公开(公告)号：US12102789B1

公开(公告)日：2024-10-01

申请号：US18618798

申请日：2024-03-27

Applicant: Jubilant Draximage Inc.

Inventor： James A. Kaufman ,  Dominic Siewko ,  Indranil Nandi

IPC: A61M5/142 ,  A61M5/168 ,  A61M5/178 ,  G16H10/60 ,  G16H40/63

CPC classification number: A61M5/142 ,  A61M5/16831 ,  A61M5/1785 ,  G16H10/60 ,  G16H40/63 ,  A61M2005/14208 ,  A61M2005/16863 ,  A61M2202/0007 ,  A61M2202/049 ,  A61M2205/10 ,  A61M2205/18 ,  A61M2205/3327 ,  A61M2205/3331 ,  A61M2205/3379 ,  A61M2205/502 ,  A61M2205/584 ,  A61M2205/6009

Abstract: The invention is a theranostic delivery system or radiopharmaceutical drugs delivery system with movable workstation having handles. The workstation of theranostic delivery system or radiopharmaceutical drugs delivery system also has an on-board shielded disposal system for waste collection, which is operated by foot actuated system for locked and unlocked modes during the device journey. The theranostic delivery system or radiopharmaceutical drugs delivery system comprises a status light system that illuminates the working area to enable distance monitoring. Further, the delivery system includes a disposable secondary containment system that protects the core workstation from contamination, a configurable dose transporter and a disposable sealed fluid cartridge to withdraw custom volume from the vial or syringe. The delivery system includes a theranostic informatics management system, which contains a computer screen as a graphical user interface with a retractable rotating arm to receive the various patient infusion parameters.

公开(公告)号：US11865304B1

公开(公告)日：2024-01-09

申请号：US17175809

申请日：2021-02-15

Applicant: James R Crowley

Inventor： James R Crowley

IPC: A61M5/20 ,  A61M5/178 ,  A61M5/168

CPC classification number: A61M5/1785 ,  A61M5/16886 ,  A61M5/20 ,  A61M2205/3331

Abstract: Certain configurations of devices and systems that can administer a nuclear medication in an automated manner are described. In some instances, the system can receive a nuclear medication in a shielded transport container and administer the nuclear medication to a patient through an intravenous line in an automated manner to minimize radiation exposure by staff. Methods of using the devices and systems are also described.

公开(公告)号：US20190240394A1

公开(公告)日：2019-08-08

申请号：US16384410

申请日：2019-04-15

Applicant: Genentech, Inc.

Inventor： Joshua Horvath ,  Lionel Vedrine ,  Nathan A. Goltz ,  Mukund R. Patel ,  Aaron D. Chesterman ,  Mayumi Naito Bowen

IPC: A61M5/00 ,  A61L31/04 ,  A61M5/20 ,  A61M5/145 ,  A61L2/08

CPC classification number: A61M5/001 ,  A61L2/08 ,  A61L2/087 ,  A61L31/048 ,  A61L2202/14 ,  A61L2202/181 ,  A61L2202/24 ,  A61M5/002 ,  A61M5/14586 ,  A61M5/1785 ,  A61M5/2033 ,  A61M2005/31588 ,  A61M2202/0413 ,  A61M2202/0486 ,  A61M2202/09 ,  A61M2205/0272

Abstract: Apparatus and methods for delivering medicament to a patient. The apparatus may include elements with different capacities to attenuate or absorb sterilizing radiation. The apparatus may include a medicament delivery assembly with interactive elements for dose-setting, priming and medicament ejection. The assembly may include a chamber housing a radiation-sensitive medicament present in the apparatus during sterilization by electron beam. The assembly may include an actuator chassis, a drive mechanism, a needle-priming mechanism and a fluid-displacement mechanism including a fluid-displacement member. The chassis may be fixed, relative to an outlet, to the chamber. The member may be slidingly and/or threadingly engaged with the chassis, and may be configured to move relative to the outlet to deliver the medicament through the outlet. Assembly elements may be nested coaxially and/or stacked axially. The assembly may include at least one hollow region. The hollow region may reduce beam attenuation or reduce radiation absorption.

公开(公告)号：US09808578B2

公开(公告)日：2017-11-07

申请号：US14679756

申请日：2015-04-06

Applicant: Gabriel Institute, Inc.

Inventor： Stanley D. Stearns ,  H. Max Loy, Jr. ,  Donald G. Davis

IPC: A61M5/00 ,  A61M5/28 ,  A61M5/48 ,  A61M5/172 ,  A61M5/178 ,  A61M5/20 ,  A61M5/32 ,  A61M5/46 ,  A61M5/168

CPC classification number: A61M5/284 ,  A61M5/16886 ,  A61M5/172 ,  A61M5/1785 ,  A61M5/2053 ,  A61M5/32 ,  A61M5/46 ,  A61M5/484 ,  A61M2202/049 ,  A61M2205/3334 ,  A61M2206/20

Abstract: A dispensing device which disperses medicate through a needle across a zone within a body. The device includes a needle which is, during use, becomes encapsulated within a tubular needle-receiving member, a reservoir in fluid communication with the needle, positioned within the housing, and in communication with the needle, a second reservoir, a reservoir-connecting conduit in communication with the reservoir, a fluid drive in communication with the fluid in the second reservoir and in communication with the reservoir-connecting conduit, and a linear drive attached to the needle or to the needle-receiving member. The fluid drive impel fluids from the second reservoir to the reservoir-connecting conduit and thus drives the therapeutic agent from the reservoir during the linear displacement of the needle towards the housing. Fluid communication from the therapeutic agent reservoir to the needle is maintained by the tubing during operation of the linear drive.

公开(公告)号：US09757591B2

公开(公告)日：2017-09-12

申请号：US13764426

申请日：2013-02-11

Applicant: MEDRAD, INC.

Inventor： James A. Agamaite

IPC: A61M36/04 ,  A61N5/10 ,  A61M5/14 ,  A61M5/00 ,  A61M5/168 ,  G06F19/00 ,  A61M5/158 ,  A61M5/178

CPC classification number: A61N5/1075 ,  A61M5/007 ,  A61M5/14 ,  A61M5/16831 ,  A61M5/1785 ,  A61M2005/1588 ,  A61M2202/049 ,  A61M2205/15 ,  A61M2205/18 ,  A61M2205/3306 ,  A61M2205/3317 ,  A61M2205/3327 ,  A61M2205/3331 ,  A61M2205/3334 ,  A61M2205/3368 ,  A61M2205/3375 ,  A61M2205/3379 ,  A61M2205/3553 ,  A61M2205/3561 ,  A61M2205/3584 ,  A61M2205/3592 ,  A61M2205/50 ,  A61M2205/502 ,  A61M2205/505 ,  A61N5/1007 ,  G06F19/00 ,  G06F19/3468

Abstract: Methods and systems for monitoring an automated radiopharmaceutical infusion apparatus are disclosed. A user interface graphically representing infusion apparatus components may be presented on a display device. Multiple sensors may be arranged within an infusion apparatus to measure property information associated with infusion apparatus components, including fluid pathways. The property information may include radioactivity and flow information. The property information may be compared with expected results. If the property information does not match the expected results, a fault condition may be indicated on the display device. The user interface may provide information and/or functions to manage the fault conditions.

公开(公告)号：US09757306B2

公开(公告)日：2017-09-12

申请号：US14775988

申请日：2014-03-10

Applicant: BAYER MEDICAL CARE INC.

Inventor： Bruno Fazi ,  Jason L. Bazala ,  Arthur E. Uber, III

IPC: G21F5/12 ,  F16L39/00 ,  A61J1/16 ,  B65D77/04 ,  B65D51/00 ,  B65D53/02 ,  G21F5/015 ,  A61M5/178

CPC classification number: A61J1/16 ,  A61M5/1785 ,  B65D51/00 ,  B65D53/02 ,  B65D77/0486 ,  B65D2313/04 ,  G21F5/015

Abstract: Vial containers including a collar which is attached to a vial or incorporated into a vial cap, a cap designed to receive a portion of the collar while covering the vial, and a container designed to receive a portion of the collar and encase the body of the vial are described herein. The collar, generally, includes a means for reversibly attaching to the cap and container.

公开(公告)号：US20160346455A1

公开(公告)日：2016-12-01

申请号：US15230772

申请日：2016-08-08

Applicant: BAYER HEALTHCARE LLC

Inventor： Kevin P. COWAN

IPC: A61M5/00 ,  A61M5/31 ,  A61M5/315 ,  A61M5/19

CPC classification number: A61M5/007 ,  A61M5/1785 ,  A61M5/19 ,  A61M5/20 ,  A61M5/3137 ,  A61M5/31513 ,  A61M5/31561 ,  A61M5/31563 ,  A61M5/31583 ,  A61M5/31596 ,  A61M2005/1787 ,  A61M2005/3128 ,  A61M2005/3139 ,  A61M2005/31598 ,  A61M2205/50 ,  A61M2205/505 ,  A61M2205/52

Abstract: Adjustable volume syringes, and systems and methods for using the same, are disclosed. An adjustable volume syringe may include a delivery syringe, a reservoir syringe located at least in part within the delivery syringe, and a reservoir plunger located at least in part within the reservoir syringe. The delivery syringe may be configured to contain a first amount of a fluid and the reservoir syringe may be configured to contain a second amount of the fluid. An administration amount of the fluid may be determined at or prior to an administration time, and the amount of fluid in the delivery syringe may be adjusted to equal the administration amount by adding fluid from the reservoir syringe to the delivery syringe or by withdrawing fluid from the delivery syringe to into the reservoir syringe. The administration amount of fluid may be dispensed to a patient at the administration time.

Abstract translation: 公开了可调节的体积注射器，以及用于其的系统和方法。 可调节体积的注射器可以包括递送注射器，至少部分地位于递送注射器内的储存器注射器，以及至少部分地位于储存器注射器内的储存器柱塞。 输送注射器可以构造成容纳第一量的流体，并且储存器注射器可以被构造成容纳第二量的流体。 可以在给药时间之前或之前确定流体的给药量，并且可以通过将来自储存器注射器的流体添加到递送注射器或通过从流体中抽出流体来将输送注射器中的流体的量调节至等于施用量 输送注射器进入储液器注射器。 可以在给药时间将流体的给药量分配给患者。

公开(公告)号：US09408981B2

公开(公告)日：2016-08-09

申请号：US13792158

申请日：2013-03-10

Applicant: MEDRAD, INC.

Inventor： Kevin P. Cowan

IPC: A61M31/00 ,  A61M5/315 ,  A61M5/178 ,  A61M5/20

CPC classification number: A61M5/007 ,  A61M5/1785 ,  A61M5/19 ,  A61M5/20 ,  A61M5/3137 ,  A61M5/31513 ,  A61M5/31561 ,  A61M5/31563 ,  A61M5/31583 ,  A61M5/31596 ,  A61M2005/1787 ,  A61M2005/3128 ,  A61M2005/3139 ,  A61M2005/31598 ,  A61M2205/50 ,  A61M2205/505 ,  A61M2205/52

Abstract: Adjustable volume syringes and systems are disclosed. An adjustable volume syringe includes a delivery syringe barrel, a reservoir syringe barrel positioned at least partially within the delivery syringe barrel, and a reservoir plunger positioned at least partially within the reservoir syringe barrel. The delivery syringe barrel is configured to contain a first amount of a fluid. The reservoir syringe barrel is configured to contain a second amount of the fluid. A system includes the adjustable volume syringe, a dispensing module in communication with the syringe, and a processor in communication with the dispensing module. The processor may be configured to determine an administration amount of the fluid in the adjustable volume syringe, and transmit signals causing the dispensing module to adjust the volume of fluid in the syringe to the administration amount and deliver the administration amount by moving the reservoir syringe barrel with respect to the delivery syringe barrel.

Abstract translation: 公开了可调节的体积注射器和系统。 可调节体积的注射器包括输送注射器筒，至少部分地定位在递送注射器筒内的储存器注射器筒，以及至少部分地位于储存器注射器筒内的储存器柱塞。 输送注射器筒构造成容纳第一量的流体。 储存器注射器筒构造成容纳第二量的流体。 系统包括可调节体积注射器，与注射器连通的分配模块以及与分配模块连通的处理器。 处理器可以被配置为确定可调节体积注射器中的流体的管理量，并且传输使得分配模块将注射器中的流体的体积调节到管理量的信号，并且通过移动储存器注射器筒 相对于输送注射器筒。

公开(公告)号：US20140046295A1

公开(公告)日：2014-02-13

申请号：US13971095

申请日：2013-08-20

Applicant: Medrad, Inc.

Inventor： Arthur E. Uber, III ,  Mark Trocki ,  Marc A. Mabie ,  Larry McCutchan ,  L. George Siddoway ,  Kevin P. Cowan ,  Lisa M. Coates ,  John F. Kalafut ,  Aaron Hughes ,  David M. Griffiths ,  Peter Twichell ,  Julie Gulick ,  Frederick W. Trombley, III

IPC: A61N5/10

CPC classification number: A61N5/1007 ,  A61M5/007 ,  A61M5/16827 ,  A61M5/1785 ,  A61M2005/1402 ,  A61M2202/0225 ,  A61M2202/049 ,  A61M2206/11 ,  A61M2206/18 ,  Y10T137/0318

Abstract: A hazardous fluid transport container and a hazardous fluid delivery system are disclosed. The hazardous fluid transport container includes a housing enclosing an at least partially shielded enclosure. First and second fluid path elements are disposed within the housing, with the first fluid path element and second fluid path element fluidly coupled together. A pump unit may be provided for dispensing fluid from the first and second fluid path elements optionally into a third fluid path element. Also, methods for priming the hazardous fluid transport container and for mitigating laminar flow injection bolus spreading are disclosed. Additionally, disclosed is a radioactive fluid transport container for a syringe or other container. The radioactive fluid transport container allows the syringe or container to be used in an injection procedure without removal from the container.

Abstract translation: 公开了一种危险流体输送容器和危险流体输送系统。 危险流体输送容器包括封闭至少部分屏蔽的外壳的壳体。 第一和第二流体通道元件设置在壳体内，第一流体路径元件和第二流体路径元件流体耦合在一起。 可以提供泵单元，用于将流体从第一和第二流体路径元件任选地分配到第三流体路径元件中。 此外，公开了用于引燃危险流体输送容器和减轻层流注射团块扩散的方法。 此外，公开了一种用于注射器或其他容器的放射性流体输送容器。 放射性流体输送容器允许注射器或容器在注射过程中使用而不从容器中取出。

公开(公告)号：US20130317277A1

公开(公告)日：2013-11-28

申请号：US13984402

申请日：2012-02-09

Applicant: Pierre-Marie Lemer

Inventor： Pierre-Marie Lemer

IPC: A61N5/10

CPC classification number: A61N5/1002 ,  A61M5/1785 ,  A61M2205/6081 ,  G21F5/018 ,  G21F5/08

Abstract: A protection device to be fitted onto a syringe (2) used for injecting radioactive material(s). The radiation protection device includes a tubular radiation protection housing (1) that includes an outer tubular part (15), which constitutes at least a portion of the outer surface (11) thereof, and which is made of an elastomeric material. The tubular portion (15) also includes an annular constrictive portion (20) including a resiliently deformable inner surface that is used to apply a compressive force around the cylindrical body (3) of the inserted syringe (2).

Abstract translation: 安装在用于注射放射性物质的注射器（2）上的保护装置。 辐射防护装置包括管状辐射防护壳体（1），其包括构成其外表面（11）的至少一部分并且由弹性体材料制成的外管状部件（15）。 管状部分（15）还包括环形收缩部分（20），其包括可弹性变形的内表面，用于在插入的注射器（2）的圆柱体（3）周围施加压缩力。