公开(公告)号：US4663163A

公开(公告)日：1987-05-05

申请号：US576448

申请日：1984-02-02

Applicant: Kenneth C. Hou ,  Tung-Ping D. Liao

Inventor： Kenneth C. Hou ,  Tung-Ping D. Liao

IPC: B01J20/28 ,  B01J20/32 ,  B01J39/22 ,  B01J41/16 ,  B01J47/12 ,  C08F251/00 ,  C08G81/02 ,  G01N30/38 ,  G01N30/60 ,  A61K35/16 ,  B01J20/00

CPC classification number: B01J20/28028 ,  B01J20/28033 ,  B01J20/28052 ,  B01J20/3212 ,  B01J20/3278 ,  B01J20/328 ,  B01J20/3282 ,  B01J39/22 ,  B01J39/26 ,  B01J41/16 ,  B01J41/20 ,  B01J47/123 ,  C08F251/00 ,  C08G81/02 ,  G01N2030/386 ,  G01N30/6091

Abstract: A modified polysaccharide material which comprises: (1) polysaccharide covalently bonded to a synthetic polymer; (2) the synthetic polymer being made from (a) a polymerizable compound which is capable of being covalently coupled directly or indirectly to said polysaccharide, and (b) one or more polymerizable compounds containing (i) an ionizable chemcial group, (ii) a chemical group capable of transformation to an ionizable chemical group, (iii) a chemical group capable of causing the covalent coupling of the compound (b) to an affinity ligand or a biologically active molecule or (iv) a hydrophobic compound.

Abstract translation: 一种改性多糖材料，其包括：（1）共价键合到合成聚合物上的多糖; （2）合成聚合物由（a）能够直接或间接地共价连接到所述多糖的可聚合化合物制成，和（b）一种或多种可聚合化合物，其包含（i）可电离化学基团，（ii） 能够转化为可电离化学基团的化学基团，（iii）能够使化合物（b）与亲和配体或生物活性分子共价偶联的化学基团，或（iv）疏水性化合物。

公开(公告)号：US3651043A

公开(公告)日：1972-03-21

申请号：US3651043D

申请日：1969-04-01

Applicant: INST DE BIOCHIMIE

Inventor： SCHELL HORST D ,  GHETIE VICTOR F

IPC: B01D15/04 ,  B01J39/22 ,  B01J41/16 ,  C08B37/00 ,  C08G65/26 ,  C08G73/02 ,  C07C47/18

CPC classification number: C08G65/2606 ,  B01J39/22 ,  B01J41/16 ,  C08B37/0039 ,  C08G73/022

Abstract: THE PRESENT INVENTION DEALS WITH THE SYNTHESIS OF NEW BASIC ION EXCHANGERS OF MEDIUM STRENGTH DERIVED FROM AGAROSE. THE PROCEDURE FOR OBTAINING THESE DERIVATIVES, ACCORDING TO THE INVENTION, CONSISTS INREACTING SIMPLE OR GLYCERIC BRIDGE CROSS-LINKED AGAROSE WITH AN EQUIMOLECULAR MIXTURE OF EPICHLOROHYDRIN AND TRIETHANOLAMINE.

公开(公告)号：US3395070A

公开(公告)日：1968-07-30

申请号：US41580664

申请日：1964-12-03

Applicant: TEE PAK INC

Inventor： ADAMS JAMES W ,  HOFTIEZER HENRY W

IPC: B01J41/16 ,  C08F8/12 ,  C08F251/02

CPC classification number: D21H5/143 ,  B01J41/16 ,  C08F8/12 ,  C08F8/32 ,  C08F251/02 ,  D21H11/06 ,  D21H11/20 ,  C08F2220/1808 ,  C08F220/44 ,  C08F218/08 ,  C08F220/34 ,  C08F2220/1825 ,  C08F220/56 ,  C08F2220/1858 ,  C08F212/08

公开(公告)号：US3311608A

公开(公告)日：1967-03-28

申请号：US25785963

申请日：1963-02-12

Applicant: MURPHY JOHN P

Inventor： MURPHY JOHN P

IPC: B01J41/16

CPC classification number: B01J41/16 ,  Y10S521/905

公开(公告)号：US20230158483A1

公开(公告)日：2023-05-25

申请号：US17920135

申请日：2021-04-23

Applicant: TOYOBO CO., LTD.

Inventor： Ayano Higaki ,  Hirofumi Hakuba

IPC: B01J41/16 ,  B01J41/04 ,  C08J5/22 ,  B01D69/02 ,  B01J47/014

CPC classification number: B01J41/16 ,  B01J41/04 ,  C08J5/2212 ,  B01D69/02 ,  B01J47/014 ,  B01D2325/02833 ,  B01D2325/02834 ,  B01D2325/022 ,  B01D2325/04 ,  B01D2325/16 ,  B01D2325/42 ,  C08J2301/08

Abstract: An object of the present invention is to provide an ion-exchange membrane for simply and inexpensively separating and purifying exosomes present in a biological sample such as serum. The invention relates to a cellulose-based ion-exchange membrane containing a cellulose-based polymer having at least one hydroxyl group or acetyl group at the 2-, 3-, or 6-position being replaced with a positively charged compound. The invention also relates to a method for purifying exosomes, including subjecting a sample containing exosomes to membrane permeation by using the cellulose-based ion-exchange membrane to allow for adsorption of the exosomes, bringing the membrane into contact with a washing liquid to remove impurities, and bringing the membrane into contact with an eluent to allow for desorption of the exosomes.

公开(公告)号：US20170332627A1

公开(公告)日：2017-11-23

申请号：US15474090

申请日：2017-03-30

Applicant: CROP ENHANCEMENT, INC.

Inventor： K. Suzanne Rawden ,  Sandra Rifai ,  Gangadhar Jogikalmath ,  Andrea Schneider ,  Jonathan Flores ,  David S. Soane

IPC: A01N25/22 ,  A01N25/10 ,  A01N25/26 ,  B01J45/00

CPC classification number: A01N25/22 ,  A01N25/10 ,  A01N25/26 ,  B01J39/20 ,  B01J39/22 ,  B01J41/14 ,  B01J41/16 ,  B01J45/00 ,  C05F11/10 ,  C05G3/0047 ,  C05G3/0052

Abstract: The invention encompasses resinate formulations comprising an agricultural active ingredient and an ion exchange resin, wherein the agricultural active ingredient is imbibed upon the ion exchange resin; and methods of treating an agricultural surface. The invention also encompasses methods of manufacturing an agricultural formulation comprising a resinate, comprising: providing an agricultural active ingredient and an ion exchange resin; and mixing the agricultural active ingredient and the ion exchange resin to imbibe the agricultural active ingredient upon the ion exchange resin, thereby forming the resinate.

公开(公告)号：US09587154B2

公开(公告)日：2017-03-07

申请号：US11221595

申请日：2005-09-08

Applicant: Bo Yang ,  Filipe J. Marinho ,  Peter M. Woyciesjes ,  Aleksei V. Gershun

Inventor： Bo Yang ,  Filipe J. Marinho ,  Peter M. Woyciesjes ,  Aleksei V. Gershun

IPC: H01M8/04 ,  C09K5/10 ,  B01J47/00 ,  C08J5/20 ,  F01P11/06

CPC classification number: C09K5/10 ,  B01J41/16 ,  B01J47/016 ,  C08J5/20 ,  C23F11/00 ,  C23F11/149 ,  F01P2011/068 ,  H01M8/04029 ,  Y02E60/50 ,  Y02P70/56

Abstract: Disclosed is a pre-treated ion exchange resin comprising at least 15% by total number of exchangeable groups comprising at least one of an ion, or a Lewis acid, or a Lewis base resulting from a heat transfer fluid component having a pKa or pKb of greater than 5 in an aqueous solution at 25° C., based on the total number of exchangeable groups. In one embodiment, the heat transfer fluid component is at least one of a colorant, a corrosion inhibitor, an antifoaming agent, a bitterant, a dispersant, or a combination thereof. In one embodiment, the heat transfer fluid component comprises a heat transfer fluid corrosion inhibitor. Also disclosed are heat transfer systems, assemblies, fuel cell systems and methods of maintaining a conductivity of less than 200 μS/cm in a heat transfer fluid that employ the disclosed pre-treated ion exchange resins.

Abstract translation: 公开了一种预处理的离子交换树脂，其包含至少15％的总交换基团数，该可交换基团包含由具有pKa或pKb的传热流体组分产生的离子或路易斯酸或路易斯碱中的至少一种 在25℃的水溶液中大于5，基于可交换基团的总数。 在一个实施方案中，传热流体组分是着色剂，腐蚀抑制剂，消泡剂，苦味剂，分散剂或其组合中的至少一种。 在一个实施方案中，传热流体组分包括传热流体腐蚀抑制剂。 还公开了在采用公开的预处理的离子交换树脂的传热流体中的传热系统，组件，燃料电池系统和维持小于200μS/ cm的导电率的方法。

公开(公告)号：US5354472A

公开(公告)日：1994-10-11

申请号：US981912

申请日：1992-11-23

Applicant: Marc Voorhees ,  Ben F. Brian, III ,  Lloyd Forrestal

Inventor： Marc Voorhees ,  Ben F. Brian, III ,  Lloyd Forrestal

IPC: G01N30/00 ,  A61M1/36 ,  B01D15/08 ,  B01J20/26 ,  B01J20/28 ,  B01J20/281 ,  B01J20/285 ,  B01J20/32 ,  B01J41/12 ,  B01J41/16 ,  C08J5/22 ,  D04H1/44 ,  D04H1/46 ,  G01N30/88 ,  C02J5/20

CPC classification number: C08J5/2275 ,  A61M1/3675 ,  B01J41/16 ,  B01J41/20 ,  C08J5/2212 ,  D04H1/44 ,  D04H1/46 ,  C08J2301/08 ,  C08J2435/02

Abstract: A novel biocompatible anion exchange membrane is prepared by reacting the hydroxyl groups of a chromatographic support material with a polyester-cellulose solution containing glycidyl trimethyl ammonium chloride and bis glycidyl polyethylene oxide.

Abstract translation: 通过使色谱载体材料的羟基与含有缩水甘油基三甲基氯化铵和双缩水甘油基聚环氧乙烷的聚酯 - 纤维素溶液反应来制备新的生物相容性阴离子交换膜。

公开(公告)号：US07018665B2

公开(公告)日：2006-03-28

申请号：US10149339

申请日：2000-12-08

Applicant: John Stephen Ayers ,  David Francis Elgar ,  Kay Patricia Palmano ,  Mark Pritchard ,  Ganugapati Bijaya Bhaskar

Inventor： John Stephen Ayers ,  David Francis Elgar ,  Kay Patricia Palmano ,  Mark Pritchard ,  Ganugapati Bijaya Bhaskar

IPC: A23C21/00

CPC classification number: B01J41/16 ,  A23C9/1465 ,  A23J1/205 ,  A23V2002/00 ,  A23V2250/54242 ,  A23V2250/5434 ,  A23V2300/30

Abstract: The present invention relates to new processes useful for separating whey proteins from whey protein-containing solutions using a novel anion exchanger which comprises a water insoluble, hydrophilic, water swellable, hydroxy (C2–C4) alkylated and cross-linked regenerated cellulose, derivatized with quaternary amino (QA) groups where the level of substitution of the QA groups is 1.4 milli-equivalents per dry gram of anion exchanger (meq/g) or greater.

Abstract translation: 本发明涉及用于从含乳清蛋白的溶液中分离乳清蛋白的新方法，该新型阴离子交换剂包含水不溶性，亲水性，水可溶胀的羟基（C 2 -C 2 - 4QA）烷基化和交联的再生纤维素，其季铵基（QA）基团衍生化，其中QA基团的取代水平为1.4毫当量/干燥阴离子交换剂（meq / g）或更大。

公开(公告)号：US20060049167A1

公开(公告)日：2006-03-09

申请号：US11221595

申请日：2005-09-08

Applicant: Bo Yang ,  Filipe Marinho ,  Peter Woyciesjes ,  Aleksei Gershun

Inventor： Bo Yang ,  Filipe Marinho ,  Peter Woyciesjes ,  Aleksei Gershun

IPC: F27B9/06 ,  F27D11/00

CPC classification number: C09K5/10 ,  B01J41/16 ,  B01J47/016 ,  C08J5/20 ,  C23F11/00 ,  C23F11/149 ,  F01P2011/068 ,  H01M8/04029 ,  Y02E60/50 ,  Y02P70/56

Abstract: Disclosed is a pre-treated ion exchange resin comprising at least 15% by total number of exchangeable groups comprising at least one of an ion, or a Lewis acid, or a Lewis base resulting from a heat transfer fluid component having a pKa or pKb of greater than 5 in an aqueous solution at 25° C., based on the total number of exchangeable groups. In one embodiment, the heat transfer fluid component is at least one of a colorant, a corrosion inhibitor, an antifoaming agent, a bitterant, a dispersant, or a combination thereof. In one embodiment, the heat transfer fluid component comprises a heat transfer fluid corrosion inhibitor. Also disclosed are heat transfer systems, assemblies, fuel cell systems and methods of maintaining a conductivity of less than 200 μS/cm in a heat transfer fluid that employ the disclosed pre-treated ion exchange resins.

Abstract translation: 公开了一种预处理的离子交换树脂，其包含至少15％的可交换基团数量，所述可交换基团包含离子或路易斯酸或路易斯碱中的至少一种，所述交联基团由具有pK 在25℃的水溶液中，基于可交换基团的总数，大于5的p 或pK b b 大于5。 在一个实施方案中，传热流体组分是着色剂，腐蚀抑制剂，消泡剂，苦味剂，分散剂或其组合中的至少一种。 在一个实施方案中，传热流体组分包括传热流体腐蚀抑制剂。 还公开了在采用公开的预处理的离子交换树脂的传热流体中的传热系统，组件，燃料电池系统和保持小于200μS/ cm的电导率的方法。