公开(公告)号：US11865243B2

公开(公告)日：2024-01-09

申请号：US16328443

申请日：2017-08-30

申请人： NxStage Medical, Inc.

发明人： Mark T. Wyeth ,  Robert Paul McCarty ,  Gregory Yantz ,  James Ian Johnson ,  Joseph E. Turk, Jr. ,  James M. Brugger ,  Jeffrey H. Burbank

IPC分类号： A61M1/36 ,  A61M1/16

CPC分类号： A61M1/3639 ,  A61M1/1611 ,  A61M1/1621 ,  A61M1/3623 ,  A61M2205/3344 ,  A61M2205/52 ,  A61M2230/207

摘要： A blood treatment system with pressure sensors may be configured to control blood flow to and from the patient and use readings of the pressure sensors to determine a change in a pressure drop across a flow restriction in the blood circuit to estimate a condition of the machine or the patient, or outputting data responsive to the estimation. Further embodiments employ measurement of pressure drop to detect abnormal viscosity or viscosity variations in order to detect possible infection.

公开(公告)号：US20180221554A1

公开(公告)日：2018-08-09

申请号：US15872363

申请日：2018-01-16

申请人： Medtronic, Inc.

发明人： Michael J. M. Mazack ,  Eric A. Grovender ,  Bryant J. Pudil

IPC分类号： A61M1/16 ,  A61M1/26

CPC分类号： A61M1/1603 ,  A61M1/1605 ,  A61M1/1607 ,  A61M1/1611 ,  A61M1/1613 ,  A61M1/1656 ,  A61M1/1696 ,  A61M1/267 ,  A61M2205/3317 ,  A61M2205/3324 ,  A61M2205/3334 ,  A61M2205/3368 ,  A61M2205/3379 ,  A61M2205/50 ,  A61M2230/20

摘要： The invention relates to devices, systems, and methods for managing base levels, specifically bicarbonate, in an individual undergoing dialysis. The devices, systems, and methods can be compatible with a sorbent-based dialysis therapy, and open loop control of base levels in the dialysis, without sensors or feedback for controlling the introduction of bicarbonate into the dialysate. The bicarbonate levels can be controlled and personalized to a patient using certain predetermined patient parameters. Related systems, algorithms, and control systems are contemplated including the specific predetermined parameters predictive of post-dialysis bicarbonate levels.

公开(公告)号：US09675294B2

公开(公告)日：2017-06-13

申请号：US14345856

申请日：2012-09-18

申请人： Fresenius Medical Care Holdings, Inc. ,  Fresenius Medical Care Deutschland, GMBH

发明人： Nathan W. Levin ,  Fansan Zhu ,  Peter Kotanko ,  Peter Wabel ,  Ciro Tetta

IPC分类号： A61B5/00 ,  A61M1/16 ,  A61B5/053 ,  A61B5/0205 ,  A61B5/0295 ,  A61B5/1455 ,  A61B6/00 ,  A61B5/021 ,  A61B5/026 ,  A61B8/08

CPC分类号： A61M1/1611 ,  A61B5/0205 ,  A61B5/021 ,  A61B5/0261 ,  A61B5/028 ,  A61B5/0295 ,  A61B5/0537 ,  A61B5/08 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/4839 ,  A61B5/4875 ,  A61B5/4878 ,  A61B6/50 ,  A61B8/0891 ,  A61B8/5223 ,  A61M1/16 ,  A61M2205/3303 ,  A61M2205/3317 ,  A61M2230/04 ,  A61M2230/20 ,  A61M2230/65

摘要： In an embodiment, the invention relates to methods, apparatus, computer programs and computer program products for estimating a dry weight of a dialysis patient comprising the steps of determining a first fluid status of the patient between treatment sessions in a first stage, determining a second fluid status of the patient during treatment sessions in a second stage and estimating the dry weight based on the second fluid status.

公开(公告)号：US20150367056A1

公开(公告)日：2015-12-24

申请号：US14644820

申请日：2015-03-11

申请人： Medtronic, Inc.

发明人： Martin T. Gerber ,  Christopher M. Hobot

IPC分类号： A61M1/16 ,  B01D15/08

CPC分类号： A61M1/1696 ,  A61M1/1611 ,  A61M1/1613 ,  A61M2205/121 ,  A61M2205/33 ,  B01D15/08

摘要： A customizable modular dialysate regeneration assembly with connectable sorbent packaging systems. The dialysate regeneration assembly can be customized based on patient parameters or dialysis session parameters. A processor can be included that can determine the correct amount of each sorbent material necessary for a given patient and a given dialysis session.

摘要翻译： 可定制的模块化透析液再生组件，具有可连接的吸附剂包装系统。 可以根据患者参数或透析会话​​参数来定制透析液再生组件。 可以包括可以确定给定患者和给定透析会话所需的每种吸着剂材料的正确量的处理器。

公开(公告)号：US20150224241A1

公开(公告)日：2015-08-13

申请号：US14429435

申请日：2013-09-19

申请人： GAMBRO LUNDIA AB

发明人： Francesco Fontanazzi ,  Francesco Paolini ,  Fabio Grandi

IPC分类号： A61M1/16 ,  A61M1/36

CPC分类号： A61M1/1611 ,  A61M1/34 ,  A61M1/3403 ,  A61M1/3413 ,  A61M1/3434 ,  A61M1/3437 ,  A61M1/3441 ,  A61M1/3607 ,  A61M1/3609 ,  A61M1/3687 ,  A61M2205/3306 ,  A61M2205/3331 ,  A61M2205/50 ,  A61M2205/502 ,  A61M2205/505

摘要： An apparatus for extracorporeal blood treatment comprises a sensor (10) for emitting a signal indicating a variation in blood volume (ΔBv″) of an individual (7) subjected to extracorporeal blood treatment and a sensor (14) for emitting a signal indicating a weight loss of the individual. A control unit (20) receives the signals, compares the ratio between the relative variation of blood volume (ΔBv/BV) and the relative variation of weight loss (AWL/TW) of the individual with a desired value, and controls the weight loss of the individual on the basis of the comparison. The apparatus enables automatically controlling a dialysis, preventing some complications due to hypotension.

摘要翻译： 一种用于体外血液处理的装置，包括用于发出指示经受体外血液处理的个人（7）的血容量变化（＆Dgr; Bv“）的信号的传感器（10），以及用于发出指示 个体减肥。 控制单元（20）接收信号，比较具有期望值的个体的血量（＆Dgr; Bv / BV）的相对变化与体重减轻的相对变化（AWL / TW）之间的比例，并且控制 在减肥的基础上比较。 该装置能够自动控制透析，防止由于低血压引起的一些并发症。

公开(公告)号：US08868350B2

公开(公告)日：2014-10-21

申请号：US13088044

申请日：2011-04-15

申请人： Alp Akonur ,  John Kenneth Leypoldt ,  Ying-Cheng Lo ,  Baris Ugur Agar

发明人： Alp Akonur ,  John Kenneth Leypoldt ,  Ying-Cheng Lo ,  Baris Ugur Agar

IPC分类号： G01N33/48 ,  A61M1/16 ,  A61M1/36 ,  G06F19/00

CPC分类号： A61M1/1603 ,  A61M1/16 ,  A61M1/1611 ,  A61M1/1613 ,  A61M1/1619 ,  A61M1/3609 ,  A61M2202/0498 ,  A61M2205/15 ,  A61M2205/3584 ,  A61M2205/50 ,  A61M2205/502 ,  A61M2205/52 ,  A61M2230/20 ,  G06F19/3481

摘要： A method of predicting serum phosphorus concentrations in a patient during hemodialysis includes measuring serum phosphorus concentrations of the patient over a hemodialysis treatment session time and an ultrafiltration rate calculated by a difference between pre- and post-dialytic body weight of the patient during an initial hemodialysis treatment session divided by a total treatment time of the treatment session and estimating a phosphorous mobilization clearance and a pre-dialysis distribution volume of phosphorus for the patient. Serum phosphorus concentrations of the patient can then be predicted at any time during any hemodialysis treatment session with the estimated phosphorous mobilization clearance and pre-dialysis distribution volume of phosphorus of the patient.

公开(公告)号：US08845570B2

公开(公告)日：2014-09-30

申请号：US13088064

申请日：2011-04-15

申请人： Alp Akonur ,  John Kenneth Leypoldt ,  Ying-Cheng Lo ,  Baris Ugar Agar

发明人： Alp Akonur ,  John Kenneth Leypoldt ,  Ying-Cheng Lo ,  Baris Ugar Agar

IPC分类号： A61M37/00 ,  A61M1/16 ,  A61M1/36 ,  G06F19/00

CPC分类号： A61M1/1603 ,  A61M1/16 ,  A61M1/1611 ,  A61M1/1613 ,  A61M1/1619 ,  A61M1/3609 ,  A61M2202/0498 ,  A61M2205/15 ,  A61M2205/3584 ,  A61M2205/50 ,  A61M2205/502 ,  A61M2205/52 ,  A61M2230/20 ,  G06F19/3481

摘要： A method of predicting serum phosphorus concentrations in a patient during hemodialysis includes measuring serum phosphorus concentrations of the patient over a hemodialysis treatment session time and an ultrafiltration rate calculated by a difference between pre- and post-dialytic body weight of the patient during an initial hemodialysis treatment session divided by a total treatment time of the treatment session and estimating a phosphorous mobilization clearance and a pre-dialysis distribution volume of phosphorus for the patient. Serum phosphorus concentrations of the patient can then be predicted at any time during any hemodialysis treatment session with the estimated phosphorous mobilization clearance and pre-dialysis distribution volume of phosphorus of the patient.

摘要翻译： 在血液透析期间预测患者血清磷浓度的方法包括测量血液透析治疗会话时间的患者的血清磷浓度，以及通过初始血液透析期间患者的透析前和透析后体重之间的差异计算的超滤率 治疗时间除以治疗会话的总治疗时间，并估计患者的磷的移动清除率和磷酸盐的透析前分布体积。 然后可以在任何血液透析治疗期间的任何时间预测患者的血清磷浓度，其中估计磷移动清除率和患者的磷的透析前分布体积。

公开(公告)号：US20110017667A1

公开(公告)日：2011-01-27

申请号：US12843679

申请日：2010-07-26

申请人： Michael J. Delmage ,  Harold Peters ,  Tommy Cooper ,  Steve Macha

发明人： Michael J. Delmage ,  Harold Peters ,  Tommy Cooper ,  Steve Macha

IPC分类号： B01D61/32

CPC分类号： A61M1/34 ,  A61M1/16 ,  A61M1/1611 ,  A61M1/342 ,  A61M2205/12 ,  A61M2205/18 ,  A61M2205/33 ,  A61M2205/3334 ,  A61M2205/3379 ,  A61M2205/502

摘要： An apparatus configured for carrying out CRRT on patients weighing up to about 20 kg incorporates a control unit having a blood pump and a plurality of fluid pumps mounted thereon, and a controller configured for operating the blood pump and fluid pumps, and an interactive operator control system including an operator interface screen operatively connected to the controller, the controller including software configured to operate the apparatus in response to operator input selections. The interactive operator control system includes operator inputs for setting patient weight, blood pump flow rate and fluid pump flow rates and the controller is configured to calculate and display maximum allowable fluid gain or loss based solely on patient weight settings between zero kg and about 20 kg and trigger warnings and alarms for selected or calculated levels of patient fluid gain or loss and stop operation of the pumps or termination of CRRT in response to patient fluid gain or loss in excess of the maximum.

摘要翻译： 一种被配置为对重达20kg的患者执行CRRT的装置包括具有血泵和安装在其上的多个流体泵的控制单元，以及配置用于操作血泵和流体泵的控制器，以及交互操作器控制 系统，其包括操作地连接到控制器的操作员界面屏幕，所述控制器包括被配置为响应于操作者输入选择来操作所述设备的软件。 交互式操作员控制系统包括用于设置患者体重，血泵流量和流体泵流量的操作者输入，并且控制器被配置为仅基于零kg和约20kg之间的患者体重设置来计算和显示最大允许流体增益或损失 并针对患者流体增益或损失的选定或计算水平触发警告和警报，并响应患者流体增益或损失超过最大值，停止泵的运行或终止CRRT。

公开(公告)号：US20100137693A1

公开(公告)日：2010-06-03

申请号：US12620283

申请日：2009-11-17

申请人： Alexis Porras ,  Ravi Kalathil ,  Darrell Kauthen ,  Theresa J. Hetzel

发明人： Alexis Porras ,  Ravi Kalathil ,  Darrell Kauthen ,  Theresa J. Hetzel

IPC分类号： A61B5/00 ,  G06Q50/00

CPC分类号： A61M1/16 ,  A61M1/1611 ,  A61M1/3609 ,  A61M2205/3331 ,  A61M2205/3553 ,  A61M2205/3584 ,  A61M2205/505 ,  A61M2205/59 ,  G06F19/3418 ,  G06F19/3481 ,  G06Q50/22 ,  G06Q50/24 ,  G09B5/02 ,  G16H40/63

摘要： Methods and apparatus for patient care detect a current medical condition of a patient receiving medical treatment, e.g., by sensing blood pressure, heart rate, weight, glucose level, hemoglobin level, and/or blood potassium level (all by way of example) and transmit information regarding that medical condition to a digital data processing system disposed remotely from the medical treatment apparatus. The medical treatment apparatus can be, for example, one for peritoneal dialysis and hemodialysis, and the medical condition can be sensed by sensors coupled to or otherwise utilized in connection with such apparatus.

摘要翻译： 用于患者护理的方法和装置检测接受治疗的患者的当前医疗状况，例如通过感测血压，心率，体重，葡萄糖水平，血红蛋白水平和/或血钾水平（全部通过实例）和 将关于该医疗状况的信息发送到远离医疗设备设置的数字数据处理系统。 医疗处理装置可以是例如用于腹膜透析和血液透析的医疗装置，并且医疗状况可以由耦合到或以其他方式与这种装置结合使用的传感器感测。

公开(公告)号：US20100016777A1

公开(公告)日：2010-01-21

申请号：US12536412

申请日：2009-08-05

申请人： Jeffrey H. Burbank ,  James M. Brugger

发明人： Jeffrey H. Burbank ,  James M. Brugger

IPC分类号： A61M1/14

CPC分类号： A61M1/16 ,  A61M1/1601 ,  A61M1/1611 ,  A61M1/1643 ,  A61M2205/3331 ,  A61M2205/3334 ,  A61M2205/3382 ,  A61M2205/3386 ,  A61M2205/50 ,  A61M2205/52

摘要： One or more waste balancing systems may be used in a fluid circulating system for medical use. The fluid circulating system may be part of a blood treatment system for a patient suffering renal failure. A waste balancing system may include a pressure element operable to maintain a constant fluid pressure created by the combined weight of waste removed from a patient and replacement fluid for providing to a patient. Multiple evaluation characteristics or control parameters may be evaluated or controlled for safety and accuracy. At least part of the waste balancing system may be incorporated into a disposable cartridge.

摘要翻译： 在用于医疗用途的流体循环系统中可以使用一个或多个废物平衡系统。 流体循环系统可以是患有肾衰竭的患者的血液处理系统的一部分。 废物平衡系统可以包括压力元件，其可操作以保持由从患者移除的废物的组合重量产生的恒定的流体压力和用于提供给患者的替换流体。 可以评估或控制多个评估特性或控制参数的安全性和准确性。 废物平衡系统的至少一部分可以结合到一次性盒中。