专利检索 ap:("TEMASEK LIFE SCIENCES LABORATORY LIMITED") AND inv:"Chong Mei Koh" 第 1 页

1.

发明授权
Methods for efficient production of polyunsaturated fatty acids (PUFA) in Rhodosporidium and Rhodotorula species 有权

公开(公告)号：US10081821B2

公开(公告)日：2018-09-25

申请号：US15326077

申请日：2015-08-21

申请人： Temasek Life Sciences Laboratory Limited

发明人： Yanbin Liu , Chong Mei Koh , Lianghui Ji

IPC分类号： C12N1/14 , C12N1/15 , C12N9/02 , C12P7/64 , C12N15/52 , C12N15/81 , C12N9/04 , C12N9/10 , C12N9/88 , C12N9/90 , C12N9/00

摘要： The present invention relates to the field of fungal biotechnology, more particularly to genetic engineering methods for the production of polyunsaturated fatty acids (PUFA) in fungal hosts selected from Rhodosporidium and Rhodotorula genera. The present invention further relates to a modified fungal host cell having reduced native aldehyde dehydrogenase (ALD 1) enzyme activity, and methods for producing omega-3 and omega-6 fatty acids and triacylglycerides, by growing said fungal host cell under suitable conditions.

2.

发明授权
Methods for tuning carotenoid production levels and compositions in rhodosporidium and rhodotorula genera 有权

公开(公告)号：US10308691B2

公开(公告)日：2019-06-04

申请号：US15535466

申请日：2015-12-14

申请人： TEMASEK LIFE SCIENCES LABORATORY LIMITED

发明人： Yanbin Liu , Chong Mei Koh , Lianghui Ji

IPC分类号： C12N15/80 , C07K14/37 , C12P23/00 , C12N9/02 , C12N15/113 , C12P21/02

摘要： The present invention relates to the field of fungal biotechnology, more particularly to genetic engineering methods for the production of carotenoids in fungal hosts selected from Rhodospordium and Rhodotorula genera.