摘要:
2,5-di(p-methoxyanilino)terephthalic acid crystal types I and II are made by controlling the pH during the recovery of the oxidized product of the condensation of dimethylsuccinyl succinate with p-methoxyaniline. The resulting 2,5-di(p-methoxyanilino)-terephthalic acid can be converted into 2,9-dimethoxyquinacridone or a solid solution thereof having controlled characteristics.
摘要:
Compounds represented by formula (I), prodrugs thereof and salts thereof, and pharmaceutical compositions comprising the same as an active ingredient (wherein each symbol has the meaning as defined in the specification.). Because of having an EDG-1 agonism, the compounds represented by formula (I) are useful in preventing and/or treating peripheral arterial disease such as arteriosclerosis obliterans, thromboangiitis obliterans, Buerger's disease or diabetic neuropathy, sepsis, angiitis, nephritis, pneumonia, stroke, myocardial infarction, edematous state, atherosclerosis, varicosity such as hemorrhoid, anal fissure or fistula ani, dissecting aneurysm of the aorta, angina, DIC, pleuritis, congestive heart failure, multiple organ failure, bedsore, burn, chronic ulcerative colitis, Crohn's disease, heart transplantation, renal transplantation, dermal graft, liver transplantation, osteoporosis, pulmonary fibrosis, interstitial pneumonia, chronic hepatitis, liver cirrhosis, chronic renal failure, or glomerular sclerosis.
摘要:
The application relates to an organic electroluminescent device which contains 2,5 diaminoterephthalic acid derivatives of formula 1a as emitter substances in one or several emitter layers in a pure or doped manner. The ring A is a triple unsaturated benzene ring wherein R4′ and R8′ are equal to zero or ring A is a double unsaturated ring respectively provided with a double bond in the 1,2 position and 4,5-position, and wherein R10 is a nitrile radical —CN or a radical C(═X1)—X2R1; R11 is a nitrile radical —CN or a radical —C(═X3)—X4R5, X1 and X3 are oxygen, sulphur or imino, X2 and X4 are oxygen, sulphur or optionally substituted amino, R1 to R8, R4′ and R8′ are H, C1–C20-alkyl, aryl, heteroaryl, R4 and R8 can also be halogen, nitro, cyanogen or amino, R2 to R4, R6–R8, R4′ and R8′ can also be trifluoromethyl or pentafluorophenyl, wherein certain radicals can form a saturated or unsaturated ring. The novel devices are characterized by narrow emission bands, low driver voltages, high photometric efficiency and high thermal stability within a broad spectral range.
摘要翻译:本申请涉及一种有机电致发光器件,其以纯或掺杂的方式在一个或多个发射极层中含有2.5个式Ia的二氨基对苯二甲酸衍生物作为发射体物质。 环A是三不饱和苯环,其中R 4'和R 8'等于零或环A是分别具有双键的双不饱和环 1,2位和4,5位,其中R 10是腈基-CN或基团C(-X 1 -OR) - X 2< 1< 1> R 11是腈基-CN或-C(-X 3 O)-X 4 R 5 O X 1,X 3和X 3是氧,硫或亚氨基,X 2和X 4是氧, 硫或任选取代的氨基,R 1至R 8,R 4'和R 8'是H, C 1 -C 20烷基,芳基,杂芳基,R 4和R 8也可以是卤素,硝基,氰基或氨基,R 2至 R 4,R 6,R 8,R 4,R 8和R 8, >也可以是三氟甲基或五氟苯基,其中某些基团可以形成饱和或不饱和的环。 新颖的器件的特征在于窄的发射带,低的驱动电压,高的光度效率和宽的光谱范围内的高的热稳定性。
摘要:
The invention provides an improved process for the preparation of a compound containing a 2,4,6-triiodinated benzene ring, said process comprising reacting a 2,4,6-unsubstituted 5-amino-benzoic acid or derivative there of with an iodine halide iodinating agent in an aqueous reaction medium, characterised in that the iodinating agent is added to an aqueous medium containing the 5-amino-benzoic acid or derivative at two different temperature ranges: (A) one or more primary portions of the agent are added at a temperature in the range 40 to 70° C. and then one or more secondary portions of the agent are added at a temperature in the range 75 to 95° C. or (B) one or more primary portions of the agent are added at a temperature in the range 75 to 95° C. and then one or more secondary portions of the agent are added at a temperature of 60 to 70° C.
摘要:
A simple and efficient method for the production of stable, clear, high-potency oat extracts is disclosed. The method employs the use of differential dissociation constants and ultrafiltration to stabilise extracts, prevent hazing, and prevent the loss of functional activity as an anti-irritant and anti-oxidant. Also disclosed are compositions of oat extracts derived from whole oat grains and oatmeal. Further disclosed are compositions of oat extracts for use in cosmetic, nutraceutical, therapeutic medical and veterinary preparations.
摘要:
The invention describes a composition comprising a) an organic material which is susceptible to oxidative, thermal or light-induced degradation, and b) at least one melt additive of a compound of the formula I R1 (I) R3 X R2 wherein the general symbols are as defined in claim 1. The compounds of the formula I are useful as reducers of surface energy for organic materials, for example, for increasing the oil and water repellency of organic materials.
摘要翻译:本发明描述了一种组合物,其包含a)对氧化,热或光诱导降解敏感的有机材料,和b)式I R1(I)R3 X R2化合物的至少一种熔融添加剂,其中通用符号 如权利要求1中所定义。 式I的化合物可用作有机材料的表面能的还原剂,例如用于增加有机材料的防油和拒水性。
摘要:
The invention relates to compounds of the formula (I) in which: i and j=1; R1 is in position 3 or 4 on the phenyl ring and represents a cyano group, an alkoxy group substituted by halogen, a thioalkyl group, an alkylcarbonyl group or an alkylsulfonyl group; and R2 represents a carboxyl group, an aikoxycarbonyl group, an alkylcarbonyl group, an unsubstituted amide group or a linear or branched alkyl group substituted by a cyano, hydroxyl, cabboxyl, aikoxycarbonyl or unsubstituted amide group; and also the pharmaceutically acceptable derivatives, salts, solvates and stereoisomers thereof, including mixtures thereof in all proportions.
摘要翻译:本发明涉及式(I)化合物,其中:i和j = 1; R 1在苯环上位于3或4位,代表氰基,被卤素取代的烷氧基,硫代烷基,烷基羰基或烷基磺酰基; R 2表示羧基,烷氧基羰基,烷基羰基,未取代的酰胺基或被氰基,羟基,羧基,烷氧基羰基或未取代的酰胺基取代的直链或支链烷基; 以及其药学上可接受的衍生物,盐,溶剂化物和立体异构体,包括其各种比例的混合物。
摘要:
The present invention is a user- and eco-friendly hypervalent iodine reagent (mIBX) capable of selectively oxidizing allylic and benzylic alcohols in water and other eco-friendly solvents and having generally the following structure: Allylic and benzylic alcohols are cleanly oxidized to the corresponding carbonyl compounds in water or water-THF mixtures, or other mixtures, using a water-soluble o-iodoxybenzoic acid derivative of the present invention.
摘要:
The invention relates to an organic electroluminescent device which contains 2,5-diaminoterephthalic acid derivatives of formula 1a as emitter substances in one or several emitter layers in a pure or doped manner. The ring A is a triple unsaturated benzole ring wherein R4′ and R8′ are zero or ring A is a double unsaturated ring respectively provided with a double bond in the 1,2 position and 4,5 position, and wherein R10 is a nitrile radical —CN or a radical C(═X1)—X2R1, R11 is a nitrile radical —CN or a radical —C(═X3)—X4R5, X1 and X3 are oxygen, sulfur or imino, X2 and X4 are oxygen, sulfur or optionally substituted amino, R1-R8, R4′ and R8 are H, C1-20-alkyl, aryl, heteroaryl, R4 and R8 can be halogen, nitro, cyanogen or amino, R2-R4, R6-R8, R4′ and R8′ can be trifluoromethyl or pentafluorophenyl, and wherein certain radicals can form a saturated or unsaturated ring. The devices are characterized by narrow emission bands, low driver voltages, high photometric efficiency and high thermal stability within a broad spectral range.
摘要翻译:本发明涉及一种有机电致发光器件,其以纯或掺杂的方式包含式Ia的2,5-二氨基对苯二甲酸衍生物作为一个或多个发射极层中的发射体物质。 环A是三不饱和的苯环,其中R 4'和R 8'均为零或环A是在1,2位和4,5位分别具有双键的双不饱和环,以及 其中R 10是腈基-CN或基团C(= X 1)-X 2 R 1,R 11是腈基-CN或基团-C(= X X 4,R 5,X 1和X 3均为氧,硫或亚氨基,X 2和X 4为氧,硫或任选取代的氨基, R 1,R 8,R 4和R 8均为H,C 1-20烷基,芳基,杂芳基,R 4和R 8可以是卤素,硝基,氰基或氨基, R 2 -R 4,R 6 -R 8,R 4'和R 8'可以是三氟甲基或五氟苯基,并且其中某些基团可以形成饱和或不饱和的环。 这些器件的特征在于窄的发射带,低的驱动电压,高的光度效率和在宽光谱范围内的高的热稳定性。
摘要:
A simple and efficient method for the production of a stable, clear and high-potency oat extract, containing avenanthramide, is disclosed. The method employs the use of a differential dissociation constants and ultra filtration to stabilize extract, prevent the loss of functional activity as an anti-irritant and anti-oxidant.