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公开(公告)号:US20240102044A1
公开(公告)日:2024-03-28
申请号:US18190954
申请日:2023-03-27
发明人: Marc van Dijk , Volker Seibert , Cornelia Anne Mundt , Arthur Andrew Hurwitz , Mark Adrian Exley , Benjamin Jacob Wolf , Daniel Leventhal , Sébastien Lalevée , Reed Masakayan
IPC分类号: C12N15/85 , A61K47/64 , A61K47/65 , C07K14/085 , C07K14/725 , C07K14/74 , C07K16/18
CPC分类号: C12N15/85 , A61K47/6425 , A61K47/65 , C07K14/085 , C07K14/7051 , C07K14/70539 , C07K16/18 , C07K2317/32 , C07K2317/34 , C07K2317/565 , C07K2319/02
摘要: Provided are TCRs (e.g., TCRs that bind to NY-ESO-1), cells and pharmaceutical compositions comprising these TCRs, nucleic acids encoding these TCRs, expression vectors and host cells for making these TCRs, and methods of treating a subject using these TCRs.
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公开(公告)号:US11759512B2
公开(公告)日:2023-09-19
申请号:US17259789
申请日:2018-11-30
申请人: MEDICAGO INC.
IPC分类号: A61K39/12 , C07K14/085 , C12N15/82
CPC分类号: A61K39/12 , C07K14/085 , C12N15/82 , C12N2770/16023 , C12N2770/16034
摘要: Nucleic acids encoding modified norovirus VP1 proteins, and VLPs comprising one or more of the modified norovirus VP1 proteins are provided. Methods for modified norovirus VP1 protein, and norovirus VLP, production in plants, portions of the plant or a plant cell, are also described.
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公开(公告)号:US20230227924A1
公开(公告)日:2023-07-20
申请号:US17784212
申请日:2020-12-23
申请人: Abbott Laboratories
发明人: Michael G. BERG , Kenn FORBERG , Todd V. MEYER , Ka-Cheung LUK
IPC分类号: C12Q1/70 , C12Q1/686 , C12N15/63 , C07K14/085
CPC分类号: C12Q1/701 , C12Q1/686 , C12N15/63 , C07K14/085 , C12N2710/00021 , C12Q2600/16
摘要: Provided herein are compositions, methods, and kits for detecting human picobirnavims (PBV). In certain embodiments, provided herein are PBV specific nucleic acid probes and primers, and methods for detecting PBV nucleic acid.
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公开(公告)号:US20160022803A1
公开(公告)日:2016-01-28
申请号:US14774729
申请日:2014-03-13
发明人: Guy BAUDOUX , Mathieu BOXUS , Brigitte COLAU , Martine MARCHAND
IPC分类号: A61K39/125 , C12N7/00 , A61K39/39 , C07K14/005 , C07K7/08
CPC分类号: A61K39/125 , A61K39/12 , A61K39/39 , A61K2039/55566 , A61K2039/6075 , A61K2039/6081 , A61K2039/64 , C07K7/08 , C07K14/005 , C07K14/085 , C12N7/00 , C12N2770/32034 , C12N2770/32334 , C12N2770/32722 , C12N2770/32734
摘要: The disclosure provides immunogenic compositions comprising human picornavirus peptides derived from structural proteins of the virus, constructs comprising the peptides, the peptides themselves and their use in the prevention of picornavirus infection and disease. Particular peptides from VP4 and VP1 are disclosed.
摘要翻译: 本公开提供包含衍生自病毒结构蛋白的人类小RNA病毒肽的免疫原性组合物,包含肽的构建体,肽本身及其在预防微小RNA病毒感染和疾病中的用途。 公开了VP4和VP1的特异性肽。
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公开(公告)号:US20130171150A1
公开(公告)日:2013-07-04
申请号:US13553461
申请日:2012-07-19
申请人: Amit Kapoor , Edward J. Dubovi , W. Ian Lipkin
发明人: Amit Kapoor , Edward J. Dubovi , W. Ian Lipkin
IPC分类号: C07K14/085 , G01N33/569 , C07K16/10 , C12Q1/70 , C12N7/00 , C12N7/04
CPC分类号: C07K14/085 , C07K14/005 , C07K16/1009 , C12N7/00 , C12N7/04 , C12N2770/32021 , C12N2770/32022 , C12Q1/701 , C12Q2600/158 , G01N33/56983 , G01N2333/085
摘要: The invention is directed to a Feline Picorna Virus, an isolated nucleic acid and amino acid sequences therefrom, and uses thereof.
摘要翻译: 本发明涉及一种猫科幻片病毒,其分离的核酸和氨基酸序列及其用途。
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