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公开(公告)号:US12201684B2
公开(公告)日:2025-01-21
申请号:US16937967
申请日:2020-07-24
Inventor: Burton Dickey , Michael Tuvim , Scott Evans
Abstract: Embodiments of the invention are directed to methods of treating, inhibiting or attenuating a microbial infection in an individual who has or is at risk for developing such an infection, comprising the step of administering an effective amount of a StIR composition to the individual.
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公开(公告)号:US12060868B2
公开(公告)日:2024-08-13
申请号:US17504305
申请日:2021-10-18
Inventor: Na Li , Carter S. Haines , Marcio D. Lima , Monica Jung DeAndrade , Shaoli Fang , Jiyoung Oh , Mikhail E. Kozlov , Dongseok Suh , Ray H. Baughman
IPC: F03G7/06 , D01D5/00 , D01F6/00 , D01H1/10 , D02G3/02 , D02G3/26 , D02G3/44 , D04C1/02 , H02N10/00 , H02N11/00
CPC classification number: F03G7/06 , D01D5/0007 , D01F6/00 , D01H1/10 , D02G3/02 , D02G3/26 , D02G3/448 , D04C1/02 , H02N10/00 , H02N11/006 , D10B2401/046 , D10B2401/061 , D10B2509/00 , Y10T428/249921 , Y10T428/2925
Abstract: Actuators (artificial muscles) comprising twisted polymer fibers generate tensile actuation when powered thermally. In some embodiments, the thermally-powered polymer fiber tensile actuator can be incorporated into an article, such as a textile or garment.
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公开(公告)号:US20230040112A1
公开(公告)日:2023-02-09
申请号:US17968021
申请日:2022-10-18
Inventor: Michael P. KILGARD , Navzer ENGINEER , David PIERCE
Abstract: A method (of treating a patient who has tinnitus) includes: providing to the patient a series of tones including at least a single tone which is at least a half-octave outside a tinnitus frequency of the patient; and applying vagus nerve stimulation to the patient to induce a period of plasticity in a cortex of the patient that is transitory and that represents a transitory opportunity for learning to occur; and wherein the at least a single tone occurs during the transitory opportunity for learning.
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公开(公告)号:US11471330B2
公开(公告)日:2022-10-18
申请号:US15422958
申请日:2017-02-02
Inventor: Michael P. Kilgard , Navzer Engineer , David Michael Pierce
Abstract: A method of treating tinnitus comprising measuring a patient's hearing, determining the patient's hearing loss and the patient's tinnitus frequency using the measurements of the patient's hearing, programming a clinical controller with the measurements of the patient's hearing, selecting a plurality of therapeutic tones, where the therapeutic tones are selected to be at least a half-octave above or below of the patient's tinnitus frequency, setting an appropriate volume for each of the plurality of tones, repetitively playing each of the plurality of therapeutic tones, and pairing a vagus nerve stimulation pulse train with each playing of a therapeutic tone, thereby reducing the patient's perception of tinnitus.
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公开(公告)号:US20220172610A1
公开(公告)日:2022-06-02
申请号:US17602438
申请日:2020-04-08
Inventor: Zachary Balcar , Ayetullah Baha Biten , Sara Ahmed , Samer Dessouky , Jerome Helffrich
Abstract: The present disclosure relates to systems and methods for passive infrared sensing and detection of vehicular traffic. Vehicle parameters are detected using thermal detection states of pixels of an infrared array sensor. The vehicle parameters can include a velocity of a vehicle. A vehicle record that includes the vehicle parameters can be provided, for example, by a computing device in connection with the infrared array sensor.
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公开(公告)号:US20220140753A1
公开(公告)日:2022-05-05
申请号:US17520523
申请日:2021-11-05
Inventor: Mohammed Jasim Uddin , Abu Musa Abdullah , Alejandro Flores
IPC: H02N1/04 , H04B1/3888
Abstract: A power and/or electricity generating source and/or component that is TENG-based, and that may be configured as an assembly and/or component for powering one or more electronic devices, is disclosed, A case, carrier or other carrying container, for example a case for a cell phone, ipad, electronic tablet, personal computer, or any similar device, that provides an electricity source to power the cell phone, ipad, electronic tablet, is disclosed. The energy generating carriers and/or containers and configurations thereof, also provide an electricity energy storage source. This electronic energy storage source may be incorporated within an electronic device itself, or may be incorporated within the case and/or covering. Upon walking or touching a surface of an electronic device, the power generating source will harness mechanical energy, and provide for the generation of electricity with the one or more TENG components (TESTEC) that comprise the energy generating unit. Metal particles (silver, copper, etc. nanoparticles) incorporated within and/or on polymeric layers and/or a film of the carrier and/or container assembly, are also provided, and provide for enhanced energy generating capacity of the energy generating and storage components described.
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公开(公告)号:US11317515B2
公开(公告)日:2022-04-26
申请号:US15695828
申请日:2017-09-05
Inventor: David Espalin , Ryan Wicker , Alfonso Fernandez , Jorge Ramirez , Jose Motta
Abstract: A method for embedding a line in a substrate. A line embedding head in positioned relative to a surface of the substrate. The line from an output port in the line embedding head is output at an angle relative to the embedding head such that the line is embedded in the substrate.
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公开(公告)号:US11230591B2
公开(公告)日:2022-01-25
申请号:US16094624
申请日:2017-04-18
Inventor: Tong-Ming Fu , Aimin Tang , Dai Wang , Zhiqiang An , Ningyan Zhang , Sha Ha
Abstract: The present invention is directed to antigen binding proteins including, but not limited to, monoclonal antibodies and antigen binding fragments thereof, that specifically bind to and preferably neutralize human cytomegalovirus (CMV). The antigen binding proteins of the invention are useful as a prophylactic and/or therapeutic agent for preventing and/or treating CMV infections in a patient in need thereof. Also encompassed by the invention are pharmaceutical compositions comprising the antigen binding proteins of the invention and a pharmaceutically acceptable carrier. The invention further relates to methods of using the antigen binding proteins and pharmaceutical compositions of the invention for the prevention or treatment of CMV infection in patients in need thereof.
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公开(公告)号:US11116933B2
公开(公告)日:2021-09-14
申请号:US15496766
申请日:2017-04-25
Inventor: Michael P. Kilgard , Larry Cauller , Navzer Engineer , Christa McIntyre Rodriguez , Will Rosellini
Abstract: Systems, methods and devices for paired training include timing controls so that training and neural stimulation can be provided simultaneously. Paired trainings may include therapies, rehabilitation and performance enhancement training. Stimulations of nerves such as the vagus nerve that affect subcortical regions such as the nucleus basalis, locus coeruleus or amygdala induce plasticity in the brain, enhancing the effects of a variety of therapies, such as those used to treat tinnitus, stroke, traumatic brain injury and post-traumatic stress disorder.
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公开(公告)号:US10722573B2
公开(公告)日:2020-07-28
申请号:US15355530
申请日:2016-11-18
Inventor: Burton Dickey , Michael Tuvim , Scott Evans
Abstract: Embodiments of the invention are directed to methods of treating, inhibiting or attenuating a microbial infection in an individual who has or is at risk for developing such an infection, comprising the step of administering an effective amount of a StIR composition to the individual.
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