公开(公告)号：US12023398B2

公开(公告)日：2024-07-02

申请号：US17264200

申请日：2019-07-01

申请人： RICOH COMPANY, LTD.

发明人： Tatsuki Yamaguchi ,  Masahide Kobayashi ,  Mitsunobu Morita ,  Takashi Okada ,  Soh Noguchi ,  Takenori Suenaga

IPC分类号： A61K8/42 ,  A45D29/00 ,  A45D31/00 ,  A61K8/37 ,  A61K8/81 ,  A61Q3/00 ,  A61Q3/02 ,  C08F2/48 ,  C08F2/50 ,  C08F20/56 ,  C08F220/58 ,  C09D4/00 ,  G03C1/73 ,  G03C1/74

CPC分类号： A61K8/42 ,  A45D31/00 ,  A61K8/375 ,  A61K8/8141 ,  A61K8/8158 ,  A61K8/8194 ,  A61Q3/00 ,  A61Q3/02 ,  C08F2/48 ,  C08F2/50 ,  C08F20/56 ,  C08F220/58 ,  C09D4/00 ,  G03C1/73 ,  G03C1/74 ,  A45D2029/005 ,  A45D2200/205 ,  A61K2800/81 ,  A61K2800/87 ,  A61K2800/95

摘要： Provided is a composition including: an acrylamide compound (A1) having a molecular weight of 150 or greater but 250 or less; and a multifunctional polymerizable compound (A2), wherein a content of the multifunctional polymerizable compound (A2) is 15% by mass or greater but 35% by mass or less.

公开(公告)号：US11938117B2

公开(公告)日：2024-03-26

申请号：US15693223

申请日：2017-08-31

申请人： NUTRITION 21, LLC

发明人： Deanna J. Nelson ,  James R. Komorowski

IPC分类号： A61K31/4188 ,  A61G3/00 ,  A61K8/19 ,  A61K8/67 ,  A61K9/00 ,  A61K9/20 ,  A61K9/28 ,  A61Q3/00 ,  A61Q5/00 ,  A61Q7/00

CPC分类号： A61K31/4188 ,  A61K8/19 ,  A61K8/673 ,  A61K9/0053 ,  A61K9/2086 ,  A61K9/28 ,  A61K9/2806 ,  A61Q3/00 ,  A61Q5/002 ,  A61Q7/00 ,  A61K2800/58

摘要： The present application relates to magnesium biotinate compositions and methods of use. The methods and compositions disclosed herein are particularly useful for providing bioavailable biotin to mammals and treating or preventing symptoms of biotin deficiency.

公开(公告)号：US11931342B2

公开(公告)日：2024-03-19

申请号：US16855966

申请日：2020-04-22

申请人： NUTRITION 21, LLC

发明人： Deanna J. Nelson ,  James R. Komorowski

IPC分类号： A61K31/4188 ,  A61G3/00 ,  A61K8/19 ,  A61K8/67 ,  A61K9/00 ,  A61K9/20 ,  A61K9/28 ,  A61Q3/00 ,  A61Q5/00 ,  A61Q7/00

CPC分类号： A61K31/4188 ,  A61K8/19 ,  A61K8/673 ,  A61K9/0053 ,  A61K9/2086 ,  A61K9/28 ,  A61K9/2806 ,  A61Q3/00 ,  A61Q5/002 ,  A61Q7/00 ,  A61K2800/58

摘要： The present application relates to magnesium biotinate compositions and methods of use. The methods and compositions disclosed herein are particularly useful for providing bioavailable biotin to mammals and treating or preventing symptoms of biotin deficiency.

公开(公告)号：US11708392B2

公开(公告)日：2023-07-25

申请号：US17012724

申请日：2020-09-04

申请人： BIONIZ, LLC

发明人： Yutaka Tagaya ,  Nazli Azimi

IPC分类号： C07K7/08 ,  C07K7/06 ,  C07K14/52 ,  C07K14/54 ,  A61K8/64 ,  A61K38/20 ,  A61K38/10 ,  A61K38/00 ,  A61Q3/00 ,  A61Q7/00 ,  A61Q19/00 ,  A61Q19/08 ,  A61P1/04 ,  A61P3/10 ,  A61P5/14 ,  A61P11/00 ,  A61P11/02 ,  A61P11/06 ,  A61P11/08 ,  A61P17/00 ,  A61P17/02 ,  A61P17/06 ,  A61P17/10 ,  A61P17/14 ,  A61P19/02 ,  A61P25/00 ,  A61P25/02 ,  A61P25/28 ,  A61P27/02 ,  A61P27/16 ,  A61P29/00 ,  A61P35/02 ,  A61P37/02 ,  A61P37/06 ,  A61P37/08 ,  A61P43/00 ,  A61K47/64

CPC分类号： C07K7/08 ,  A61K8/64 ,  A61K38/20 ,  A61K47/642 ,  A61K47/643 ,  A61Q3/00 ,  A61Q7/00 ,  A61Q19/00 ,  A61Q19/004 ,  A61Q19/08 ,  C07K7/06 ,  C07K14/52 ,  C07K14/54 ,  A61K38/00 ,  A61K38/10

摘要： Methods and compositions related to the selective, specific disruption of multiple ligand-receptor signaling interactions, such as ligand-receptor interactions implicated in disease, are disclosed. These interactions may involve multiple cytokines in a single receptor family or multiple ligand receptor interactions from at least two distinct ligand-receptor families. The compositions may comprise polypeptides having composite sequences that comprise sequence fragments of two or more ligand binding sites. The methods and compositions may involve sequence fragments of two or more ligand binding sites that are arranged to conserve the secondary structure of each of the ligands from which the sequence fragments were taken.

公开(公告)号：US20180071264A1

公开(公告)日：2018-03-15

申请号：US15693223

申请日：2017-08-31

申请人： JDS Therapeutics, LLC

发明人： Deanna J. Nelson ,  James R. Komorowski

IPC分类号： A61K31/4188 ,  A61K9/28 ,  A61K9/00 ,  A61Q7/00 ,  A61K8/67 ,  A61Q5/00 ,  A61Q3/00

CPC分类号： A61K31/4188 ,  A61K8/19 ,  A61K8/673 ,  A61K9/0053 ,  A61K9/2086 ,  A61K9/28 ,  A61K9/2806 ,  A61K2800/58 ,  A61Q3/00 ,  A61Q5/002 ,  A61Q7/00

摘要： The present application relates to magnesium biotinate compositions and methods of use. The methods and compositions disclosed herein are particularly useful for providing bioavailable biotin to mammals and treating or preventing symptoms of biotin deficiency.

公开(公告)号：US09901535B2

公开(公告)日：2018-02-27

申请号：US14432438

申请日：2013-09-27

申请人： NUTRICOS TECHNOLOGIES

发明人： Nathalie Piccardi ,  Yann Mahe ,  Carole Bru

IPC分类号： A61K8/97 ,  A61K8/27 ,  A61K8/46 ,  A61Q3/00 ,  A61K8/67 ,  A23L33/105 ,  A23L33/15 ,  A23L33/16 ,  A23L33/175

CPC分类号： A61K8/97 ,  A23L33/105 ,  A23L33/15 ,  A23L33/16 ,  A23L33/175 ,  A23V2002/00 ,  A61K8/27 ,  A61K8/466 ,  A61K8/673 ,  A61K8/676 ,  A61K2800/88 ,  A61K2800/884 ,  A61K2800/92 ,  A61Q3/00

摘要： The invention relates to the oral cosmetic use of a combination of active agents comprising at least taurine, a derivative thereof and/or an acceptable salt thereof and at least one grape extract, as cosmetic active agents for improving the quality of the nails. More particularly, the present invention relates to the oral cosmetic use of such a combination for improving the solidity of the nails and for reducing and/or preventing their splitting.

公开(公告)号：US20170296674A1

公开(公告)日：2017-10-19

申请号：US15343371

申请日：2016-11-04

申请人： Alex Battaglia ,  Eva Beim

发明人： Alex Battaglia ,  Eva Beim

IPC分类号： A61K47/46 ,  A61Q17/00 ,  A61Q3/00 ,  A61K31/56 ,  A61K31/5386 ,  A61K31/465 ,  A61K31/21 ,  A61K9/70 ,  A61K8/92 ,  A61Q19/00 ,  A61K8/49

CPC分类号： A61K47/46 ,  A61K8/494 ,  A61K8/922 ,  A61K9/7015 ,  A61K31/21 ,  A61K31/465 ,  A61K31/5386 ,  A61K31/56 ,  A61Q3/00 ,  A61Q17/005 ,  A61Q19/00

摘要： Described are pharmacological compositions comprising a gum resin; a pharmacologically active agent and a topically acceptable volatile solvent for the gum resin and active agent. Also described are methods for the transdermal or transmucosal delivery of a pharmacologically active agent using such compositions.

公开(公告)号：US09770400B2

公开(公告)日：2017-09-26

申请号：US13989905

申请日：2011-11-30

申请人： Anthony Courtois ,  Bertrand Thollas ,  Raquel Delgado Gonzalez ,  Juan Cebrian Puche ,  Albert Soley Astals

发明人： Anthony Courtois ,  Bertrand Thollas ,  Raquel Delgado Gonzalez ,  Juan Cebrian Puche ,  Albert Soley Astals

IPC分类号： C12P1/04 ,  C12N1/00 ,  A61K8/73 ,  A61K8/06 ,  A61K8/14 ,  A61K8/81 ,  A61K8/99 ,  A61K9/00 ,  A61K47/36 ,  A61Q19/00 ,  A61Q19/08 ,  A61Q3/00 ,  A61Q5/00 ,  A61K9/107 ,  A61K9/127

CPC分类号： A61K8/73 ,  A61K8/068 ,  A61K8/14 ,  A61K8/735 ,  A61K8/8182 ,  A61K8/99 ,  A61K9/0014 ,  A61K9/1075 ,  A61K9/127 ,  A61K47/36 ,  A61K2800/21 ,  A61K2800/56 ,  A61K2800/85 ,  A61K2800/92 ,  A61Q3/00 ,  A61Q5/00 ,  A61Q19/007 ,  A61Q19/08

摘要： A method includes administering a cosmetically or dermopharmaceutically effective quantity of exopolysaccharide of a bacterial strain isolated from Pseudoalteromonas sp. with deposit number CNCM I-4150 to at least one of skin, mucous membranes, hair and nails for the treatment and/or care of the skin, mucous membranes, hair and/or nails, and cosmetic and/or dermopharmaceutical compositions including the exopolysaccharide. In particular, the method and composition are suited to treatment of the aging of skin and for the treatment and/or care of disorders, conditions and/or diseases which are a result of a lack or decrease in hydration.

公开(公告)号：US09682025B2

公开(公告)日：2017-06-20

申请号：US14890071

申请日：2014-05-06

申请人： NUTRICOS TECHNOLOGIES

发明人： Yann Mahe ,  Carole Bru ,  Nathalie Piccardi ,  Audrey Gueniche

IPC分类号： A61K8/36 ,  A61K8/27 ,  A61K8/31 ,  A61K8/44 ,  A61K8/46 ,  A61Q3/00 ,  A61K8/92 ,  A61K8/97 ,  A61K8/43 ,  A61K8/58 ,  A61K8/67 ,  A61Q3/02 ,  A23L33/12

CPC分类号： A61K8/361 ,  A23L33/12 ,  A23V2002/00 ,  A61K8/27 ,  A61K8/31 ,  A61K8/43 ,  A61K8/44 ,  A61K8/447 ,  A61K8/466 ,  A61K8/58 ,  A61K8/67 ,  A61K8/678 ,  A61K8/922 ,  A61K8/97 ,  A61K2800/92 ,  A61Q3/00 ,  A61Q3/02

摘要： The invention relates to the cosmetic use, by oral administration, of a combination of active agents including at least petroselinic acid and at least one active agent selected from among taurine, arginine, cysteine, zinc, a salt thereof, and lycopene, for improving the quality of nails, specifically the microvascularization of the nails, in particular in pre-hypertensive individuals.

公开(公告)号：US09649512B2

公开(公告)日：2017-05-16

申请号：US13318596

申请日：2010-05-04

申请人： Graham Matheson

发明人： Graham Matheson

IPC分类号： A61Q3/00 ,  A61K8/97 ,  A61K9/00 ,  A61K36/185 ,  A61K36/48 ,  A61K36/889 ,  A61L15/40 ,  A61L26/00 ,  A61Q7/00 ,  A61Q19/08 ,  A61Q5/00 ,  A61Q19/00

CPC分类号： A61Q3/00 ,  A61K8/97 ,  A61K9/0014 ,  A61K36/185 ,  A61K36/48 ,  A61K36/889 ,  A61L15/40 ,  A61L26/0057 ,  A61Q5/00 ,  A61Q7/00 ,  A61Q19/00 ,  A61Q19/08

摘要： Biologically active extracts of one or more Vigna marina (Burm.) Merr., Cocos nucifera L., or Terminalia catappa L. and compositions one or more of the extracts are described. The invention also provides therapeutic and cosmetic uses of the extracts and compositions, in particular for promoting wound healing and for the treatment of skin disorders.