公开(公告)号：US10667897B2

公开(公告)日：2020-06-02

申请号：US15879301

申请日：2018-01-24

Applicant: University of Washington

Inventor： Buddy D. Ratner ,  Le Zhen ,  Felix Simonovsky ,  Jonathan Himmelfarb

IPC: A61F2/06 ,  A61L27/56 ,  A61L27/50 ,  A61L27/18 ,  A61L33/00 ,  A61L27/34

Abstract: Synthetic polymeric vascular grafts that promote endothelial healing and methods of their preparation and use are provided.

公开(公告)号：US20240279504A1

公开(公告)日：2024-08-22

申请号：US18465867

申请日：2023-09-12

Applicant: University of Washington

Inventor： Shaoyi Jiang ,  Xiaojie Lin ,  Jonathan Himmelfarb ,  Buddy D. Ratner

IPC: C09D133/26 ,  A61L29/04 ,  A61L29/06 ,  A61L29/08 ,  A61L29/14 ,  C08J3/28

CPC classification number: C09D133/26 ,  A61L29/041 ,  A61L29/06 ,  A61L29/085 ,  A61L29/141 ,  C08J3/28 ,  C08J2333/26

Abstract: Zwitterionic carboxybetaine copolymers and their use in coatings to impart non-fouling and functionality to surfaces, particularly surfaces of blood-contacting medical devices.

公开(公告)号：US20200261207A1

公开(公告)日：2020-08-20

申请号：US16861104

申请日：2020-04-28

Applicant: University of Washington

Inventor： Buddy D. Ratner ,  Le Zhen ,  Felix Simonovsky ,  Jonathan Himmelfarb

IPC: A61F2/06 ,  A61L27/56 ,  A61L27/50 ,  A61L27/18 ,  A61L33/00 ,  A61L27/34

Abstract: Synthetic polymeric vascular grafts that promote endothelial healing and methods of their preparation and use are provided.

公开(公告)号：US20230014056A1

公开(公告)日：2023-01-19

申请号：US17931474

申请日：2022-09-12

Applicant: University of Washington

Inventor： Shaoyi Jiang ,  Xiaojie Lin ,  Jonathan Himmelfarb ,  Buddy D. Ratner

IPC: C09D133/26 ,  A61L29/04 ,  A61L29/06 ,  A61L29/08 ,  A61L29/14 ,  C08J3/28

Abstract: Zwitterionic carboxybetaine copolymers and their use in coatings to impart non-fouling and functionality to surfaces, particularly surfaces of blood-contacting medical devices.

公开(公告)号：US11441049B2

公开(公告)日：2022-09-13

申请号：US17435654

申请日：2020-03-13

Applicant: University of Washington

Inventor： Shaoyi Jiang ,  Xiaojie Lin ,  Jonathan Himmelfarb ,  Buddy D. Ratner

IPC: C09D133/26 ,  C08J3/28 ,  A61L29/06 ,  A61L29/04 ,  A61L29/08 ,  A61L29/14

Abstract: Zwitterionic carboxybetaine copolymers and their use in coatings to impart non-fouling and functionality to surfaces, particularly surfaces of blood-contacting medical devices.

公开(公告)号：US12194196B2

公开(公告)日：2025-01-14

申请号：US16861104

申请日：2020-04-28

Applicant: University of Washington

Inventor： Buddy D. Ratner ,  Le Zhen ,  Felix Simonovsky ,  Jonathan Himmelfarb

IPC: A61F2/06 ,  A61L27/18 ,  A61L27/34 ,  A61L27/50 ,  A61L27/56 ,  A61L33/00

Abstract: Synthetic polymeric vascular grafts that promote endothelial healing and methods of their preparation and use are provided.

公开(公告)号：US20220000938A1

公开(公告)日：2022-01-06

申请号：US17284759

申请日：2019-10-14

Applicant: University of Washington

Inventor： Paul Yager ,  Jonathan Himmelfarb ,  Mari-Karoliina Henriikka Winkler ,  Erin Heiniger ,  Sujatha Kumar ,  David Stahl ,  Bruce Godfrey

IPC: A61K35/74 ,  A61K9/16

Abstract: Compositions and method for reducing the concentration of uremic toxins in the body of a patient suffering from some degree of kidney failure are disclosed. The methods can be used to delay the need for conventional dialysis treatment or as an adjunct therapy to reduce the frequency of dialysis sessions, and in some instances, as an alternative to such dialysis sessions.

公开(公告)号：US20180206971A1

公开(公告)日：2018-07-26

申请号：US15879301

申请日：2018-01-24

Applicant: University of Washington

Inventor： Buddy D. Ratner ,  Le Zhen ,  Felix Simonovsky ,  Jonathan Himmelfarb

IPC: A61F2/06 ,  A61L27/56 ,  A61L27/50

CPC classification number: A61F2/06 ,  A61F2250/0023 ,  A61F2250/0039 ,  A61F2250/0067 ,  A61L27/18 ,  A61L27/34 ,  A61L27/507 ,  A61L27/56 ,  A61L33/0011 ,  A61L2300/412 ,  A61L2300/42 ,  C08L75/04

Abstract: Synthetic polymeric vascular grafts that promote endothelial healing and methods of their preparation and use are provided.