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    RAPID DETECTION OF CEREBROSPINAL FLUID, METHODS AND SYSTEMS THEREFORE
    1.
    发明申请
    RAPID DETECTION OF CEREBROSPINAL FLUID, METHODS AND SYSTEMS THEREFORE 审中-公开
    快速检测脑脊液，其方法和系统

    公开(公告)号：US20120288959A1

    公开(公告)日：2012-11-15

    申请号：US13377146

    申请日：2010-06-08

    Applicant: Wesley Palmer ,  Michael Lee ,  Richard Young ,  Munisch Gupta

    Inventor： Wesley Palmer ,  Michael Lee ,  Richard Young ,  Munisch Gupta

    IPC: G01N33/566 ,  G01N21/78

    CPC classification number: G01N21/78 ,  G01N33/54366 ,  G01N33/558 ,  G01N2333/4724 ,  G01N2333/79

    Abstract: Methods and systems are disclosed for rapid detection of cerebrospinal fluid (CSF) in a sample. In some embodiments, the methods comprise depleting a biological sample of beta-1 transferrin by contacting the sample with a sialic acid-specific lectin bound to a solid support, followed by subjecting the beta-1 transferrin-depleted sample to a lateral flow immunoassay. The methods can be used to detect CSF comprised by a sample in under one hour. Furthermore, the methods can detect CSF in a biological sample such as a plasma sample of a volume as small as about 10 μl.

    Abstract translation: 公开了用于在样品中快速检测脑脊液（CSF）的方法和系统。 在一些实施方案中，所述方法包括通过使样品与结合到固体支持物的唾液酸特异性凝集素接触，然后使β-1转铁蛋白贫化样品进行侧流免疫测定来消耗β-1转铁蛋白的生物样品。 该方法可用于在1小时内检测由样品组成的CSF。 此外，该方法可以检测生物样品中的CSF，例如体积小至约10μl的血浆样品。

    Automatic Toilet Plunger Device
    2.
    发明申请
    Automatic Toilet Plunger Device 审中-公开

    公开(公告)号：US20200263402A1

    公开(公告)日：2020-08-20

    申请号：US16869046

    申请日：2020-05-07

    Applicant: Michael Lee

    Inventor： Michael Lee

    IPC: E03C1/308

    Abstract: An automatic toilet plunger for clearing a blockage in a toilet includes a pipe having a plunger head engaged to a bottom end thereof so that the plunger head is in fluidic communication with the pipe. A pair of arms is hingedly engaged to the pipe. The arms are selectively positionable in an extended configuration and a stowed configuration. In the extended configuration, the arms engage a seat of a toilet. The arms fold downwardly, toward the bottom end of the pipe, into the stowed configuration. A handle, which is engaged to a top end of the pipe and which extends bilaterally therefrom, is hollow and in fluidic communication with the pipe. An actuator is engaged to at least one of the handle and the pipe and positioned therein. The actuator is manipulated to cause the plunger head to clear a blockage in the toilet.

    Automatic toilet plunger
    3.
    发明授权
    Automatic toilet plunger 有权

    公开(公告)号：US10655312B1

    公开(公告)日：2020-05-19

    申请号：US16184128

    申请日：2018-11-08

    Applicant: Michael Lee

    Inventor： Michael Lee

    IPC: E03C1/308

    Abstract: An automatic toilet plunger includes a plunger body having a top end, a bottom end, and an inside. The plunger body is hollow and cylindrical. A plunger head is coupled to the bottom end of the plunger body. A plunging mechanism is coupled inside the plunger body of the plunger. The plunging mechanism is in operational communication with the plunger head and is configured to cause the plunger head to clear a toilet. A plurality of controls is coupled to the plunger body and is in operational communication with the plunging mechanism. A power source is coupled to the plunger body and is in operational communication with, and provides power to, the plunging mechanism.

    AUTOMATIC TOILET PLUNGER
    4.
    发明申请
    AUTOMATIC TOILET PLUNGER 有权

    公开(公告)号：US20200149257A1

    公开(公告)日：2020-05-14

    申请号：US16184128

    申请日：2018-11-08

    Applicant: Michael Lee

    Inventor： Michael Lee

    IPC: E03C1/308

    Abstract: An automatic toilet plunger includes a plunger body having a top end, a bottom end, and an inside. The plunger body is hollow and cylindrical. A plunger head is coupled to the bottom end of the plunger body. A plunging mechanism is coupled inside the plunger body of the plunger. The plunging mechanism is in operational communication with the plunger head and is configured to cause the plunger head to clear a toilet. A plurality of controls is coupled to the plunger body and is in operational communication with the plunging mechanism. A power source is coupled to the plunger body and is in operational communication with, and provides power to, the plunging mechanism.

    Rotor assembly and reversible turbine blade retainer therefor
    8.
    发明授权
    Rotor assembly and reversible turbine blade retainer therefor 有权
    转子组件和可逆涡轮叶片保持器

    公开(公告)号：US08727735B2

    公开(公告)日：2014-05-20

    申请号：US13173575

    申请日：2011-06-30

    Applicant: Michael Lee ,  David Coburn ,  Joseph Fagan

    Inventor： Michael Lee ,  David Coburn ,  Joseph Fagan

    IPC: F01D5/32

    CPC classification number: F01D5/3015 ,  F05D2240/40 ,  F05D2250/33 ,  Y02T50/671

    Abstract: A blade retainer for a gas turbine engine includes a plate-like member with an arcuate outer face, an opposed inner face, and two spaced-apart end faces. The member has an outer portion disposed adjacent the outer face, and an inner portion disposed adjacent the inner face, and a wedge-shaped recess with a concave radiused valley is formed in the inner portion adjacent each end face. The retainer is left-right symmetrical.

    Abstract translation: 用于燃气涡轮发动机的叶片保持器包括具有弓形外表面，相对的内表面和两个间隔开的端面的板状构件。 所述构件具有邻近所述外表面设置的外部部分和邻近所述内表面设置的内部部分，并且在与所述每个端面相邻的所述内部部分中形成具有凹形弧形谷部的楔形凹部。 保持架是左右对称的。

    DETERMINATION OF A MAGNETIC RESONANCE IMAGING PULSE SEQUENCE PROTOCOL CLASSIFICATION
    9.
    发明申请
    DETERMINATION OF A MAGNETIC RESONANCE IMAGING PULSE SEQUENCE PROTOCOL CLASSIFICATION 有权
    磁共振成像脉冲序列协议分类的确定

    公开(公告)号：US20130338930A1

    公开(公告)日：2013-12-19

    申请号：US14002206

    申请日：2012-02-21

    Applicant: Julien Senegas ,  Stefanie Remmele ,  Michael Lee

    Inventor： Julien Senegas ,  Stefanie Remmele ,  Michael Lee

    IPC: G01R33/54 ,  G06F19/00

    CPC classification number: G01R33/54 ,  G01R33/543 ,  G01R33/546 ,  G01R33/5608 ,  G06F11/327 ,  G06F19/00 ,  G06F19/321 ,  G06F19/34 ,  G16H40/63

    Abstract: A medical imaging device (300) comprising a magnetic resonance imaging system (302). The medical image device further comprises a memory (334) containing machine executable instructions (370, 372, 374, 376, 378, 380, 382, 384, 386) for execution by a processor (328). Execution of the instructions causes the processor to receive (100, 204) a pulse sequence protocol (340). Execution of the instructions further causes the processor to determine (102, 206) a pulse sequence type classification (342) descriptive of the pulse sequence protocol. Execution of the instructions further cause the processor to determine (104, 208) a magnetic resonance contrast classification (344), wherein the choice of the magnetic resonance contrast classification depends upon the pulse sequence type classification. Execution of the instructions further causes the processor to determine (106, 210) a pulse sequence protocol classification (346). The pulse sequence protocol classification is determined by the pulse sequence type classification and the magnetic resonance contrast classification.

    Abstract translation: 一种包括磁共振成像系统（302）的医学成像装置（300）。 医学图像设备还包括用于由处理器（328）执行的机器可执行指令（370,372,374,376,378,380,382,384,386）的存储器（334）。 执行指令使得处理器接收（100,204）脉冲序列协议（340）。 执行指令还使处理器确定（102,206）描述脉冲序列协议的脉冲序列类型分类（342）。 执行指令还使得处理器确定（104,208）磁共振对比度分类（344），其中磁共振对比度分类的选择取决于脉冲序列类型分类。 执行指令还使处理器确定（106,210）脉冲序列协议分类（346）。 脉冲序列协议分类由脉冲序列类型分类和磁共振对比分类决定。

    Method and system for microfluidic device and imaging thereof
    10.
    发明授权
    Method and system for microfluidic device and imaging thereof 有权
    微流体装置及其成像方法及系统

    公开(公告)号：US08367016B2

    公开(公告)日：2013-02-05

    申请号：US13360591

    申请日：2012-01-27

    Applicant: Emerson Chueng Quan ,  Colin Jon Taylor ,  Michael Lee ,  Christopher G. Ceasar ,  Greg Harris ,  Gang Sun

    Inventor： Emerson Chueng Quan ,  Colin Jon Taylor ,  Michael Lee ,  Christopher G. Ceasar ,  Greg Harris ,  Gang Sun

    IPC: G01N33/00

    CPC classification number: G01N33/00 ,  B01L3/5025 ,  B01L3/502707 ,  B01L2200/025 ,  B01L2200/12 ,  B01L2300/0816 ,  B01L2300/0864 ,  B01L2300/0867 ,  B01L2300/087 ,  B01L2300/0887 ,  B01L2400/0481 ,  B01L2400/0655 ,  Y10T436/11

    Abstract: A method for producing an image of an object within a chamber of a microfluidic device includes providing the microfluidic device having x, y, and z dimensions and a chamber depth center point located along the z dimension. The chamber depth center point is located a known z dimension distance from a fiducial marking embedded within the microfluidic device. The method also includes placing the microfluidic device within an imaging system that includes an optical device capable of detecting the fiducial marking. The optical device defines an optical path axially aligned with the z dimension and has a focal plane perpendicular to the optical path. When the focal plane is moved along the optical path, the fiducial marking is maximally detected when the focal plane is at the z depth in comparison to when the focal plane is not substantially in-plane with the z depth.

    Abstract translation: 用于在微流体装置的腔室内产生物体的图像的方法包括提供具有x，y和z尺寸的微流体装置以及沿着z维度定位的腔室中心点。 腔室深度中心点位于与嵌入在微流体装置内的基准标记的已知z维距离。 该方法还包括将微流体装置放置在包括能够检测基准标记的光学装置的成像系统内。 光学装置限定与z尺寸轴向对准的光路，并且具有垂直于光路的焦平面。 当焦平面沿着光路移动时，当焦平面与z深度基本上不在平面内时，当焦平面处于z深度时，基准标记被最大程度地检测。

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