公开(公告)号：US20240215846A1

公开(公告)日：2024-07-04

申请号：US18279682

申请日：2022-02-18

Applicant: Hamilton Medical AG

Inventor： David Schwenninger

IPC: A61B5/03 ,  A61B5/00

CPC classification number: A61B5/037 ,  A61B5/6853 ,  A61B2560/0223

Abstract: The invention relates to a calibration system for automatically setting an intended operational filling of an esophageal catheter with balloon probe, which can be inserted into the esophagus, for determining an esophageal pressure, in particular for a ventilation device, comprising a device for filling the balloon probe with a measuring fluid after placing the balloon probe in the esophagus, a pressure sensor for detecting the esophageal pressure prevailing in the balloon probe, and a calibration controller which is designed such that it incrementally changes the amount of measuring fluid in the balloon probe, the calibration controller recording an esophageal pressure detected by the pressure sensor for each amount of measuring fluid in the balloon probe set incrementally as a measuring point in this way and assigning said esophageal pressure to the respective set amount of measuring fluid in the balloon probe. The calibration controller is designed such that, in order to approach the respective measuring points, it monotonically changes the amount of measuring fluid in at least two steps, starting from a start value until an end value is reached.

公开(公告)号：US20240041343A1

公开(公告)日：2024-02-08

申请号：US18546592

申请日：2022-02-16

Applicant: Northwestern University

Inventor： John Erik Pandolfino ,  Dustin Allan Carlson ,  Wenjun Kou

IPC: A61B5/03 ,  A61B5/00 ,  A61M25/10 ,  A61B5/11

CPC classification number: A61B5/037 ,  A61B5/7267 ,  A61M25/1011 ,  A61B5/1107 ,  A61B5/687 ,  A61B5/6853 ,  A61B2562/0247

Abstract: A catheter-based baro-hydrometer device measures or otherwise monitors esophageal function. The device includes a segmented balloon design, including a first and second balloon whose fill volumes can be independently controlled. In general, the device leverages secondary peristalsis related to balloon distention in order to study esophageal function. Pressure sensors coupled to the balloons record pressure data, which can be classified and processed to measure or otherwise monitor esophageal function.

公开(公告)号：US20230414163A1

公开(公告)日：2023-12-28

申请号：US18034758

申请日：2021-10-01

Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

Inventor： Ali ZIFAN ,  Ravinder K. MITTAL

IPC: A61B5/00 ,  A61B5/0538 ,  A61B5/107 ,  A61B5/03 ,  A61B5/0536 ,  A61B5/11

CPC classification number: A61B5/4205 ,  A61B5/0538 ,  A61B5/4233 ,  A61B5/7425 ,  A61B5/037 ,  A61B5/0536 ,  A61B5/1107 ,  A61B5/1076

Abstract: Intraluminal impedance recordings are used to calculate luminal cross-sectional area, or in other words, distension of the esophagus/gastrointestinal tract, during peristalsis using various recording protocols and algorithms derived using the Ohm's law of electricity. Additionally, multiple visual displays of distension-contraction plots of esophageal peristalsis are provided that allows both the relaxation and contraction phase of peristalsis to be easily assessed. These distension-contraction plots can be used to diagnose disorders of the esophagus or other regions of the gastrointestinal tract that result in symptoms such as difficulty swallowing (dysphagia), heartburn, and chest pain, in the case of esophagus. Furthermore, the effects of pharmacological agents/drugs on the distension-contraction measurements can be studied using these protocols and algorithms to treat patients with esophageal symptoms.

公开(公告)号：US11707283B2

公开(公告)日：2023-07-25

申请号：US16854622

申请日：2020-04-21

Applicant: THE MEDICAL COLLEGE OF WISCONSIN, INC.

Inventor： Reza Shaker

IPC: A61B17/132 ,  A61B5/00 ,  A61B5/103 ,  A61F2/50 ,  A61B5/03 ,  A61B5/07 ,  A61B17/135 ,  A61B17/00

CPC classification number: A61B17/1325 ,  A61B5/0002 ,  A61B5/037 ,  A61B5/076 ,  A61B5/103 ,  A61B5/4211 ,  A61B5/4233 ,  A61B5/687 ,  A61B5/7246 ,  A61B17/1355 ,  A61F2/50 ,  A61B5/0053 ,  A61B2017/00022 ,  A61B2017/00827

Abstract: An esophageal device is used to recognize, diagnose, characterize, or relieve an impact of an abnormal or defective UES anatomy, physiology, or functionality. In one implementation, the esophageal device measures a UES response to esophageal fluid infusion to detect or characterize an abnormality or defective UES anatomy, physiology, or functionality. An Upper Esophageal Sphincter compression device is used to increase intra-luminal pressure within the Upper Esophageal Sphincter of a patient in order relieve an impact of an abnormal or defective UES anatomy, physiology, or functionality.

公开(公告)号：US20230181055A1

公开(公告)日：2023-06-15

申请号：US18079714

申请日：2022-12-12

Applicant: The Medical College of Wisconsin, Inc. ,  University of Southern California

Inventor： Reza Shaker ,  Anisa Shaker

IPC: A61B5/03 ,  A61B1/00 ,  A61B1/015 ,  A61M13/00 ,  A61B1/273

CPC classification number: A61B5/037 ,  A61B1/00165 ,  A61B1/015 ,  A61M13/003 ,  A61B1/0005 ,  A61B1/2736 ,  A61M2025/0002

Abstract: Disclosed is an endoscope for measuring intra-organ pressure (e.g., intragastric pressure), and more particularly an endoscope for measuring intra-organ pressure (e.g., intragastric pressure) and visualizing the response of an adjacent sphincter (e.g., lower esophageal sphincter) to changes in the intra-organ pressure.

公开(公告)号：US20190231202A1

公开(公告)日：2019-08-01

申请号：US16260358

申请日：2019-01-29

Applicant: Loewenstein Medical Technology S.A.

Inventor： Peter KREMEIER

IPC: A61B5/03 ,  A61B5/08 ,  A61B5/00 ,  A61M16/00

CPC classification number: A61B5/036 ,  A61B5/037 ,  A61B5/0803 ,  A61B5/0816 ,  A61B5/085 ,  A61B5/087 ,  A61B5/4836 ,  A61B5/6853 ,  A61B2562/0247 ,  A61J15/0003 ,  A61J15/0049 ,  A61J15/0073 ,  A61J15/0084 ,  A61M16/0003 ,  A61M16/0051 ,  A61M16/024 ,  A61M16/0434 ,  A61M16/044 ,  A61M25/10 ,  A61M25/1002 ,  A61M25/10184 ,  A61M2016/0027 ,  A61M2205/3334 ,  A61M2205/3344 ,  A61M2205/3553 ,  A61M2205/3561 ,  A61M2210/101 ,  A61M2210/105 ,  A61M2230/08 ,  A61M2230/40 ,  A61M2230/65

Abstract: The invention relates to a system for recording breathing efforts of a patient, which comprises a pressure determination device for determining a transpulmonary pressure at the point in time of the breathing effort of the patient. The invention moreover relates to a unit for recording the optimum filling volume of the balloon of an esophageal catheter.

公开(公告)号：US20180153473A1

公开(公告)日：2018-06-07

申请号：US15575625

申请日：2016-05-20

Applicant: Flip Technologies Limited

Inventor： John O'DEA

IPC: A61B5/00 ,  A61B5/053 ,  A61B5/02

CPC classification number: A61B5/6853 ,  A61B5/02007 ,  A61B5/02021 ,  A61B5/0215 ,  A61B5/037 ,  A61B5/0538 ,  A61B5/1076 ,  A61B5/4233 ,  A61B5/4519 ,  A61M2025/1022

Abstract: Apparatus (1) for rupturing muscle fibres in a lower oesophageal sphincter (2) comprises a balloon catheter (4) having a catheter (5) and a balloon (8) located at the distal end (7) of the catheter (5). A multi-electrode impedance planimetry measuring system (10) comprising a pair of stimulating electrodes (11) and sensing electrodes (12) is located on the catheter 5 within the balloon (8) for monitoring the diameter of the balloon (8) when the balloon (8) is inflated by a pump (25) with a liquid saline solution from a reservoir (26) through a flowmeter (33) under the control of a microprocessor (20). With the balloon (8) located in the sphincter (2) as the balloon (8) is being inflated, the microprocessor (8) computes the minimum diameter value of the balloon (8) from signals read from the sensing electrodes (12) each time the cumulative volume of the liquid saline solution in the balloon (8) increases by a predefined unit volume. The microprocessor computes a curve (40) of a plot of the minimum diameter values against the corresponding cumulative volume values of the liquid saline solution in the balloon (8) and determines the slope of the curve at each computed minimum diameter value. Rupture of the muscle fibres of the sphincter (2) is determined at the point of inflection (42) of the curve (40).

公开(公告)号：US20180153388A1

公开(公告)日：2018-06-07

申请号：US15369883

申请日：2016-12-05

Applicant: Alaaeldin Soliman

Inventor： Alaaeldin Soliman

IPC: A61B1/267 ,  A61B1/05 ,  A61B1/012 ,  A61B5/0402 ,  A61B5/042 ,  A61B5/03 ,  A61B7/04 ,  A61B1/273 ,  A61M16/04 ,  A61J15/00

CPC classification number: A61B1/267 ,  A61B1/012 ,  A61B1/05 ,  A61B1/2736 ,  A61B5/037 ,  A61B5/0421 ,  A61B5/6853 ,  A61B7/04 ,  A61J15/0003 ,  A61J15/0049 ,  A61J15/0073 ,  A61J15/0084 ,  A61J15/0088 ,  A61M16/0411 ,  A61M16/0415 ,  A61M16/0488 ,  A61M2205/32 ,  A61M2205/332 ,  A61M2205/3344 ,  A61M2205/3375 ,  A61M2205/502 ,  A61M2210/105 ,  A61M2230/04

Abstract: A patient monitoring, feeding, and mechanical breathing system, the system including an endotracheal probe including a first longitudinal member connected to a first camera and a semi-rigid longitudinal member inserted in an ET tube such that the first camera is aligned with a tip of the ET tube; an OG probe including a second longitudinal member configured to be inserted in an oral gastro (OG) tube, the second longitudinal member including a side camera, configured to be placed facing a window of the OG tube, wherein the side camera includes a tapered side; an enhanced OG probe, including a second camera and a motion sensor placed at the tip of the enhanced OG tube; a device communicatively coupled to the endotracheal, OG and enhanced OG probes, and having a screen configured to display images from any of the first camera, the side camera, and the second camera.

公开(公告)号：US09962108B2

公开(公告)日：2018-05-08

申请号：US14595491

申请日：2015-01-13

Applicant: GIVEN IMAGING LTD.

Inventor： John T Kilcoyne ,  Ross Tsukashima ,  George M Johnson ,  Christopher Klecher

IPC: A61B5/07 ,  A61B1/00 ,  A61B1/04 ,  A61B5/00 ,  A61B5/03 ,  A61B5/145

CPC classification number: A61B5/073 ,  A61B1/00147 ,  A61B1/041 ,  A61B5/0008 ,  A61B5/0031 ,  A61B5/037 ,  A61B5/14532 ,  A61B5/14539 ,  A61B5/14546 ,  A61B5/42 ,  A61B5/4233 ,  A61B5/6882

Abstract: Disclosed is an ambulatory system for monitoring one or more physiological parameters in a body lumen, such as the esophagus. The system includes an implantable probe having a sensor for the physiological parameter and a transmitter for transmitting data to an external receiver. The probe may be used for monitoring any of various physiological parameters, including pH, temperature, and pressure, within the esophagus or other body lumens. Methods and deployment catheters are also disclosed.

公开(公告)号：US20180085576A1

公开(公告)日：2018-03-29

申请号：US15696376

申请日：2017-09-06

Applicant: EndoStim, Inc.

Inventor： Virender K. Sharma ,  Matt Joseph Gani ,  Paul V. Goode ,  Bevil Hogg ,  Jay Miazga ,  Shai Policker ,  Kaila Raby

IPC: A61N1/36 ,  A61N1/372 ,  A61B5/145 ,  A61B5/00 ,  A61B5/053 ,  A61B5/03 ,  A61B5/11

CPC classification number: A61B5/0031 ,  A61B5/037 ,  A61B5/0538 ,  A61B5/1116 ,  A61B5/14539 ,  A61B5/4211 ,  A61B5/4836 ,  A61N1/36007 ,  A61N1/3606 ,  A61N1/36139 ,  A61N1/36157 ,  A61N1/36171 ,  A61N1/36175 ,  A61N1/37235

Abstract: The present specification discloses devices and methodologies for the treatment of transient lower esophageal sphincter relaxations (tLESRs). Individuals with tLESRs may be treated by implanting a stimulation device within the patient's lower esophageal sphincter and applying electrical stimulation to the patient's lower esophageal sphincter, in accordance with certain predefined protocols. The presently disclosed devices have a simplified design because they do not require sensing systems capable of sensing when a person is engaged in a wet swallow and have improved energy storage requirements.