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    Optically-induced dielectrophoresis device
    2.
    发明授权
    Optically-induced dielectrophoresis device 有权
    光诱导介电电泳装置

    公开(公告)号：US09144806B2

    公开(公告)日：2015-09-29

    申请号：US13935494

    申请日：2013-07-04

    申请人： Industrial Technology Research Institute

    发明人： Hsiu-Hsiang Chen ,  Hsin-Hsiang Lo ,  Chun-Chuan Lin ,  Chi-Shen Chang ,  Jyh-Chern Chen ,  Kuo-Tung Tiao ,  Kuo-Yao Weng

    IPC分类号： B03C5/02 ,  B03C5/00

    CPC分类号： B03C5/024 ,  B03C5/005 ,  B03C2201/26

    摘要： An optically-induced dielectrophoresis device includes a first substrate, a first conductive layer, a first patterned photoconductor layer, a first patterned layer, a second substrate, a second conductive layer, and a spacer. The first conductive layer is disposed on the first substrate. The first patterned photoconductor layer is disposed on the first conductive layer. The first patterned layer is disposed on the first conductive layer. The first patterned photoconductor layer and the first patterned layer are distributed alternately over the first conductive layer. Resistivity of the first patterned photoconductor layer is not equal to resistivity of the first patterned layer. At least one of the first substrate and the second substrate is pervious to a light. The second conductive layer is disposed on the second substrate and between the first substrate and the second substrate. The spacer connects the first substrate and the second substrate.

    摘要翻译： 光诱导介电电泳器件包括第一衬底，第一导电层，第一图案化感光体层，第一图案化层，第二衬底，第二导电层和间隔物。 第一导电层设置在第一基板上。 第一图案化感光体层设置在第一导电层上。 第一图案层设置在第一导电层上。 第一图案化感光体层和第一图案化层交替地分布在第一导电层上。 第一图案化感光体层的电阻率不等于第一图案化层的电阻率。 第一基板和第二基板中的至少一个可透过光。 第二导电层设置在第二基板上并且在第一基板和第二基板之间。 间隔件连接第一基板和第二基板。

    Electronic device for pathogen detection
    3.
    发明授权
    Electronic device for pathogen detection 有权
    用于病原体检测的电子装置

    公开(公告)号：US09120105B2

    公开(公告)日：2015-09-01

    申请号：US13664967

    申请日：2012-10-31

    申请人： Monika Weber ,  Mark A. Reed

    发明人： Monika Weber ,  Siu Lung Lo ,  Hazael Fabrizio Montanaro Ochoa ,  Christopher Daniel Yerino ,  Mark A. Reed

    IPC分类号： G01N27/447 ,  B03C5/02 ,  G01N33/487 ,  B03C5/00 ,  B01L3/00 ,  G01N27/414

    CPC分类号： B03C5/024 ,  B01L3/502753 ,  B01L2300/0874 ,  B01L2400/0406 ,  B01L2400/0424 ,  B01L2400/0487 ,  B03C5/005 ,  B03C2201/26 ,  G01N27/4145 ,  G01N33/487

    摘要： An apparatus and method for separating an analyte from a test sample, such as bacteria from blood components, based on their dielectric properties, localizing or condensing the analyte, flushing substantially all remaining waste products from the test sample, and detecting low concentrations of the analyte. Species movement is caused by a module array imparting opposing dielectrophoretic forces. The module array includes a plurality of microfluidic channels with connecting microfluidic waste channels for directing undesired material away from the analyte. An electric field is applied causing a positive dielectrophoretic force to the analyte to capture the analyte. The Clausius-Mossotti factor of the analyte is changed by flushing the analyte with a reference solution, which causes a negative dielectrophoretic force to facilitate release of the analyte. A field effect nanowire or nanoribbon sensor detects the analyte after capture.

    摘要翻译： 基于它们的介电特性，将分析物从测试样品例如细菌分离出来的装置和方法，定位或冷凝分析物，基本上冲洗来自测试样品的所有剩余废物，以及检测低浓度的分析物 。 物种移动是由赋予相反介电电泳力的模块阵列引起的。 模块阵列包括具有连接微流体废物通道的多个微流体通道，用于将不期望的材料引导离开分析物。 施加电场使得分析物具有正的介电电泳力以捕获分析物。 通过用参比溶液冲洗分析物来改变分析物的克劳修斯 - 莫索蒂（Clausius-Mossotti）因子，这引起负介电电泳力以促进分析物的释放。 场效应纳米线或纳米纤维传感器在捕获后检测分析物。

    Systems and methods to analyze materials of a suspension by means of dielectrophoresis
    4.
    发明授权
    Systems and methods to analyze materials of a suspension by means of dielectrophoresis 有权
    通过介电电泳分析悬浮液材料的系统和方法

    公开(公告)号：US08926816B2

    公开(公告)日：2015-01-06

    申请号：US13432629

    申请日：2012-03-28

    申请人： Joshua John Nordberg

    发明人： Joshua John Nordberg

    IPC分类号： B03C5/02 ,  B03C5/00

    CPC分类号： B03C5/005 ,  B03C5/024 ,  B03C2201/18 ,  B03C2201/26 ,  Y10T137/0391 ,  Y10T137/2076

    摘要： Systems and methods for trapping and moving individual particles of a target material of a suspension are disclosed. In one aspect, a system includes a tube and an electronically addressable float. The float includes one or more arrays of electrodes in which each electrode can be independently addressed to create non-uniform electric fields that trap and isolate target particles near the float. The electrodes can be dynamically operated to move the target particles to particular locations on the float for analysis and collection.

    摘要翻译： 公开了用于捕获和移动悬浮液的目标材料的各个颗粒的系统和方法。 在一个方面，系统包括管和电子寻址浮子。 浮子包括一个或多个电极阵列，其中每个电极可以独立地寻址以产生捕获和隔离浮子附近的目标颗粒的不均匀的电场。 可以动态地操作电极以将目标颗粒移动到浮子上的特定位置用于分析和收集。

    System for particle concentration and detection
    5.
    发明授权
    System for particle concentration and detection 有权
    粒子浓度和检测系统

    公开(公告)号：US08398839B1

    公开(公告)日：2013-03-19

    申请号：US12793370

    申请日：2010-06-03

    申请人： Alfredo M. Morales ,  Josh A. Whaley ,  Mark D. Zimmerman ,  Ronald F. Renzi ,  Huu M. Tran ,  Scott M. Maurer ,  William D. Munslow

    发明人： Alfredo M. Morales ,  Josh A. Whaley ,  Mark D. Zimmerman ,  Ronald F. Renzi ,  Huu M. Tran ,  Scott M. Maurer ,  William D. Munslow

    IPC分类号： B03C5/02

    CPC分类号： B03C5/005 ,  B03C5/024 ,  B03C5/026

    摘要： A new microfluidic system comprising an automated prototype insulator-based dielectrophoresis (iDEP) triggering microfluidic device for pathogen monitoring that can eventually be run outside the laboratory in a real world environment has been used to demonstrate the feasibility of automated trapping and detection of particles. The system broadly comprised an aerosol collector for collecting air-borne particles, an iDEP chip within which to temporarily trap the collected particles and a laser and fluorescence detector with which to induce a fluorescence signal and detect a change in that signal as particles are trapped within the iDEP chip.

    摘要翻译： 一种新的微流体系统已经被用于证明自动捕获和检测颗粒的可行性，该自动原型基于绝缘子的介电电泳（iDEP）触发用于病原体监测的微流体装置，其可以在实际环境中最终在实验室外运行。 该系统广泛地包括用于收集空气颗粒的气溶胶收集器，其中临时捕获收集的颗粒的iDEP芯片和用于诱导荧光信号的激光和荧光检测器，并且当颗粒被捕获在其内时，检测该信号的变化 iDEP芯片。

    Method and device for the manipulation of particles by overlapping fields of force
    6.
    发明授权
    Method and device for the manipulation of particles by overlapping fields of force 有权
    用于通过重叠的力场操纵颗粒的方法和装置

    公开(公告)号：US08268151B2

    公开(公告)日：2012-09-18

    申请号：US12376761

    申请日：2007-08-07

    申请人： Giovanni Medoro ,  Nicolo Manaresi

    发明人： Giovanni Medoro ,  Nicolo Manaresi

    IPC分类号： G01N27/447

    CPC分类号： B03C5/026 ,  B03C5/005 ,  B03C5/024

    摘要： Methods and relative devices are illustrated for generating time-variable electric fields suitable for determining the creation of closed dielectrophoretic cages able to trap inside even single particles without the cages being necessarily positioned at relative minimum points of the electric field.

    摘要翻译： 示出了用于产生时间变化电场的方法和相关装置，用于确定能够捕获甚至单个颗粒内的封闭介电电泳笼的产生，而不需要将笼定位在电场的相对最小点处。

    Arbitrary and simultaneous control of multiple objects in micro-fluidic systems
    7.
    发明授权
    Arbitrary and simultaneous control of multiple objects in micro-fluidic systems 有权
    任意和同时控制微流体系统中的多个物体

    公开(公告)号：US08110083B1

    公开(公告)日：2012-02-07

    申请号：US12651742

    申请日：2010-01-04

    申请人： Benjamin Shapiro ,  Satej V. Chaudhary ,  Michael D. Armani ,  Roland Probst

    发明人： Benjamin Shapiro ,  Satej V. Chaudhary ,  Michael D. Armani ,  Roland Probst

    IPC分类号： C25B9/00

    CPC分类号： B03C5/024 ,  G01N15/1459 ,  G01N15/1463 ,  G01N2015/149

    摘要： In a microfluidic device, respective motion of a plurality of objects along corresponding trajectories is achieved by determining a force field, such as an underlying fluid flow which, when applied to the plurality of object, moves each object along its corresponding trajectory. The force field is a linear superposition of a subset of all force fields supported by the physical characteristics of the microfluidic device. Once the fields have been ascertained, a plurality of actuation signals corresponding to the fields is applied to actuators installed on the microfluidic device to cause the force on each object. By implementing a feedback structure, corrections for positional errors may be made by computing a corrective force for each object and adjusting the actuation signals appropriately thereto.

    摘要翻译： 在微流体装置中，通过确定力场，例如当应用于多个物体时，沿着其对应的轨迹移动每个物体的下面的流体流动来实现沿对应轨迹的多个物体的相应运动。 力场是由微流体装置的物理特性支持的所有力场的子集的线性叠加。 一旦已经确定了这些场，则将与场相对应的多个致动信号施加到安装在微流体装置上的致动器，以对每个物体施加力。 通过实施反馈结构，可以通过计算每个物体的校正力并适当调整致动信号来进行位置误差校正。