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公开(公告)号：US11164656B2
公开(公告)日：2021-11-02
申请号：US16107904
申请日：2018-08-21
IPC分类号： G06N7/00 , G16B30/10 , G16B30/00 , G16H50/20 , G06F40/169 , G16B20/20 , G16B40/00 , G06F3/0484 , G06T11/20 , C12Q1/6886 , G16H70/20 , G16H10/40 , G16H10/60
摘要： The present invention relates to methods for evaluating and/or predicting the outcome of a clinical condition, such as cancer, metastasis, AIDS, autism, Alzheimer's, and/or Parkinson's disorder. The methods can also be used to monitor and track changes in a patient's DNA and/or RNA during and following a clinical treatment regime. The methods may also be used to evaluate protein and/or metabolite levels that correlate with such clinical conditions. The methods are also of use to ascertain the probability outcome for a patient's particular prognosis.
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公开(公告)号：US11152080B2
公开(公告)日：2021-10-19
申请号：US15711487
申请日：2017-09-21
IPC分类号： G16B20/20 , G16B30/00 , G16H50/20 , G06F40/169 , G16B30/10 , G16B40/00 , G06F3/0484 , G06T11/20 , G06N7/00 , C12Q1/6886 , G16H70/20 , G16H10/40 , G16H10/60
摘要： The present invention relates to methods for evaluating and/or predicting the outcome of a clinical condition, such as cancer, metastasis, AIDS, autism, Alzheimer's, and/or Parkinson's disorder. The methods can also be used to monitor and track changes in a patient's DNA and/or RNA during and following a clinical treatment regime. The methods may also be used to evaluate protein and/or metabolite levels that correlate with such clinical conditions. The methods are also of use to ascertain the probability outcome for a patient's particular prognosis.
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公开(公告)号：US20180157791A1
公开(公告)日：2018-06-07
申请号：US15618003
申请日：2017-06-08
IPC分类号： G06F19/22 , G06N7/00 , G16H50/20 , G06F3/0484 , C12Q1/6886 , G06F17/24 , G06T11/20 , G16H10/40
CPC分类号： G16B30/00 , C12Q1/6886 , C12Q2600/106 , C12Q2600/118 , C12Q2600/156 , G06F3/04845 , G06F17/241 , G06F19/00 , G06F2203/04806 , G06N7/005 , G06Q50/24 , G06T11/206 , G16H10/40 , G16H10/60 , G16H50/20 , Y02A90/22 , Y02A90/26
摘要： The present invention relates to methods for evaluating and/or predicting the outcome of a clinical condition, such as cancer, metastasis, AIDS, autism, Alzheimer's, and/or Parkinson's disorder. The methods can also be used to monitor and track changes in a patient's DNA and/or RNA during and following a clinical treatment regime. The methods may also be used to evaluate protein and/or metabolite levels that correlate with such clinical conditions. The methods are also of use to ascertain the probability outcome for a patient's particular prognosis.
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4.发明申请BAMBAM: PARALLEL COMPARATIVE ANALYSIS OF HIGH-THROUGHPUT SEQUENCING DATA 审中-公开BAMBAM：高通量序列数据的并行比较分析公开(公告)号：US20170061071A1
公开(公告)日：2017-03-02
申请号：US15167507
申请日：2016-05-27
摘要： The present invention relates to methods for evaluating and/or predicting the outcome of a clinical condition, such as cancer, metastasis, AIDS, autism, Alzheimer's, and/or Parkinson's disorder. The methods can also be used to monitor and track changes in a patient's DNA and/or RNA during and following a clinical treatment regime. The methods may also be used to evaluate protein and/or metabolite levels that correlate with such clinical conditions. The methods are also of use to ascertain the probability outcome for a patient's particular prognosis.
摘要翻译： 本发明涉及用于评估和/或预测临床病症如癌症，转移，AIDS，自闭症，阿尔茨海默病和/或帕金森病的结果的方法。 该方法还可以用于在临床治疗方案期间和之后监测和跟踪患者的DNA和/或RNA中的变化。 所述方法还可用于评估与这些临床病症相关的蛋白质和/或代谢物水平。 该方法也可用于确定患者特定预后的概率结果。
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公开(公告)号：US12099012B2
公开(公告)日：2024-09-24
申请号：US17738251
申请日：2022-05-06
发明人： Victoria Ly , Pierre Baudin , Pattawong Pansodtee , Erik Jung , Robert Currie , David Haussler , Mircea Teodorescu
IPC分类号： G06T7/00 , C12M1/12 , G01N21/64 , G02B21/36 , G06T7/571 , H04N5/265 , H04N23/62 , H04N23/66 , H04N23/90
CPC分类号： G01N21/6458 , C12M25/06 , G01N21/6486 , G02B21/365 , G06T7/571 , H04N5/265 , H04N23/62 , H04N23/66 , H04N23/90 , G01N2201/021 , G01N2201/062 , G06T2207/10056 , G06T2207/10148 , G06T2207/30024 , G06T2207/30072
摘要： An imaging system includes an imaging device having a holder configured to hold a cell culture plate with a plurality of wells. The imaging device also includes an imaging assembly having a plurality of imaging units, each of which is configured to image one well of the plurality of wells. The imaging system also includes a storage platform in communication with the imaging device configured to receive a plurality of images from the imaging device. The system further includes a computer in communication with the imaging device and the storage platform. The computer is configured to control the imaging device and to display at least one image of the plurality of images.
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公开(公告)号：US11158397B2
公开(公告)日：2021-10-26
申请号：US16107786
申请日：2018-08-21
IPC分类号： G16B30/10 , G16B30/00 , G16H50/20 , G06F40/169 , G16B20/20 , G16B40/00 , G06F3/0484 , G06T11/20 , G06N7/00 , C12Q1/6886 , G16H70/20 , G16H10/40 , G16H10/60
摘要： The present invention relates to methods for evaluating and/or predicting the outcome of a clinical condition, such as cancer, metastasis, AIDS, autism, Alzheimer's, and/or Parkinson's disorder. The methods can also be used to monitor and track changes in a patient's DNA and/or RNA during and following a clinical treatment regime. The methods may also be used to evaluate protein and/or metabolite levels that correlate with such clinical conditions. The methods are also of use to ascertain the probability outcome for a patient's particular prognosis.
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公开(公告)号：US10706956B2
公开(公告)日：2020-07-07
申请号：US15808722
申请日：2017-11-09
IPC分类号： G16B30/00 , G16H50/20 , G06F3/0484 , G06F17/24 , G06T11/20 , G06N7/00 , C12Q1/6886 , G06F19/00 , G06Q50/24 , G16H10/40 , G16H10/60
摘要： Methods are provided for evaluating and/or predicting the outcome of a clinical condition, such as cancer, metastasis, AIDS, autism, Alzheimer's, and/or Parkinson's disorder. The methods can also be used to monitor and track changes in a patient's DNA and/or RNA during and following a clinical treatment regime. The methods may also be used to evaluate protein and/or metabolite levels that correlate with such clinical conditions. The methods are also of use to ascertain the probability outcome for a patient's particular prognosis.
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公开(公告)号：US20180046752A1
公开(公告)日：2018-02-15
申请号：US15667544
申请日：2017-08-02
摘要： The present invention relates to methods for evaluating the probability that a patient's diagnosis may be treated with a particular clinical regimen or therapy.
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公开(公告)号：US20170206316A1
公开(公告)日：2017-07-20
申请号：US15476337
申请日：2017-03-31
摘要： A differential sequence object is constructed on the basis of alignment of sub-strings via incremental synchronization of sequence strings using known positions of the sub-strings relative to a reference genome sequence. An output file is then generated that comprises only relevant changes with respect to the reference genome.
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10.发明申请PATHWAY RECOGNITION ALGORITHM USING DATA INTEGRATION ON GENOMIC MODELS (PARADIGM) 审中-公开使用数据集成在基因模型上的路径识别算法（PARADIGM）公开(公告)号：US20150142465A1
公开(公告)日：2015-05-21
申请号：US14577522
申请日：2014-12-19
CPC分类号： G16H50/30 , G06F16/2219 , G06F19/3456 , G06F19/3475 , G06F19/3481 , G16B5/00 , G16B25/00 , G16B40/00 , G16H20/10 , G16H20/30 , G16H20/60 , G16H50/20 , Y02A90/26
摘要： A patient sample specific dynamic pathway map is constructed on the basis of measured patient data and a probabilistic pathway model that is based on attributes for pathway elements, wherein some attributes for pathway elements are known a priori, where other attributes for the pathway elements are assumed, and where the pathway elements are cross-correlated and assigned an influence level for at least one pathway. Preferred dynamic pathway maps provide context of the measured patient data with respect to a selected reference pathway activity.
摘要翻译： 基于测量的患者数据和基于路径元件的属性的概率路径模型来构建患者样本特异性动态路径图，其中路径元素的一些属性先验已知，其中假定路径元件的其他属性 ，并且其中途径元件是交叉相关的并且被赋予至少一个途径的影响水平。 优选的动态路径图相对于所选择的参考途径活动提供所测量的患者数据的上下文。
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