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公开(公告)号：US20150183747A1
公开(公告)日：2015-07-02
申请号：US14345562
申请日：2012-09-14
申请人： Yu Chen , Lan Yang , Feiyu Feng , Qiufu Ge , Dianwu Guo , Yi Chen
发明人： Yu Chen , Lan Yang , Feiyu Feng , Qiufu Ge , Dianwu Guo , Yi Chen
IPC分类号： C07D235/16 , A61K47/40
CPC分类号： C07D235/16 , A61K9/0019 , A61K9/19 , A61K31/16 , A61K31/4184 , A61K47/40 , A61K47/6951 , Y02A50/414
摘要： The present invention is directed to pharmaceutical compositions comprising: (a) a cyclopolysaccharide and (b) a compound of Formula (I) or its pharmaceutical acceptable salt: wherein X1, X2, Q, Z, and m are defined herein. Also disclosed is a method for treating a neoplastic disease or an immune disease with these compositions.
摘要翻译： 本发明涉及药物组合物，其包含：（a）环多糖和（b）式（I）化合物或其药学上可接受的盐：其中X 1，X 2，Q，Z和m如本文所定义。 还公开了用这些组合物治疗肿瘤疾病或免疫疾病的方法。
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公开(公告)号：US08980909B2
公开(公告)日：2015-03-17
申请号：US13977413
申请日：2012-01-06
IPC分类号： A61K31/44 , A01N43/42 , C07D491/22 , A61K31/4745 , A61K31/496 , A61K31/506 , A61K31/695 , A61K45/06 , C07F7/10
CPC分类号： C07D491/22 , A61K31/4745 , A61K31/496 , A61K31/506 , A61K31/695 , A61K45/06 , C07F7/10 , Y02A50/414
摘要： The disclosure includes hydroxamic compounds of Formula I: (Formula I) wherein Z, L, R1, R2, and R3 are defined herein. Also disclosed is a method for treating a neoplastic disease or an immune disease with these compounds.
摘要翻译： 本公开内容包括式I的异羟肟酸化合物：式（I）其中Z，L，R 1，R 2和R 3在本文中定义。 还公开了用这些化合物治疗肿瘤疾病或免疫疾病的方法。
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公开(公告)号：US08609864B2
公开(公告)日：2013-12-17
申请号：US13143155
申请日：2010-01-07
IPC分类号： A61K31/4184 , C07D235/16
CPC分类号： C07F15/0013 , A61K31/4184 , C07C259/06 , C07D235/16 , C07D235/26 , C07D235/28 , C07D235/30 , C07D239/10 , C07D239/46 , C07D239/47 , C07D405/04 , C07F15/0093 , Y02A50/414
摘要： The disclosure includes hydroxamic compounds of Formula I: (I) wherein P, Z, and m are defined herein. Also disclosed is a method for treating a neoplastic disease or an immune disease with these compounds.
摘要翻译： 本公开内容包括式I的异羟肟酸化合物：（I）其中P，Z和m在本文中定义。 还公开了用这些化合物治疗肿瘤疾病或免疫疾病的方法。
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公开(公告)号：US20130281402A1
公开(公告)日：2013-10-24
申请号：US13977413
申请日：2012-01-06
IPC分类号： C07D491/22 , A61K31/506 , A61K45/06 , A61K31/695 , A61K31/496 , A61K31/4745 , C07F7/10
CPC分类号： C07D491/22 , A61K31/4745 , A61K31/496 , A61K31/506 , A61K31/695 , A61K45/06 , C07F7/10 , Y02A50/414
摘要： The disclosure includes hydroxamic compounds of Formula I: (Formula I) wherein Z, L, R1, R2, and R3 are defined herein. Also disclosed is a method for treating a neoplastic disease or an immune disease with these compounds.
摘要翻译： 本公开内容包括式I的异羟肟酸化合物：式（I）其中Z，L，R 1，R 2和R 3在本文中定义。 还公开了用这些化合物治疗肿瘤疾病或免疫疾病的方法。
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公开(公告)号：US20110269706A1
公开(公告)日：2011-11-03
申请号：US13143155
申请日：2010-01-07
IPC分类号： A61K31/706 , A61K31/7068 , C07H19/12 , C07D239/47 , A61K31/513 , C07D239/553 , C07F9/6584 , A61K31/66 , C07C309/66 , A61K31/255 , C07D235/16 , A61K31/4184 , C07C237/20 , A61K31/165 , C07F15/00 , A61K31/282 , A61K31/555 , A61P35/00 , A61P35/02 , C07H19/06
CPC分类号： C07F15/0013 , A61K31/4184 , C07C259/06 , C07D235/16 , C07D235/26 , C07D235/28 , C07D235/30 , C07D239/10 , C07D239/46 , C07D239/47 , C07D405/04 , C07F15/0093 , Y02A50/414
摘要： The disclosure includes hydroxamic compounds of Formula I: (I) wherein P, Z, and m are defined herein. Also disclosed is a method for treating a neoplastic disease or an immune disease with these compounds.
摘要翻译： 本公开内容包括式I的异羟肟酸化合物：（I）其中P，Z和m在本文中定义。 还公开了用这些化合物治疗肿瘤疾病或免疫疾病的方法。
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公开(公告)号：US09376395B2
公开(公告)日：2016-06-28
申请号：US14345562
申请日：2012-09-14
申请人： Yu Chen , Lan Yang , Feiyu Feng , Qiufu Ge , Dianwu Guo , Yi Chen
发明人： Yu Chen , Lan Yang , Feiyu Feng , Qiufu Ge , Dianwu Guo , Yi Chen
IPC分类号： C07D235/16 , A61K47/40 , A61K31/16 , A61K31/4184 , A61K9/00 , A61K9/19 , A61K47/48
CPC分类号： C07D235/16 , A61K9/0019 , A61K9/19 , A61K31/16 , A61K31/4184 , A61K47/40 , A61K47/6951 , Y02A50/414
摘要： The present invention is directed to pharmaceutical compositions comprising: (a) a cyclopolysaccharide and (b) a compound of Formula (I) or its pharmaceutical acceptable salt: wherein X1, X2, Q, Z, and m are defined herein. Also disclosed is a method for treating a neoplastic disease or an immune disease with these compositions.
摘要翻译： 本发明涉及药物组合物，其包含：（a）环多糖和（b）式（I）化合物或其药学上可接受的盐：其中X 1，X 2，Q，Z和m如本文所定义。 还公开了用这些组合物治疗肿瘤疾病或免疫疾病的方法。
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7.发明授权公开(公告)号：US09568252B2
公开(公告)日：2017-02-14
申请号：US14130169
申请日：2012-06-20
申请人： Mingguang Zheng , Cheng Ye , Xiankang Dong , Guoxing Gu , Jinquan Yan , Yong Wang , Yu Chen , Xia Su , Yu Chen , Liuhua Shen , Libing Zhu , Wei Shi , He Sun
发明人： Mingguang Zheng , Cheng Ye , Xiankang Dong , Guoxing Gu , Jinquan Yan , Yong Wang , Yu Chen , Xia Su , Yu Chen , Liuhua Shen , Libing Zhu , Wei Shi , He Sun
IPC分类号： G21C19/07 , F28D15/02 , G21C19/08 , G21C15/257
CPC分类号： F28D15/02 , F28D15/0266 , G21C15/257 , G21C19/07 , G21C19/08
摘要： A heat pipe based passive residual heat removal system for a spent fuel pool (3). Partitions (6) are arranged around an inside of the spent fuel pool. Evaporation-end heat pipes (4) are arranged between the outside of the partitions and an inner wail of the pool. The evaporation-end heat pipes have outlets that extend beyond the pool and are connected to an Inlet of an ascending pipe (10), and have inlets connected to an outlet of a descending pipe (5). Condensation-end heat pipes (7) have inlets connected to an outlet of the ascending pipe, and have outlets connected to an inlet of the descending pipe. The heat pipes cool the spent fuel pool. A heat exchange by phase change of working medium in the heat pipe leads to heat exchange of low temperature difference and high efficiency, relying on density difference for natural circulation drive.
摘要翻译： 一种用于乏燃料池（3）的基于热管的被动余热除去系统。 分区（6）排列在乏燃料池的内侧。 蒸发端热管（4）布置在隔板的外侧和池的内壁之间。 蒸发端热管具有延伸超出池并且连接到上升管（10）的入口的出口，并且具有连接到下降管（5）的出口的入口。 冷凝端热管（7）具有连接到上升管的出口的入口，并且具有连接到下降管的入口的出口。 热管冷却乏燃料池。 热管中工作介质相变的热交换导致低温差热交换和高效率，依赖于自然循环驱动的密度差。
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公开(公告)号：US10383047B2
公开(公告)日：2019-08-13
申请号：US12298184
申请日：2007-04-17
申请人： Pingping Xing , Zhongji Hu , Yu Chen , Hua Chao
发明人： Pingping Xing , Zhongji Hu , Yu Chen , Hua Chao
摘要： The present invention relates to a method for establishing a service in a first frequency in a communication network, wherein the first frequency does not support the service or supports it in a limited way, the method comprises the following steps: determining the service to be established, re-selecting or redirecting to a second frequency that is suitable for the service, so as to carry out the service in the second frequency. The present invention also relates to user equipment and a network apparatus for establishing a service in a first frequency in a communication network, wherein the first frequency does not support the service or supports it in a limited way. According to the present invention, a non-MBMS service may be established in the MBMS dedicated frequency, so as to carry out the non-MBMS service in the normal frequency.
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公开(公告)号：US09936716B2
公开(公告)日：2018-04-10
申请号：US14944699
申请日：2015-11-18
申请人： Jing Li Chen , Yu Chen
发明人： Jing Li Chen , Yu Chen
CPC分类号： A23B7/015 , A23B7/04 , A23L3/26 , H05B33/0857 , H05B37/029
摘要： A physical method for maintaining the freshness of vegetables and fruits via the technology of the optical signal and optical signal generator are disclosed. By adopting the computer programmable pulsed scanning signal generator, it controls the light-emitting device mounted with red, green and blue light sources group to generate optical signal with pulsed or pulsed periodical scanning combined spectrum. The optical signal irradiates the fresh-cut fruits and vegetables preserved in the storage assembly at room temperature or at controlled temperature and humidity. By regulating the optical signal with periodical pulsed spectrum or pulsed scanning spectrum or periodical pulsed scanning combined spectrum, the irradiated vegetables and fruits obtain photon energy needed in light reactions of photosynthesis from the lighting environment of artificial optical signal which is in bright and dark periodic variation. The metabolism of the cellular tissue is recovered and maintained, and the growth inertia is kept at slow speed. It effectively prolongs the freshness state of vegetables and fruits which are preserved in the storage assembly.
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