Salt forms of [R-(R*,R*)]-2-(4-fluorophenyl)-beta, delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4[phenylamino) carbonyl]-1H-pyrrole-1-heptanoic acid
    7.
    发明授权
    Salt forms of [R-(R*,R*)]-2-(4-fluorophenyl)-beta, delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4[phenylamino) carbonyl]-1H-pyrrole-1-heptanoic acid 有权
    [R-(R *,R *)] -2-(4-氟苯基) - ,δ-二羟基-5-(1-甲基乙基)-3-苯基-4 [苯基氨基]羰基] 吡咯-1-庚酸

    公开(公告)号:US08822703B2

    公开(公告)日:2014-09-02

    申请号:US14016839

    申请日:2013-09-03

    申请人: Pfizer Inc.

    IPC分类号: C07D207/00

    摘要: Novel salt forms of [R—(R*,R*)]-2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid characterized by their X-ray powder diffraction pattern and solid-state NMR spectra are described, as well as methods for the preparation and pharmaceutical composition of the same, which are useful as agents for treating hyperlipidemia, hypercholesterolemia, osteoporosis, benign prostatic hyperplasia, and Alzheimer's Disease.

    摘要翻译: [R-(R *,R *)] - 2-(4-氟苯基) - ,b-的新型盐形式,δ-二羟基-5-(1-甲基乙基)-3-苯基-4 - [(苯基氨基)羰基 ] -1H-吡咯-1-庚酸,其特征在于它们的X射线粉末衍射图和固态NMR光谱,以及其制备方法和药物组合物,其可用作治疗高脂血症的药剂 ,高胆固醇血症,骨质疏松症,良性前列腺增生症和阿尔茨海默病。

    COMPLEX COMPOUND AND OPTICAL RECORDING MEDIUM CONTAINING SAME
    9.
    发明申请
    COMPLEX COMPOUND AND OPTICAL RECORDING MEDIUM CONTAINING SAME 审中-公开
    复合化合物和含有它的光学记录介质

    公开(公告)号:US20130123494A1

    公开(公告)日:2013-05-16

    申请号:US13735422

    申请日:2013-01-07

    摘要: The present invention provides a complex compound, etc., which has superior moisture- and heat-resistances, etc. and is used for an optical recording medium, including: a compound represented by Formula (I) below [in the formula, R1 represents an alkyl group which may have one or more substituents, etc., R2 represents a cyano group, etc., R3 represents an alkyl group which may have one or more substituents, etc., R4 represents a hydrogen atom, etc., R5 represents Formula (III) (in the formula, the ring A represents a heterocycle which may have one or more substituents, wherein the heterocycle is any one selected from a pyrimidine ring, a tetrazole ring, etc.)]; a metal; and any one ion selected from the group consisting of an ion formed by addition of one or more protons to an amine, an ammonium ion and a quaternary ammonium ion.

    摘要翻译: 本发明提供具有优异的耐湿性和耐热性等并用于光学记录介质的复合化合物等,其包括:由下式(I)表示的化合物[在式中,R1表示 可以具有一个或多个取代基的烷基等,R 2表示氰基等,R 3表示可具有一个或多个取代基的烷基等,R 4表示氢原子等,R 5表示 式(III)(式中,环A表示可具有一个或多个取代基的杂环,其中杂环是选自嘧啶环,四唑环等中的任一个)]。 金属 以及选自由通过向胺,铵离子和季铵离子中加入一种或多种质子形成的离子的任何一种离子。