公开(公告)号：US20240310344A1

公开(公告)日：2024-09-19

申请号：US18420137

申请日：2024-01-23

申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

发明人： Reginald M. Penner ,  Won-Tae Koo ,  Il-Doo Kim

IPC分类号： G01N33/00 ,  C23C14/58 ,  C25D1/04 ,  C25D3/50 ,  C25D5/02 ,  C25D5/40 ,  C25D5/48 ,  G01N27/12

CPC分类号： G01N33/005 ,  C23C14/5873 ,  C25D1/04 ,  C25D3/50 ,  C25D5/022 ,  C25D5/40 ,  C25D5/48 ,  G01N27/127

摘要： Systems and methods using engineered nanofiltration layers to facilitate acceleration of palladium nanowire hydrogen sensors. The sensors include a metal-organic framework (MOF) assembled on palladium (Pd) nanowires (NWs) for highly selective and ultra-fast H2 molecule detection.

公开(公告)号：US10818917B2

公开(公告)日：2020-10-27

申请号：US15934884

申请日：2018-03-23

申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

发明人： Girija Thesma Chandran ,  Reginald M. Penner

IPC分类号： H01M4/36 ,  H01G11/50 ,  H01G11/46 ,  H01G11/24 ,  H01M4/50 ,  H01M4/60 ,  H01M4/75 ,  C25D3/48 ,  C25D9/02 ,  C25D9/08 ,  C25D5/02 ,  C25D5/10 ,  C25D7/06 ,  G03F7/20 ,  H01G11/86 ,  C25D9/04 ,  C25D1/04 ,  C25D1/00 ,  H01M4/13 ,  H01M4/04 ,  H01M4/139 ,  H01G11/56 ,  H01M4/66 ,  H01M10/0525

摘要： Systems and methods that facilitate enhancing the energy storage capabilities of MnO2 in nanowire energy storage devices such as nanowire-based capacitors or batteries.

公开(公告)号：US20200152396A1

公开(公告)日：2020-05-14

申请号：US16426407

申请日：2019-05-30

申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

发明人： Reginald M. Penner ,  Mya Le Thai

IPC分类号： H01G11/36 ,  H01M10/0565 ,  H01M4/66 ,  B82Y30/00 ,  H01M12/02 ,  H01G11/80 ,  H01G11/24 ,  H01G11/56

摘要： A nanowire energy storage device such as a nanowire battery or a capacitor having a cathode comprising a plurality of nanowires and an anode comprising a plurality of nanowires interlaced with the plurality of nanowires of the cathode, and embedded in a PMMA gel electrolyte.

公开(公告)号：US10347434B2

公开(公告)日：2019-07-09

申请号：US15584652

申请日：2017-05-02

申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

发明人： Reginald M. Penner ,  Mya Le Thai

IPC分类号： H01G11/36 ,  H01G11/56 ,  H01G11/24 ,  H01G11/80 ,  H01M12/00 ,  H01M12/02 ,  B82Y30/00 ,  H01M4/66 ,  H01M10/0565 ,  H01M10/04 ,  B82Y40/00

摘要： A nanowire energy storage device such as a nanowire battery or a capacitor having a cathode comprising a plurality of nanowires and an anode comprising a plurality of nanowires interlaced with the plurality of nanowires of the cathode, and embedded in a PMMA gel electrolyte.

公开(公告)号：US09062353B2

公开(公告)日：2015-06-23

申请号：US13960703

申请日：2013-08-06

申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

发明人： Gregory A. Weiss ,  Reginald M. Penner ,  Jessica A. Arter ,  David K. Taggart ,  Keith C. Donavan

IPC分类号： C12Q1/70 ,  G01N27/12 ,  C12Q1/68

CPC分类号： C12Q1/70 ,  C12Q1/6825 ,  C12Q1/701 ,  G01N27/127 ,  C12Q2563/116 ,  C12Q2563/137 ,  C12Q2563/157

摘要： Grafting M13 bacteriophage into an array of poly(3,4-ethylenedioxythiophene) (PEDOT) nanowires generated hybrids of conducting polymers and replicable genetic packages (rgps) such as viruses. The incorporation of rgps into the polymeric backbone of PEDOT occurs during electropolymerization via lithographically patterned nanowire electrodeposition (LPNE). The resultant arrays of rgps-PEDOT nanowires enable real-time, reagent-free electrochemical biosensing of analytes in physiologically relevant buffers.

摘要翻译： 将M13噬菌体接枝到聚（3,4-乙烯二氧噻吩）（PEDOT）（PEDOT）纳米线阵列中，产生导电聚合物和可复制遗传包装（rgps）如病毒的杂交体。 通过光刻图案化的纳米线电沉积（LPNE）在电聚合过程中将rgps掺入PEDOT的聚合物骨架中。 所得到的rgps-PEDOT纳米线阵列使生物相关缓冲液中分析物的实时，无试剂电化学生物传感。

公开(公告)号：US11168306B2

公开(公告)日：2021-11-09

申请号：US15121153

申请日：2015-02-25

申请人： The Regents of the University of California

发明人： Gregory A. Weiss ,  Kritika Mohan ,  Lindsay Kindra ,  Reginald M. Penner

IPC分类号： C12Q1/00 ,  C12Q1/70 ,  C12N7/00 ,  G01N33/574 ,  C07D403/06 ,  G01N33/569 ,  G01N27/02 ,  G01N27/416

摘要： Disclosed herein, inter alia, are compositions and methods useful for improving detection of analytes. The compositions and methods provided include polymer-wrapped viral particles useful, inter alia, for the detection of PSMA.

公开(公告)号：US20200256838A1

公开(公告)日：2020-08-13

申请号：US16791159

申请日：2020-02-14

申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

发明人： Reginald M. Penner ,  Won-Tae Koo ,  Il-Doo Kim

IPC分类号： G01N33/00 ,  C25D3/50 ,  C25D5/40 ,  C25D5/48 ,  C23C14/58 ,  C25D1/04 ,  C25D5/02 ,  G01N27/12

摘要： Systems and methods using engineered nanofiltration layers to facilitate acceleration of palladium nanowire hydrogen sensors. The sensors include a metal-organic framework (MOF) assembled on palladium (Pd) nanowires (NWs) for highly selective and ultra-fast H2 molecule detection.

公开(公告)号：US20180294478A1

公开(公告)日：2018-10-11

申请号：US15934884

申请日：2018-03-23

申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

发明人： Girija Thesma Chandran ,  Reginald M. Penner

IPC分类号： H01M4/36 ,  H01G11/86 ,  H01G11/56 ,  H01G11/50 ,  H01G11/46 ,  H01G11/24 ,  H01M4/50 ,  H01M4/60 ,  H01M4/66 ,  H01M4/75 ,  H01M10/0525 ,  C25D3/48 ,  C25D9/02 ,  C25D9/08 ,  C25D5/02 ,  C25D5/10 ,  C25D7/06 ,  G03F7/20

CPC分类号： H01M4/366 ,  C25D1/006 ,  C25D1/04 ,  C25D3/48 ,  C25D5/022 ,  C25D5/10 ,  C25D7/0607 ,  C25D9/02 ,  C25D9/04 ,  C25D9/08 ,  G03F7/70058 ,  H01G11/24 ,  H01G11/46 ,  H01G11/50 ,  H01G11/56 ,  H01G11/86 ,  H01M4/0404 ,  H01M4/0452 ,  H01M4/13 ,  H01M4/139 ,  H01M4/364 ,  H01M4/502 ,  H01M4/60 ,  H01M4/661 ,  H01M4/667 ,  H01M4/75 ,  H01M10/0525 ,  H01M2300/0085

摘要： Systems and methods that facilitate enhancing the energy storage capabilities of MnO2 in nanowire energy storage devices such as nanowire-based capacitors or batteries.

公开(公告)号：US20170338056A1

公开(公告)日：2017-11-23

申请号：US15584652

申请日：2017-05-02

申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

发明人： Reginald M. Penner ,  Mya Le Thai

IPC分类号： H01G11/36 ,  H01G11/80 ,  H01G11/24 ,  H01G11/56 ,  H01M12/02 ,  H01M12/00

CPC分类号： H01G11/36 ,  B82Y30/00 ,  B82Y40/00 ,  H01G11/24 ,  H01G11/56 ,  H01G11/80 ,  H01M4/661 ,  H01M10/0565 ,  H01M12/005 ,  H01M12/02 ,  H01M2010/0495 ,  Y02E60/13

摘要： A nanowire energy storage device such as a nanowire battery or a capacitor having a cathode comprising a plurality of nanowires and an anode comprising a plurality of nanowires interlaced with the plurality of nanowires of the cathode, and embedded in a PMMA gel electrolyte.

公开(公告)号：US20140014536A1

公开(公告)日：2014-01-16

申请号：US13941231

申请日：2013-07-12

申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

发明人： Gregory A. Weiss ,  Reginald M. Penner ,  Phillip Y. Tam ,  Li-Mei Yang ,  Tyler Brigham

IPC分类号： G01N27/327

CPC分类号： G01N27/327 ,  G01N27/3277

摘要： A biosensor that is capable of detecting the presence and/or concentration of an analyte or biomarker includes at least one electrically conductive electrode operatively coupled to an impedance analyzer for measuring the change in the resistive impedance ΔZRe of the electrode in response to an applied alternating current at a plurality of frequencies. In one embodiment, at least one electrode is covered with a self-assembled monolayer that is chemically bonded to a surface. A plurality of virus particles such as phage viruses are immobilized on the self-assembled monolayer and may be exposed to a test or sample solution. The virus particles may be obtained from phage-displayed libraries to detect a wide variety of targets including, for example, DNA, RNA, small molecules, and proteins or polypeptides. In another embodiment, the virus particles are electrostatically bound to a substrate in between a pair of elongated electrodes disposed on a substrate.

摘要翻译： 能够检测分析物或生物标志物的存在和/或浓度的生物传感器包括至少一个可操作地耦合到阻抗分析器的导电电极，用于响应于施加的交流电流来测量电极的电阻阻抗DeltaZRe的变化 在多个频率处。 在一个实施方案中，至少一个电极被化学键合到表面的自组装单层覆盖。 多个病毒颗粒如噬菌体病毒固定在自组装单层上，并可暴露于测试或样品溶液中。 病毒颗粒可以从噬菌体展示的文库中获得，以检测多种靶，包括例如DNA，RNA，小分子和蛋白质或多肽。 在另一个实施方案中，病毒颗粒在布置在基底上的一对细长电极之间静电结合到基底上。