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公开(公告)号：US20230346865A1
公开(公告)日：2023-11-02
申请号：US18219412
申请日：2023-07-07
CPC分类号： A61K36/31 , A23L2/00 , A61K9/0053 , A61K9/0095 , A61K9/1664 , A61K9/00
摘要： The present application is directed to composition comprising various maca extracts and the use of such compositions for treating certain diseases, disorders, and conditions.
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2.发明授权公开(公告)号：US11801224B2
公开(公告)日：2023-10-31
申请号：US17686827
申请日：2022-03-04
发明人： James R. Komorowski
CPC分类号： A61K9/209 , A23L33/15 , A61K9/00 , A61K9/0053 , A61K31/155 , A61K33/24 , A61K45/06 , A23V2002/00 , Y02A50/30
摘要： Compositions and methods for combination therapy are provided. The compositions comprise a multiple unit dosage form having both a therapeutic agent and a nutritional supplement. The combination therapy is useful for restoring a nutrient depletion associated with a particular disease state. Additionally, the combination therapy can prevent or attenuate the depletion of a nutrient caused, in whole or in part, by the co-administrated therapeutic drug. Methods of manufacturing the formulations are likewise described.
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公开(公告)号：US20230158105A1
公开(公告)日：2023-05-25
申请号：US17953307
申请日：2022-09-26
发明人： James R. Komorowski
IPC分类号： A61K38/16 , C12P21/06 , A61P39/06 , A61P31/04 , A61K33/04 , A61K33/30 , A61P31/12 , A61K31/706 , A23L33/00 , A23L33/18 , A23L33/16
CPC分类号： A61K38/164 , C12Y304/21062 , C12P21/06 , A61P39/06 , A61P31/04 , A61K33/04 , A61K33/30 , A61P31/12 , A61K31/706 , A23L33/40 , A23L33/18 , A23L33/16
摘要： Processes for producing oligo-chromopeptides from phycocyanin are disclosed. Additionally, compositions comprising oligo-chromopeptides and combination of oligo-chromopeptides with at least one of the compounds namely, nicotinamide riboside, zinc, selenium, or a combination thereof are disclosed. Uses and methods of treating, preventing, or ameliorating age-related somatic disease, bacterial and/or viral infections/diseases, and diseases associated with oxidative stress, or symptoms associated with any of the foregoing are also disclosed.
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4.发明授权公开(公告)号：US11241388B2
公开(公告)日：2022-02-08
申请号：US16524591
申请日：2019-07-29
发明人： James R. Komorowski
IPC分类号： A61K9/24 , A61K9/00 , A61K31/155 , A61K45/06 , A23L33/15
摘要： Compositions and methods for combination therapy are provided. The compositions comprise a multiple unit dosage form having both a therapeutic agent and a nutritional supplement. The combination therapy is useful for restoring a nutrient depletion associated with a particular disease state. Additionally, the combination therapy can prevent or attenuate the depletion of a nutrient caused, in whole or in part, by the co-administrated therapeutic drug. Methods of manufacturing the formulations are likewise described.
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公开(公告)号：US20210308177A1
公开(公告)日：2021-10-07
申请号：US17244442
申请日：2021-04-29
IPC分类号： A61K33/06 , A61K31/191 , A23L33/16 , A61K9/00 , A61P25/20
摘要： Compounds, compositions and methods of making and using for enhancing the quality and benefit of sleep and/or wakefulness in a subject in need thereof.
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公开(公告)号：US20210213087A1
公开(公告)日：2021-07-15
申请号：US17214314
申请日：2021-03-26
摘要： The present application is directed to composition comprising various maca extracts and the use of such compositions for treating certain diseases, disorders, and conditions.
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公开(公告)号：US20180110818A1
公开(公告)日：2018-04-26
申请号：US15785170
申请日：2017-10-16
IPC分类号： A61K36/31
CPC分类号： A61K36/31 , A23L2/00 , A61K9/0053 , A61K9/0095 , A61K9/1664
摘要： The present application is directed to composition comprising various maca extracts and the use of such compositions for treating certain diseases, disorders, and conditions.
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公开(公告)号：US20160375035A1
公开(公告)日：2016-12-29
申请号：US15188231
申请日：2016-06-21
发明人： James R Komorowski
IPC分类号： A61K31/555 , A23L33/10
CPC分类号： A61K31/555 , A23K20/142 , A23L33/10 , A23L33/165 , A23V2002/00 , A61K31/28 , A61K31/4172 , A61K45/06 , A61K2300/00 , A23V2200/328 , A23V2250/15
摘要： This present disclosure generally relates to the discovery that chromium histidinate (CrHis) and chromium picolinate (CrPic) can exist as complexes in multiple forms. More particularly, the present disclosure is directed to the surprising discovery that particular forms/isomers (or combinations of forms/isomers) of such chromium complexes have greater activity than others.
摘要翻译： 本公开内容通常涉及组氨酸铬（CrHis）和吡啶甲酸铬（CrPic）可以作为复合物以多种形式存在的发现。 更具体地，本公开涉及令人惊奇的发现，即这种铬络合物的特定形式/异构体（或形式/异构体的组合）具有比其它复合物更大的活性。
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9.发明授权公开(公告)号：US09421170B2
公开(公告)日：2016-08-23
申请号：US14642243
申请日：2015-03-09
发明人： James R. Komorowski
IPC分类号： A61K9/00 , A61K9/24 , A61K45/06 , A61K31/155
CPC分类号： A61K9/209 , A23L33/15 , A23V2002/00 , A61K9/00 , A61K9/0053 , A61K31/155 , A61K45/06 , Y02A50/422
摘要： Compositions and methods for combination therapy are provided. The compositions comprise a multiple unit dosage form having both a therapeutic agent and a nutritional supplement. The combination therapy is useful for restoring a nutrient depletion associated with a particular disease state. Additionally, the combination therapy can prevent or attenuate the depletion of a nutrient caused, in whole or in part, by the co-administrated therapeutic drug. Methods of manufacturing the formulations are likewise described.
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公开(公告)号：US20180071264A1
公开(公告)日：2018-03-15
申请号：US15693223
申请日：2017-08-31
CPC分类号： A61K31/4188 , A61K8/19 , A61K8/673 , A61K9/0053 , A61K9/2086 , A61K9/28 , A61K9/2806 , A61K2800/58 , A61Q3/00 , A61Q5/002 , A61Q7/00
摘要： The present application relates to magnesium biotinate compositions and methods of use. The methods and compositions disclosed herein are particularly useful for providing bioavailable biotin to mammals and treating or preventing symptoms of biotin deficiency.
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