-
公开(公告)号：US20120295326A1
公开(公告)日：2012-11-22
申请号：US13562881
申请日：2012-07-31
Applicant: Sanjiv S. Gambhir , Andreas M. Loening , Anna M. Wu
Inventor： Sanjiv S. Gambhir , Andreas M. Loening , Anna M. Wu
CPC classification number: C12Q1/66
Abstract: Briefly described, embodiments of this disclosure include polynucleotides that encode mutant Cnidarian luciferases that exhibit modulated properties as compared to the corresponding wild-type luciferases, and the modulated properties include at least one of: modulated stability; enhanced light output; and modulated emission maximum. Embodiments of the present disclosure also include polypeptides or fragments thereof encoded by the polynucleotides, constructs including the polynucleotide, expression cassettes, cells, methods of producing the polynucleotides and polypeptides, antibodies, transgenic cells and/or animals, kits, and the like.
Abstract translation: 简要描述，本公开的实施方案包括编码与相应的野生型萤光素酶相比表现出调节特性的突变型雀巢萤光素酶的多核苷酸，并且调节的性质包括以下至少一种：调节的稳定性; 增强光输出; 并调制发射最大值。 本公开的实施方案还包括由多核苷酸编码的多肽或其片段，包括多核苷酸的构建体，表达盒，细胞，产生多核苷酸和多肽的方法，抗体，转基因细胞和/或动物，试剂盒等。
-
公开(公告)号：US08173791B2
公开(公告)日：2012-05-08
申请号：US13070665
申请日：2011-03-24
Applicant: Sanjiv S. Gambhir , Andreas M. Loening , Anna M. Wu
Inventor： Sanjiv S. Gambhir , Andreas M. Loening , Anna M. Wu
CPC classification number: C12Q1/66
Abstract: Briefly described, embodiments of this disclosure include polynucleotides that encode mutant Cnidarian luciferases that exhibit modulated properties as compared to the corresponding wild-type luciferases, and the modulated properties include at least one of: modulated stability; enhanced light output; and modulated emission maximum. Embodiments of the present disclosure also include polypeptides or fragments thereof encoded by the polynucleotides, constructs including the polynucleotide, expression cassettes, cells, methods of producing the polynucleotides and polypeptides, antibodies, transgenic cells and/or animals, kits, and the like.
Abstract translation: 简要描述，本公开的实施方案包括编码与相应的野生型萤光素酶相比表现出调节特性的突变型雀巢萤光素酶的多核苷酸，并且调节的性质包括以下至少一种：调节的稳定性; 增强光输出; 并调制发射最大值。 本公开的实施方案还包括由多核苷酸编码的多肽或其片段，包括多核苷酸的构建体，表达盒，细胞，产生多核苷酸和多肽的方法，抗体，转基因细胞和/或动物，试剂盒等。
-
公开(公告)号：US08378086B2
公开(公告)日：2013-02-19
申请号：US13562881
申请日：2012-07-31
Applicant: Sanjiv S. Gambhir , Andreas M. Loening , Anna M. Wu
Inventor： Sanjiv S. Gambhir , Andreas M. Loening , Anna M. Wu
CPC classification number: C12Q1/66
Abstract: Briefly described, embodiments of this disclosure include polynucleotides that encode mutant Cnidarian luciferases that exhibit modulated properties as compared to the corresponding wild-type luciferases, and the modulated properties include at least one of: modulated stability; enhanced light output; and modulated emission maximum. Embodiments of the present disclosure also include polypeptides or fragments thereof encoded by the polynucleotides, constructs including the polynucleotide, expression cassettes, cells, methods of producing the polynucleotides and polypeptides, antibodies, transgenic cells and/or animals, kits, and the like.
Abstract translation: 简要描述，本公开的实施方案包括编码与相应的野生型萤光素酶相比表现出调节特性的突变型雀巢萤光素酶的多核苷酸，并且调节的性质包括以下至少一种：调节的稳定性; 增强光输出; 并调制发射最大值。 本公开的实施方案还包括由多核苷酸编码的多肽或其片段，包括多核苷酸的构建体，表达盒，细胞，产生多核苷酸和多肽的方法，抗体，转基因细胞和/或动物，试剂盒等。
-
公开(公告)号：US08258277B2
公开(公告)日：2012-09-04
申请号：US13426790
申请日：2012-03-22
Applicant: Sanjiv S. Gambhir , Andreas M. Loening , Anna M. Wu
Inventor： Sanjiv S. Gambhir , Andreas M. Loening , Anna M. Wu
CPC classification number: C12Q1/66
Abstract: Briefly described, embodiments of this disclosure include polynucleotides that encode mutant Cnidarian luciferases that exhibit modulated properties as compared to the corresponding wild-type luciferases, and the modulated properties include at least one of: modulated stability; enhanced light output; and modulated emission maximum. Embodiments of the present disclosure also include polypeptides or fragments thereof encoded by the polynucleotides, constructs including the polynucleotide, expression cassettes, cells, methods of producing the polynucleotides and polypeptides, antibodies, transgenic cells and/or animals, kits, and the like.
-
公开(公告)号：US20090136998A1
公开(公告)日：2009-05-28
申请号：US11995586
申请日：2006-09-06
Applicant: Sanjiv S. Gambhir , Andreas M. Loening , Anna M. Wu
Inventor： Sanjiv S. Gambhir , Andreas M. Loening , Anna M. Wu
CPC classification number: C12Q1/66
Abstract: Briefly described, embodiments of this disclosure include polynucleotides that encode mutant Cnidarian luciferases that exhibit modulated properties as compared to the corresponding wild-type luciferases, and the modulated properties include at least one of: modulated stability; enhanced light output; and modulated emission maximum. Embodiments of the present disclosure also include polypeptides or fragments thereof encoded by the polynucleotides, constructs including the polynucleotide, expression cassettes, cells, methods of producing the polynucleotides and polypeptides, antibodies, transgenic cells and/or animals, kits, and the like.
Abstract translation: 简要描述，本公开的实施方案包括编码与相应的野生型萤光素酶相比表现出调节特性的突变型雀巢萤光素酶的多核苷酸，并且调节的性质包括以下至少一种：调节的稳定性; 增强光输出; 并调制发射最大值。 本公开的实施方案还包括由多核苷酸编码的多肽或其片段，包括多核苷酸的构建体，表达盒，细胞，产生多核苷酸和多肽的方法，抗体，转基因细胞和/或动物，试剂盒等。
-
Patent Agency Ranking
公开(公告)号：US07939649B2
公开(公告)日：2011-05-10
申请号：US11995586
申请日：2006-09-06
Applicant: Sanjiv S. Gambhir , Andreas M. Loening , Anna M. Wu
Inventor： Sanjiv S. Gambhir , Andreas M. Loening , Anna M. Wu
CPC classification number: C12Q1/66
Abstract: Briefly described, embodiments of this disclosure include polynucleotides that encode mutant Cnidarian luciferases that exhibit modulated properties as compared to the corresponding wild-type luciferases, and the modulated properties include at least one of: modulated stability; enhanced light output; and modulated emission maximum. Embodiments of the present disclosure also include polypeptides or fragments thereof encoded by the polynucleotides, constructs including the polynucleotide, expression cassettes, cells, methods of producing the polynucleotides and polypeptides, antibodies, transgenic cells and/or animals, kits, and the like.
Abstract translation: 简要描述，本公开的实施方案包括编码与相应的野生型萤光素酶相比表现出调节特性的突变型雀巢萤光素酶的多核苷酸，并且调节的性质包括以下至少一种：调节的稳定性; 增强光输出; 并调制发射最大值。 本公开的实施方案还包括由多核苷酸编码的多肽或其片段，包括多核苷酸的构建体，表达盒，细胞，产生多核苷酸和多肽的方法，抗体，转基因细胞和/或动物，试剂盒等。
-
公开(公告)号：US20120178141A1
公开(公告)日：2012-07-12
申请号：US13426790
申请日：2012-03-22
Applicant: Sanjiv S. Gambhir , Andreas M. Loening , Anna M. Wu
Inventor： Sanjiv S. Gambhir , Andreas M. Loening , Anna M. Wu
CPC classification number: C12Q1/66
Abstract: Briefly described, embodiments of this disclosure include polynucleotides that encode mutant Cnidarian luciferases that exhibit modulated properties as compared to the corresponding wild-type luciferases, and the modulated properties include at least one of: modulated stability; enhanced light output; and modulated emission maximum. Embodiments of the present disclosure also include polypeptides or fragments thereof encoded by the polynucleotides, constructs including the polynucleotide, expression cassettes, cells, methods of producing the polynucleotides and polypeptides, antibodies, transgenic cells and/or animals, kits, and the like.
-
公开(公告)号：US20110229955A1
公开(公告)日：2011-09-22
申请号：US13070665
申请日：2011-03-24
Applicant: Sanjiv S. Gambhir , Andreas M. Loening , Anna M. Wu
Inventor： Sanjiv S. Gambhir , Andreas M. Loening , Anna M. Wu
CPC classification number: C12Q1/66
Abstract: Briefly described, embodiments of this disclosure include polynucleotides that encode mutant Cnidarian luciferases that exhibit modulated properties as compared to the corresponding wild-type luciferases, and the modulated properties include at least one of: modulated stability; enhanced light output; and modulated emission maximum. Embodiments of the present disclosure also include polypeptides or fragments thereof encoded by the polynucleotides, constructs including the polynucleotide, expression cassettes, cells, methods of producing the polynucleotides and polypeptides, antibodies, transgenic cells and/or animals, kits, and the like.
Abstract translation: 简要描述，本公开的实施方案包括编码与相应的野生型萤光素酶相比表现出调节特性的突变型雀巢萤光素酶的多核苷酸，并且调节的性质包括以下至少一种：调节的稳定性; 增强光输出; 并调制发射最大值。 本公开的实施方案还包括由多核苷酸编码的多肽或其片段，包括多核苷酸的构建体，表达盒，细胞，产生多核苷酸和多肽的方法，抗体，转基因细胞和/或动物，试剂盒等。
-
公开(公告)号：US20090004117A1
公开(公告)日：2009-01-01
申请号：US12159150
申请日：2007-01-04
Applicant: Jianghong Rao , Min-kyung So , Chenjie Xu , Andreas M. Loening , Sanjiv S. Gambhir
Inventor： Jianghong Rao , Min-kyung So , Chenjie Xu , Andreas M. Loening , Sanjiv S. Gambhir
CPC classification number: G01N33/543 , B82Y15/00 , G01N21/763 , G01N33/588
Abstract: Generally, aspects of the present disclosure are directed to conjugate systems, self-illuminating quantum dot conjugates, methods of detecting a target in a host, methods of treating a disease in a host, and the like.
Abstract translation: 通常，本公开的方面涉及共轭系统，自发光量子点缀合物，检测宿主中靶标的方法，治疗宿主中的疾病的方法等。
-
公开(公告)号：US20120269734A1
公开(公告)日：2012-10-25
申请号：US13495208
申请日：2012-06-13
Applicant: Jianghong Rao , Min-kyung So , Chenjie Xu , Andreas M. Loening , Sanjiv S. Gambhir
Inventor： Jianghong Rao , Min-kyung So , Chenjie Xu , Andreas M. Loening , Sanjiv S. Gambhir
CPC classification number: G01N33/543 , B82Y15/00 , G01N21/763 , G01N33/588
Abstract: Generally, aspects of the present disclosure are directed to conjugate systems, self-illuminating quantum dot conjugates, methods of detecting a target in a host, methods of treating a disease in a host, and the like.
Abstract translation: 通常，本公开的方面涉及共轭系统，自发光量子点缀合物，检测宿主中靶标的方法，治疗宿主中的疾病的方法等。
-
-
-
-
-
-
-
-
-
Search Results
12
records
(took 0.033 seconds)
