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公开(公告)号：US09005972B2
公开(公告)日：2015-04-14
申请号：US14185090
申请日：2014-02-20
Applicant: Wake Forest University Health Sciences
Inventor： Tao Xu , James J. Yoo , Anthony Atala , Dennis Dice
IPC: A61K9/00 , B41M5/52 , B41M99/00 , C12N11/04 , A61K35/36 , A61L27/38 , A61L27/50 , A61L27/58 , B41J3/407 , C12N11/08 , D01D5/00 , D01F6/62 , A61K35/32 , A61K35/34 , A61F2/06
CPC classification number: A61K9/5089 , A61F2/062 , A61K35/32 , A61K35/34 , A61K35/36 , A61L27/38 , A61L27/50 , A61L27/58 , B33Y80/00 , B41J3/407 , C12N5/0655 , C12N11/04 , C12N11/08 , C12N2533/54 , C12N2533/56 , D01D5/0007 , D01F6/625
Abstract: Provided herein is an apparatus for printing cells which includes an electrospinning device and an inkjet printing device operatively associated therewith. Methods of making a biodegradable scaffold having cells seeded therein are also provided. Methods of forming microparticles containing one or more cells encapsulated by a substrate are also provided, as are methods of forming an array of said microparticles.
Abstract translation: 本文提供了一种用于印刷电池的装置，其包括静电纺丝装置和与其可操作地相关联的喷墨打印装置。 还提供了制备具有种子细胞的可生物降解的支架的方法。 还提供了形成包含一个或多个由基底包封的细胞的微粒的方法，以及形成所述微粒阵列的方法。
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公开(公告)号：US20200238024A1
公开(公告)日：2020-07-30
申请号：US16696738
申请日：2019-11-26
Applicant: Wake Forest University Health Sciences
Inventor： James J. Yoo , Anthony Atala , Kyle W. Binder , Mohammad Z. Albanna , Weixin Zhao , Dennis Dice , Tao Xu
IPC: A61M11/00 , A61B5/00 , A61B5/107 , A61L27/22 , A61L27/24 , A61L27/38 , A61L27/60 , C12N5/077 , A61M35/00
Abstract: Provided herein is a delivery system, including: (a) an optical sensor configured to detect data to create a map of a patient bodily surface; and (b) a dispenser operatively associated with the optical sensor and configured to deliver compositions (optionally including cells) to the patient bodily surface based upon the data or map. Methods of forming a tissue on a patient bodily surface of a patient in need thereof are also provided, as are methods, systems and computer program products useful for processing patient bodily surface data.
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公开(公告)号：US20190153382A1
公开(公告)日：2019-05-23
申请号：US16227690
申请日：2018-12-20
Applicant: WAKE FOREST UNIVERSITY HEALTH SCIENCES
Inventor： James Yoo , Tao Xu , Anthony Atala
Abstract: A method of forming an array of viable cells is carried out by ink-jet printing a cellular composition containing said cells on a substrate. At least two different types of viable mammalian cells are printed on the substrate, the at least two different types of viable mammalian cells selected to together form a tissue. In some embodiments at least three or four different viable mammalian cells are printed on the substrate, the cells selected to together form a tissue. In some embodiments one of the viable mammalian cell types is a stem cell. In some embodiments the method further comprises printing at least one support compound on the substrate, the support compound selected to form a tissue together with said cells. In some embodiments the method further comprises printing at least one growth factor on the substrate, the growth factor selected to cause the cells to form a tissue.
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公开(公告)号：US20190038849A1
公开(公告)日：2019-02-07
申请号：US16158808
申请日：2018-10-12
Applicant: Wake Forest University Health Sciences
Inventor： James J. Yoo , Anthony Atala , Kyle W. Binder , Mohammad Z. Albanna , Weixin Zhao , Dennis Dice , Tao Xu
IPC: A61M11/00 , A61L27/38 , A61L27/60 , A61B5/00 , A61B5/107 , A61L27/22 , C12N5/077 , A61M35/00 , A61L27/24 , A61B34/30 , A61B90/50 , A61B17/00 , A61B17/322 , A61B34/10 , B41J3/407
Abstract: Provided herein is a delivery system, including: (a) an optical sensor configured to detect data to create a map of a patient bodily surface; and (b) a dispenser operatively associated with the optical sensor and configured to deliver compositions (optionally including cells) to the patient bodily surface based upon the data or map. Methods of forming a tissue on a patient bodily surface of a patient in need thereof are also provided, as are methods, systems and computer program products useful for processing patient bodily surface data.
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公开(公告)号：US20230372637A1
公开(公告)日：2023-11-23
申请号：US18364567
申请日：2023-08-03
Applicant: Wake Forest University Health Sciences
Inventor： James J. Yoo , Anthony Atala , Kyle W. Binder , Mohammad Z. Albanna , Weixin Zhao , Dennis Dice , Tao Xu
IPC: A61M11/00 , A61B5/00 , A61B5/107 , A61L27/22 , A61L27/24 , A61L27/38 , A61L27/60 , C12N5/077 , A61M35/00
CPC classification number: A61M11/00 , A61B5/6835 , A61B5/1077 , A61B5/1079 , A61B5/445 , A61B5/0064 , A61L27/225 , A61L27/24 , A61L27/3813 , A61L27/60 , C12N5/0656 , A61M35/20 , B41J3/4073
Abstract: Provided herein is a delivery system, including: (a) an optical sensor configured to detect data to create a map of a patient bodily surface; and (b) a dispenser operatively associated with the optical sensor and configured to deliver compositions (optionally including cells) to the patient bodily surface based upon the data or map. Methods of forming a tissue on a patient bodily surface of a patient in need thereof are also provided, as are methods, systems and computer program products useful for processing patient bodily surface data.
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Patent Agency Ranking
公开(公告)号：US10537689B2
公开(公告)日：2020-01-21
申请号：US16158808
申请日：2018-10-12
Applicant: Wake Forest University Health Sciences
Inventor： James J. Yoo , Anthony Atala , Kyle W. Binder , Mohammad Z. Albanna , Weixin Zhao , Dennis Dice , Tao Xu
IPC: A61M5/178 , A61M11/00 , A61B5/00 , A61B5/107 , A61M35/00 , A61L27/22 , A61L27/24 , A61L27/38 , A61L27/60 , C12N5/077 , A61M1/00 , A61M5/00 , A61M5/315 , A61M27/00 , B41J3/407 , A61B17/00 , A61B17/322 , A61B90/50 , A61B34/30 , A61B34/10
Abstract: Provided herein is a delivery system, including: (a) an optical sensor configured to detect data to create a map of a patient bodily surface; and (b) a dispenser operatively associated with the optical sensor and configured to deliver compositions (optionally including cells) to the patient bodily surface based upon the data or map. Methods of forming a tissue on a patient bodily surface of a patient in need thereof are also provided, as are methods, systems and computer program products useful for processing patient bodily surface data.
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公开(公告)号：US10118005B2
公开(公告)日：2018-11-06
申请号：US14019714
申请日：2013-09-06
Applicant: Wake Forest University Health Sciences
Inventor： James J. Yoo , Anthony Atala , Kyle W. Binder , Mohammad Z. Albanna , Weixin Zhao , Dennis Dice , Tao Xu
IPC: A61M11/00 , A61B5/00 , A61B5/107 , A61M35/00 , A61L27/22 , A61L27/24 , A61L27/38 , A61L27/60 , C12N5/077 , B41J3/407 , A61B17/00 , A61B17/322 , A61B90/50 , A61B34/30 , A61B34/10
Abstract: Provided herein is a delivery system, including: (a) an optical sensor configured to detect data to create a map of a patient bodily surface; and (b) a dispenser operatively associated with the optical sensor and configured to deliver compositions (optionally including cells) to the patient bodily surface based upon the data or map. Methods of forming a tissue on a patient bodily surface of a patient in need thereof are also provided, as are methods, systems and computer program products useful for processing patient bodily surface data.
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公开(公告)号：US09301925B2
公开(公告)日：2016-04-05
申请号：US14644678
申请日：2015-03-11
Applicant: Wake Forest University Health Sciences
Inventor： Tao Xu , James J. Yoo , Anthony Atala
IPC: C12N5/02 , C12N11/04 , A61K9/50 , A61L27/38 , A61L27/50 , A61L27/58 , B41J3/407 , C12N11/08 , D01D5/00 , D01F6/62 , A61K35/32 , A61K35/34 , A61K35/36 , A61F2/06
CPC classification number: A61K9/5089 , A61F2/062 , A61K35/32 , A61K35/34 , A61K35/36 , A61L27/38 , A61L27/50 , A61L27/58 , B33Y80/00 , B41J3/407 , C12N5/0655 , C12N11/04 , C12N11/08 , C12N2533/54 , C12N2533/56 , D01D5/0007 , D01F6/625
Abstract: Provided herein is an apparatus for printing cells which includes an electrospinning device and an inkjet printing device operatively associated therewith. Methods of making a biodegradable scaffold having cells seeded therein are also provided. Methods of forming microparticles containing one or more cells encapsulated by a substrate are also provided, as are methods of forming an array of said microparticles.
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公开(公告)号：US20150182471A1
公开(公告)日：2015-07-02
申请号：US14644678
申请日：2015-03-11
Applicant: Wake Forest University Health Sciences
Inventor： Tao Xu , James J. Yoo , Anthony Atala
CPC classification number: A61K9/5089 , A61F2/062 , A61K35/32 , A61K35/34 , A61K35/36 , A61L27/38 , A61L27/50 , A61L27/58 , B33Y80/00 , B41J3/407 , C12N5/0655 , C12N11/04 , C12N11/08 , C12N2533/54 , C12N2533/56 , D01D5/0007 , D01F6/625
Abstract: Provided herein is an apparatus for printing cells which includes an electrospinning device and an inkjet printing device operatively associated therewith. Methods of making a biodegradable scaffold having cells seeded therein are also provided. Methods of forming microparticles containing one or more cells encapsulated by a substrate are also provided, as are methods of forming an array of said microparticles.
Abstract translation: 本文提供了一种用于印刷电池的装置，其包括静电纺丝装置和与其可操作地相关联的喷墨打印装置。 还提供了制备具有种子细胞的可生物降解的支架的方法。 还提供了形成包含一个或多个由基底包封的细胞的微粒的方法，以及形成所述微粒阵列的方法。
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公开(公告)号：US20140199276A1
公开(公告)日：2014-07-17
申请号：US14185090
申请日：2014-02-20
Applicant: Wake Forest University Health Sciences
Inventor： Tao Xu , James J. Yoo , Anthony Atala , Dennis Dice
CPC classification number: A61K9/5089 , A61F2/062 , A61K35/32 , A61K35/34 , A61K35/36 , A61L27/38 , A61L27/50 , A61L27/58 , B33Y80/00 , B41J3/407 , C12N5/0655 , C12N11/04 , C12N11/08 , C12N2533/54 , C12N2533/56 , D01D5/0007 , D01F6/625
Abstract: Provided herein is an apparatus for printing cells which includes an electrospinning device and an inkjet printing device operatively associated therewith. Methods of making a biodegradable scaffold having cells seeded therein are also provided. Methods of forming microparticles containing one or more cells encapsulated by a substrate are also provided, as are methods of forming an array of said microparticles.
Abstract translation: 本文提供了一种用于印刷电池的装置，其包括静电纺丝装置和与其可操作地相关联的喷墨打印装置。 还提供了制备具有种子细胞的可生物降解的支架的方法。 还提供了形成包含一个或多个由基底包封的细胞的微粒的方法，以及形成所述微粒阵列的方法。
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