 ,  F16K99/0034 ,  F16K99/0042 ,  F16K99/0055 ,  F16K2099/0069 ,  F16K2099/0076 ,  F16K2099/008 ,  F16K2099/0088 ,  G05D7/0113 ,  G05D7/012 ,  Y10T137/0318 ,  Y10T137/0396

摘要： A microfluidic valve system includes a substrate, a valve seat a compliant membrane and a mechanically actuable displacement element. The substrate includes first and second channels embedded within it and includes a first layer of material and a second layer of material. The valve seat is in fluid communication with the first and second channels. Portions of the second layer of material form sidewalls of the second channel and the valve seat. The mechanically actuable displacement element applies a mechanical force to the compliant membrane to bring the compliant membrane into sealable contact with the valve seat, thereby closing the valve system.

公开(公告)号：US20170122298A1

公开(公告)日：2017-05-04

申请号：US15408701

申请日：2017-01-18

申请人： PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD.

发明人： Katsuhiko ASAI

IPC分类号： F03G7/06 ,  F16K99/00 ,  F04B19/00

CPC分类号： F03G7/065 ,  B01L3/50273 ,  B01L3/502738 ,  B01L2300/0864 ,  B01L2300/0887 ,  B01L2300/123 ,  B01L2300/1827 ,  B01L2400/0481 ,  B01L2400/0655 ,  B01L2400/0661 ,  F04B19/006 ,  F16K99/0005 ,  F16K99/0015 ,  F16K99/0038 ,  F16K99/0042 ,  F16K99/0044 ,  F16K2099/0084 ,  F16K2099/0094

摘要： A driving device of a micropump and a microvalve is provided. The driving device comprises a pump driver controlled by a pump controller, a valve driver controlled by a valve controller, a power supply part, a switch part. The pump driver having a first shape memory alloy wire, a micropump of the first shape memory alloy wire, a wiring part arranged in parallel to the first shape memory alloy wire, and a first selector switch that switches between a state where only the first shape memory alloy wire is energizable and a state where the wiring part is energizable. The valve driver having a plurality of second shape memory alloy wires, a plurality of microvalves of second shape memory alloy wires, and a second selector switch that brings into a state where one of the plurality of second shape memory alloy wires is energizable.

公开(公告)号：US20160310916A1

公开(公告)日：2016-10-27

申请号：US14731042

申请日：2015-06-04

申请人： B. Braun Medical Inc.

发明人： Mike Janders ,  Mariano Mumpower ,  Benjamin R. Lane

IPC分类号： B01F5/04 ,  B01F15/02

CPC分类号： B01F15/0243 ,  A61J3/002 ,  A61J2200/70 ,  A61M39/223 ,  A61M39/24 ,  A61M2039/229 ,  B01F3/0861 ,  B01F3/0865 ,  B01F5/008 ,  B01F5/04 ,  B01F5/0403 ,  B01F13/0059 ,  B01F13/0064 ,  B01F13/1055 ,  B01F13/1066 ,  B01F15/0245 ,  B01F15/026 ,  B01F2215/0014 ,  B01F2215/0032 ,  B01F2215/0034 ,  B01F2215/0036 ,  B65B3/12 ,  F16K5/04 ,  F16K11/0856 ,  F16K11/22 ,  F16K31/041 ,  F16K99/0013 ,  F16K99/0042 ,  F16K2099/0084

摘要： An exemplary pharmaceutical compounding system and device for mixing materials from at least two distinct material sources can include a transfer set and junction structure that has a junction body, a first inlet port located at a first portion of the junction body, a second inlet port located at a second portion of the junction body, and an outlet port located at a third portion of the junction body. The junction structure can be configured to mix fluid received from both the first inlet port and second inlet port and to deliver the fluid to the outlet port. The junction structure can also include attachment structure located on the junction body and configured to attach the junction structure to the housing of the compounding device at a location downstream of a pump system.

摘要翻译： 用于混合来自至少两种不同材料源的材料的示例性药物复合系统和装置可以包括转移组和连接结构，其具有连接体，位于连接体的第一部分的第一入口端口， 在连接体的第二部分处，以及位于连接体的第三部分处的出口。 接合结构可以被配置为混合从第一入口端口和第二入口端口接收的流体并将流体输送到出口端口。 连接结构还可以包括位于连接体上的连接结构，并且构造成将连接结构附接到泵系统下游位置处的复合设备的壳体。

公开(公告)号：US20160139094A1

公开(公告)日：2016-05-19

申请号：US14943962

申请日：2015-11-17

申请人： IDEX Health & Science LLC

发明人： Daniel M. HARTMANN ,  Darren LEWIS ,  Jon Nichols ,  Jim Smyth

IPC分类号： G01N30/20 ,  F16K99/00

CPC分类号： G01N30/20 ,  F16K11/074 ,  F16K99/0013 ,  F16K99/0028 ,  F16K99/0042 ,  F16K2099/0084 ,  G01N2030/027 ,  G01N2030/202

摘要： A rotary shear valve having a rotor device and a stator device both with planar faces. The stator face includes a central port located at a common rotational axis, a second port radially spaced a radius R1 from the central port, and a third port spaced at radius R2. The second and third ports are in general linear alignment with the central port. The rotor face includes a first rotor groove extending radially outward from the common rotational axis to a position at radius R2 from the central port. The rotor device is rotatably mounted to the stator device for rotation thereof about the axis, providing fluid-tight, selective relative rotation therebetween between two or more discrete rotor positions. When in a discrete first rotor position, the first rotor groove is oriented in radial alignment with, and fluidly connects, the central port and the second port with the third port.

摘要翻译： 一种具有转子装置和具有平面的定子装置的旋转剪切阀。 定子面包括位于公共旋转轴线的中心端口，与中心端口径向间隔开半径R1的第二端口和以半径R2隔开的第三端口。 第二和第三端口与中心端口通常线性对准。 转子面包括从公共旋转轴径向向外延伸到距中心端口半径R2的位置的第一转子槽。 该转子装置可旋转地安装在定子装置上，用于绕轴线旋转，从而在两个或更多个离散转子位置之间提供流体密封的选择性相对旋转。 当处于离散的第一转子位置时，第一转子槽与中心端口和第二端口与第三端口径向对准并且流体连接。