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公开(公告)号：US5573779A
公开(公告)日：1996-11-12
申请号：US313231
申请日：1994-09-30
Applicant: Shuji Sato , Iwao Nozawa , Katsuhiko Akiyama
Inventor： Shuji Sato , Iwao Nozawa , Katsuhiko Akiyama
CPC classification number: A61K9/127 , Y10S436/829
Abstract: A liposome composition which is effective in administering a physiologically active substance to Peyer's patches and is characterized by containing phosphatidylcholine, cholesterol and phosphatidylinositol as lipid components and having a high ability to migrate into Peyer's patches.
Abstract translation: PCT No.PCT / JP93 / 00460 Sec。 371日期1994年9月30日 102（e）1994年9月30日PCT 1993年4月9日PCT PCT。 公开号WO93 / 20801 日期：1993年10月28日一种脂质体组合物，其有效地将生理活性物质施用于派耶尔斑块，其特征在于含有磷脂酰胆碱，胆固醇和磷脂酰肌醇作为脂质成分并且具有高迁移到派尔氏贴剂的能力。
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公开(公告)号：US4968539A
公开(公告)日：1990-11-06
申请号：US277697
申请日：1988-11-30
Applicant: Takao Aoyagi , Shuji Sato , Minako Yasu , Iwao Nozawa , Yousuke Suzuki
Inventor： Takao Aoyagi , Shuji Sato , Minako Yasu , Iwao Nozawa , Yousuke Suzuki
CPC classification number: A61K9/009 , A61K9/703 , A61K9/7084 , B01D69/141 , C09K19/00 , C09K19/38 , Y10S428/913 , Y10T428/1059
Abstract: A polymer membrane for delivering a drug is provided. The membrane is capable of regulating the delivery of the drug and comprises (A) a porous hydrophobic polymer membrane having a pore diameter of not larger than 3 .mu.m and a porosity of 10 to 90% which is immobilized with (B) a specific liquid crystal-forming compound having a gel/liquid crystal transition temperature in the range of 25.degree. to 45.degree. C.
Abstract translation: 提供了用于递送药物的聚合物膜。 该膜能够调节药物的输送，并且包含（A）孔径不大于3μm的孔隙率为10〜90％的多孔疏水性聚合物膜，其固定有（B）特定液体 凝胶/液晶转变温度在25〜45℃范围内的结晶化合物
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公开(公告)号：US06978172B2
公开(公告)日：2005-12-20
申请号：US10335641
申请日：2002-12-30
Applicant: Kenji Mori , Iwao Nozawa , Shuji Sato
Inventor： Kenji Mori , Iwao Nozawa , Shuji Sato
CPC classification number: A61N1/0424 , A61N1/042 , A61N1/044 , A61N1/0444 , A61N1/327
Abstract: Electroporation electrodes are laminated to a permeable membrane to form an electrode membrane. Such an electrode membrane is useful for a continuous controlled delivery of a therapeutic agent through the skin or mucosa, when placed in direct contact with the skin or mucosa and by application of electric field pulses at specified intervals. An electrode membrane can be assembled such that it incorporates an iontophoretic electrode in the same device. This device can be jointly utilized for electroporation and iontophoretic drug delivery through the skin and mucosal membrane.
Abstract translation: 将电穿孔电极层压到可渗透膜上以形成电极膜。 当与皮肤或粘膜直接接触并且以规定的间隔施加电场脉冲时，这种电极膜可用于连续控制递送治疗剂通过皮肤或粘膜。 可以组装电极膜，使得其在同一装置中并入离子电渗电极。 该装置可以共同用于通过皮肤和粘膜的电穿孔和离子电渗药物递送。
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公开(公告)号：US06775569B2
公开(公告)日：2004-08-10
申请号：US08964872
申请日：1997-11-05
Applicant: Kenji Mori , Iwao Nozawa , Shuji Sato
Inventor： Kenji Mori , Iwao Nozawa , Shuji Sato
IPC: A61N130
CPC classification number: A61N1/0424 , A61N1/042 , A61N1/044 , A61N1/0444 , A61N1/327
Abstract: Electroporation electrodes are laminated to a permeable membrane to form an electrode membrane. Such an electrode membrane is useful for a continuous controlled delivery of a therapeutic agent through the skin or mucosa, when placed in direct contact with the skin or mucosa and by application of electric field pulses at specified intervals. An electrode membrane can be assembled such that it incorporates an iontophoretic electrode in the same device. This device can be jointly utilized for electroporation and iontophoretic drug delivery through the skin and mucosal membrane.
Abstract translation: 将电穿孔电极层压到可渗透膜上以形成电极膜。 当与皮肤或粘膜直接接触并且以规定的间隔施加电场脉冲时，这种电极膜可用于连续控制递送治疗剂通过皮肤或粘膜。 可以组装电极膜，使得其在同一装置中并入离子电渗电极。 该装置可以共同用于通过皮肤和粘膜的电穿孔和离子电渗药物递送。
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公开(公告)号：US06490482B2
公开(公告)日：2002-12-03
申请号：US09186564
申请日：1998-11-04
Applicant: Kenji Mori , Iwao Nozawa , Shuji Sato
Inventor： Kenji Mori , Iwao Nozawa , Shuji Sato
IPC: A61N130
CPC classification number: A61N1/0424 , A61N1/042 , A61N1/044 , A61N1/0444 , A61N1/327
Abstract: Electroporation electrodes are laminated to a permeable membrane to form an electrode membrane. Such an electrode membrane is useful for a continuous controlled delivery of a therapeutic agent through the skin or mucosa, when placed in direct contact with the skin or mucosa and by application of electric field pulses at specified intervals. An electrode membrane can be assembled such that it incorporates an iontophoretic electrode in the same device. This device can be jointly utilized for electroporation and iontophoretic drug delivery through the skin and mucosal membrane.
Abstract translation: 将电穿孔电极层压到可渗透膜上以形成电极膜。 当与皮肤或粘膜直接接触并且以规定的间隔施加电场脉冲时，这种电极膜可用于连续控制递送治疗剂通过皮肤或粘膜。 可以组装电极膜，使得其在同一装置中并入离子电渗电极。 该装置可以共同用于通过皮肤和粘膜的电穿孔和离子电渗药物递送。
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Patent Agency Ranking
6.发明授权Anti-histone H1 monoclonal antibody and hybridoma for the production thereof 有权抗组蛋白H1单克隆抗体和用于其生产的杂交瘤公开(公告)号：US08187602B2
公开(公告)日：2012-05-29
申请号：US12762649
申请日：2010-04-19
Applicant: Takeshi Goto , Shuji Sato , Kazuhisa Ono , Seiko Shigeta , Seiji Kawamoto , Shigeru Goto
Inventor： Takeshi Goto , Shuji Sato , Kazuhisa Ono , Seiko Shigeta , Seiji Kawamoto , Shigeru Goto
CPC classification number: C07K16/18 , C07K7/08 , C07K14/47 , Y10S530/808 , Y10S530/809
Abstract: The present invention discloses anti-histone H1 monoclonal antibodies, hybridomas for the production thereof, and polypeptides, which are useful for suppressing, predicting, or diagnosing transplant rejection in organ transplantation.
Abstract translation: 本发明公开了用于抑制，预测或诊断器官移植移植排斥反应的抗组蛋白H1单克隆抗体，其生产用杂交瘤和多肽。
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7.发明申请ELECTROSTATIC IMAGE DEVELOPING TONER, METHOD FOR PRODUCING ELECTROSTATIC IMAGE DEVELOPING TONER, METHOD FOR FORMING IMAGE, AND IMAGE FORMING APPARATUS. 有权静电图像显影调色剂，用于生产静电图像显影剂的方法，用于形成图像的方法和图像形成装置。公开(公告)号：US20110236817A1
公开(公告)日：2011-09-29
申请号：US12862247
申请日：2010-08-24
Applicant: Masaru Takahashi , Shinya Nakashima , Shuji Sato
Inventor： Masaru Takahashi , Shinya Nakashima , Shuji Sato
CPC classification number: G03G9/08797 , G03G9/08755 , G03G9/08773 , G03G9/08782 , G03G9/08795 , G03G15/2025 , G03G15/206 , G03G2215/2048
Abstract: An electrostatic image developing toner includes a binding resin and a release agent, wherein an organic silicon compound including a siloxane bond is present in a domain of the release agent.
Abstract translation: 静电图像显影调色剂包括粘合树脂和脱模剂，其中包含硅氧烷键的有机硅化合物存在于脱模剂的结构域中。
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公开(公告)号：US20110188910A1
公开(公告)日：2011-08-04
申请号：US12858780
申请日：2010-08-18
Applicant: Shinya NAKASHIMA , Shuji Sato , Masaru Takahashi
Inventor： Shinya NAKASHIMA , Shuji Sato , Masaru Takahashi
IPC: G03G15/20
CPC classification number: G03G15/20
Abstract: A fixing device is configured to fix a toner image formed on a recording medium and includes a fixing roll, a separation claw in contact with the fixing roll, and a pressure member disposed to face the fixing roll. The fixing roll includes a metallic core and a surface layer formed on the metallic core. The surface layer is an electroless nickel plating layer containing a boron compound and a phosphorus compound.
Abstract translation: 定影装置被配置为固定形成在记录介质上的调色剂图像，并且包括定影辊，与定影辊接触的分离爪和设置成面向定影辊的压力构件。 定影辊包括金属芯和形成在金属芯上的表面层。 表面层是含有硼化合物和磷化合物的化学镀镍层。
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公开(公告)号：US07964554B2
公开(公告)日：2011-06-21
申请号：US11661763
申请日：2005-09-05
Applicant: Takeshi Goto , Shuji Sato , Kazuhisa Ono , Seiko Shigeta , Seiji Kawamoto , Shigeru Goto
Inventor： Takeshi Goto , Shuji Sato , Kazuhisa Ono , Seiko Shigeta , Seiji Kawamoto , Shigeru Goto
CPC classification number: C07K16/18 , C07K7/08 , C07K14/47 , Y10S530/808 , Y10S530/809
Abstract: The present invention discloses anti-histone H1 monoclonal antibodies, hybridomas for the production thereof, and polypeptides, which are useful for suppressing, predicting, or diagnosing transplant rejection in organ transplantation.
Abstract translation: 本发明公开了用于抑制，预测或诊断器官移植移植排斥反应的抗组蛋白H1单克隆抗体，其生产用杂交瘤和多肽。
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公开(公告)号：US07723496B2
公开(公告)日：2010-05-25
申请号：US10525105
申请日：2003-08-20
Applicant: Takafumi Ishii , Koji Yamamoto , Eiji Sunahara , Shuji Sato
Inventor： Takafumi Ishii , Koji Yamamoto , Eiji Sunahara , Shuji Sato
CPC classification number: A61K45/06 , A61K38/1709 , A61K48/00 , C07K14/47 , C07K16/30 , C12Q1/6886 , C12Q2600/136 , G01N33/574 , A61K2300/00
Abstract: A compound inhibiting the activity of a protein comprising the same or substantially the same amino acid sequence as the amino acid sequence represented by SEQ ID NO: 1, SEQ ID NO: 4, SEQ ID NO: 7, SEQ ID NO: 10, SEQ ID NO: 15, SEQ ID NO: 17, SEQ ID NO: 20, SEQ ID NO: 22, SEQ ID NO: 25 or SEQ ID NO: 27, or a salt thereof; a compound inhibiting the expression of a gene of the protein; an antisense polynucleotide containing the entire or part of a base sequence complementary or substantially complementary to a base sequence of a polynucleotide encoding the protein or its partial peptide; an antibody to the protein or its partial peptide, etc. are useful as prophylactic/therapeutic agents for cancer, etc., apoptosis promoters for cancer cells, and the like.
Abstract translation: 抑制蛋白质活性的化合物，其包含与SEQ ID NO：1，SEQ ID NO：4，SEQ ID NO：7，SEQ ID NO：10，SEQ ID NO：10所示的氨基酸序列相同或基本相同的氨基酸序列 SEQ ID NO：17，SEQ ID NO：20，SEQ ID NO：22，SEQ ID NO：25或SEQ ID NO：27，或其盐; 抑制蛋白质基因表达的化合物; 含有与编码该蛋白质或其部分肽的多核苷酸的碱基序列互补或基本上互补的全部或部分碱基序列的反义多核苷酸; 对蛋白质或其部分肽的抗体等可用作癌症等的预防/治疗剂，癌细胞的凋亡启动子等。
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