公开(公告)号：US09874240B2

公开(公告)日：2018-01-23

申请号：US14127615

申请日：2012-06-19

申请人： Wolfgang Fiedler ,  Thomas Lippert ,  Taylan Toprak

发明人： Wolfgang Fiedler ,  Thomas Lippert ,  Taylan Toprak

IPC分类号： F16C7/02 ,  F16C3/02

CPC分类号： F16C7/026 ,  F16C3/026 ,  Y10T29/49945 ,  Y10T74/2142

摘要： The invention relates to a component for absorbing and/or transmitting mechanical forces and/or moments, comprising at least one dimensionally stable component element (12, 12′, 12″, 2′″, 12″″), which has at least one hollow-profiled section (14), and at least one hollow-profiled component element (16) consisting of fiber-reinforced plastic, which can be partially received by the hollow-profiled section (14) of the dimensionally stable component element (12, 12′, 12″, 12′″, 12″″), and can be arranged in a form-fitting manner in the hollow-profiled section (14) of the dimensionally stable component element (12, 12′, 12″, 12′″, 12″″) by means of raised portions (32, 32′) which extend radially inwards and/or depressions (38, 38′), recesses or holes which extend radially outwards, wherein the inner circumference (24) of the hollow-profiled section (14) of the dimensionally stable component element (12, 12′, 12″, 12′″, 12″″) and the outer circumference (26) of the hollow-profiled component element (16) consisting of fiber-reinforced plastic correspond to each other or at least substantially correspond to each other. The invention further relates to a method for the production thereof and the use thereof.

公开(公告)号：US20140137700A1

公开(公告)日：2014-05-22

申请号：US14127615

申请日：2012-06-19

申请人： Wolfgang Fiedler ,  Thomas Lippert ,  Taylan Toprak

发明人： Wolfgang Fiedler ,  Thomas Lippert ,  Taylan Toprak

IPC分类号： F16C7/02

CPC分类号： F16C7/026 ,  F16C3/026 ,  Y10T29/49945 ,  Y10T74/2142

摘要： The invention relates to a component for absorbing and/or transmitting mechanical forces and/or moments, comprising at least one dimensionally stable component element (12, 12′, 12″, 2″′, 12″″), which has at least one hollow-profiled section (14), and at least one hollow-profiled component element (16) consisting of fibre-reinforced plastic, which can be partially received by the hollow-profiled section (14) of the dimensionally stable component element (12, 12′, 12″, 12″′, 12″″), and can be arranged in a form-fitting manner in the hollow-profiled section (14) of the dimensionally stable component element (12, 12′, 12″, 12″′, 12″″) by means of raised portions (32, 32′) which extend radially inwards and/or depressions (38, 38′), recesses or holes which extend radially outwards, wherein the inner circumference (24) of the hollow-profiled section (14) of the dimensionally stable component element (12, 12′, 12″, 12″′, 12″″) and the outer circumference (26) of the hollow-profiled component element (16) consisting of fibre-reinforced plastic correspond to each other or at least substantially correspond to each other. The invention further relates to a method for the production thereof and the use thereof.

摘要翻译： 本发明涉及用于吸收和/或传递机械力和/或力矩的部件，其包括至少一个尺寸稳定的部件元件（12,12'，12“，”2“'，12”“），其具有至少一个 空心型材部分（14）和由纤维增强塑料组成的至少一个中空型元件（16），其可由尺寸稳定的元件（12）的中空型材部分（14）部分地接收， 12“，12”，12“'，12”“），并且可以以形状配合的方式布置在尺寸稳定的部件（12,12'，12”，12“，12”，12“ “，12”“）通过径向向内和/或凹陷（38,38'）延伸的凸起部分（32,32'），径向向外延伸的凹部或孔，其中， 尺寸稳定的元件（12,12'，12“，12”'，12“”）的空心型材部分（14） 由纤维增强塑料构成的中空型构件（16）的圆周（26）彼此对应或至少基本对应。 本发明还涉及其生产方法及其用途。

公开(公告)号：US07794654B2

公开(公告)日：2010-09-14

申请号：US11620931

申请日：2007-01-08

申请人： Karin Schwind ,  Wolfgang Fiedler

发明人： Karin Schwind ,  Wolfgang Fiedler

IPC分类号： C12Q1/68

CPC分类号： A61L2/087 ,  A61B5/1486 ,  A61B5/150022 ,  A61B5/150282 ,  A61B5/150335 ,  A61B5/150358 ,  A61B5/150412 ,  A61B5/15045 ,  A61B5/150503 ,  A61B5/150541 ,  A61B5/150572 ,  A61B5/150633 ,  A61B5/150702 ,  A61B5/150717 ,  A61B5/1513 ,  A61B5/15194 ,  A61B2010/0003 ,  A61B2090/0813 ,  A61L2202/22

摘要： The invention concerns a method for producing integrated, diagnostic test elements (1) which have a lancing area (2) and a detection area (3). The lancing area is used to generate an opening in the skin and the detection area is used to detect an analyte in a body fluid. The selective sterilization sterilizes the lancing area but not the detection area by electron radiation. The method according to the invention comprises the steps of screening the detection area on the test element against electron radiation and subsequently irradiating the test element with electron radiation. The invention additionally concerns a method according to the invention in which the test elements and lancing areas are in a connected arrangement and are brought into the radiation area by moving the entire arrangement. Finally the invention concerns a diagnostic test element which has been produced according to the inventive method.

摘要翻译： 本发明涉及一种用于生成具有穿刺区域（2）和检测区域（3）的综合诊断测试元件（1）的方法。 穿刺区域用于在皮肤中产生开口，并且检测区域用于检测体液中的分析物。 通过电子辐射，选择性消毒对穿刺区域进行消毒，而不是检测区域。 根据本发明的方法包括以下步骤：针对电子辐射筛选测试元件上的检测区域，随后用电子辐射照射测试元件。 本发明还涉及根据本发明的方法，其中测试元件和穿刺区域处于连接的布置并且通过移动整个布置而被带入辐射区域。 最后，本发明涉及根据本发明方法生产的诊断测试元件。

公开(公告)号：US07527740B2

公开(公告)日：2009-05-05

申请号：US10492256

申请日：2002-09-14

申请人： Carlo Effenhauser ,  Gregor Ocvirk ,  Wolfgang Fiedler

发明人： Carlo Effenhauser ,  Gregor Ocvirk ,  Wolfgang Fiedler

IPC分类号： B01D37/00 ,  B01D11/00

CPC分类号： G01N15/05 ,  A61M1/3693 ,  B01L3/502753 ,  B01L2200/0647 ,  B01L2300/0816 ,  G01N33/491 ,  G01N2015/055 ,  G01N2015/1486 ,  Y10T436/25 ,  Y10T436/25375

摘要： A method for separating particles from a fluid dispersion, particularly for separating corpuscular components from biological samples, above all from blood. A separating module suitable for performing the method has a substrate with flow channels, comprising a feed channel for supplying the dispersion to a junction, a first drain channel for draining fluid having a reduced particle concentration away from the junction, and a second drain channel for draining fluid having an increased particle concentration away from the junction. The fluid flows so much faster in the second drain channel than in the first drain channel that due to the different flow speeds the dispersed particles preferentially flow at the junction further in the second drain channel.

摘要翻译： 一种用于从流体分散体中分离颗粒的方法，特别是用于从生物样品中分离出红细胞成分，尤其是血液。 适于执行该方法的分离模块具有带有流动通道的基底，包括用于将分散体供应到结点的进料通道，用于排出离开结点的具有降低的粒子浓度的流体的第一排出通道和用于 具有离开结点的具有增加的颗粒浓度的排出流体。 在第二排水通道中流体流动比在第一排水通道中要快得多，由于不同的流速，分散的颗粒优先在第二排水通道中的结点处流动。

公开(公告)号：US07582794B2

公开(公告)日：2009-09-01

申请号：US11755071

申请日：2007-05-30

申请人： Wolfgang Fiedler ,  Bernd Neises ,  Jochen Hachtel

发明人： Wolfgang Fiedler ,  Bernd Neises ,  Jochen Hachtel

IPC分类号： C07C65/01

CPC分类号： C07D263/32 ,  C07C51/367 ,  C07C65/24

摘要： The invention relates to a process for the preparation of a compound of the general formula (I) in which a) a compound (II) is reacted in the presence of a base B1 with a compound (III) and b) the compound (IV) formed as intermediate in step a) is reacted in the presence of a base B2 with a compound (V) to give the compound of the general formula (I)

摘要翻译： 本发明涉及一种制备通式（I）化合物的方法，其中a）使化合物（II）在碱B1存在下与化合物（III）反应，和b）化合物（IV） ）在碱B2的存在下与化合物（V）反应，得到通式（I）的化合物，

公开(公告)号：US20070176120A1

公开(公告)日：2007-08-02

申请号：US11620931

申请日：2007-01-08

申请人： Karin Schwind ,  Wolfgang Fiedler

发明人： Karin Schwind ,  Wolfgang Fiedler

IPC分类号： G21G5/00 ,  A61B5/00

CPC分类号： A61L2/087 ,  A61B5/1486 ,  A61B5/150022 ,  A61B5/150282 ,  A61B5/150335 ,  A61B5/150358 ,  A61B5/150412 ,  A61B5/15045 ,  A61B5/150503 ,  A61B5/150541 ,  A61B5/150572 ,  A61B5/150633 ,  A61B5/150702 ,  A61B5/150717 ,  A61B5/1513 ,  A61B5/15194 ,  A61B2010/0003 ,  A61B2090/0813 ,  A61L2202/22

摘要： The invention concerns a method for producing integrated, diagnostic test elements (1) which have a lancing area (2) and a detection area (3). The lancing area is used to generate an opening in the skin and the detection area is used to detect an analyte in a body fluid. The selective sterilization sterilizes the lancing area but not the detection area by electron radiation. The method according to the invention comprises the steps of screening the detection area on the test element against electron radiation and subsequently irradiating the test element with electron radiation. The invention additionally concerns a method according to the invention in which the test elements and lancing areas are in a connected arrangement and are brought into the radiation area by moving the entire arrangement. Finally the invention concerns a diagnostic test element which has been produced according to the inventive method.

摘要翻译： 本发明涉及一种用于生成具有穿刺区域（2）和检测区域（3）的综合诊断测试元件（1）的方法。 穿刺区域用于在皮肤中产生开口，并且检测区域用于检测体液中的分析物。 通过电子辐射，选择性消毒对穿刺区域进行消毒，而不是检测区域。 根据本发明的方法包括以下步骤：针对电子辐射筛选测试元件上的检测区域，随后用电子辐射照射测试元件。 本发明还涉及根据本发明的方法，其中测试元件和穿刺区域处于连接的布置并且通过移动整个布置而被带入辐射区域。 最后，本发明涉及根据本发明方法生产的诊断测试元件。

公开(公告)号：US20110036153A1

公开(公告)日：2011-02-17

申请号：US12912547

申请日：2010-10-26

申请人： Gregor Ocvirk ,  Peter Kraemer ,  Wolfgang Fiedler

发明人： Gregor Ocvirk ,  Peter Kraemer ,  Wolfgang Fiedler

IPC分类号： G01N1/00

CPC分类号： B01L3/50273 ,  B01L2300/0809 ,  B01L2300/0825 ,  B01L2300/0877 ,  B01L2300/0887 ,  B01L2300/123 ,  B01L2300/161 ,  B01L2400/0406 ,  B01L2400/0415

摘要： The invention relates to a test element for the testing of a liquid sample. The test element includes a sample application area, a test field, a sample transport path extending between the sample application area and the test field and an actuator field including a electrically-conductive layer. The actuator field is switchable between a first state attracting the sample and a second state attracting the sample less by applying to the conductive layer an electric voltage that is different from an earth potential. The actuator field has a section that is arranged at about the same distance from the sample application area as the test field, measured along the sample transport path, such that a wetting of the test field by the sample can be controlled by applying a voltage to the actuator field.

摘要翻译： 本发明涉及一种用于液体样品测试的测试元件。 测试元件包括样品施加区域，测试场，在样品施加区域和测试场之间延伸的样品传输路径和包括导电层的致动器场。 致动器场可以在吸引样品的第一状态和通过向导电层施加不同于地电势的电压而吸引样品的第二状态之间切换。 致动器场具有沿着样品输送路径测量的与测试场的样品施加区域大致相同距离的部分，从而可以通过施加电压来控制样品的测试场的润湿 执行机构领域。

公开(公告)号：US07842235B2

公开(公告)日：2010-11-30

申请号：US11057524

申请日：2005-02-14

申请人： Gregor Ocvirk ,  Peter Kraemer ,  Wolfgang Fiedler

发明人： Gregor Ocvirk ,  Peter Kraemer ,  Wolfgang Fiedler

IPC分类号： G01N31/22 ,  G01N31/00

CPC分类号： B01L3/50273 ,  B01L2300/0809 ,  B01L2300/0825 ,  B01L2300/0877 ,  B01L2300/0887 ,  B01L2300/123 ,  B01L2300/161 ,  B01L2400/0406 ,  B01L2400/0415

摘要： The invention relates to a test element for the testing of a liquid sample. The test element includes a sample application area, a test field, a sample transport path extending between the sample application area and the test field and an actuator field including an electrically-conductive layer. The actuator field is switchable between a first state attracting the sample and a second state attracting the sample less by applying to the conductive layer an electric voltage that is different from an earth potential. The actuator field has a section that is arranged at about the same distance from the sample application area as the test field, measured along the sample transport path. Such that, a wetting of the test field by the sample can be controlled by applying a voltage to the actuator field.

摘要翻译： 本发明涉及一种用于液体样品测试的测试元件。 测试元件包括样品施加区域，测试区域，在样品施加区域和测试区域之间延伸的样品传输路径和包括导电层的致动器场。 致动器场可以在吸引样品的第一状态和通过向导电层施加不同于地电势的电压而吸引样品的第二状态之间切换。 致动器场具有沿着样品输送路径测量的与测试场的样品施加区域大致相同距离的部分。 这样可以通过向致动器场施加电压来控制样品对测试场的润湿。

公开(公告)号：US20090041624A1

公开(公告)日：2009-02-12

申请号：US11722973

申请日：2005-12-22

申请人： Gernot Hochmuth ,  Gregor Ocvirk ,  Wolfgang Fiedler

发明人： Gernot Hochmuth ,  Gregor Ocvirk ,  Wolfgang Fiedler

IPC分类号： B01J19/00 ,  B32B37/00 ,  B32B38/10 ,  B32B38/06 ,  C23F1/00 ,  B32B38/00

CPC分类号： B29C65/54 ,  B01L3/502707 ,  B01L3/502715 ,  B01L2200/027 ,  B01L2200/0689 ,  B01L2200/12 ,  B01L2300/0816 ,  B01L2300/0838 ,  B01L2300/0887 ,  B29C65/483 ,  B29C65/4845 ,  B29C66/1122 ,  B29C66/1222 ,  B29C66/1224 ,  B29C66/522 ,  B29C66/534 ,  B29C66/71 ,  B29L2031/756 ,  F16L37/025 ,  Y10T156/1043 ,  B29K2023/38 ,  B29K2069/00 ,  B29K2083/00

摘要： A fluidic structure and a method for production of a fluidic structure are provided. The method may comprise, in order, introducing at least one externally accessible opening into at least one base substrate of the fluidic structure, partially introducing at least one section of a fluidic conductor, which has at least one inner lumen and at least one conductor wall, in particular of a tube or flexible tube, into the at least one opening, introducing at least one curable fluid sealing material into the at least one opening, entirely or partially curing the at least one fluid sealing material, and producing at least one connecting channel between at least one inner lumen in the at least one fluidic conductor and at least one fluid channel in the fluidic structure, the at least one connecting channel passing through at least one conductor wall.

摘要翻译： 提供流体结构和流体结构的制造方法。 该方法可以依次包括将至少一个外部可接近的开口引入到流体结构的至少一个基底基底中，部分地引入流体导体的至少一个部分，其具有至少一个内腔和至少一个导体壁 ，特别是管或柔性管，进入所述至少一个开口，将至少一个可固化流体密封材料引入所述至少一个开口中，将所述至少一种流体密封材料全部或部分固化，并且产生至少一个连接 在所述至少一个流体导体中的至少一个内腔和所述流体结构中的至少一个流体通道之间的通道，所述至少一个连接通道穿过至少一个导体壁。

公开(公告)号：US20070219395A1

公开(公告)日：2007-09-20

申请号：US11755071

申请日：2007-05-30

申请人： Wolfgang Fiedler ,  Bernd Neises ,  Jochen Hachtel

发明人： Wolfgang Fiedler ,  Bernd Neises ,  Jochen Hachtel

IPC分类号： C07C59/13

CPC分类号： C07D263/32 ,  C07C51/367 ,  C07C65/24

摘要： The invention relates to a process for the preparation of a compound of the general formula (I) in which a) a compound (II) is reacted in the presence of a base B1 with a compound (III) and b) the compound (IV) formed as intermediate in step a) is reacted in the presence of a base B2 with a compound (V) to give the compound of the general formula (I)

摘要翻译： 本发明涉及一种制备通式（I）化合物的方法，其中a）使化合物（II）在碱B1存在下与化合物（III）反应，和b）化合物（IV） ）在碱B2的存在下与化合物（V）反应，得到通式（I）的化合物，