Apparatus and means for handling cells
    4.
    发明授权
    Apparatus and means for handling cells 失效
    装置和手段处理细胞

    公开(公告)号:US3591460A

    公开(公告)日:1971-07-06

    申请号:US3591460D

    申请日:1967-08-30

    申请人: SMITH DAVID F

    发明人: SMITH DAVID F

    IPC分类号: C12M3/02 C12B1/10 C12K1/10

    摘要: A FUNNEL-SHAPED CHAMBER APPARATUS IS PROVIDED FOR PASSAGE THERETHROUGH OF UPWARDLY FLOWING FLUID MEDIUM ADAPTED FOR THE MAINTENANCE AND/OR GROWTH OF LIVING CELLS IN SUSPENSION. IN USE, THE MEDIUM AND THE CELLS ARE INTRODUCED INTO THE CHAMBER AND FRESH MEDIUM IS PUT IN AT A CONTINUOUS RATE AT LEAST SUFFICIENT TO KEEP THE CELLS SUSPENDED. THE LIVING CELL POPULATION DISTRIBUTES ACCORDING TO SIZE VERTICALLY IN THE CHAMBER (OR SERIES OF SUCCESSIVELY LARGER CHAMBERS) AND THUS CAN BE FRACTIONATED FOR SIZE. ALSO, BACTERIA, VIRUSES AND OTHER MICROBIOLOGICAL ENTITIES AS DESIRED CAN BE CONTINUOUSLY CULTIVATED ON THE LIVING CELLS FOR HARVESTING EITHER INTERMITTENTLY OR CONTINUOUSLY.