公开(公告)号：US20210347767A1

公开(公告)日：2021-11-11

申请号：US16871354

申请日：2020-05-11

申请人： Xingke JU ,  Chengyuan LIANG ,  Yuzhi LIU ,  Bin TIAN ,  Lei TIAN ,  Gennian MAO ,  Limei WANG ,  Yuanyuan HE ,  Yongbo WANG ,  Jingwen XU ,  Dan YANG ,  Liang QI ,  Wenbo YAO ,  Qianqian ZHAO ,  Han LI

发明人： Xingke JU ,  Chengyuan LIANG ,  Yuzhi LIU ,  Bin TIAN ,  Lei TIAN ,  Gennian MAO ,  Limei WANG ,  Yuanyuan HE ,  Yongbo WANG ,  Jingwen XU ,  Dan YANG ,  Liang QI ,  Wenbo YAO ,  Qianqian ZHAO ,  Han LI

IPC分类号： C07D409/14 ,  B01J27/24

摘要： A compound having the formula (I): is disclosed. A method of preparing the compound of formula (I) is also disclosed.

公开(公告)号：US20190389876A1

公开(公告)日：2019-12-26

申请号：US16120403

申请日：2018-09-03

申请人： Bin TIAN ,  Xingke JU ,  Lei TIAN ,  Jie LI ,  Songsong RUAN ,  Minyi JIA ,  Danni TIAN ,  Han LI ,  Qianqian ZHAO ,  Xuechuan WANG ,  Chengyuan LIANG

发明人： Bin TIAN ,  Xingke JU ,  Lei TIAN ,  Jie LI ,  Songsong RUAN ,  Minyi JIA ,  Danni TIAN ,  Han LI ,  Qianqian ZHAO ,  Xuechuan WANG ,  Chengyuan LIANG

IPC分类号： C07D493/04

摘要： A compound having the formula (I): is disclosed. A method of preparing the compound of formula (I) is also disclosed.

公开(公告)号：US20200147042A1

公开(公告)日：2020-05-14

申请号：US16270567

申请日：2019-02-07

申请人： Chengyuan LIANG ,  Lei TIAN ,  Shunjun DING ,  Xingke JU ,  Yuzhi LIU ,  Xiaolin XIE ,  Dezhu ZHANG

发明人： Chengyuan LIANG ,  Lei TIAN ,  Shunjun DING ,  Xingke JU ,  Yuzhi LIU ,  Xiaolin XIE ,  Dezhu ZHANG

IPC分类号： A61K31/404 ,  A61P35/00 ,  G01N33/50

摘要： A gossypol isatin Schiff base compound with antitumor activities represented by formula I: R1 and R2 are independently hydrogen, alkyl, cycloalkyl, alkoxy, nitro, halogen, unsubstituted or substituted phenyl, or unsubstituted or substituted benzyl. A method of preparing the compound of formula I is also disclosed.

公开(公告)号：US20190031840A1

公开(公告)日：2019-01-31

申请号：US16027193

申请日：2018-07-03

申请人： Chengyuan LIANG ,  Lei TIAN ,  Minyi JIA ,  Ying HUANG ,  Xuechuan WANG ,  Taotao QIANG ,  Longfang REN ,  Xingke JU

发明人： Chengyuan LIANG ,  Lei TIAN ,  Minyi JIA ,  Ying HUANG ,  Xuechuan WANG ,  Taotao QIANG ,  Longfang REN ,  Xingke JU

IPC分类号： C08J5/18 ,  G01N33/569 ,  C08L89/06 ,  B65D65/46

CPC分类号： C08J5/18 ,  B65D65/466 ,  C08J2389/06 ,  C08L89/06 ,  C08L2201/06 ,  C08L2201/08 ,  C08L2201/10 ,  C08L2201/14 ,  C08L2203/16 ,  C09H3/00 ,  G01N33/56911 ,  G01N2333/335 ,  G01N2333/4603

摘要： A method of preparing an aesculin sturgeon skin gelatin with antioxidant activity and Enterococcus faecalis detection ability includes: 1) mixing a sturgeon skin gelatin and distilled water in a ratio of 1:15-1:25 (w/v) at 50-70° C. and filtering to obtain a sturgeon skin gelatin solution; 2) adding aesculin and a glycerin solution to the sturgeon skin gelatin solution, stirring the resulted sturgeon skin gelatin solution at 30-50° C. for 30 minutes, and filtering; and 3) removing air bubbles from the sturgeon skin gelatin solution of step 2) under reduced pressure, placing the sturgeon skin gelatin solution on an acrylic glass, and drying the sturgeon skin gelatin solution at in a vented oven 25° C. and 45-55% relative humidity for 24 hours to obtain the aesculin sturgeon skin gelatin film.

公开(公告)号：US20180186776A1

公开(公告)日：2018-07-05

申请号：US15719924

申请日：2017-09-29

申请人： Chengyuan LIANG ,  Minyi JIA ,  Yuecheng LYU ,  Xingke JU ,  Lei TIAN

发明人： Chengyuan LIANG ,  Minyi JIA ,  Yuecheng LYU ,  Xingke JU ,  Lei TIAN

IPC分类号： C07D405/12

CPC分类号： C07D405/12

摘要： A hesperetin aza-cinnamic acid derivative has the following formula (I): R1 is H or alkyl, and R2 and R2 are independently H, alkyl, hydroxy, halogen, nitro, or alkoxy.

公开(公告)号：US20180093966A1

公开(公告)日：2018-04-05

申请号：US15713934

申请日：2017-09-25

申请人： Chengyuan LIANG ,  Xingke JU ,  Lei TIAN ,  Minyi JIA ,  Danni TIAN ,  Shunjun DING

发明人： Chengyuan LIANG ,  Xingke JU ,  Lei TIAN ,  Minyi JIA ,  Danni TIAN ,  Shunjun DING

IPC分类号： C07D401/12

CPC分类号： C07D401/12

摘要： A lappaconitine aza-cinnamic acid derivative having the following formula (I): X is C or N, and R1, R2, and R3 are independently H or lower alkyl. A method of preparing the lappaconitine aza-cinnamic acid derivative of formula (I) is also disclosed.

公开(公告)号：US20220160805A1

公开(公告)日：2022-05-26

申请号：US17173622

申请日：2021-02-11

申请人： Dan YANG ,  Jingyi LI ,  Liang XIN ,  Chunyang SHI ,  Xiaolin XIE ,  Dezhu ZHANG ,  Ruina BIAN ,  Xingke JU ,  Chengyuan LIANG ,  Yanjun LI ,  Qiao ZENG

发明人： Dan YANG ,  Jingyi LI ,  Liang XIN ,  Chunyang SHI ,  Xiaolin XIE ,  Dezhu ZHANG ,  Ruina BIAN ,  Xingke JU ,  Chengyuan LIANG ,  Yanjun LI ,  Qiao ZENG

IPC分类号： A61K36/63 ,  A61K31/7034 ,  A61K31/7048 ,  A61K47/44 ,  A61P31/04

摘要： A Syringa microphylla seed extract includes the following components by weight based on a total weight of the Syringa microphylla seed extract: 0.4944-0.7142 mg/g of echinacoside, 6.624-7.617 mg/g of oleuropein, 0.4276-0.6309 mg/g of verbascoside, 3.927-4.684 mg/g of syringin, and 4.505-5.250 mg/g of forsythiaside B. A method of preparing the Syringa microphylla seed extract is disclosed. A composition for treating antibiotic-resistant infections that includes the Syringa microphylla seed extract is also disclosed.